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Propel Bio Management, LLC

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13F filer, CIK 1969764, Los Angeles, CA

Propel Bio Management, LLC reported $82,391,669 across 16 holdings for the quarter ended 2025-06-30, in a 13F-HR filed 2025-08-13. Its ten largest share positions make up 97.53% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0000898432-25-000591

Period
2025-06-30
Reported value
$82.4M
Holdings
16
Top 10 weight
97.53%
New
2
Sold out
4

Largest buys vs the previous quarter

SecurityShares changeApprox. value
ACHVadded+3,699,999$8.36M
ABEOadded+350,000$1.99M
CAPRnew+70,000$695K
MISTadded+340,000$660K
DCTHadded+48,452$659K

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
MDGLexited-30,032-$9.95M
RNAMexited-178,500-$5.27M
SNDXexited-183,259-$2.25M
PHATreduced-212,000-$2.03M
CMPXexited-228,317-$434K

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q2 2025

Share positions as resolved from 13F-HR 0000898432-25-000591, largest first. % of portfolio is the value over $82,391,669, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
PAGPPLAINS GP HLDGS L PQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,272,360 shares; 2024Q4: 1,272,360 shares; 2025Q1: 1,272,360 shares; 2025Q2: 1,272,360 shares 1,272,360$24.7M30.01%0Timeline
ACHVACHIEVE LIFE SCIENCE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,453,092 shares; 2024Q4: 2,453,092 shares; 2025Q1: 2,453,092 shares; 2025Q2: 6,153,091 shares 6,153,091$13.9M16.88%+3,699,999Timeline
AKROAKERO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 343,729 shares; 2024Q4: 343,729 shares; 2025Q1: 228,884 shares; 2025Q2: 228,884 shares 228,884$12.2M14.82%0Timeline
PHATPHATHOM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 869,927 shares; 2024Q4: 989,927 shares; 2025Q1: 1,134,927 shares; 2025Q2: 922,927 shares 922,927$8.85M10.74%-212,000Timeline
ABEOABEONA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 624,022 shares; 2024Q4: 624,022 shares; 2025Q1: 624,022 shares; 2025Q2: 974,022 shares 974,022$5.53M6.71%+350,000Timeline
Applied Therapeutics IncApplied Therapeutics IncQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 6,567,858 shares; 2024Q4: 9,615,420 shares; 2025Q1: 11,285,420 shares; 2025Q2: 11,285,420 shares 11,285,420$3.51M4.26%0
MISTMILESTONE PHARMACEUTICALS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 1,451,557 shares; 2025Q2: 1,791,557 shares 1,791,557$3.48M4.22%+340,000Timeline
DCTHDELCATH SYS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 17,000 shares; 2025Q1: 177,600 shares; 2025Q2: 226,052 shares 226,052$3.07M3.73%+48,452Timeline
TCRXTSCAN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,087,139 shares; 2024Q4: 2,087,139 shares; 2025Q1: 2,087,139 shares; 2025Q2: 2,087,139 shares 2,087,139$3.03M3.67%0Timeline
ZVRAZEVRA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 179,874 shares; 2024Q4: 179,874 shares; 2025Q1: 179,874 shares; 2025Q2: 231,874 shares 231,874$2.04M2.48%+52,000Timeline
CAPRCAPRICOR THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 70,000 shares 70,000$695K0.84%newTimeline
MAAT PHARMA SACAMAAT PHARMA SACAQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,397 shares; 2024Q4: 3,151 shares; 2025Q1: 166,423 shares; 2025Q2: 94,181 shares 94,181$452K0.55%-72,242
ATHIRA PHARMA INCATHIRA PHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,492,792 shares; 2024Q4: 1,492,792 shares; 2025Q1: 1,492,792 shares; 2025Q2: 1,492,792 shares 1,492,792$451K0.55%0
EIGRQEIGER BIOPHARMACEUTICALSQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 146,381 shares; 2024Q4: 146,381 shares; 2025Q1: 146,381 shares; 2025Q2: 146,381 shares 146,381$423K0.51%0Timeline
WTS - Achieve Life SciWTS - Achieve Life SciQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 3,699,999 shares 3,699,999$13.7K0.02%new
CHINOOK THERAPEUTICS CVRCHINOOK THERAPEUTICS CVRQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 79,357 shares; 2024Q4: 79,357 shares; 2025Q1: 79,357 shares; 2025Q2: 79,357 shares 79,357$2.5K<0.01%0

Sold out in Q2 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
MDGLMADRIGAL PHARMACEUTICALS INC30,032$9.95Mshares
RNAMAVIDITY BIOSCIENCES INC178,500$5.27Mshares
SNDXSYNDAX PHARMACEUTICALS INC183,259$2.25Mshares
CMPXCOMPASS THERAPEUTICS INC228,317$434Kshares

How Q2 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0000898432-25-000591 base2025-08-13acceptance time not in the bulk data set