13F-HR filed by SABBY MANAGEMENT, LLC
SABBY MANAGEMENT, LLC filed this 13F-HR for the quarter ended 2016-12-31, filed 2017-02-14, with 293 holding rows worth $1,719,016,000.
- Accession
- 0001144204-17-008083
- Filer
- CIK 1535610
- Filed
- 2017-02-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2016
A holdings report, 293 entries on the cover page, a total value of $1,719,016,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $1,719,016,000 with VALUE read as thousands by filing date, 13F file number 028-15245. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerMintz Hal 028-13502
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| ELI LILLY & CO | 532457908 | CALL | 23,675 | $174,130,000 | thousands by filing date | call |
| SPDR S&P 500 ETF TR | 78462F953 | PUT | 6,000 | $134,118,000 | thousands by filing date | put |
| ISHARES TR | 464287955 | PUT | 7,419 | $100,045,000 | thousands by filing date | put |
| REGENERON PHARMACEUTICALS | 75886F957 | COM | 2,198 | $80,686,000 | thousands by filing date | put |
| MERCK & CO INC | 58933Y905 | CALL | 12,648 | $74,459,000 | thousands by filing date | call |
| REGENERON PHARMACEUTICALS COM | 75886F107 | Stock | 162,517 | $59,658,000 | thousands by filing date | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 2,014,787 | $55,266,000 | thousands by filing date | |
| AMGEN INC | 031162950 | COM | 3,694 | $54,010,000 | thousands by filing date | put |
| SAREPTA THERAPEUTICS INC | 803607950 | COM | 19,251 | $52,805,000 | thousands by filing date | put |
| BRISTOL-MYERS SQUIBB CO | 110122958 | COM | 8,478 | $49,545,000 | thousands by filing date | put |
| HCA HEALTHCARE INC | 40412C901 | CALL | 6,491 | $48,046,000 | thousands by filing date | call |
| Amgen Inc. | 031162100 | COM | 252,795 | $36,961,000 | thousands by filing date | |
| BRISTOL-MYERS SQUIBB CO | 110122908 | CALL | 5,419 | $31,669,000 | thousands by filing date | call |
| TEVA PHARMACEUTICAL INDS LTD | 881624909 | CALL | 8,638 | $31,313,000 | thousands by filing date | call |
| GILEAD SCIENCES INC | 375558903 | COM | 4,317 | $30,914,000 | thousands by filing date | call |
| ELI LILLY & CO | 532457958 | PUT | 4,043 | $29,736,000 | thousands by filing date | put |
| SPDR SERIES TRUST | 78464A950 | PUT | 4,623 | $27,364,000 | thousands by filing date | put |
| TESARO INC | 881569907 | CALL | 1,866 | $25,094,000 | thousands by filing date | call |
| EXPRESS SCRIPTS HOLDING CO | 30219G908 | COM | 2,897 | $19,928,000 | thousands by filing date | call |
| ALEXION PHARMACEUTICALS INC | 015351909 | COM | 1,586 | $19,405,000 | thousands by filing date | call |
| ACADIA PHARMACEUTICALS INC | 004225908 | COM | 6,470 | $18,659,000 | thousands by filing date | call |
| Bristol-Myers Squibb Company | 110122108 | COM | 289,183 | $16,900,000 | thousands by filing date | |
| MYLAN N V | N59465909 | CALL | 4,162 | $15,878,000 | thousands by filing date | call |
| UNITED THERAPEUTICS CORP DEL | 91307C952 | PUT | 1,100 | $15,777,000 | thousands by filing date | put |
| Eli Lilly and Company | 532457108 | COM | 213,113 | $15,674,000 | thousands by filing date | |
| ZOGENIX INC | 98978L904 | CALL | 12,366 | $15,025,000 | thousands by filing date | call |
| CLOVIS ONCOLOGY INC | 189464900 | CALL | 3,378 | $15,005,000 | thousands by filing date | call |
| ABBVIE INC | 00287Y909 | CALL | 2,204 | $13,801,000 | thousands by filing date | call |
| ASTRAZENECA PLC | 004635308 | ADR | 4,753 | $12,985,000 | thousands by filing date | call |
| ACORDA THERAPEUTICS ORD | 00484M956 | Cmn | 6,145 | $11,553,000 | thousands by filing date | put |
| HORIZON PHARMA PLC | G4617B905 | CALL | 5,962 | $9,647,000 | thousands by filing date | call |
| ALKERMES PLC | G01767905 | SHS | 1,639 | $9,110,000 | thousands by filing date | call |
| RETROPHIN INC | 761299906 | CALL | 4,798 | $9,083,000 | thousands by filing date | call |
| EXPRESS SCRIPTS HOLDING CO | 30219G958 | COM | 1,191 | $8,193,000 | thousands by filing date | put |
| EXELIXIS INC | 30161Q954 | COM | 5,392 | $8,039,000 | thousands by filing date | put |
| VERTEX PHARMACEUTICALS INC | 92532F900 | CALL | 1,070 | $7,883,000 | thousands by filing date | call |
| ALNYLAM PHARMACEUTICALS INC | 02043Q957 | COM | 2,056 | $7,698,000 | thousands by filing date | put |
| TESARO INC | 881569957 | PUT | 563 | $7,571,000 | thousands by filing date | put |
| REGENERON PHARMACEUTICALS | 75886F907 | CALL | 202 | $7,415,000 | thousands by filing date | call |
| ABBVIE INC | 00287Y959 | COM | 1,178 | $7,377,000 | thousands by filing date | put |
| AXOVANT SCIENCES LTD | G0750W904 | CALL | 5,726 | $7,112,000 | thousands by filing date | call |
| ONCOBIOLOGICS INC | 68235M105 | COM | 2,238,470 | $6,738,000 | thousands by filing date | |
| PUMA BIOTECHNOLOGY INC | 74587V907 | COM | 2,177 | $6,683,000 | thousands by filing date | call |
| PTC THERAPEUTICS INC | 69366J900 | COM | 5,940 | $6,481,000 | thousands by filing date | call |
| HUMANA INC | 444859902 | COM | 291 | $5,937,000 | thousands by filing date | call |
| BIOGEN INC COM | 09062X103 | Stock | 20,000 | $5,672,000 | thousands by filing date | |
| HESS CORP | 42809H907 | COM | 902 | $5,619,000 | thousands by filing date | call |
| KITE PHARMA INC | 49803L909 | COM | 1,171 | $5,251,000 | thousands by filing date | call |
| PUMA BIOTECHNOLOGY INC | 74587V957 | PUT | 1,699 | $5,216,000 | thousands by filing date | put |
| MOTIF BIO PLC | 619784101 | SPONSORED ADR | 847,826 | $5,121,000 | thousands by filing date | |
| AMICUS THERAPEUTIC | 03152W909 | CALL | 10,216 | $5,077,000 | thousands by filing date | call |
| IONIS PHARMACEUTICALS INC | 462222900 | CALL | 1,054 | $5,041,000 | thousands by filing date | call |
| ACORDA THERAPEUTICS INC | 00484M106 | COM | 263,947 | $4,962,000 | thousands by filing date | |
| ALNYLAM PHARMACEUTICALS INC | 02043Q907 | CALL | 1,240 | $4,643,000 | thousands by filing date | call |
| SYNERGY PHARMACEUTICALS DEL | 871639908 | CALL | 7,536 | $4,589,000 | thousands by filing date | call |
| RADIUS HEALTH INC | 750469957 | PUT | 1,190 | $4,526,000 | thousands by filing date | put |
| HORIZON PHARMA PLC | G4617B955 | PUT | 2,791 | $4,516,000 | thousands by filing date | put |
| NEUROCRINE BIOSCIENCES INC | 64125C909 | COM | 1,153 | $4,462,000 | thousands by filing date | call |
| AMGEN INC | 031162900 | CALL | 301 | $4,401,000 | thousands by filing date | call |
| SAGE THERAPEUTICS INC | 78667J908 | COM | 849 | $4,335,000 | thousands by filing date | call |
| ACHILLION PHARMACEUTICALS IN | 00448Q901 | Cmn | 10,087 | $4,166,000 | thousands by filing date | call |
| PORTOLA PHARMACEUTICALS INC | 737010908 | COM | 1,803 | $4,046,000 | thousands by filing date | call |
| MEDICINES COMPANY | 584688955 | COM | 1,172 | $3,978,000 | thousands by filing date | put |
| APPLIED DNA SCIENCES INC | 03815U201 | COM NEW | 2,109,601 | $3,903,000 | thousands by filing date | |
| STEMLINE THERAPEUTICS INC | 85858C107 | COM | 357,806 | $3,829,000 | thousands by filing date | |
| MEDICINES CO | 584688105 | COM | 112,392 | $3,815,000 | thousands by filing date | |
| AMARIN CORPORATION PLC -ADR | 023111906 | ADR | 12,346 | $3,803,000 | thousands by filing date | call |
| UNITED THERAPEUTICS CORP DEL | 91307C902 | OPTION | 263 | $3,772,000 | thousands by filing date | call |
| LA JOLLA PHARMACEUTICAL CO | 503459604 | COM PAR $.0001 2 | 210,978 | $3,698,000 | thousands by filing date | |
| BLUEBIRD BIO INC | 09609G900 | COM | 597 | $3,665,000 | thousands by filing date | call |
| IONIS PHARMACEUTICALS INC | 462222950 | COM | 737 | $3,525,000 | thousands by filing date | put |
| MONSANTO CO | 61166W901 | COM | 313 | $3,293,000 | thousands by filing date | call |
| AXOVANT SCIENCES LTD | G0750W954 | PUT | 2,638 | $3,276,000 | thousands by filing date | put |
| BIOGEN INC | 09062X903 | CALL | 115 | $3,261,000 | thousands by filing date | call |
| PUMA BIOTECHNOLOGY INC | 74587V107 | COMMON STOCK | 103,243 | $3,170,000 | thousands by filing date | |
| CIDARA THERAPEUTICS INC COM NEW | 171757107 | Stock | 292,398 | $3,041,000 | thousands by filing date | |
| TENAX THERAPEUTICS INC | 88032L100 | COM | 1,516,835 | $2,958,000 | thousands by filing date | |
| LA JOLLA PHARMACEUTICAL CO | 503459904 | CALL | 1,687 | $2,957,000 | thousands by filing date | call |
| INTEC PHARMA LTD JERUSALEM | M53644106 | SHS | 514,100 | $2,930,000 | thousands by filing date | |
| BIOGEN INC | 09062X953 | COM | 100 | $2,836,000 | thousands by filing date | put |
| EIGER BIOPHARMACEUTICALS INC | 28249U105 | COM | 240,541 | $2,802,000 | thousands by filing date | |
| INTRA CELLULAR THERAPIES INC | 46116X901 | CALL | 1,781 | $2,688,000 | thousands by filing date | call |
| HALOZYME THERAPEUTICS INC | 40637H909 | COM | 2,708 | $2,676,000 | thousands by filing date | call |
| EXELIXIS INC | 30161Q904 | COM | 1,783 | $2,658,000 | thousands by filing date | call |
| GW PHARMACEUTICALS PLC | 36197T903 | CALL | 234 | $2,615,000 | thousands by filing date | call |
| COHERUS ONCOLOGY INC | 19249H953 | PUT | 912 | $2,567,000 | thousands by filing date | put |
| FIBROGEN INC | 31572Q908 | CALL | 1,189 | $2,544,000 | thousands by filing date | call |
| INSMED INC | 457669957 | COM PAR $.01 | 1,913 | $2,531,000 | thousands by filing date | put |
| CYTORI THERAPEUTICS INC | 23283K204 | COM NEW | 1,651,835 | $2,494,000 | thousands by filing date | |
| PROTHENA CORP PLC | G72800908 | SHS | 490 | $2,410,000 | thousands by filing date | call |
| TENAX THERAPEUTICS INC | 88032L900 | COM | 12,237 | $2,386,000 | thousands by filing date | call |
| SYNTHETIC BIOLOGICS INC | 87164U102 | COM | 3,031,953 | $2,312,000 | thousands by filing date | |
| AGIOS PHARMACEUTICALS INC | 00847X904 | COM | 545 | $2,274,000 | thousands by filing date | call |
| PACIRA BIOSCIENCES INC | 695127900 | COM | 700 | $2,261,000 | thousands by filing date | call |
| VERTEX PHARMACEUTICALS INC | 92532F950 | COM | 296 | $2,181,000 | thousands by filing date | put |
| ENDO INTL PLC | G30401956 | PUT | 1,323 | $2,179,000 | thousands by filing date | put |
| LEXICON PHARMACEUTICALS INC | 528872902 | COM NEW | 1,563 | $2,162,000 | thousands by filing date | call |
| GW PHARMACEUTICALS PLC | 36197T953 | PUT | 192 | $2,146,000 | thousands by filing date | put |
| OPKO HEALTH INC | 68375N953 | COM | 2,275 | $2,116,000 | thousands by filing date | put |
| ENDO INTL PLC | G30401106 | SHS | 126,139 | $2,078,000 | thousands by filing date | |
| SIENTRA INC | 82621J955 | PUT | 2,413 | $2,056,000 | thousands by filing date | put |
| DURECT CORP | 266605104 | COM | 1,528,516 | $2,048,000 | thousands by filing date | |
| REDHILL BIOPHARMA LTD | 757468103 | ADR | 191,785 | $2,006,000 | thousands by filing date | |
| Arbutus Biopharma Corp | 03879J100 | Common Shares, without par value | 792,617 | $1,942,000 | thousands by filing date | |
| INSMED INC | 457669907 | CALL | 1,459 | $1,930,000 | thousands by filing date | call |
| SANGAMO THERAPEUTICS INC | 800677906 | CALL | 6,177 | $1,884,000 | thousands by filing date | call |
| EDITAS MEDICINE INC | 28106W103 | COM | 115,000 | $1,866,000 | thousands by filing date | |
| CLOVIS ONCOLOGY INC | 189464950 | PUT | 420 | $1,866,000 | thousands by filing date | put |
| PIERIS PHARMACEUTICALS INC | 720795103 | COM | 1,296,034 | $1,814,000 | thousands by filing date | |
| OPKO HEALTH INC | 68375N103 | COM | 190,955 | $1,776,000 | thousands by filing date | |
| WAFERGEN BIO-SYSTEMS INC | 93041P506 | COM PAR NEW | 358,535 | $1,771,000 | thousands by filing date | |
| CYTRX CORP | 232828509 | COM PAR $.001 | 4,697,802 | $1,749,000 | thousands by filing date | |
| BARCLAYS BK PLC | 06740Q260 | IPATH S&P MT ETN | 50,000 | $1,743,000 | thousands by filing date | |
| OHR PHARMACEUTICAL INC | 67778H200 | COMMON STOCK | 1,156,393 | $1,735,000 | thousands by filing date | |
| INTELLIA THERAPEUTICS INC | 45826J105 | COM | 130,000 | $1,704,000 | thousands by filing date | |
| PARATEK PHARMACEUTICALS INC | 699374302 | Equity | 110,000 | $1,694,000 | thousands by filing date | |
| SAREPTA THERAPEUTICS INC | 803607900 | COM | 611 | $1,676,000 | thousands by filing date | call |
| NEWLINK GENETICS CORP | 651511907 | COM | 1,580 | $1,624,000 | thousands by filing date | call |
| EXPRESS SCRIPTS HLDG CO | 30219G108 | COM | 23,494 | $1,616,000 | thousands by filing date | |
| ACADIA PHARMACEUTICALS INC | 004225958 | COM | 548 | $1,580,000 | thousands by filing date | put |
| Ocugen | 43358V109 | Common | 944,891 | $1,578,000 | thousands by filing date | |
| Lion Biotechnologies | 53619R102 | COM | 226,081 | $1,571,000 | thousands by filing date | |
| FORWARD PHARMA A/S | 34986J105 | SPONSORED ADR | 104,273 | $1,565,000 | thousands by filing date | |
| MEDICINES COMPANY | 584688905 | COM | 457 | $1,551,000 | thousands by filing date | call |
| ROKA BIOSCIENCE INC COM NEW | 775431208 | Stock | 365,220 | $1,549,000 | thousands by filing date | |
| VERACYTE INC COM | 92337F107 | Stock | 193,999 | $1,502,000 | thousands by filing date | |
| ONCOSEC MED INC | 68234L207 | COM NEW | 1,173,946 | $1,444,000 | thousands by filing date | |
| AETERNA ZENTARIS INC | 007975402 | COM | 400,560 | $1,442,000 | thousands by filing date | |
| Sierra Oncology, Inc. | 74346L101 | common | 940,841 | $1,402,000 | thousands by filing date | |
| SOPHIRIS BIO INC F | 83578Q209 | FOREIGN CANADIAN | 496,729 | $1,391,000 | thousands by filing date | |
| OPKO HEALTH INC | 68375N903 | COM | 1,491 | $1,387,000 | thousands by filing date | call |
| CHECK CAP LTD | M2361E112 | SHS | 575,113 | $1,352,000 | thousands by filing date | |
| KITE PHARMA INC | 49803L959 | COM | 291 | $1,305,000 | thousands by filing date | put |
| AXOVANT SCIENCES LTD | G0750W104 | COM | 100,998 | $1,254,000 | thousands by filing date | |
| BIODELIVERY SCIENCES INTL IN | 09060J106 | COM | 698,235 | $1,222,000 | thousands by filing date | |
| CARDIOME PHARMA CORP | 14159U301 | COM NO PAR | 437,720 | $1,208,000 | thousands by filing date | |
| NEVRO CORP | 64157F903 | CALL | 165 | $1,199,000 | thousands by filing date | call |
| GENETIC TECHNOLOGIES LTD | 37185R208 | SPONSORED ADR | 1,070,333 | $1,156,000 | thousands by filing date | |
| APPLIED DNA SCIENCES INC | 03815U110 | *W EXP 11/21/201 | 2,277,612 | $1,139,000 | thousands by filing date | |
| REXAHN PHARMACEUTICALS INC | 761640101 | COM | 7,326,681 | $1,040,000 | thousands by filing date | |
| IGNYTA INC | 451731103 | COM | 195,000 | $1,034,000 | thousands by filing date | |
| AGENUS INC | 00847G955 | COM NEW | 2,503 | $1,031,000 | thousands by filing date | put |
| ONCONOVA THERAPEUTICS INC COM PAR | 68232V306 | Stock | 452,804 | $1,028,000 | thousands by filing date | |
| SUCAMPO PHARMACEUTICALS-CL A | 864909106 | CL A | 75,000 | $1,016,000 | thousands by filing date | |
| CAPRICOR THERAPEUTICS INC | 14070B101 | COM | 372,046 | $990,000 | thousands by filing date | |
| ZAFGEN INC | 98885E103 | COM | 310,000 | $986,000 | thousands by filing date | |
| FOAMIX PHARMACEUTICALS LTD | M46135905 | CALL | 881 | $978,000 | thousands by filing date | call |
| LEXICON PHARMACEUTICALS INC | 528872302 | COMMON STOCK | 70,040 | $969,000 | thousands by filing date | |
| HEMISPHERX BIOPHARMA INC | 42366C301 | COM NEW | 1,391,286 | $960,000 | thousands by filing date | |
| DURECT CORP | 266605904 | CALL | 6,927 | $928,000 | thousands by filing date | call |
| Rocket Pharmaceuticals Inc | 45780V102 | SHS | 150,930 | $921,000 | thousands by filing date | |
| RICEBRAN TECHNOLOGIES | 762831204 | COM NEW | 875,286 | $902,000 | thousands by filing date | |
| REGENXBIO INC | 75901B107 | COM | 48,400 | $898,000 | thousands by filing date | |
| BIO PATH HOLDINGS INC | 09057N102 | COM | 664,046 | $896,000 | thousands by filing date | |
| LION BIOTECHNOLOGIES INC | 53619R952 | PUT | 1,260 | $876,000 | thousands by filing date | put |
| CYTORI THERAPEUTICS INC | 23283K121 | *W EXP 12/09/201 | 1,273,712 | $866,000 | thousands by filing date | |
| PALATIN TECHNOLOGIES INC | 696077403 | COM PAR $ .01 | 1,672,573 | $853,000 | thousands by filing date | |
| Adverum Biotechnologies, Inc. | 00773U108 | Common Stock | 283,306 | $822,000 | thousands by filing date | |
| COHERUS ONCOLOGY INC | 19249H103 | COM | 28,618 | $806,000 | thousands by filing date | |
| VANDA PHARMACEUTICALS INC | 921659908 | COM | 503 | $802,000 | thousands by filing date | call |
| SUNESIS PHARMACEUTICALS INC | 867328700 | COM | 221,326 | $801,000 | thousands by filing date | |
| DYNAVAX TECHNOLOGIES CORP | 268158901 | COM NEW | 1,979 | $782,000 | thousands by filing date | call |
| RETROPHIN INC | 761299956 | PUT | 408 | $772,000 | thousands by filing date | put |
| ACTINIUM PHARMACEUTICALS INC | 00507W107 | COM | 868,608 | $760,000 | thousands by filing date | |
| ACORDA THERAPEUTICS ORD | 00484M906 | Cmn | 398 | $748,000 | thousands by filing date | call |
| HCA HEALTHCARE INC | 40412C951 | PUT | 100 | $740,000 | thousands by filing date | put |
| INSPIREMD INC | 45779A127 | *W EXP 07/07/202 | 1,210,106 | $726,000 | thousands by filing date | |
| ONCOBIOLOGICS INC | 68235M121 | *W EXP 05/18/201 | 930,272 | $726,000 | thousands by filing date | |
| AEVI GENOMIC MEDICINE INC | 00835P105 | COM | 138,195 | $716,000 | thousands by filing date | |
| SPDR SER TR | 78464A870 | S&P BIOTECH | 11,700 | $693,000 | thousands by filing date | |
| OCERA THERAPEUTICS INC COM | 67552A108 | COM | 328,632 | $690,000 | thousands by filing date | |
| BIOBLAST PHARMA LTD | M20156101 | SHS | 660,157 | $687,000 | thousands by filing date | |
| AMPLIPHI BIOSCIENCES ORD SHS | 03211P202 | COM | 1,518,814 | $668,000 | thousands by filing date | |
| VISTAGEN THERAPEUTICS INC | 92840H202 | COM | 176,384 | $658,000 | thousands by filing date | |
| PTC THERAPEUTICS INC | 69366J950 | PUT | 597 | $651,000 | thousands by filing date | put |
| ALCOBRA LTD | M2239P909 | SHS | 3,102 | $651,000 | thousands by filing date | call |
| Alliqua BioMedical Inc | 019621200 | COM NEW | 1,100,398 | $649,000 | thousands by filing date | |
| FOAMIX PHARMACEUTICALS LTD | M46135105 | SHS | 58,338 | $648,000 | thousands by filing date | |
| CHAMPIONS ONCOLOGY INC | 15870P307 | COM NEW | 253,504 | $641,000 | thousands by filing date | |
| VTV THERAPEUTICS INC CL A | 918385105 | Stock | 132,547 | $640,000 | thousands by filing date | |
| BRAINSTORM CELL THERAPEUTICS | 10501E201 | COM | 250,766 | $637,000 | thousands by filing date | |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 48,043 | $636,000 | thousands by filing date | |
| SIENTRA INC | 82621J105 | COM | 70,973 | $605,000 | thousands by filing date | |
| OPGEN INC | 68373L109 | COM | 525,146 | $604,000 | thousands by filing date | |
| LA JOLLA PHARMACEUTICAL CO | 503459954 | PUT | 336 | $589,000 | thousands by filing date | put |
| NEWLINK GENETICS CORP | 651511107 | COM | 56,289 | $579,000 | thousands by filing date | |
| AMICUS THERAPEUTIC | 03152W959 | PUT | 1,140 | $567,000 | thousands by filing date | put |
| AZURRX BIOPHARMA INC | 05502L105 | COM | 118,993 | $564,000 | thousands by filing date | |
| MOTIF BIO PLC | 619784119 | *W EXP 11/09/202 | 426,170 | $550,000 | thousands by filing date | |
| SUPERCONDUCTOR TECHNOLOGIES | 867931503 | COM PAR NEW | 434,747 | $535,000 | thousands by filing date | |
| BLUEPRINT MEDICINES CORP | 09627Y959 | COM | 190 | $533,000 | thousands by filing date | put |
| HALOZYME THERAPEUTICS INC | 40637H959 | COM | 532 | $526,000 | thousands by filing date | put |
| SAGE THERAPEUTICS INC | 78667J958 | COM | 102 | $521,000 | thousands by filing date | put |
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 13,823 | $518,000 | thousands by filing date | |
| PACIRA BIOSCIENCES INC | 695127950 | PUT | 159 | $514,000 | thousands by filing date | put |
| NEURODERM LTD | M74231107 | ORD SHS | 23,033 | $511,000 | thousands by filing date | |
| MANNKIND CORP COMMON STOCK | 56400P951 | Cmn | 7,842 | $499,000 | thousands by filing date | put |
| ARBUTUS BIOPHARMA CORP | 03879J900 | COM | 2,033 | $498,000 | thousands by filing date | call |
| MIRATI THERAPEUTICS INC | 60468T105 | COM | 99,735 | $474,000 | thousands by filing date | |
| FLEXION THERAPEUTICS INC | 33938J956 | PUT | 248 | $472,000 | thousands by filing date | put |
| STRATA SKIN SCIENCES INC | 86272A107 | COM | 1,034,820 | $455,000 | thousands by filing date | |
| RXI PHARMACEUTICALS CORP | 74979C113 | *W | 2,270,283 | $454,000 | thousands by filing date | |
| VERICEL CORP | 92346J108 | COM | 149,900 | $450,000 | thousands by filing date | |
| XTL BIOPHARMACEUTICALS-ADR | 98386D208 | COM | 724,134 | $434,000 | thousands by filing date | |
| ONCONOVA THERAPEUTICS INC | 68232V116 | *W EXP 07/11/202 | 691,072 | $428,000 | thousands by filing date | |
| CEL SCI CORP | 150837508 | COM PAR $0.01 | 6,360,207 | $427,000 | thousands by filing date | |
| OPHTHOTECH CORP | 683745903 | CALL | 883 | $426,000 | thousands by filing date | call |
| CELSION CORPORATION COM PAR | 15117N404 | Stock | 1,333,093 | $416,000 | thousands by filing date | |
| WINDTREE THERAPEUTICS INC | 97382D105 | COM | 334,414 | $415,000 | thousands by filing date | |
| BELLEROPHON THERAPEUTICS INC | 078771102 | COM | 789,857 | $414,000 | thousands by filing date | |
| THERAPEUTICSMD INC | 88338N907 | COM | 703 | $406,000 | thousands by filing date | call |
| CELLECTAR BIOSCIENCES INC | 15117F302 | COM | 323,515 | $395,000 | thousands by filing date | |
| TG THERAPEUTICS INC | 88322Q958 | COM | 848 | $394,000 | thousands by filing date | put |
| BENITEC BIOPHARMA LTD | 082053307 | SPONS ADR NEW | 254,445 | $389,000 | thousands by filing date | |
| GENVEC INC | 37246C406 | COM PAR | 120,544 | $387,000 | thousands by filing date | |
| DEXTERA SURGICAL INC COM | 252366109 | CS | 397,863 | $382,000 | thousands by filing date | |
| STEMLINE THERAPEUTICS INC | 85858C907 | CALL | 356 | $381,000 | thousands by filing date | call |
| CHIMERIX INC COM | 16934W106 | Stock | 79,900 | $368,000 | thousands by filing date | |
| COMBIMATRIX CORPORATION | 20009T147 | *W EXP 03/18/202 | 844,917 | $363,000 | thousands by filing date | |
| PSIVIDA CORP | 74440J101 | COM | 205,100 | $351,000 | thousands by filing date | |
| AMARIN CORPORATION PLC -ADR | 023111956 | ADR | 1,118 | $344,000 | thousands by filing date | put |
| THERAPEUTICSMD INC | 88338N957 | COM | 586 | $338,000 | thousands by filing date | put |
| DEPOMED INC CMN STOCK | 249908904 | Cmn | 186 | $335,000 | thousands by filing date | call |
| IMMUNOCELLULAR THERAPEUTICS | 452536204 | COM NEW | 160,129 | $328,000 | thousands by filing date | |
| BIOCEPT INC | 09072V204 | COM NEW | 411,432 | $319,000 | thousands by filing date | |
| EYEGATE PHARMACEUTICALS INC | 30233M107 | COM | 192,721 | $314,000 | thousands by filing date | |
| INOTEK PHARMACEUTICALS CORP | 45780V952 | COM | 500 | $305,000 | thousands by filing date | put |
| AMICUS THERAPEUTICS INC | 03152W109 | COM | 60,309 | $300,000 | thousands by filing date | |
| ADVAXIS INC | 007624958 | PUT | 414 | $296,000 | thousands by filing date | put |
| DICERNA PHARMACEUTICALS INC | 253031108 | COM | 100,000 | $288,000 | thousands by filing date | |
| RXI PHARMACEUTICALS CORP NEW | 74979C501 | COM | 397,371 | $284,000 | thousands by filing date | |
| BIOPHARMX CORP | 09072X101 | COM | 708,046 | $265,000 | thousands by filing date | |
| DYNAVAX TECHNOLOGIES CORP | 268158201 | COM NEW | 66,091 | $261,000 | thousands by filing date | |
| ROSETTA GENOMICS LTD | M82183126 | SHS NEW NIS 0.6 | 591,339 | $248,000 | thousands by filing date | |
| FLEXION THERAPEUTICS INC | 33938J906 | CALL | 126 | $240,000 | thousands by filing date | call |
| PORTOLA PHARMACEUTICALS INC | 737010958 | PUT | 107 | $240,000 | thousands by filing date | put |
| AETERNA ZENTARIS INC | 007975952 | COM | 614 | $221,000 | thousands by filing date | put |
| NEUROMETRIX INC | 641255153 | *W | 3,017,747 | $211,000 | thousands by filing date | |
| FLEXION THERAPEUTICS INC | 33938J106 | COM | 10,914 | $208,000 | thousands by filing date | |
| PROQR THERAPEUTICS NV | N71542109 | SHS EURO | 40,000 | $196,000 | thousands by filing date | |
| JUNO THERAPEUTICS INC COM | 48205A909 | Option | 103 | $194,000 | thousands by filing date | call |
| SANGAMO THERAPEUTICS INC | 800677106 | COM | 63,204 | $193,000 | thousands by filing date | |
| Alcobra Ltd | M2239P109 | SHS | 91,858 | $193,000 | thousands by filing date | |
| ADVAXIS INC | 007624908 | CALL | 270 | $193,000 | thousands by filing date | call |
| IMMUNOCELLULAR THERAPEUTICS | 452536121 | *W EXP 08/12/202 | 383,471 | $192,000 | thousands by filing date | |
| HERON THERAPEUTICS INC | 427746902 | COM | 141 | $185,000 | thousands by filing date | call |
| IMMUNOMEDICS INC | 452907108 | COM | 50,000 | $184,000 | thousands by filing date | |
| SYNLOGIC | 60470J103 | Stock | 100,200 | $180,000 | thousands by filing date | |
| CELLECT BIOTECHNOLOGY LTD | 15116C102 | SPON ADS | 57,348 | $177,000 | thousands by filing date | |
| LEXICON PHARMACEUTICALS INC | 528872952 | COM NEW | 121 | $167,000 | thousands by filing date | put |
| RENNOVA HEALTH INC COM | 759757107 | Stock | 2,022,213 | $167,000 | thousands by filing date | |
| ZOGENIX INC | 98978L954 | PUT | 136 | $165,000 | thousands by filing date | put |
| GALENA BIOPHARMA INC | 363256954 | COM NEW | 847 | $164,000 | thousands by filing date | put |
| OTONOMY INC | 68906L105 | COM | 10,000 | $159,000 | thousands by filing date | |
| ONCOBIOLOG-CW17A | 68235M113 | EQUITY WRT | 930,592 | $154,000 | thousands by filing date | |
| Capnia, Inc. | 14066L105 | Common | 179,002 | $145,000 | thousands by filing date | |
| THERAPEUTICSMD INC | 88338N107 | COM | 24,955 | $144,000 | thousands by filing date | |
| PARNELL PHARMACEUT HLDGS LIMITED SHS | Q73622104 | Foreign Ordinary Shares | 200,549 | $138,000 | thousands by filing date | |
| LION BIOTECHNOLOGIES INC | 53619R990 | COM | 195 | $136,000 | thousands by filing date | call |
| NEKTAR THERAPEUTICS CMN STK | 640268908 | Cmn | 110 | $135,000 | thousands by filing date | call |
| NEUROMETRIX INC | 641255500 | COM PAR NEW | 166,268 | $123,000 | thousands by filing date | |
| CEMPRA INC | 15130J109 | COM | 43,121 | $121,000 | thousands by filing date | |
| AKARI THERAPEUTICS PLC | 00972G108 | ADR | 17,428 | $120,000 | thousands by filing date | |
| RENNOVA HEALTH INC | 759757123 | *W EXP 06/30/202 | 4,926,013 | $118,000 | thousands by filing date | |
| ALCOBRA LTD | M2239P959 | SHS | 559 | $117,000 | thousands by filing date | put |
| EDAP TMS S A | 268311957 | SPONSORED ADR | 341 | $112,000 | thousands by filing date | put |
| DYNAVAX TECHNOLOGIES CORP | 268158951 | COM NEW | 258 | $102,000 | thousands by filing date | put |
| CANCER GENETICS INC. | 13739u104 | COM | 71,971 | $97,000 | thousands by filing date | |
| ASTERIAS BIOTHERAPEUTICS INC | 04624N907 | CALL | 200 | $92,000 | thousands by filing date | call |
| NIVALIS THERAPEUTICS INC | 65481J109 | COM | 40,004 | $90,000 | thousands by filing date | |
| CELLECTAR BIOSCIENCES INC | 15117F120 | *W EXP 08/20/201 | 201,889 | $85,000 | thousands by filing date | |
| Adobe Systems Inc | 98979H103 | COM | 103,600 | $81,000 | thousands by filing date | |
| ACURA PHARMACEUTICALS INC COM | 00509L802 | COM | 103,444 | $79,000 | thousands by filing date | |
| EDAP TMS S A | 268311107 | SPONSORED ADR | 22,993 | $76,000 | thousands by filing date | |
| ADVAXIS INC | 007624208 | COM NEW | 10,443 | $75,000 | thousands by filing date | |
| OVASCIENCE INC | 69014Q101 | COM | 48,450 | $74,000 | thousands by filing date | |
| RESHAPE LIFESCIENCES INC NEW | 29365M505 | Common Stock | 33,387 | $67,000 | thousands by filing date | |
| ATHERSYS INC | 04744L106 | COM | 43,263 | $66,000 | thousands by filing date | |
| INOTEK PHARMACEUTICALS CORP | 45780V902 | COM | 106 | $65,000 | thousands by filing date | call |
| ANTHERA PHARMACEUTICALS INC | 03674U901 | COM NEW | 987 | $64,000 | thousands by filing date | call |
| NEURALSTEM INC | 64127R302 | COM | 229,521 | $63,000 | thousands by filing date | |
| ANTHERA PHARMACEUTCLS INC | 03674U201 | Common equity shares | 91,055 | $59,000 | thousands by filing date | |
| MEDIGUS LTD | 58471G102 | SPONSORED ADR | 87,876 | $50,000 | thousands by filing date | |
| GREAT PANTHER RESOURCES LTD COMMON STOCK | 39115V951 | Cmn | 269 | $45,000 | thousands by filing date | put |
| GALENA BIOPHARMA INC COM NEW | 363256504 | Stock | 23,298 | $45,000 | thousands by filing date | |
| ADAMIS PHARMACEUTICALS CORP | 00547W958 | PUT | 134 | $42,000 | thousands by filing date | put |
| VIKING THERAPEUTICS INC | 92686J114 | *W EXP 04/13/202 | 86,349 | $39,000 | thousands by filing date | |
| TENAX THERAPEUTICS INC | 88032L950 | PUT | 169 | $33,000 | thousands by filing date | put |
| RIGEL PHARMACEUTICALS INC | 766559603 | COMMON STOCK | 12,350 | $29,000 | thousands by filing date | |
| GALECTIN THERAPEUTICS INC | 363225952 | COM NEW | 235 | $23,000 | thousands by filing date | put |
| NOVAVAX INC CMN STOCK | 670002904 | Cmn | 159 | $20,000 | thousands by filing date | call |
| BENITEC BIOPHARMA LTD | 082053117 | *W EXP 08/14/202 | 98,146 | $10,000 | thousands by filing date | |
| EYEGATE PHARMACEUTICALS INC | 30233M115 | *W EXP 08/05/202 | 20,604 | $6,000 | thousands by filing date |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001144204-17-008083 | this filing | 2017-02-14 | acceptance time not in the bulk data set |