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13F-HR filed by Avidity Partners Management LP

Avidity Partners Management LP filed this 13F-HR for the quarter ended 2022-09-30, filed 2022-11-14, with 97 holding rows worth $4,918,761,000.

Accession
0001791827-22-000008
Filed
2022-11-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q3 2022

A holdings report, 98 entries on the cover page, a total value of $4,918,761,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $4,918,761,000 with VALUE read as thousands by filing date, 13F file number 028-20028. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
Eli Lilly and Company532457108COM1,007,000$325,613,000thousands by filing date
SPDR SERIES TRUST78464A900ST STR SP BIOT4,052,000$321,404,000thousands by filing datecall
UNITED THERAPEUTICS CORP DEL COM91307C102Stock970,200$203,140,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM1,855,700$197,094,000thousands by filing date
ARVINAS INC04335A105COM4,343,500$193,242,000thousands by filing date
ARGENX SE SPONSORED ADR04016X101ADR491,800$173,630,000thousands by filing date
BIOGEN INC COM09062X103Stock600,000$160,200,000thousands by filing date
Vertex Pharmaceuticals Incorporated92532F100COM512,800$148,476,000thousands by filing date
SYNDAX PHARMACEUTICALS INC87164F105COM5,586,900$134,253,000thousands by filing date
PROTHENA CORP PLC SHSG72800108Stock1,967,000$119,259,000thousands by filing date
SPDR SER TR78464A870S&P BIOTECH1,480,000$117,394,000thousands by filing date
ACADIA HEALTHCARE COMPANY INC COM00404A109Stock1,389,200$108,608,000thousands by filing date
AKERO THERAPEUTICS INC00973Y108COM3,122,000$106,304,000thousands by filing date
SAREPTA THERAPEUTICS INC803607100COM948,200$104,814,000thousands by filing date
HUMANA INC COM444859102Stock212,000$102,860,000thousands by filing date
Boston Scientific Corporation101137107COM2,538,600$98,320,000thousands by filing date
IMMUNOCORE HLDGS PLC ADS45258D105ADR2,079,100$97,593,000thousands by filing date
KARUNA THERAPEUTICS INC48576A100COM431,800$97,125,000thousands by filing date
Elevance Health, Inc.036752103COM207,600$94,300,000thousands by filing date
HORIZON THERAPEUTICS PLCG46188101SHS1,482,200$91,733,000thousands by filing date
ZENTALIS PHARMACEUTICALS INC98943L107COMMON STOCK4,223,100$91,472,000thousands by filing date
AVANTOR INC COM05352A100Stock4,522,600$88,643,000thousands by filing date
ULTRAGENYX PHARMACEUTICAL IN90400D108COM2,051,600$84,957,000thousands by filing date
NATERA INC COM632307104Stock1,735,000$76,028,000thousands by filing date
AXSOME THERAPEUTICS INC. COM05464T104Stock1,538,600$68,652,000thousands by filing date
CATALENT INC USD 0.01148806102COM940,000$68,018,000thousands by filing date
INTRA-CELLULAR THERAPIES INC46116X101COMMON STOCK1,402,500$65,258,000thousands by filing date
SEAGEN INC81181C104COM445,500$60,958,000thousands by filing date
BIO RAD LABS INC090572207CL A144,800$60,402,000thousands by filing date
ALNYLAM PHARMACEUTICALS INC COM02043Q107Stock288,500$57,746,000thousands by filing date
APELLIS PHARMACEUTICALS INC03753U106COM844,000$57,645,000thousands by filing date
INTELLIA THERAPEUTICS INC45826J105COM999,100$55,910,000thousands by filing date
IDEAYA BIOSCIENCES INC COM45166A102Stock3,715,400$55,434,000thousands by filing date
KEZAR LIFE SCIENCES INC49372L100COM5,414,400$46,618,000thousands by filing date
BELLUS HEALTH INC NEW07987C204COM4,346,700$45,901,000thousands by filing date
REVOLUTION MEDICINES INC COM76155X100Stock2,321,200$45,774,000thousands by filing date
AVIDITY BIOSCIENCES INC COM05370A108Stock2,600,000$42,458,000thousands by filing date
JAZZ PHARMACEUTICALS PLC SHS USDG50871105Stock318,300$42,426,000thousands by filing date
ZAI LAB LTD ADR98887Q104ADR1,234,000$42,203,000thousands by filing date
ARROWHEAD PHARMACEUTICALS IN04280A100COM1,255,374$41,490,000thousands by filing date
PLIANT THERAPEUTICS INC729139105COM1,981,100$41,385,000thousands by filing date
DEXCOM INC COM252131107Stock467,600$37,661,000thousands by filing date
Stryker Corporation863667101COM184,700$37,409,000thousands by filing date
VERVE THERAPEUTICS INC92539P101COM1,042,706$35,817,000thousands by filing date
ALTIMMUNE INC02155H200COM NEW2,684,000$34,275,000thousands by filing date
CENTENE CORP DEL COM15135B101Stock432,400$33,645,000thousands by filing date
CARIBOU BIOSCIENCES INC COM142038108Stock3,172,600$33,471,000thousands by filing date
ASTRAZENECA PLC SPONSORED ADR046353108ADR563,200$30,886,000thousands by filing date
NGM BIOPHARMACEUTICALS INC62921N105COM1,798,100$23,519,000thousands by filing date
DECIPHERA PHARMACEUTICALS IN24344T101COM1,191,800$22,048,000thousands by filing date
POINT BIOPHARMA GLOBAL INC730541109COM2,820,000$21,799,000thousands by filing date
PHATHOM PHARMACEUTICALS INC71722W107COMMON STOCK1,906,800$21,127,000thousands by filing date
COGENT BIOSCIENCES INC19240Q201COM1,357,700$20,257,000thousands by filing date
NKARTA INC65487U108COMMON STOCK1,414,082$18,609,000thousands by filing date
BEONE MEDICINES LTD SPONSORED ADS07725L102ADR132,000$17,796,000thousands by filing date
SI BONE INC825704109COM996,700$17,402,000thousands by filing date
GOSSAMER BIO INC COM38341P102Stock1,450,000$17,371,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW335,000$16,231,000thousands by filing date
ARCUTIS BIOTHERAPEUTICS INC03969K108COM794,500$15,183,000thousands by filing date
VAXCYTE INC COM92243G108Stock628,700$15,089,000thousands by filing date
ALPHATEC HLDGS INC02081G201COM NEW1,715,000$14,989,000thousands by filing date
KINNATE BIOPHARMA INC49705R105COM1,212,611$14,491,000thousands by filing date
IOVANCE BIOTHERAPEUTICS INC462260100COM1,382,900$13,248,000thousands by filing date
AN2 THERAPEUTICS INC037326105COM742,630$12,907,000thousands by filing date
CENTURY THERAPEUTICS INC15673T100COM1,303,600$12,893,000thousands by filing date
TRANSMEDICS GROUP INC89377M109COM300,000$12,522,000thousands by filing date
SANGAMO THERAPEUTICS INC800677106COM2,360,800$11,568,000thousands by filing date
STOKE THERAPEUTICS INC86150R107COM891,100$11,442,000thousands by filing date
SEASPINE HLDGS CORP81255T108COM2,010,000$11,417,000thousands by filing date
NANOSTRING TECHNOLOGIES INC63009R109COM698,200$8,916,000thousands by filing date
ERASCA INC COM29479A108Stock982,500$7,664,000thousands by filing date
ALPINE IMMUNE SCIENCES INC02083G100COM998,600$7,190,000thousands by filing date
SURGERY PARTNERS INC86881A100COM267,600$6,262,000thousands by filing date
SYROS PHARMACEUTICALS INC87184Q206COM NEW900,000$5,796,000thousands by filing date
CAREMAX INC14171W103COM755,329$5,355,000thousands by filing date
MEDICUS SCIENCES ACQUISITIONG5960S108CL A SHS520,000$5,148,000thousands by filing date
BCLS ACQUISITION CORPG0904B105CMN500,000$5,010,000thousands by filing date
GRAPHITE BIO INC38870X104COM1,575,000$4,993,000thousands by filing date
ARYA SCIENCES ACQU CORP IVG31659108COM500,000$4,955,000thousands by filing date
PANACEA ACQUISITION CORP IIG6882C106COM500,000$4,900,000thousands by filing date
COMPASS THERAPEUTICS INC20454B104COM2,000,000$4,560,000thousands by filing date
ESSA PHARMA INC29668H708COM NEW2,460,000$4,477,000thousands by filing date
HEALTH SCIENCES ACQ CORP 2G4411D109ORD SHS400,000$3,960,000thousands by filing date
CYTEIR THERAPEUTICS INC23284P103COMMON1,806,200$3,468,000thousands by filing date
TANGO THERAPEUTICS INC87583X109COM813,700$2,946,000thousands by filing date
SCYNEXIS INC811292200COM NEW1,140,600$2,737,000thousands by filing date
SOCIAL CAP SUVRETTA HLDS CPG8253Y105CLASS A ORD SHS200,000$1,964,000thousands by filing date
SOCIAL CAP SUVRETTA HLDS CRPG8253U103CMN200,000$1,960,000thousands by filing date
ONCOSEC MED INC68234L306COM2,945,000$1,437,000thousands by filing date
HYPERFINE INC44916K106Common Stock1,503,754$1,218,000thousands by filing date
AC IMMUNE SAH00263105SHS274,876$869,000thousands by filing date
REUNION NEUROSCIENCE INC76134G103COM595,200$851,000thousands by filing date
SEMA4 HOLDINGS CORP81663L101COM950,000$834,000thousands by filing date
PHASEBIO PHARMACEUTICALS INC717224109COM4,361,365$768,000thousands by filing date
SCIENCE 37 HOLDINGS INC808644108COM430,000$692,000thousands by filing date
NUVATION BIO INC67080N119WARR99,999$18,000thousands by filing date
MEDICUS SCIENCES ACQUISITIONG5960S124*W EXP 02/12/20257,770$1,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001791827-22-000008this filing2022-11-14acceptance time not in the bulk data set