IOVA IOVANCE BIOTHERAPEUTICS INC More: the full row for IOVANCE BIOTHERAPEUTICS INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 912,987 shares; 2018Q2: 4,146,605 shares; 2018Q3: 4,894,361 shares; 2018Q4: 5,951,153 shares 5,951,153 $52.7M 10.85% +1,056,792 Timeline TESARO INC TESARO INC More: the full row for TESARO INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: not reported; 2018Q3: 104,700 shares; 2018Q4: 442,219 shares 442,219 $32.8M 6.77% +337,519 NEVRO CORP NEVRO CORP More: the full row for NEVRO CORP Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: not reported; 2018Q3: not reported; 2018Q4: 744,415 shares 744,415 $28.9M 5.97% new ARATANA THERAPEUTICS INC ARATANA THERAPEUTICS INC More: the full row for ARATANA THERAPEUTICS INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 4,294,426 shares; 2018Q2: 4,294,426 shares; 2018Q3: 4,083,135 shares; 2018Q4: 4,083,135 shares 4,083,135 $25M 5.16% 0 RETROPHIN INC RETROPHIN INC More: the full row for RETROPHIN INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 1,178,226 shares; 2018Q2: 1,048,693 shares; 2018Q3: 938,214 shares; 2018Q4: 1,016,114 shares 1,016,114 $23M 4.74% +77,900 ADAMAS PHARMACEUTICALS INC ADAMAS PHARMACEUTICALS INC More: the full row for ADAMAS PHARMACEUTICALS INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 1,135,203 shares; 2018Q2: 1,417,121 shares; 2018Q3: 1,328,424 shares; 2018Q4: 2,614,468 shares 2,614,468 $22.3M 4.6% +1,286,044 DXCM DEXCOM INC More: the full row for DEXCOM INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: not reported; 2018Q3: 24,200 shares; 2018Q4: 179,900 shares 179,900 $21.6M 4.44% +155,700 Timeline ZOGENIX INC. ZOGENIX INC. More: the full row for ZOGENIX INC. Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 537,380 shares; 2018Q2: 622,380 shares; 2018Q3: 657,898 shares; 2018Q4: 535,998 shares 535,998 $19.5M 4.03% -121,900 LA JOLLA PHARMACEUTICAL CO LA JOLLA PHARMACEUTICAL CO More: the full row for LA JOLLA PHARMACEUTICAL CO Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 1,656,720 shares; 2018Q2: 1,494,520 shares; 2018Q3: 2,053,991 shares; 2018Q4: 1,947,541 shares 1,947,541 $18.4M 3.78% -106,450 BIODELIVERY SCIENCES INTL IN BIODELIVERY SCIENCES INTL IN More: the full row for BIODELIVERY SCIENCES INTL IN Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 4,278,819 shares; 2018Q2: 4,278,819 shares; 2018Q3: 4,375,066 shares; 2018Q4: 4,375,066 shares 4,375,066 $16.2M 3.34% 0 SOCIETAL CDMO INC SOCIETAL CDMO INC More: the full row for SOCIETAL CDMO INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 2,236,025 shares; 2018Q2: 2,048,025 shares; 2018Q3: 2,048,025 shares; 2018Q4: 2,048,025 shares 2,048,025 $14.5M 3% 0 ACRS ACLARIS THERAPEUTICS INC More: the full row for ACLARIS THERAPEUTICS INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: not reported; 2018Q3: not reported; 2018Q4: 1,877,502 shares 1,877,502 $13.9M 2.86% new Timeline STRONGBRIDGE BIOPHARMA PLC STRONGBRIDGE BIOPHARMA PLC More: the full row for STRONGBRIDGE BIOPHARMA PLC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 2,793,752 shares; 2018Q2: 2,340,649 shares; 2018Q3: 2,563,096 shares; 2018Q4: 2,821,722 shares 2,821,722 $12.6M 2.61% +258,626 CPRX CATALYST PHARMACEUTICALS INC More: the full row for CATALYST PHARMACEUTICALS INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 6,812,764 shares; 2018Q2: 6,772,764 shares; 2018Q3: 5,136,264 shares; 2018Q4: 6,268,298 shares 6,268,298 $12M 2.48% +1,132,034 Timeline INCY INCYTE CORP More: the full row for INCYTE CORP Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: not reported; 2018Q3: not reported; 2018Q4: 183,300 shares 183,300 $11.7M 2.4% new Timeline NANOSTRING TECHNOLOGIES INC NANOSTRING TECHNOLOGIES INC More: the full row for NANOSTRING TECHNOLOGIES INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: not reported; 2018Q3: 850,000 shares; 2018Q4: 720,600 shares 720,600 $10.7M 2.2% -129,400 QUOTIENT LTD QUOTIENT LTD More: the full row for QUOTIENT LTD Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: 439,700 shares; 2018Q3: 804,700 shares; 2018Q4: 1,697,582 shares 1,697,582 $10.4M 2.14% +892,882 ADMA ADMA BIOLOGICS INC More: the full row for ADMA BIOLOGICS INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 720,529 shares; 2018Q2: 3,249,829 shares; 2018Q3: 4,463,829 shares; 2018Q4: 4,226,077 shares 4,226,077 $10.1M 2.08% -237,752 Timeline GLOBAL BLOOD THERAPEUTICS U… GLOBAL BLOOD THERAPEUTICS USD More: the full row for GLOBAL BLOOD THERAPEUTICS USD Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: 80,100 shares; 2018Q3: not reported; 2018Q4: 240,909 shares 240,909 $9.89M 2.04% new ANTARES PHARMA INC ANTARES PHARMA INC More: the full row for ANTARES PHARMA INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 4,673,247 shares; 2018Q2: 4,623,247 shares; 2018Q3: 4,623,247 shares; 2018Q4: 3,444,147 shares 3,444,147 $9.37M 1.93% -1,179,100 IART INTEGRA LIFESCIENCES HLDGS C More: the full row for INTEGRA LIFESCIENCES HLDGS C Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 298,424 shares; 2018Q2: 163,424 shares; 2018Q3: 196,572 shares; 2018Q4: 196,572 shares 196,572 $8.87M 1.83% 0 Timeline MIRATI THERAPEUTICS INC MIRATI THERAPEUTICS INC More: the full row for MIRATI THERAPEUTICS INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 1,443,948 shares; 2018Q2: 1,020,178 shares; 2018Q3: 357,672 shares; 2018Q4: 200,000 shares 200,000 $8.48M 1.75% -157,672 INTERSECT ENT INC INTERSECT ENT INC More: the full row for INTERSECT ENT INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: not reported; 2018Q3: 234,200 shares; 2018Q4: 287,900 shares 287,900 $8.11M 1.67% +53,700 AVADEL PHARMACEUTICALS, PLC AVADEL PHARMACEUTICALS, PLC More: the full row for AVADEL PHARMACEUTICALS, PLC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 2,624,663 shares; 2018Q2: 2,724,663 shares; 2018Q3: 2,792,773 shares; 2018Q4: 3,102,673 shares 3,102,673 $8.01M 1.65% +309,900 SIERRA ONCOLOGY INC SIERRA ONCOLOGY INC More: the full row for SIERRA ONCOLOGY INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: 2,106,589 shares; 2018Q3: 4,090,344 shares; 2018Q4: 4,880,327 shares 4,880,327 $6.44M 1.33% +789,983 ALEXION PHARMACEUTICALS INC ALEXION PHARMACEUTICALS INC More: the full row for ALEXION PHARMACEUTICALS INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: not reported; 2018Q3: not reported; 2018Q4: 58,700 shares 58,700 $5.71M 1.18% new STRATA SKIN SCIENCES INC STRATA SKIN SCIENCES INC More: the full row for STRATA SKIN SCIENCES INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 203,346 shares; 2018Q2: 2,943,819 shares; 2018Q3: 2,181,363 shares; 2018Q4: 2,171,363 shares 2,171,363 $5.65M 1.16% -10,000 VRAYQ VIEWRAY INC More: the full row for VIEWRAY INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: not reported; 2018Q3: 250,000 shares; 2018Q4: 866,500 shares 866,500 $5.26M 1.08% +616,500 Timeline SOL GEL TECHNOLOGIES SOL GEL TECHNOLOGIES More: the full row for SOL GEL TECHNOLOGIES Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 647,700 shares; 2018Q2: 647,700 shares; 2018Q3: 847,700 shares; 2018Q4: 847,700 shares 847,700 $5.1M 1.05% 0 BIOHAVEN PHARMACEUTICAL HOL… BIOHAVEN PHARMACEUTICAL HOLDIN More: the full row for BIOHAVEN PHARMACEUTICAL HOLDIN Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: not reported; 2018Q3: not reported; 2018Q4: 129,300 shares 129,300 $4.78M 0.99% new LIVN LIVANOVA PLC More: the full row for LIVANOVA PLC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: 72,100 shares; 2018Q3: 51,000 shares; 2018Q4: 51,000 shares 51,000 $4.67M 0.96% 0 Timeline OPTINOSE INC OPTINOSE INC More: the full row for OPTINOSE INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: not reported; 2018Q3: not reported; 2018Q4: 710,600 shares 710,600 $4.41M 0.91% new NEOS THERAPEUTICS INC NEOS THERAPEUTICS INC More: the full row for NEOS THERAPEUTICS INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: not reported; 2018Q3: not reported; 2018Q4: 2,618,819 shares 2,618,819 $4.32M 0.89% new RVLPQ RVL PHARMACEUTICALS PLC ORDINA More: the full row for RVL PHARMACEUTICALS PLC ORDINA Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: not reported; 2018Q3: not reported; 2018Q4: 528,571 shares 528,571 $4.1M 0.84% new Timeline TELIGENT INC NEW TELIGENT INC NEW More: the full row for TELIGENT INC NEW Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 1,690,794 shares; 2018Q2: 2,999,817 shares; 2018Q3: 3,052,852 shares; 2018Q4: 2,823,383 shares 2,823,383 $3.87M 0.8% -229,469 TNDM TANDEM DIABETES CARE INC More: the full row for TANDEM DIABETES CARE INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: 570,598 shares; 2018Q3: 573,079 shares; 2018Q4: 89,100 shares 89,100 $3.38M 0.7% -483,979 Timeline VCEL VERICEL CORP More: the full row for VERICEL CORP Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 658,900 shares; 2018Q2: not reported; 2018Q3: 132,600 shares; 2018Q4: 190,000 shares 190,000 $3.31M 0.68% +57,400 Timeline HRTX HERON THERAPEUTICS INC More: the full row for HERON THERAPEUTICS INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 1,581,416 shares; 2018Q2: 519,787 shares; 2018Q3: 291,213 shares; 2018Q4: 119,294 shares 119,294 $3.09M 0.64% -171,919 Timeline KALV KALVISTA PHARMACEUTICALS INC More: the full row for KALVISTA PHARMACEUTICALS INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: not reported; 2018Q3: 150,000 shares; 2018Q4: 143,129 shares 143,129 $2.83M 0.58% -6,871 Timeline DOVA PHARMACEUTICALS INC DOVA PHARMACEUTICALS INC More: the full row for DOVA PHARMACEUTICALS INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: not reported; 2018Q3: not reported; 2018Q4: 351,800 shares 351,800 $2.67M 0.55% new KALA BIO INC COM KALA BIO INC COM More: the full row for KALA BIO INC COM Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 681,239 shares; 2018Q2: 598,586 shares; 2018Q3: 346,083 shares; 2018Q4: 339,119 shares 339,119 $1.66M 0.34% -6,964 EIGER BIOPHARMACEUTICALS INC EIGER BIOPHARMACEUTICALS INC More: the full row for EIGER BIOPHARMACEUTICALS INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: not reported; 2018Q3: not reported; 2018Q4: 143,300 shares 143,300 $1.46M 0.3% new IDERA PHARMACEUTICALS INC IDERA PHARMACEUTICALS INC More: the full row for IDERA PHARMACEUTICALS INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: not reported; 2018Q3: 629,340 shares; 2018Q4: 486,604 shares 486,604 $1.35M 0.28% -142,736 NOVELION THERAPEUTICS INC NOVELION THERAPEUTICS INC More: the full row for NOVELION THERAPEUTICS INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: 1,948,554 shares; 2018Q2: 1,948,554 shares; 2018Q3: 1,948,554 shares; 2018Q4: 1,229,301 shares 1,229,301 $1.03M 0.21% -719,253 ATEC ALPHATEC HLDGS INC More: the full row for ALPHATEC HLDGS INC Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2017Q1: restricted; 2017Q2: restricted; 2017Q3: restricted; 2017Q4: restricted; 2018Q1: not reported; 2018Q2: 1,111,112 shares; 2018Q3: 669,812 shares; 2018Q4: 449,585 shares 449,585 $1.03M 0.21% -220,227 Timeline