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13F-HR filed by Sofinnova Investments, Inc.

Sofinnova Investments, Inc. filed this 13F-HR for the quarter ended 2021-03-31, filed 2021-05-14, with 64 holding rows worth $1,663,412,000.

Accession
0001104659-21-066745
Filed
2021-05-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q1 2021

A holdings report, 64 entries on the cover page, a total value of $1,663,412,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $1,663,412,000 with VALUE read as thousands by filing date, 13F file number 028-18774. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
NATERA INC COM632307104Stock3,100,560$314,831,000thousands by filing date
KARUNA THERAPEUTICS INC48576A100COM1,952,441$234,742,000thousands by filing date
BOLT BIOTHERAPEUTICS INC097702104COM2,754,437$90,649,000thousands by filing date
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR521,923$67,265,000thousands by filing date
Y-mAbs Therapeutics Inc984241109Common Stock2,194,278$66,355,000thousands by filing date
ASTRAZENECA PLC SPONSORED ADR046353108ADR1,035,732$51,497,000thousands by filing date
SELECT SECTOR SPDR TR81369Y959PUT400,000$46,696,000thousands by filing dateput
CHECKMATE PHARMACEUTICALS IN162818108COM3,606,707$43,785,000thousands by filing date
JAZZ PHARMACEUTICALS PLC SHS USDG50871105Stock255,928$42,067,000thousands by filing date
INOZYME PHARMA INC45790W108COM2,028,308$40,160,000thousands by filing date
UNITED THERAPEUTICS CORP DEL COM91307C102Stock215,054$35,972,000thousands by filing date
Eli Lilly and Company532457108COM180,501$33,721,000thousands by filing date
NUCANA PLC67022C106ADR5,599,999$27,944,000thousands by filing date
MERUS N VN5749R100COM1,311,039$27,388,000thousands by filing date
GALERA THERAPEUTICS EQUICLASS EQUITY36338D108COMMON STOCK3,083,712$27,198,000thousands by filing date
NEXTCURE INC65343E108COM2,671,856$26,745,000thousands by filing date
ALIGN TECHNOLOGY INC COM016255101Stock45,500$24,640,000thousands by filing date
ACCELERON PHARMA INC00434H108COM178,538$24,212,000thousands by filing date
REATA PHARMACEUTICALS INC75615P103CL A238,520$23,780,000thousands by filing date
MIRATI THERAPEUTICS INC60468T105COM138,030$23,645,000thousands by filing date
INTRA-CELLULAR THERAPIES INC46116X101COMMON STOCK655,001$22,224,000thousands by filing date
PTC THERAPEUTICS INC69366J200COM466,840$22,105,000thousands by filing date
INSMED INC COM PAR $.01457669307Stock618,950$21,081,000thousands by filing date
AKOUOS INC00973J101COM1,515,074$21,014,000thousands by filing date
GILEAD SCIENCES INC375558903COM300,000$19,389,000thousands by filing datecall
EXELIXIS INC COM30161Q104Stock839,181$18,957,000thousands by filing date
PROTAGONIST THERAPEUTICS74366E102COM654,900$16,962,000thousands by filing date
ObsEva SAH5861P103COM4,749,623$15,436,000thousands by filing date
UNIQURE NVN90064101SHS427,122$14,390,000thousands by filing date
REGENXBIO INC75901B107COM361,735$12,339,000thousands by filing date
HORIZON THERAPEUTICS PLCG46188101SHS133,997$12,333,000thousands by filing date
Nucana PLCGB00BYWYVCOMMON SHARES2,400,000$11,976,000thousands by filing date
Vertex Pharmaceuticals Incorporated92532F100COM45,700$9,820,000thousands by filing date
DEXCOM INC COM252131107Stock27,000$9,704,000thousands by filing date
Amgen Inc.031162100COM38,868$9,671,000thousands by filing date
AGENUS INC00847G705COM NEW3,478,201$9,461,000thousands by filing date
MIRUM PHARMACEUTICALS INC604749101COM476,401$9,442,000thousands by filing date
ATHIRA PHARMA INC04746L104COM509,168$9,369,000thousands by filing date
CHEMOCENTRYX INC16383L106COM179,999$9,223,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW389,720$9,065,000thousands by filing date
CHEMOCENTRYX INC16383L956PUT150,000$7,686,000thousands by filing dateput
TCR2 THERAPEUTICS INC87808K106COM336,682$7,434,000thousands by filing date
AMARIN CORP PLC023111206SPONS ADR NEW1,170,584$7,269,000thousands by filing date
SYNDAX PHARMACEUTICALS INC87164F105COM298,644$6,678,000thousands by filing date
COHERUS ONCOLOGY INC19249H103COM434,555$6,349,000thousands by filing date
ARENA PHARMACEUTICALS INC040047607COM NEW91,448$6,346,000thousands by filing date
MARINUS PHARMACEUTICALS INC56854Q200COM NEW370,351$5,733,000thousands by filing date
JOUNCE THERAPEUTICS INC481116101COM511,822$5,256,000thousands by filing date
INSULET CORP COM45784P101Stock17,500$4,566,000thousands by filing date
FATE THERAPEUTICS INC31189P102COM54,795$4,518,000thousands by filing date
REPLIMUNE GROUP INC76029N106COMMON STOCK142,209$4,339,000thousands by filing date
IMMATICS N.VN44445109SHS385,099$4,317,000thousands by filing date
ALIGOS THERAPEUTICS INC COM NEW01626L105Stock185,532$4,219,000thousands by filing date
APTOSE BIOSCIENCES INC COM03835T200Stock696,928$4,164,000thousands by filing date
HERON THERAPEUTICS INC427746902COM250,000$4,053,000thousands by filing datecall
BIOCRYST PHARMACEUTICALS INC COM09058V103Stock378,774$3,852,000thousands by filing date
SAVARA INC805111101COM1,737,450$3,614,000thousands by filing date
PUMA BIOTECHNOLOGY INC74587V107COMMON STOCK344,917$3,353,000thousands by filing date
OTONOMY INC68906L105COM1,251,256$3,191,000thousands by filing date
KURA ONCOLOGY INC COM50127T109Stock83,164$2,351,000thousands by filing date
MACROGENICS INC556099109COM73,201$2,331,000thousands by filing date
SYNLOGIC INC87166L100COM574,972$2,058,000thousands by filing date
CALITHERA BIOSCIENCES INC COM NEW13089P101Stock757,533$1,833,000thousands by filing date
PDS BIOTECHNOLOGY CORP70465T107COM142,635$649,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001104659-21-066745this filing2021-05-14acceptance time not in the bulk data set