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13F-HR filed by Sofinnova Investments, Inc.

Sofinnova Investments, Inc. filed this 13F-HR for the quarter ended 2021-12-31, filed 2022-02-14, with 70 holding rows worth $1,712,054,000.

Accession
0001104659-22-022072
Filed
2022-02-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2021

A holdings report, 72 entries on the cover page, a total value of $1,712,054,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $1,712,054,000 with VALUE read as thousands by filing date, 13F file number 028-18774. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
NATERA INC COM632307104Stock3,102,960$289,785,000thousands by filing date
KARUNA THERAPEUTICS INC48576A100COM1,953,077$255,853,000thousands by filing date
VERA THERAPEUTICS INC92337R101COMMON STOCK2,914,776$77,883,000thousands by filing date
ROCHE HLDG LTD SPONS ADR (ISIN #US7711951043 SEDOL #B014J8)771195104ADR1,369,011$70,764,000thousands by filing date
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR499,824$67,241,000thousands by filing date
SPY78462F103SHS100,000$47,496,000thousands by filing dateput
AEROVATE THERAPEUTICS INC008064107COM3,758,686$44,315,000thousands by filing date
AbbVie,Inc.00287Y109COM312,018$42,247,000thousands by filing date
INVESCO QQQ TR46090E103COM100,000$39,785,000thousands by filing dateput
Y-mAbs Therapeutics Inc984241109Common Stock2,194,278$35,569,000thousands by filing date
iShares Russell 2000 ETF464287655SHS150,000$33,368,000thousands by filing dateput
REGENXBIO INC75901B107COM1,008,081$32,964,000thousands by filing date
TRAVERE THERAPEUTICS INC89422G107COM1,040,858$32,308,000thousands by filing date
UNITED THERAPEUTICS CORP DEL COM91307C102Stock129,754$28,037,000thousands by filing date
HERON THERAPEUTICS INC427746102COM2,933,351$26,781,000thousands by filing date
CHEMOCENTRYX INC16383L106COM731,222$26,624,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM245,182$26,261,000thousands by filing date
ALIGN TECHNOLOGY INC COM016255101Stock38,159$25,077,000thousands by filing date
HORIZON THERAPEUTICS PLCG46188101SHS221,792$23,900,000thousands by filing date
GUARDANT HEALTH INC COM40131M109Stock232,563$23,261,000thousands by filing date
XENCOR INC98401F105COMMON STOCK537,030$21,546,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW464,366$21,166,000thousands by filing date
BIOCRYST PHARMACEUTICALS INC COM09058V103Stock1,510,473$20,920,000thousands by filing date
SYNDAX PHARMACEUTICALS INC87164F105COM951,226$20,822,000thousands by filing date
IRHYTHM HOLDINGS INC COM450056106Stock168,882$19,876,000thousands by filing date
DEXCOM INC COM252131107Stock32,404$17,399,000thousands by filing date
PROTAGONIST THERAPEUTICS74366E102COM482,257$16,493,000thousands by filing date
INHIBRX INC45720L107COM368,679$16,100,000thousands by filing date
NEXTCURE INC65343E108COM2,671,856$16,031,000thousands by filing date
GALERA THERAPEUTICS EQUICLASS EQUITY36338D108COMMON STOCK3,083,712$14,154,000thousands by filing date
INOZYME PHARMA INC45790W108COM2,028,308$13,833,000thousands by filing date
IMMATICS N.VN44445109SHS1,026,623$13,798,000thousands by filing date
BOLT BIOTHERAPEUTICS INC097702104COM2,754,437$13,497,000thousands by filing date
IVERIC BIO INC46583P102COM798,789$13,356,000thousands by filing date
NUCANA PLC67022C106ADR5,599,999$13,328,000thousands by filing date
JOUNCE THERAPEUTICS INC481116101COM1,582,777$13,216,000thousands by filing date
IMMUNOGEN INC45253H101COMMON STOCK1,749,882$12,984,000thousands by filing date
AKOUOS INC00973J101COM1,515,074$12,878,000thousands by filing date
INSMED INC COM PAR $.01457669307Stock441,773$12,034,000thousands by filing date
FULCRUM THERAPEUTICS INC359616109COMMON STOCK617,670$10,927,000thousands by filing date
SAREPTA THERAPEUTICS INC803607100COM120,732$10,872,000thousands by filing date
CELLDEX THERAPEUTICS INC NEW15117B202COM NEW271,533$10,492,000thousands by filing date
CHECKMATE PHARMACEUTICALS IN162818108COM3,606,707$10,351,000thousands by filing date
PROTAGONIST THERAPEUTICS74366E102COM300,600$10,281,000thousands by filing datecall
UNIQURE NVN90064101SHS495,025$10,267,000thousands by filing date
ObsEva SAH5861P103COM4,749,623$9,452,000thousands by filing date
VIR BIOTECHNOLOGY INC92764N102COM200,000$8,374,000thousands by filing dateput
BIOMARIN PHARMACEUTICAL INC09061G101COM87,322$7,715,000thousands by filing date
ZYMEWORKS INC98985W102COM392,712$6,437,000thousands by filing date
AGENUS INC00847G705COM NEW1,961,032$6,315,000thousands by filing date
Nucana PLCGB00BYWYVCOMMON SHARES2,400,000$5,712,000thousands by filing date
Inflarx NvN44821101COM1,161,736$5,530,000thousands by filing date
ADICET BIO INC007002108COM310,988$5,439,000thousands by filing date
PTC THERAPEUTICS INC69366J200COM132,448$5,275,000thousands by filing date
KURA ONCOLOGY INC COM50127T109Stock369,173$5,168,000thousands by filing date
SIERRA ONCOLOGY INC82640U404CMN212,281$4,615,000thousands by filing date
AXSOME THERAPEUTICS INC. COM05464T104Stock100,000$3,778,000thousands by filing dateput
NOVOCURE LTDG6674U108ORD SHS50,000$3,754,000thousands by filing datecall
INTRA-CELLULAR THERAPIES INC46116X101COMMON STOCK56,915$2,979,000thousands by filing date
KURA ONCOLOGY INC COM50127T109Stock175,000$2,450,000thousands by filing datecall
INTERCEPT PHARMACEUTICALS IN45845P108COM150,400$2,450,000thousands by filing datecall
CYTEIR THERAPEUTICS INC23284P103COMMON179,450$2,040,000thousands by filing date
MARINUS PHARMACEUTICALS INC56854Q200COM NEW171,338$2,035,000thousands by filing date
INKT603693102Stock345,499$1,541,000thousands by filing date
ALIGOS THERAPEUTICS INC COM NEW01626L105Stock127,791$1,517,000thousands by filing date
SYNLOGIC INC87166L100COM574,972$1,391,000thousands by filing date
PDS BIOTECHNOLOGY CORP70465T107COM142,635$1,155,000thousands by filing date
FUSION PHARMACEUTICALS INC36118A100COM78,066$326,000thousands by filing date
INSULET CORP COM45784P101Stock1,066$284,000thousands by filing date
EDWARDS LIFESCIENCES CORP COM28176E108Stock1,406$182,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001104659-22-022072this filing2022-02-14acceptance time not in the bulk data set