13F-HR filed by Avidity Partners Management LP
Avidity Partners Management LP filed this 13F-HR for the quarter ended 2022-12-31, filed 2023-02-14, with 85 holding rows worth $4,615,991,045.
- Accession
- 0001791827-23-000002
- Filer
- CIK 1791827
- Filed
- 2023-02-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2022
A holdings report, 85 entries on the cover page, a total value of $4,615,991,045 stated on the cover page (in dollars after the unit check, H1), rows summing to $4,615,991,045 with VALUE read as dollars as filed, 13F file number 028-20028. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| SPDR SER TR | 78464A870 | S&P BIOTECH | 4,062,000 | $337,146,000 | dollars as filed | call |
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 625,000 | $236,768,750 | dollars as filed | |
| UNITED THERAPEUTICS CORP DEL COM | 91307C102 | Stock | 785,500 | $218,439,695 | dollars as filed | |
| NEUROCRINE BIOSCIENCES INC | 64125C109 | COM | 1,780,000 | $212,603,200 | dollars as filed | |
| AKERO THERAPEUTICS INC | 00973Y108 | COM | 3,825,000 | $209,610,000 | dollars as filed | |
| PROTHENA CORP PLC SHS | G72800108 | Stock | 2,953,000 | $177,918,250 | dollars as filed | |
| ARVINAS INC | 04335A105 | COM | 4,950,000 | $169,339,500 | dollars as filed | |
| Boston Scientific Corporation | 101137107 | COM | 3,256,700 | $150,687,509 | dollars as filed | |
| SYNDAX PHARMACEUTICALS INC | 87164F105 | COM | 5,861,000 | $149,162,450 | dollars as filed | |
| ULTRAGENYX PHARMACEUTICAL IN | 90400D108 | COM | 2,990,000 | $138,526,700 | dollars as filed | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 1,055,000 | $136,706,900 | dollars as filed | |
| MADRIGAL PHARMACEUTICALS INC COM | 558868105 | Stock | 430,000 | $124,807,500 | dollars as filed | |
| UNIVERSAL HLTH SVCS INC CL B | 913903100 | Stock | 825,600 | $116,318,784 | dollars as filed | |
| JAZZ PHARMACEUTICALS PLC SHS USD | G50871105 | Stock | 727,541 | $115,904,557 | dollars as filed | |
| ZENTALIS PHARMACEUTICALS INC | 98943L107 | COMMON STOCK | 5,150,000 | $103,721,000 | dollars as filed | |
| ACADIA HEALTHCARE COMPANY INC COM | 00404A109 | Stock | 1,165,000 | $95,902,800 | dollars as filed | |
| SURGERY PARTNERS INC | 86881A100 | COM | 3,112,000 | $86,700,320 | dollars as filed | |
| DEXCOM INC COM | 252131107 | Stock | 756,800 | $85,700,032 | dollars as filed | |
| ASTRAZENECA PLC SPONSORED ADR | 046353108 | ADR | 1,200,000 | $81,360,000 | dollars as filed | |
| Eli Lilly and Company | 532457108 | COM | 217,000 | $79,387,280 | dollars as filed | |
| VAXCYTE INC COM | 92243G108 | Stock | 1,615,400 | $77,458,430 | dollars as filed | |
| AVIDITY BIOSCIENCES INC COM | 05370A108 | Stock | 3,275,000 | $72,672,250 | dollars as filed | |
| NATERA INC COM | 632307104 | Stock | 1,798,900 | $72,261,813 | dollars as filed | |
| IDEAYA BIOSCIENCES INC COM | 45166A102 | Stock | 3,824,800 | $69,496,616 | dollars as filed | |
| IMMUNOCORE HLDGS PLC ADS | 45258D105 | ADR | 1,154,000 | $65,858,780 | dollars as filed | |
| ALTIMMUNE INC | 02155H200 | COM NEW | 3,990,000 | $65,635,500 | dollars as filed | |
| REVOLUTION MEDICINES INC COM | 76155X100 | Stock | 2,475,000 | $58,954,500 | dollars as filed | |
| KARUNA THERAPEUTICS INC | 48576A100 | COM | 299,000 | $58,753,500 | dollars as filed | |
| ARROWHEAD PHARMACEUTICALS IN | 04280A100 | COM | 1,375,000 | $55,770,000 | dollars as filed | |
| AXSOME THERAPEUTICS INC. COM | 05464T104 | Stock | 670,000 | $51,677,100 | dollars as filed | |
| Vertex Pharmaceuticals Incorporated | 92532F100 | COM | 172,000 | $49,670,160 | dollars as filed | |
| LEGEND BIOTECH CORP | 52490G102 | SPONSORED ADS | 970,000 | $48,422,400 | dollars as filed | |
| KEZAR LIFE SCIENCES INC | 49372L100 | COM | 6,782,400 | $47,748,096 | dollars as filed | |
| PLIANT THERAPEUTICS INC | 729139105 | COM | 2,240,400 | $43,306,932 | dollars as filed | |
| Ventyx Biosciences Inc | 92332V107 | Common Stock | 1,285,000 | $42,135,150 | dollars as filed | |
| ICON PUB LTD CO SHS | G4705A100 | Stock | 215,000 | $41,763,750 | dollars as filed | |
| QUEST DIAGNOSTICS INC COM | 74834L100 | Stock | 258,000 | $40,361,520 | dollars as filed | |
| BIO RAD LABS INC | 090572207 | CL A | 92,200 | $38,769,178 | dollars as filed | |
| BELLUS HEALTH INC NEW | 07987C204 | COM | 4,599,998 | $37,811,984 | dollars as filed | |
| TENET HEALTHCARE CORP COM NEW | 88033G407 | Stock | 717,300 | $34,997,067 | dollars as filed | |
| KARYOPHARM THERAPEUTICS INC | 48576U106 | COM | 9,633,911 | $32,755,297 | dollars as filed | |
| BIONTECH SE SPONSORED ADS | 09075V102 | ADR | 215,400 | $32,357,388 | dollars as filed | |
| VERVE THERAPEUTICS INC | 92539P101 | COM | 1,565,000 | $30,282,750 | dollars as filed | |
| ROCKET PHARMACEUTICALS INC | 77313F106 | COM | 1,527,087 | $29,885,093 | dollars as filed | |
| INTRA-CELLULAR THERAPIES INC | 46116X101 | COMMON STOCK | 504,000 | $26,671,680 | dollars as filed | |
| ARCUTIS BIOTHERAPEUTICS INC | 03969K108 | COM | 1,755,000 | $25,974,000 | dollars as filed | |
| PROMETHEUS BIOSCIENCES INC | 74349U108 | COM | 204,000 | $22,440,000 | dollars as filed | |
| INTELLIA THERAPEUTICS INC | 45826J105 | COM | 638,200 | $22,266,798 | dollars as filed | |
| VIR BIOTECHNOLOGY INC | 92764N102 | COM | 850,000 | $21,513,500 | dollars as filed | |
| PHATHOM PHARMACEUTICALS INC | 71722W107 | COMMON STOCK | 1,900,000 | $21,318,000 | dollars as filed | |
| BIOHAVEN LTD | G1110E107 | COM | 1,492,000 | $20,708,960 | dollars as filed | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 420,700 | $19,276,474 | dollars as filed | |
| DECIPHERA PHARMACEUTICALS IN | 24344T101 | COM | 1,126,000 | $18,455,140 | dollars as filed | |
| CARIBOU BIOSCIENCES INC COM | 142038108 | Stock | 2,882,600 | $18,102,728 | dollars as filed | |
| IVERIC BIO INC | 46583P102 | COM | 838,407 | $17,950,294 | dollars as filed | |
| POINT BIOPHARMA GLOBAL INC | 730541109 | COM | 2,432,400 | $17,732,196 | dollars as filed | |
| NANOSTRING TECHNOLOGIES INC | 63009R109 | COM | 2,057,200 | $16,395,884 | dollars as filed | |
| TWIST BIOSCIENCE CORP | 90184D100 | COM | 611,000 | $14,547,910 | dollars as filed | |
| BIOATLA INC | 09077B104 | COM | 1,260,000 | $10,395,000 | dollars as filed | |
| COMPASS THERAPEUTICS INC | 20454B104 | COM | 2,000,000 | $10,060,000 | dollars as filed | |
| SANGAMO THERAPEUTICS INC | 800677106 | COM | 2,748,300 | $8,629,662 | dollars as filed | |
| ALPINE IMMUNE SCIENCES INC | 02083G100 | COM | 1,028,200 | $7,557,270 | dollars as filed | |
| KINNATE BIOPHARMA INC | 49705R105 | COM | 1,212,700 | $7,397,470 | dollars as filed | |
| AN2 THERAPEUTICS INC | 037326105 | COM | 743,600 | $7,086,508 | dollars as filed | |
| CENTURY THERAPEUTICS INC | 15673T100 | COM | 1,303,600 | $6,687,468 | dollars as filed | |
| MEDICUS SCIENCES ACQUISITION | G5960S108 | CL A SHS | 520,000 | $5,236,400 | dollars as filed | |
| GRAPHITE BIO INC | 38870X104 | COM | 1,575,000 | $5,229,000 | dollars as filed | |
| ARYA SCIENCES ACQU CORP IV | G31659108 | COM | 500,000 | $5,050,000 | dollars as filed | |
| PANACEA ACQUISITION CORP II | G6882C106 | COM | 500,000 | $5,025,000 | dollars as filed | |
| ESSA PHARMA INC | 29668H708 | COM NEW | 1,855,400 | $4,675,608 | dollars as filed | |
| HEALTH SCIENCES ACQ CORP 2 | G4411D109 | ORD SHS | 400,000 | $3,992,000 | dollars as filed | |
| SYROS PHARMACEUTICALS INC | 87184Q206 | COM NEW | 900,000 | $3,231,000 | dollars as filed | |
| CYTEIR THERAPEUTICS INC | 23284P103 | COMMON | 1,795,800 | $2,963,070 | dollars as filed | |
| CAREMAX INC | 14171W103 | COM | 755,329 | $2,756,951 | dollars as filed | |
| SOCIAL CAP SUVRETTA HLDS CRP | G8253U103 | CMN | 200,000 | $2,012,000 | dollars as filed | |
| SOCIAL CAP SUVRETTA HLDS CP | G8253Y105 | CLASS A ORD SHS | 200,000 | $2,010,000 | dollars as filed | |
| SCYNEXIS INC | 811292200 | COM NEW | 1,140,600 | $1,779,336 | dollars as filed | |
| HYPERFINE INC | 44916K106 | Common Stock | 1,503,754 | $1,263,153 | dollars as filed | |
| FATE THERAPEUTICS INC | 31189P102 | COM | 104,653 | $1,055,949 | dollars as filed | |
| ZAI LAB LTD ADR | 98887Q104 | ADR | 31,309 | $961,186 | dollars as filed | |
| COLLEGIUM PHARMACEUTICAL INC | 19459J104 | COM | 37,898 | $879,234 | dollars as filed | |
| AC IMMUNE SA | H00263105 | SHS | 325,400 | $663,816 | dollars as filed | |
| REUNION NEUROSCIENCE INC | 76134G103 | COM | 560,300 | $504,270 | dollars as filed | |
| NUVATION BIO INC | 67080N119 | WARR | 99,999 | $14,450 | dollars as filed | |
| MEDICUS SCIENCES ACQUISITION | G5960S124 | *W EXP 02/12/202 | 57,770 | $5,199 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001791827-23-000002 | this filing | 2023-02-14 | acceptance time not in the bulk data set |