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TWO SIGMA INVESTMENTS, LP: RPRX position timeline

Available 13F reports, 13D and 13G stakes and each Form 3, 4 and 5 line of TWO SIGMA INVESTMENTS, LP on RPRX, newest first. How the timeline and the estimate are built.

TWO SIGMA INVESTMENTS, LP held 2,920,163 RPRX shares at 2026-06-30 per its 13F-HR filed 2026-08-14.

the latest 13F is the newest step

  1. period ended2026-06-30
    13F 2,920,163 shares
    Change vs previous 13F +668,638 shares

    0.12% of the 13F portfolio, value $163,733,539.

    13F-HR 0000899140-26-000855 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  2. period ended2026-03-31
    13F 2,251,525 shares
    Share basis changed not comparable

    Membership change: TWO SIGMA ADVISERS, LP left the group. 0.09% of the 13F portfolio, value $108,005,654.

    13F-HR 0000899140-26-000547 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  3. period ended2025-12-31
    13F 1,101,248 shares
    Change vs previous 13F -740,263 shares

    0.04% of the 13F portfolio, value $42,552,223.

    13F-HR 0000899140-26-000232 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 681,248 shares
    • TWO SIGMA ADVISERS, LP: 420,000 shares

    Acceptance time not in the bulk data set (spec §4.2).

  4. period ended2025-09-30
    13F 1,841,511 shares
    Change vs previous 13F +940,509 shares

    0.06% of the 13F portfolio, value $64,968,508.

    13F-HR 0000899140-25-001286 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 1,184,311 shares
    • TWO SIGMA ADVISERS, LP: 657,200 shares

    Acceptance time not in the bulk data set (spec §4.2).

  5. period ended2025-06-30
    13F 901,002 shares
    Change vs previous 13F -3,615,907 shares

    0.03% of the 13F portfolio, value $32,463,102.

    13F-HR 0000899140-25-000953 filed by TWO SIGMA ADVISERS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 54,102 shares
    • TWO SIGMA ADVISERS, LP: 846,900 shares

    Acceptance time not in the bulk data set (spec §4.2).

  6. period ended2025-03-31
    13F 4,516,909 shares
    Change vs previous 13F -1,576,694 shares

    0.16% of the 13F portfolio, value $140,611,377.

    13F-HR 0000899140-25-000679 filed by TWO SIGMA ADVISERS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 1,613,009 shares
    • TWO SIGMA ADVISERS, LP: 2,903,900 shares

    Acceptance time not in the bulk data set (spec §4.2).

  7. period ended2024-12-31
    13F 6,093,603 shares
    Change vs previous 13F +631,067 shares

    0.18% of the 13F portfolio, value $155,447,813.

    13F-HR 0000899140-25-000264 filed by TWO SIGMA ADVISERS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 2,420,403 shares
    • TWO SIGMA ADVISERS, LP: 3,673,200 shares

    Acceptance time not in the bulk data set (spec §4.2).

  8. period ended2024-09-30
    13F 5,462,536 shares
    Change vs previous 13F not available

    0.18% of the 13F portfolio, value $154,535,143.

    13F-HR 0000919574-24-006607 filed by TWO SIGMA ADVISERS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 2,429,336 shares
    • TWO SIGMA ADVISERS, LP: 3,033,200 shares

    Acceptance time not in the bulk data set (spec §4.2).