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13F-HR filed by Avidity Partners Management LP

Avidity Partners Management LP filed this 13F-HR for the quarter ended 2022-03-31, filed 2022-05-16, with 92 holding rows worth $4,802,645,000.

Accession
0001791827-22-000004
Filed
2022-05-16
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q1 2022

A holdings report, 92 entries on the cover page, a total value of $4,802,645,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $4,802,645,000 with VALUE read as thousands by filing date, 13F file number 028-20028. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
SPDR SERIES TRUST78464A900ST STR SP BIOT3,300,000$296,604,000thousands by filing datecall
ASTRAZENECA PLC SPONSORED ADR046353108ADR3,700,000$245,458,000thousands by filing date
AbbVie,Inc.00287Y109COM1,466,100$237,669,000thousands by filing date
ARVINAS INC04335A105COM2,915,300$196,200,000thousands by filing date
Elevance Health, Inc.036752103COM399,400$196,193,000thousands by filing date
Merck & Co.,Inc.58933Y105COM2,370,000$194,459,000thousands by filing date
AVANTOR INC COM05352A100Stock5,668,300$191,702,000thousands by filing date
BAXTER INTL INC071813109COM1,915,500$148,528,000thousands by filing date
ZENTALIS PHARMACEUTICALS INC98943L107COMMON STOCK3,176,999$146,587,000thousands by filing date
BIOHAVEN PHARMACEUTICAL HOLDING11196105COM1,231,000$145,960,000thousands by filing date
Vertex Pharmaceuticals Incorporated92532F100COM545,600$142,385,000thousands by filing date
UnitedHealth Group Inc91324P102COM259,600$132,388,000thousands by filing date
UNITED THERAPEUTICS CORP DEL COM91307C102Stock718,946$128,986,000thousands by filing date
HORIZON THERAPEUTICS PLCG46188101SHS1,131,400$119,035,000thousands by filing date
MIRATI THERAPEUTICS INC60468T105COM1,393,000$114,532,000thousands by filing date
IVERIC BIO INC46583P102COM6,475,400$108,981,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM1,160,000$108,750,000thousands by filing date
IOVANCE BIOTHERAPEUTICS INC462260100COM6,043,219$100,620,000thousands by filing date
Intuitive Surgical,Inc.46120E602COM325,000$98,046,000thousands by filing date
CATALENT INC USD 0.01148806102COM782,000$86,724,000thousands by filing date
HUMANA INC COM444859102Stock198,900$86,555,000thousands by filing date
SYNDAX PHARMACEUTICALS INC87164F105COM4,823,400$83,831,000thousands by filing date
BIOGEN INC COM09062X103Stock365,000$76,869,000thousands by filing date
ULTRAGENYX PHARMACEUTICAL IN90400D108COM869,000$63,107,000thousands by filing date
Johnson & Johnson478160104COM354,000$62,739,000thousands by filing date
ADICET BIO INC007002108COM3,120,000$62,306,000thousands by filing date
KEZAR LIFE SCIENCES INC49372L100COM3,518,000$58,469,000thousands by filing date
MCKESSON CORP COM58155Q103Stock189,500$58,012,000thousands by filing date
ARGENX SE SPONSORED ADR04016X101ADR176,000$55,495,000thousands by filing date
Boston Scientific Corporation101137107COM1,196,100$52,975,000thousands by filing date
NATERA INC COM632307104Stock1,300,000$52,884,000thousands by filing date
EDWARDS LIFESCIENCES CORP COM28176E108Stock440,000$51,797,000thousands by filing date
ARROWHEAD PHARMACEUTICALS IN04280A100COM955,000$43,920,000thousands by filing date
IMMUNOCORE HLDGS PLC ADS45258D105ADR1,363,800$40,778,000thousands by filing date
LEGEND BIOTECH CORP52490G102SPONSORED ADS1,095,000$39,792,000thousands by filing date
SPDR SER TR78464A870S&P BIOTECH440,000$39,547,000thousands by filing date
BAUSCH HEALTH COS INC COM071734107Stock1,694,700$38,724,000thousands by filing date
AVIDITY BIOSCIENCES INC COM05370A108Stock2,045,000$37,771,000thousands by filing date
INSMED INC COM PAR $.01457669307Stock1,354,539$31,832,000thousands by filing date
ALPHATEC HLDGS INC02081G201COM NEW2,735,600$31,459,000thousands by filing date
IDEAYA BIOSCIENCES INC COM45166A102Stock2,690,000$30,101,000thousands by filing date
CHEMOCENTRYX INC16383L106COM1,175,000$29,457,000thousands by filing date
AXSOME THERAPEUTICS INC. COM05464T104Stock711,000$29,428,000thousands by filing date
ARCUS BIOSCIENCES INC03969F109COM912,000$28,783,000thousands by filing date
INTELLIA THERAPEUTICS INC45826J105COM390,075$28,347,000thousands by filing date
PHATHOM PHARMACEUTICALS INC71722W107COMMON STOCK1,946,000$26,485,000thousands by filing date
CARIBOU BIOSCIENCES INC COM142038108Stock2,819,067$25,879,000thousands by filing date
NUVATION BIO INC COM CL A67080N101Stock4,855,006$25,537,000thousands by filing date
BELLUS HEALTH INC NEW07987C204COM3,685,000$25,353,000thousands by filing date
SEASPINE HLDGS CORP81255T108COM2,010,000$24,442,000thousands by filing date
PENUMBRA INC COM70975L107Stock104,000$23,102,000thousands by filing date
SI BONE INC825704109COM1,000,000$22,600,000thousands by filing date
VIR BIOTECHNOLOGY INC92764N102COM780,000$20,062,000thousands by filing date
VIRIDIAN THERAPEUTICS INC92790C104COM1,040,000$19,230,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM291,184$18,601,000thousands by filing date
ALTIMMUNE INC02155H200COM NEW2,865,000$17,448,000thousands by filing date
ESSA PHARMA INC29668H708COM NEW2,460,000$15,203,000thousands by filing date
SEAGEN INC81181C104COM100,000$14,405,000thousands by filing date
LAKEFRONT BIOTHERAPEUTICS NV36315X101SPON ADR215,000$13,334,000thousands by filing date
CENTURY THERAPEUTICS INC15673T100COM865,000$10,890,000thousands by filing date
ALPINE IMMUNE SCIENCES INC02083G100COM1,207,000$10,827,000thousands by filing date
APELLIS PHARMACEUTICALS INC03753U106COM210,000$10,670,000thousands by filing date
AN2 THERAPEUTICS INC037326105COM688,330$10,373,000thousands by filing date
ERASCA INC COM29479A108Stock995,000$8,557,000thousands by filing date
SENTINELONE INC81730H109CL A204,500$7,922,000thousands by filing date
CYTEIR THERAPEUTICS INC23284P103COMMON1,850,000$6,975,000thousands by filing date
PHASEBIO PHARMACEUTICALS INC717224109COM4,405,000$5,815,000thousands by filing date
CAREMAX INC14171W103COM755,329$5,642,000thousands by filing date
TANGO THERAPEUTICS INC87583X109COM721,000$5,465,000thousands by filing date
HYPERFINE INC44916K106Common Stock1,503,754$5,323,000thousands by filing date
MEDICUS SCIENCES ACQUISITIONG5960S108CL A SHS520,000$5,086,000thousands by filing date
BCLS ACQUISITION CORPG0904B105CMN500,000$4,935,000thousands by filing date
DYNAMICS SPECIAL PURPOSE COR268010105CLASS A COM500,000$4,935,000thousands by filing date
ARYA SCIENCES ACQU CORP IVG31659108COM500,000$4,900,000thousands by filing date
PANACEA ACQUISITION CORP IIG6882C106COM500,000$4,875,000thousands by filing date
MOONLAKE IMMUNOTHERAPEUTICSG4444C102COM400,000$4,440,000thousands by filing date
FIELD TRIP HEALTH LTD31656R102COM2,976,000$3,988,000thousands by filing date
HEALTH SCIENCES ACQ CORP 2G4411D109ORD SHS400,000$3,964,000thousands by filing date
GRAPHITE BIO INC38870X104COM710,000$3,621,000thousands by filing date
ONCOSEC MED INC68234L306COM2,945,000$3,387,000thousands by filing date
OTONOMY INC68906L105COM1,349,905$3,240,000thousands by filing date
SEMA4 HOLDINGS CORP81663L101COM950,000$2,917,000thousands by filing date
COMPASS THERAPEUTICS INC20454B104COM2,000,000$2,740,000thousands by filing date
GRITSTONE BIO INC39868T105COM560,000$2,307,000thousands by filing date
SCIENCE 37 HOLDINGS INC808644108COM430,000$2,301,000thousands by filing date
SCYNEXIS INC811292200COM NEW544,043$2,127,000thousands by filing date
SOCIAL CAP SUVRETTA HLD CRPIG8253W109CMN200,000$1,980,000thousands by filing date
SOCIAL CAP SUVRETTA HLDS CRPG8253T106CLASS A ORD SHS200,000$1,978,000thousands by filing date
SOCIAL CAP SUVRETTA HLDS CRPG8253U103CMN200,000$1,950,000thousands by filing date
SOCIAL CAP SUVRETTA HLDS CPG8253Y105CLASS A ORD SHS200,000$1,948,000thousands by filing date
NUVATION BIO INC67080N119WARR99,999$76,000thousands by filing date
MEDICUS SCIENCES ACQUISITIONG5960S124*W EXP 02/12/20257,770$25,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001791827-22-000004this filing2022-05-16acceptance time not in the bulk data set