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13F-HR filed by DEERFIELD MANAGEMENT COMPANY, L.P.

DEERFIELD MANAGEMENT COMPANY, L.P. filed this 13F-HR for the quarter ended 2015-12-31, filed 2016-02-16, with 109 holding rows worth $2,467,380,000.

Accession
0001140361-16-053179
Filed
2016-02-16
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2015

A holdings report, 109 entries on the cover page, a total value of $2,467,380,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $2,467,381,000 with VALUE read as thousands by filing date, 13F file number 028-05366. The quarter's positions are built on this report. The resolved quarter.

Other managers

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
HORIZON PHARMA PLCG4617B105SHS11,684,801$253,210,000thousands by filing date
NXSTAGE MEDICAL INC67072V103COMMON STOCK4,589,000$100,545,000thousands by filing date
DYAX CORP26746E103COM2,242,073$84,347,000thousands by filing date
ADEPTUS HEALTH006855100Common Stock1,307,908$71,307,000thousands by filing date
GLAXOSMITHKLINE PLC-ADR37733W105SPONSORED ADR1,675,385$67,602,000thousands by filing date
AETNA INC NEW00817Y108COM591,465$63,949,000thousands by filing date
DAVITA INC COM23918K108Stock822,000$57,302,000thousands by filing date
MYLAN NVN59465109SHS EURO1,056,000$57,098,000thousands by filing date
VANDA PHARMACEUTICALS INC921659108COM5,996,691$55,829,000thousands by filing date
Gilead Sciences,Inc.375558103COM532,000$53,833,000thousands by filing datecall
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS881624209ADR815,000$53,497,000thousands by filing date
FLAMEL TECHNOLOGIES-SP ADR338488109SPON4,072,809$49,729,000thousands by filing date
HWAY 1.5 7/18422245AB6Bond 30/360P2 U51,925,000$49,087,000thousands by filing dateprincipal
ARRAY BIOPHARMA INC04269XAA3NOTE 3.000% 6/045,000,000$42,292,000thousands by filing dateprincipal
GLOBAL BLOOD THERAPEUTICS USD37890U108COM1,163,811$37,626,000thousands by filing date
HEARTWARE INTERNATIONAL422368AA8NOTE39,226,000$37,364,000thousands by filing dateprincipal
ARRAY BIOPHARMA INC COM04269X105Stock8,729,361$36,838,000thousands by filing date
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS881624209ADR550,000$36,102,000thousands by filing datecall
PORTOLA PHARMACEUTICALS INC COM737010108Stock683,749$35,179,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM598,854$34,913,000thousands by filing date
ENDOLOGIX INC29266SAA4NOTE 2.250%12/140,941,000$34,602,000thousands by filing dateprincipal
XENOPORT INC98411C100COM6,287,374$34,518,000thousands by filing date
AMERISOURCEBERGEN COR000307108COMMON1,782,094$33,967,000thousands by filing date
INFINITY PHARMACEUTICALS INC45665G303COM4,305,288$33,797,000thousands by filing date
UNIVERSAL AMERN CORP NEW91338E101COM4,789,027$33,523,000thousands by filing date
WALGREENS BOOTS ALLIANCE INC931427108COM386,457$32,909,000thousands by filing date
EHEALTH INC28238P109COM3,264,588$32,581,000thousands by filing date
ENDOLOGIX INC29266SAB2NOTE 3.25011/030,000,000$32,548,000thousands by filing dateprincipal
HEALTHWAYS INC422245100COM2,465,042$31,725,000thousands by filing date
ACCURAY INC004397AB1CNV30,511,000$30,875,000thousands by filing dateprincipal
CHARLES RIV LABS INTL INC159864107COM377,188$30,322,000thousands by filing date
NIVALIS THERAPEUTICS INC65481J109COM3,732,412$28,889,000thousands by filing date
MCKESSON CORP COM58155Q103Stock144,646$28,529,000thousands by filing date
GENOMIC HEALTH, INC.37244C101COM809,432$28,492,000thousands by filing date
PACIRA BIOSCIENCES INC COM695127100Stock371,000$28,489,000thousands by filing date
FIVE PRIME THERAPEUTICS INC.33830X104Common Stock680,000$28,220,000thousands by filing date
KEMPHARM INC COM NEW488445107Stock1,420,497$28,211,000thousands by filing date
Sierra Oncology, Inc.74346L101common1,791,255$26,940,000thousands by filing date
RELYPSA INC759531106Common Stock900,281$25,514,000thousands by filing date
SPECTRANETICS CORP84760CAA5MTNF 2.625% 6/029,831,000$22,537,000thousands by filing dateprincipal
GW PHARMACEUTICALS PLC36197T103ADS310,122$21,535,000thousands by filing date
CYTOMX THERAPEUTICS INC23284F105COMMON STOCK946,022$19,743,000thousands by filing date
AERIE PHARMACEUTICALS INC00771V108COM807,875$19,672,000thousands by filing date
PROTEON THERAPEUTICS INC74371L109COM1,265,343$19,625,000thousands by filing date
RITEAID CORP767754104COM2,492,772$19,543,000thousands by filing date
REGENXBIO INC75901B107COM1,169,042$19,406,000thousands by filing date
XENCOR INC98401F105COMMON STOCK1,256,612$18,372,000thousands by filing date
PACIFIC BIOSCIENCES CALIF INC COM69404D108Stock1,388,000$18,224,000thousands by filing date
ACHILLION PHARMACEUTICALS IN00448Q201COM1,667,000$17,987,000thousands by filing date
STANDARD BIOTOOLS INC34385PAA6NOTE 2.750% 2/027,715,000$17,603,000thousands by filing dateprincipal
AXOGEN INC05463X106COM3,381,439$16,907,000thousands by filing date
DBV TECHNOLOGIES S A23306J101ADR461,869$16,770,000thousands by filing date
AKARI THERAPEUTICS PLC00972G108ADR1,150,700$16,685,000thousands by filing date
CENTENE CORP DEL COM15135B101Stock244,000$16,058,000thousands by filing date
MACROGENICS INC556099109COM517,920$16,040,000thousands by filing date
CARDIOVASCULAR SYSTEMS INC141619106COMMON STOCK1,035,000$15,649,000thousands by filing date
ENDOCHOICE HLDGS INC COM29272U103COM1,823,309$15,225,000thousands by filing date
ALIMERA SCIENCES INC016259103COM5,878,015$14,225,000thousands by filing date
IMPRIVATA INC45323J103Cmn1,206,418$13,633,000thousands by filing date
ALLSCRIPTS HEALTHCARE SOLUTN01988PAD0NOTE 1.250% 7/012,400,000$13,412,000thousands by filing dateprincipal
NANOSTRING TECHNOLOGIES INC63009R109COM880,622$12,954,000thousands by filing date
LAKEFRONT BIOTHERAPEUTICS NV36315X101SPON ADR183,000$11,507,000thousands by filing date
ACCELERON PHARMA INC00434H108COM213,491$10,410,000thousands by filing date
TRUPANION INC898202106COM1,062,214$10,367,000thousands by filing date
TONIX PHARMACEUTICALS HOLDING890260201COM NEW1,315,551$10,090,000thousands by filing date
INVUITY INC46187J205COM NEW1,078,218$9,510,000thousands by filing date
ESSA PHARMA INC29668H104COM1,859,282$8,499,000thousands by filing date
HEARTWARE INTL INC422368100COM159,961$8,062,000thousands by filing date
FOAMIX PHARMACEUTICALS LTDM46135105SHS948,934$7,696,000thousands by filing date
RIGEL PHARMACEUTICALS INC766559603COMMON STOCK2,397,855$7,266,000thousands by filing date
LOXO ONCOLOGY INC548862101COM251,000$7,141,000thousands by filing date
Alcobra LtdM2239P109SHS1,069,914$6,719,000thousands by filing date
NEOS THERAPEUTICS INC64052L106COM458,332$6,563,000thousands by filing date
VERSARTIS INC92529L102COM490,503$6,077,000thousands by filing date
OXFORD IMMUNOTEC GLOBAL PLCG6855A103ORD SHS519,670$5,976,000thousands by filing date
PSIVIDA CORP74440J101COM1,222,110$5,891,000thousands by filing date
CAS MED SYS INC124769209COM3,200,000$5,664,000thousands by filing date
MYOKARDIA INC62857M105COM375,000$5,498,000thousands by filing date
ZAFGEN INC98885E103COM843,665$5,307,000thousands by filing date
EGALET CORP28226B104COM477,123$5,258,000thousands by filing date
JAZZ INVESTMENTS I LTD472145AB7NOTE 1.875% 8/15,000,000$5,223,000thousands by filing dateprincipal
VOYAGER THERAPEUTICS INC92915B106COMMON STOCK235,294$5,153,000thousands by filing date
CATABASIS PHARMACEUTICALS IN14875P107COM643,580$5,104,000thousands by filing date
ANTARES PHARMA INC036642106COM3,983,440$4,820,000thousands by filing date
ALDEYRA THERAPEUTICS INC01438T106COM690,538$4,682,000thousands by filing date
TRACON PHARMACEUTICALS INC89237H100COM485,000$4,481,000thousands by filing date
GENOCEA BIOSCIENCES INC372427104COM837,257$4,412,000thousands by filing date
STEADYMED LTDM84920103SHS1,346,744$4,390,000thousands by filing date
SCYNEXIS INC COM NEW811292101Common Stock696,281$4,324,000thousands by filing date
Alliqua BioMedical Inc019621200COM NEW1,880,134$4,023,000thousands by filing date
GENESIS HEALTHCARE CLASS A37185X106COMMON STOCK963,564$3,344,000thousands by filing date
IMMUNOMEDICS INC452907108COM1,073,640$3,296,000thousands by filing date
TRINITY BIOTECH PLC896438306SPON ADR NEW246,000$2,893,000thousands by filing date
VERACYTE INC COM92337F107Stock392,147$2,823,000thousands by filing date
CTI BIOPHARMA CORP COM NEW12648L106Stock2,236,832$2,751,000thousands by filing date
ACURA PHARMACEUTICALS INC COM00509L802COM1,025,641$2,564,000thousands by filing date
TRILLIUM THERAPEUTICS INC COM NEW89620X506Stock172,307$2,173,000thousands by filing date
CIDARA THERAPEUTICS INC COM NEW171757107Stock119,456$2,050,000thousands by filing date
Elevance Health, Inc.036752103COM14,649$2,043,000thousands by filing date
ALPHATEC HOLDINGS INC02081G102COM4,982,738$1,495,000thousands by filing date
CAREDX INC14167L103COM229,000$1,466,000thousands by filing date
BOVIE MEDICAL CORP10211F100COM688,229$1,445,000thousands by filing date
PALATIN TECHNOLOGIES INC696077403COM PAR $ .012,000,000$1,328,000thousands by filing date
STREAMLINE HEALTH SOLUTIONS86323X106COM662,971$935,000thousands by filing date
AMRN 3.5 1/32220480AB3Bond 30/360P2 U1,000,000$901,000thousands by filing dateprincipal
RENNOVA HEALTH INC COM759757107Stock559,431$755,000thousands by filing date
CENCORA INC COM03073E105Stock3,000$311,000thousands by filing date
POZEN INC73941U102COMMON STOCK44,583$305,000thousands by filing date
RENNOVA HEALTH INC759757115*W EXP 12/30/202645,161$285,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001140361-16-053179this filing2016-02-16acceptance time not in the bulk data set