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13F-HR filed by DEERFIELD MANAGEMENT COMPANY, L.P.

DEERFIELD MANAGEMENT COMPANY, L.P. filed this 13F-HR for the quarter ended 2021-12-31, filed 2022-02-14, with 127 holding rows worth $4,767,581,000.

Accession
0000950159-22-000077
Filed
2022-02-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2021

A holdings report, 127 entries on the cover page, a total value of $4,767,581,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $4,767,581,000 with VALUE read as thousands by filing date, 13F file number 028-05366. The quarter's positions are built on this report. The resolved quarter.

Other managers

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
NUVALENT INC COM670703107Stock19,341,024$368,253,000thousands by filing date
VIATRIS INC COM92556V106Stock20,774,000$281,072,000thousands by filing date
ADAPTHEALTH CORP00653Q102COMMON STOCK10,225,445$250,114,000thousands by filing date
GLAUKOS CORP377322AB8BOND204,700,000$242,436,000thousands by filing dateprincipal
INVITAE CORP46185LAB9NOTE 2.000% 9/0163,385,000$153,337,000thousands by filing dateprincipal
AERIE PHARMACEUTICALS INC00771VAB4NOTE 1.500%10/0157,390,000$130,154,000thousands by filing dateprincipal
CAREMAX INC14171W103COM16,778,750$128,861,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM1,377,945$117,360,000thousands by filing date
ENVISTA HOLDINGS CORPORATION29415FAB0BOND52,500,000$116,547,000thousands by filing dateprincipal
NATERA INC632307AB0BOND45,000,000$115,754,000thousands by filing dateprincipal
SINGULAR GENOMICS SYSTEMS IN82933R100COM9,112,019$105,335,000thousands by filing date
NUVASIVE INC670704AL9BOND96,966,000$96,617,000thousands by filing dateprincipal
PACIRA BIOSCIENCES INC695127AF7NOTE 0.750% 8/081,600,000$90,486,000thousands by filing dateprincipal
CENTENE CORP DEL COM15135B101Stock1,003,800$82,713,000thousands by filing date
TABULA RASA HEALTHCARE INC873379AA9NOTE97,816,000$80,473,000thousands by filing dateprincipal
IVERIC BIO INC46583P102COM4,761,138$79,606,000thousands by filing date
ORGANOGENESIS HOLDINGS INC68621F102COMMON STOCK8,456,876$78,142,000thousands by filing date
INSULET CORP45784PAK7NOTE 0.375% 9/057,581,000$76,356,000thousands by filing dateprincipal
PULMONX CORP745848101COM2,366,867$75,905,000thousands by filing date
NUVASIVE INC670704AJ4NOTE 0.375% 3/177,859,000$74,729,000thousands by filing dateprincipal
NEVRO CORP64157FAC7NOTE 2.750% 4/061,000,000$68,194,000thousands by filing dateprincipal
SILK ROAD MEDICAL INC82710M100COMMON STOCK1,517,181$64,647,000thousands by filing date
LARIMAR THERAPEUTICS INC517125100COM5,830,249$62,908,000thousands by filing date
SEMA4 HOLDINGS CORP81663L101COM13,966,824$62,292,000thousands by filing date
EDGEWISE THERAPEUTICS INC28036F105COM3,933,137$60,098,000thousands by filing date
BRIDGEBIO PHARMA INC10806XAB8NOTE 2.500% 3/180,000,000$58,890,000thousands by filing dateprincipal
DECIPHERA PHARMACEUTICALS IN24344T101COM5,580,456$54,521,000thousands by filing date
INTERCEPT PHARMACEUTICALS IN45845PAA6NOTE 3.250% 7/057,791,000$54,417,000thousands by filing dateprincipal
APRIA INC03836A101COMMON STOCK1,655,795$53,979,000thousands by filing date
MIRUM PHARMACEUTICALS INC604749101COM3,282,912$52,362,000thousands by filing date
GLAUKOS CORP COM377322102Stock1,161,414$51,613,000thousands by filing date
INSMED INC457669AA7NOTE 1.750% 1/150,000,000$51,321,000thousands by filing dateprincipal
KURA ONCOLOGY INC COM50127T109Stock3,513,756$49,193,000thousands by filing date
APELLIS PHARMACEUTICALS INC03753UAB2NOTE 3.500% 9/128,825,000$43,542,000thousands by filing dateprincipal
MOLINA HEALTHCARE INC60855R100COM134,989$42,937,000thousands by filing date
ALPHATEC HLDGS INC02081G201COM NEW3,594,829$41,089,000thousands by filing date
PROTAGONIST THERAPEUTICS74366E102COM1,172,943$40,115,000thousands by filing date
Day One Biopharmaceuticals Inc23954D109Common Stock2,202,533$37,113,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW809,000$36,874,000thousands by filing date
PACIRA BIOSCIENCES INC COM695127100Stock596,338$35,882,000thousands by filing date
NOVAVAX INC670002AB0NOTE 3.750% 2/025,000,000$34,424,000thousands by filing dateprincipal
Xilio Therapeutics Inc.98422T100COM2,154,061$33,739,000thousands by filing date
AERIE PHARMACEUTICALS INC00771V108COM4,695,020$32,959,000thousands by filing date
STARLING ONCOLOGY INC68236X100COMMON STOCK3,296,107$32,137,000thousands by filing date
NUVATION BIO INC COM CL A67080N101Stock3,577,233$30,406,000thousands by filing date
SPRINGWORKS THERAPEUTICS INC85205L107COM452,000$28,015,000thousands by filing date
ESPERION THERAPEUTICS INC NEW COM29664W105Stock5,000,000$25,000,000thousands by filing date
BIOCRYST PHARMACEUTICALS INC COM09058V103Stock1,686,140$23,353,000thousands by filing date
MERIDIAN BIOSCIENCE INC589584101COMMON STOCK1,125,083$22,952,000thousands by filing date
FIGS INC CLASS A30260D103COMMON STOCK829,707$22,867,000thousands by filing date
PHARVARIS NVN69605108COMMON STOCK1,581,331$22,755,000thousands by filing date
REVOLUTION MEDICINES INC COM76155X100Stock891,587$22,441,000thousands by filing date
BROOKDALE SR LIVING INC112463104COM4,274,808$22,058,000thousands by filing date
ALECTOR INC014442107COMMON STOCK1,055,192$21,790,000thousands by filing date
HEALTH CATALYST INC42225TAB3BOND15,000,000$21,789,000thousands by filing dateprincipal
XERIS PHARMACEUTICALS INC98422LAA5NOTE 5.000% 7/118,000,000$21,577,000thousands by filing dateprincipal
BELLUS HEALTH INC NEW07987C204COM2,449,000$19,714,000thousands by filing date
PROFOUND MED CORP74319B502COM NEW1,713,797$19,246,000thousands by filing date
RHYTHM PHARMACEUTICALS INC76243J105COM1,867,467$18,637,000thousands by filing date
OUTSET MEDICAL INC690145107COM400,622$18,465,000thousands by filing date
NEVRO CORP64157F103COM216,000$17,511,000thousands by filing date
KINNATE BIOPHARMA INC49705R105COM985,568$17,464,000thousands by filing date
BRIDGEBIO PHARMA INC10806X102COM1,000,000$16,680,000thousands by filing datecall
ONCORUS INC68236R103COM3,148,977$16,595,000thousands by filing date
TERNS PHARMACEUTICALS INC COM880881107Stock2,345,959$16,586,000thousands by filing date
APELLIS PHARMACEUTICALS INC03753U106COM343,213$16,227,000thousands by filing date
INOZYME PHARMA INC45790W108COM2,344,786$15,991,000thousands by filing date
DA32 LIFE SCNCE TEC ACQSTN C23312M106CLASS A COM1,600,000$15,696,000thousands by filing date
KALVISTA PHARMACEUTICALS INC483497103COM1,175,131$15,547,000thousands by filing date
PTC THERAPEUTICS INC69366JAB7NOTE14,527,000$15,326,000thousands by filing dateprincipal
APOLLO ENDOSURGERY INC03767D108COM1,750,000$14,753,000thousands by filing date
VINCERX PHARMA INC92731L106COM NEW1,379,310$14,055,000thousands by filing date
MERUS N VN5749R100COM437,000$13,897,000thousands by filing date
COGENT BIOSCIENCES INC19240Q201COM1,601,000$13,737,000thousands by filing date
MIRATI THERAPEUTICS INC60468T105COM88,000$12,909,000thousands by filing date
SAREPTA THERAPEUTICS INC803607100COM141,000$12,697,000thousands by filing date
PMV PHARMACEUTICALS INC69353Y103COM522,000$12,058,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM110,000$11,782,000thousands by filing date
WEREWOLF THERAPEUTICS INC95075A107CMN958,125$11,411,000thousands by filing date
QUANTUM SI INC74765K105COM CL A1,400,000$11,018,000thousands by filing date
LIANBIO ADR53000N108COM1,782,747$10,982,000thousands by filing date
NYXOAH S AB6S7WD106SHS455,262$10,471,000thousands by filing date
CULLINAN THERAPEUTICS INC230031106COM671,690$10,364,000thousands by filing date
TRISALUS LIFE SCIENCES INC COM58507N105Stock999,999$9,880,000thousands by filing date
SARISSA CAPITAL ACQUISITN COG7823W102CMN999,999$9,790,000thousands by filing date
EUCRATES BIOMEDICAL ACQU CORG3141W106CMN999,999$9,760,000thousands by filing date
SENIOR CONNECT ACQUISITN COR81723H108COM CL A1,000,000$9,740,000thousands by filing date
REVOLUTION HEALTHCAR AQ CORP76155Y108CMN1,000,000$9,740,000thousands by filing date
GRAYBUG VISION INC COM38942Q103SHS5,281,713$9,666,000thousands by filing date
ORCHARD THERAPEUTICS PLC68570P101ADR6,949,416$9,173,000thousands by filing date
ACUTUS MED INC005111109COM2,648,386$9,031,000thousands by filing date
WEAVE COMMUNICATIONS INC94724R108COM554,519$8,418,000thousands by filing date
GUARDANT HEALTH INC40131MAB5NOTE 11/18,000,000$8,053,000thousands by filing dateprincipal
PRIVIA HEALTH GROUP INC74276R102COM300,000$7,761,000thousands by filing date
TURMERIC ACQUISITION CORPG9127T108CMN750,000$7,365,000thousands by filing date
HYPERFINE INC44916K106Common Stock1,000,000$7,250,000thousands by filing date
IGNYTE ACQUISITION CORP45175H106CMN725,000$7,062,000thousands by filing date
DEFINITIVE HEALTHCARE CORP24477E103CLASS A COM250,000$6,833,000thousands by filing date
ANNEXON INC03589W102COM583,913$6,709,000thousands by filing date
BENEFITFOCUS INC08180DAB2BOND6,500,000$6,229,000thousands by filing date
AMERICAN WELL CORP03044L105CL A991,115$5,986,000thousands by filing date
BIOATLA INC09077B104COM289,002$5,673,000thousands by filing date
ORION ACQUISITION CORP68626A108CMN500,000$4,890,000thousands by filing date
DELCATH SYSTEMS INC24661P807COMMON STOCK500,000$3,875,000thousands by filing date
PYXIS ONCOLOGY INC COMMON STOCK747324101Stock311,754$3,420,000thousands by filing date
NEOGENOMICS INC64049MAB6NOTE 0.250% 1/12,500,000$2,132,000thousands by filing dateprincipal
ROIVANT SCIENCES LTDG76279119*W EXP 09/30/2021,000,000$2,047,000thousands by filing date
GLAUKOS CORP COM377322102Stock45,200$2,009,000thousands by filing datecall
CABALETTA BIO INC12674W109COMMON STOCK464,252$1,760,000thousands by filing date
WAVE LIFE SCIENCES LTD SHSY95308105Stock552,690$1,735,000thousands by filing date
MEDAVAIL HOLDINGS INC58406B103COM1,142,552$1,600,000thousands by filing date
CAREMAX INC14171W111*W EXP 06/08/202672,000$941,000thousands by filing date
BUTTERFLY NETWORK INC124155110*W EXP 02/12/202733,333$931,000thousands by filing date
The Oncology Institute Inc W Exp 99/99/99968236X118SPAC Combination1,250,000$863,000thousands by filing date
QUANTUM SI INC74765K113*W EXP 06/10/202333,333$600,000thousands by filing date
SOMALOGIC INC83444k113WT120,000$401,000thousands by filing date
NUVATION BIO INC67080N119WARR166,666$315,000thousands by filing date
IGNYTE ACQUISITION CORP45175H114*W EXP 01/05/202362,500$279,000thousands by filing date
SENIOR CONNECT ACQUISITN COR81723H116*W EXP 12/31/202500,000$263,000thousands by filing date
EUCRATES BIOMEDICAL ACQU CORG3141W122*W EXP 10/23/202333,333$193,000thousands by filing date
SURROZEN INC86889P117*W EXP 08/01/203166,666$192,000thousands by filing date
MEDTECH ACQUISITION CORP58507N113*W EXP 12/22/202333,333$174,000thousands by filing date
TURMERIC ACQUISITION CORPG9127T124WTS250,000$170,000thousands by filing date
REVOLUTION HEALTHCAR AQ CORP76155Y116*W EXP 12/31/202200,000$150,000thousands by filing date
BIODELIVERY SCIENCES INTL IN09060J106COM29,204$91,000thousands by filing date
ORION ACQUISITION CORP68626A116WTS125,000$81,000thousands by filing date
WINDTREE THERAPEUTICS INC97382D303COM20,148$32,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0000950159-22-000077this filing2022-02-14acceptance time not in the bulk data set