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13F-HR filed by Sofinnova Investments, Inc.

Sofinnova Investments, Inc. filed this 13F-HR for the quarter ended 2021-09-30, filed 2021-11-15, with 70 holding rows worth $1,688,544,000.

Accession
0001104659-21-138952
Filed
2021-11-15
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q3 2021

A holdings report, 70 entries on the cover page, a total value of $1,688,544,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $1,688,544,000 with VALUE read as thousands by filing date, 13F file number 028-18774. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
NATERA INC COM632307104Stock3,102,960$345,794,000thousands by filing date
KARUNA THERAPEUTICS INC48576A100COM1,953,077$238,920,000thousands by filing date
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR499,824$79,667,000thousands by filing date
AEROVATE THERAPEUTICS INC008064107COM3,758,686$78,857,000thousands by filing date
ASTRAZENECA PLC SPONSORED ADR046353108ADR1,128,272$67,764,000thousands by filing date
Y-mAbs Therapeutics Inc984241109Common Stock2,194,278$62,625,000thousands by filing date
VERA THERAPEUTICS INC92337R101COMMON STOCK2,914,776$50,571,000thousands by filing date
MERCK & CO INC58933Y905CALL600,000$45,066,000thousands by filing datecall
UNITED THERAPEUTICS CORP DEL COM91307C102Stock222,094$40,994,000thousands by filing date
BOLT BIOTHERAPEUTICS INC097702104COM2,754,437$34,844,000thousands by filing date
ALIGN TECHNOLOGY INC COM016255101Stock47,000$31,275,000thousands by filing date
AbbVie,Inc.00287Y109COM272,600$29,405,000thousands by filing date
GALERA THERAPEUTICS EQUICLASS EQUITY36338D108COMMON STOCK3,083,712$24,978,000thousands by filing date
HERON THERAPEUTICS INC427746102COM2,301,179$24,600,000thousands by filing date
BRISTOL-MYERS SQUIBB CO110122908CALL400,000$23,668,000thousands by filing datecall
INOZYME PHARMA INC45790W108COM2,028,308$23,508,000thousands by filing date
DEXCOM INC COM252131107Stock37,266$20,379,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM181,860$18,697,000thousands by filing date
REGENERON PHARMACEUTICALS75886F957COM30,000$18,155,000thousands by filing dateput
NEXTCURE INC65343E108COM2,671,856$18,008,000thousands by filing date
AKOUOS INC00973J101COM1,515,074$17,590,000thousands by filing date
UNITED THERAPEUTICS CORP DEL91307C952PUT94,500$17,443,000thousands by filing dateput
HORIZON THERAPEUTICS PLCG46188101SHS157,487$17,251,000thousands by filing date
REATA PHARMACEUTICALS INC75615P103CL A157,488$15,845,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW426,632$15,248,000thousands by filing date
ObsEva SAH5861P103COM4,749,623$14,771,000thousands by filing date
ZOETIS INC CL A98978V103Stock76,000$14,755,000thousands by filing date
INSMED INC COM PAR $.01457669307Stock535,120$14,737,000thousands by filing date
SAREPTA THERAPEUTICS INC803607100COM157,279$14,545,000thousands by filing date
NUCANA PLC67022C106ADR5,599,999$14,448,000thousands by filing date
CHECKMATE PHARMACEUTICALS IN162818108COM3,606,707$14,319,000thousands by filing date
KURA ONCOLOGY INC COM50127T109Stock755,121$14,143,000thousands by filing date
AGENUS INC00847G705COM NEW2,344,410$12,308,000thousands by filing date
ZYMEWORKS INC98985W102COM410,619$11,924,000thousands by filing date
TRAVERE THERAPEUTICS INC89422G107COM437,280$10,604,000thousands by filing date
EXELIXIS INC COM30161Q104Stock488,414$10,325,000thousands by filing date
MIRATI THERAPEUTICS INC60468T105COM56,900$10,066,000thousands by filing date
BIOGEN INC COM09062X103Stock33,220$9,401,000thousands by filing date
KADMON HLDGS INC48283N106COM1,046,312$9,113,000thousands by filing date
CHEMOCENTRYX INC16383L106COM517,708$8,853,000thousands by filing date
CHEMOCENTRYX INC16383L956PUT505,800$8,649,000thousands by filing dateput
PTC THERAPEUTICS INC69366J200COM230,019$8,559,000thousands by filing date
INTRA-CELLULAR THERAPIES INC46116X101COMMON STOCK227,419$8,478,000thousands by filing date
ALX ONCOLOGY HOLDINGS INC00166B105COMMON STOCK107,220$7,919,000thousands by filing date
SYNDAX PHARMACEUTICALS INC87164F105COM413,841$7,909,000thousands by filing date
CELLDEX THERAPEUTICS INC NEW15117B202COM NEW137,032$7,398,000thousands by filing date
ACCELERON PHARMA INC00434H108COM39,589$6,813,000thousands by filing date
IMMATICS N.VN44445109SHS478,216$6,217,000thousands by filing date
Nucana PLCGB00BYWYVCOMMON SHARES2,400,000$6,192,000thousands by filing date
CTI BIOPHARMA CORP12648L601COM2,074,714$6,120,000thousands by filing date
IVERIC BIO INC46583P102COM357,400$5,804,000thousands by filing date
AMARIN CORP PLC023111206SPONS ADR NEW1,069,968$5,457,000thousands by filing date
REGENXBIO INC75901B107COM127,593$5,349,000thousands by filing date
PROTAGONIST THERAPEUTICS INC74366E902COM300,000$5,316,000thousands by filing datecall
PROTAGONIST THERAPEUTICS74366E102COM297,709$5,275,000thousands by filing date
GUARDANT HEALTH INC COM40131M109Stock40,000$5,000,000thousands by filing date
JOUNCE THERAPEUTICS INC481116101COM637,347$4,735,000thousands by filing date
SIERRA ONCOLOGY INC82640U404CMN206,564$4,528,000thousands by filing date
CYTEIR THERAPEUTICS INC23284P103COMMON246,321$4,323,000thousands by filing date
IVERIC BIO INC46583P952COM255,300$4,146,000thousands by filing dateput
NOVOCURE LTDG6674U908ORD SHS30,000$3,485,000thousands by filing datecall
INTERCEPT PHARMACEUTICALS IN45845P908COM190,000$2,822,000thousands by filing datecall
UNIQURE NVN90064101SHS78,742$2,521,000thousands by filing date
PDS BIOTECHNOLOGY CORP70465T107COM142,635$2,125,000thousands by filing date
ALIGOS THERAPEUTICS INC COM NEW01626L105Stock124,342$1,929,000thousands by filing date
MARINUS PHARMACEUTICALS INC56854Q200COM NEW166,711$1,897,000thousands by filing date
SYNLOGIC INC87166L100COM574,972$1,754,000thousands by filing date
FULCRUM THERAPEUTICS INC359616109COMMON STOCK51,006$1,439,000thousands by filing date
FUSION PHARMACEUTICALS INC36118A100COM78,066$618,000thousands by filing date
INSULET CORP COM45784P101Stock1,066$303,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001104659-21-138952this filing2021-11-15acceptance time not in the bulk data set