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Blue Water Life Science Advisors, LP

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13F filer, CIK 1789778, LARKSPUR, CA

Blue Water Life Science Advisors, LP reported $159,327,918 across 9 holdings for the quarter ended 2025-12-31, in a 13F-HR filed 2026-02-17.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001420506-26-000497

Period
2025-12-31
Reported value
$159M
Holdings
9
Top 10 weight
100%
New
2
Sold out
0

Largest buys vs the previous quarter

SecurityShares changeApprox. value
TWSTnew+383,000$12.1M
GRALnew+99,000$8.47M
QTRXadded+1,134,400$7.21M
TEMadded+14,000$827K

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
ADPTreduced-380,000-$6.17M
GHreduced-50,600-$5.17M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q4 2025

Share positions as resolved from 13F-HR 0001420506-26-000497, largest first. % of portfolio is the value over $159,327,918, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
GHGUARDANT HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 451,047 shares; 2024Q4: 694,047 shares; 2025Q1: 694,047 shares; 2025Q2: 439,047 shares; 2025Q3: 405,647 shares; 2025Q4: 355,047 shares 355,047$36.3M22.76%-50,600Timeline
NTRANATERA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 291,094 shares; 2024Q4: 254,794 shares; 2025Q1: 208,494 shares; 2025Q2: 166,494 shares; 2025Q3: 141,494 shares; 2025Q4: 141,494 shares 141,494$32.4M20.34%0Timeline
ADPTADAPTIVE BIOTECHNOLOGIES CORQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,145,145 shares; 2024Q4: 2,145,145 shares; 2025Q1: 2,145,145 shares; 2025Q2: 2,145,145 shares; 2025Q3: 2,145,145 shares; 2025Q4: 1,765,145 shares 1,765,145$28.7M17.99%-380,000Timeline
PSNLPERSONALIS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,000,000 shares; 2024Q4: 1,132,900 shares; 2025Q1: 1,175,400 shares; 2025Q2: 1,676,300 shares; 2025Q3: 1,676,300 shares; 2025Q4: 1,676,300 shares 1,676,300$13.3M8.37%0Timeline
QTRXQUANTERIX CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 78,393 shares; 2024Q4: 78,393 shares; 2025Q1: 372,175 shares; 2025Q2: 957,747 shares; 2025Q3: 957,747 shares; 2025Q4: 2,092,147 shares 2,092,147$13.3M8.35%+1,134,400Timeline
TWSTTWIST BIOSCIENCE CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 383,000 shares 383,000$12.1M7.63%newTimeline
CDNACAREDX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 604,000 shares; 2024Q4: 604,000 shares; 2025Q1: 724,014 shares; 2025Q2: 724,014 shares; 2025Q3: 510,000 shares; 2025Q4: 510,000 shares 510,000$9.61M6.03%0Timeline
GRALGRAIL INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 99,000 shares 99,000$8.47M5.32%newTimeline
TEMTEMPUS AI INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 90,000 shares; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 72,412 shares; 2025Q4: 86,412 shares 86,412$5.1M3.2%+14,000Timeline

How Q4 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001420506-26-000497 base2026-02-17acceptance time not in the bulk data set