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TWO SIGMA INVESTMENTS, LP: IRWD position timeline

Available 13F reports, 13D and 13G stakes and each Form 3, 4 and 5 line of TWO SIGMA INVESTMENTS, LP on IRWD, newest first. How the timeline and the estimate are built.

TWO SIGMA INVESTMENTS, LP held 4,556,089 IRWD shares at 2026-06-30 per its 13F-HR filed 2026-08-14.

the latest 13F is the newest step

  1. period ended2026-06-30
    13F 4,556,089 shares
    Change vs previous 13F -1,292,187 shares

    0.01% of the 13F portfolio, value $19,181,135.

    13F-HR 0000899140-26-000855 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  2. period ended2026-03-31
    13F 5,848,276 shares
    Share basis changed not comparable

    Membership change: TWO SIGMA ADVISERS, LP left the group. 0.02% of the 13F portfolio, value $20,527,449.

    13F-HR 0000899140-26-000547 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  3. period ended2025-12-31
    13F 5,993,305 shares
    Change vs previous 13F +142,294 shares

    0.02% of the 13F portfolio, value $20,197,438.

    13F-HR 0000899140-26-000225 filed by TWO SIGMA ADVISERS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 2,853,205 shares
    • TWO SIGMA ADVISERS, LP: 3,140,100 shares

    Acceptance time not in the bulk data set (spec §4.2).

  4. period ended2025-09-30
    13F 5,851,011 shares
    Change vs previous 13F -283,662 shares

    0.01% of the 13F portfolio, value $7,664,824.

    13F-HR 0000899140-25-001279 filed by TWO SIGMA ADVISERS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 2,534,511 shares
    • TWO SIGMA ADVISERS, LP: 3,316,500 shares

    Acceptance time not in the bulk data set (spec §4.2).

  5. period ended2025-06-30
    13F 6,134,673 shares
    Change vs previous 13F +3,022,877 shares

    <0.01% of the 13F portfolio, value $4,399,788.

    13F-HR 0000899140-25-000953 filed by TWO SIGMA ADVISERS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 2,750,573 shares
    • TWO SIGMA ADVISERS, LP: 3,384,100 shares

    Acceptance time not in the bulk data set (spec §4.2).

  6. period ended2025-03-31
    13F 3,111,796 shares
    Change vs previous 13F +1,014,368 shares

    0.01% of the 13F portfolio, value $4,574,340.

    13F-HR 0000899140-25-000679 filed by TWO SIGMA ADVISERS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 1,227,196 shares
    • TWO SIGMA ADVISERS, LP: 1,884,600 shares

    Acceptance time not in the bulk data set (spec §4.2).

  7. period ended2024-12-31
    13F 2,097,428 shares
    Change vs previous 13F -54,035 shares

    0.01% of the 13F portfolio, value $9,291,606.

    13F-HR 0000899140-25-000264 filed by TWO SIGMA ADVISERS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 863,428 shares
    • TWO SIGMA ADVISERS, LP: 1,234,000 shares

    Acceptance time not in the bulk data set (spec §4.2).

  8. period ended2024-09-30
    13F 2,151,463 shares
    Change vs previous 13F not available

    0.01% of the 13F portfolio, value $8,864,028.

    13F-HR 0000919574-24-006607 filed by TWO SIGMA ADVISERS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 890,963 shares
    • TWO SIGMA ADVISERS, LP: 1,260,500 shares

    Acceptance time not in the bulk data set (spec §4.2).