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TRV GP IV, LLC

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13F filer, CIK 1688325, Boston, MA

TRV GP IV, LLC reported $273,955,121 across 2 holdings for the quarter ended 2025-09-30, in a 13F-HR filed 2025-11-13.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001193125-25-280198

Period
2025-09-30
Reported value
$274M
Holdings
2
Top 10 weight
100%
New
0
Sold out
1

Largest buys vs the previous quarter

None.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
TNGXreduced-2,995,100-$25.2M
PLRXexited-2,132,867-$2.47M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q3 2025

Share positions as resolved from 13F-HR 0001193125-25-280198, largest first. % of portfolio is the value over $273,955,121, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
MAZEMAZE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 6,073,958 shares; 2025Q2: 6,073,958 shares; 2025Q3: 6,073,958 shares 6,073,958$157M57.49%0Timeline
TNGXTANGO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 16,859,075 shares; 2024Q4: 16,859,075 shares; 2025Q1: 16,859,075 shares; 2025Q2: 16,859,075 shares; 2025Q3: 13,863,975 shares 13,863,975$116M42.51%-2,995,100Timeline

Sold out in Q3 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
PLRXPLIANT THERAPEUTICS INC2,132,867$2.47Mshares

How Q3 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001193125-25-280198 base2025-11-13acceptance time not in the bulk data set