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13F-HR filed by Avidity Partners Management LP

Avidity Partners Management LP filed this 13F-HR for the quarter ended 2021-09-30, filed 2021-11-15, with 105 holding rows worth $4,513,577,000.

Accession
0001791827-21-000006
Filed
2021-11-15
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q3 2021

A holdings report, 105 entries on the cover page, a total value of $4,513,577,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $4,513,577,000 with VALUE read as thousands by filing date, 13F file number 028-20028. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
SPDR SER TR78464A870S&P BIOTECH3,021,000$379,770,000thousands by filing datecall
ACCELERON PHARMA INC00434H108COM1,228,100$211,356,000thousands by filing datecall
MIRATI THERAPEUTICS INC60468T105COM1,062,400$187,949,000thousands by filing date
ARVINAS INC04335A105COM2,234,700$183,648,000thousands by filing date
AbbVie,Inc.00287Y109COM1,613,200$174,016,000thousands by filing date
Vertex Pharmaceuticals Incorporated92532F100COM926,400$168,040,000thousands by filing date
ZENTALIS PHARMACEUTICALS INC98943L107COMMON STOCK2,493,800$166,187,000thousands by filing date
AVANTOR INC COM05352A100Stock3,247,700$132,831,000thousands by filing date
BIOHAVEN PHARMACEUTICAL HOLDING11196105COM934,200$129,770,000thousands by filing date
SYNDAX PHARMACEUTICALS INC87164F105COM4,823,400$92,175,000thousands by filing date
REGENERON PHARMACEUTICALS COM75886F107Stock152,300$92,169,000thousands by filing date
SEAGEN INC81181C104COM537,000$91,183,000thousands by filing date
HORIZON THERAPEUTICS PLCG46188101SHS826,000$90,480,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM832,000$85,538,000thousands by filing date
ASTRAZENECA PLC SPONSORED ADR046353108ADR1,412,000$84,805,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM848,900$81,418,000thousands by filing date
ALNYLAM PHARMACEUTICALS INC COM02043Q107Stock427,000$80,622,000thousands by filing date
Eli Lilly and Company532457108COM330,000$76,247,000thousands by filing date
NUVATION BIO INC COM CL A67080N101Stock7,263,488$72,199,000thousands by filing date
NATERA INC COM632307104Stock638,700$71,177,000thousands by filing date
HOLOGIC INC436440101COM945,400$69,780,000thousands by filing date
BAXTER INTL INC071813109COM862,000$69,331,000thousands by filing date
ARENA PHARMACEUTICALS INC040047607COM NEW1,139,000$67,827,000thousands by filing date
IVERIC BIO INC46583P102COM4,100,000$66,584,000thousands by filing date
UNITED THERAPEUTICS CORP DEL COM91307C102Stock351,000$64,788,000thousands by filing date
STEVANATO GROUP S P A ORD SHST9224W109Stock2,541,893$64,335,000thousands by filing date
SOTERA HEALTH CO83601L102COM2,378,000$62,185,000thousands by filing date
IDEAYA BIOSCIENCES INC COM45166A102Stock2,437,000$62,119,000thousands by filing date
CARIBOU BIOSCIENCES INC COM142038108Stock2,474,067$59,056,000thousands by filing date
CATALENT INC USD 0.01148806102COM398,000$52,962,000thousands by filing date
GRITSTONE BIO INC39868T105COM4,457,831$48,145,000thousands by filing date
LEGEND BIOTECH CORP52490G102SPONSORED ADS894,000$45,201,000thousands by filing date
ORTHO CLINICAL DIAGNOSTICS HG6829J107ORD SHS2,398,000$44,315,000thousands by filing date
Pfizer Inc.717081103COM1,026,800$44,163,000thousands by filing date
ARROWHEAD PHARMACEUTICALS IN04280A100COM673,700$42,059,000thousands by filing date
SHATTUCK LABS INC82024L103COMMON STOCK2,025,000$41,270,000thousands by filing date
ULTRAGENYX PHARMACEUTICAL IN90400D108COM455,000$41,036,000thousands by filing date
IMMUNOCORE HLDGS PLC ADS45258D105ADR1,095,600$40,614,000thousands by filing date
AVIDITY BIOSCIENCES INC COM05370A108Stock1,645,000$40,516,000thousands by filing date
IOVANCE BIOTHERAPEUTICS INC462260100COM1,462,200$36,058,000thousands by filing date
INSMED INC COM PAR $.01457669307Stock1,292,000$35,582,000thousands by filing date
EXACT SCIENCES CORP COM30063P105Stock369,000$35,221,000thousands by filing date
COMPASS PATHWAYS PLC20451W101SPONSORED ADS1,162,000$34,709,000thousands by filing date
ALPHATEC HLDGS INC02081G201COM NEW2,786,000$33,961,000thousands by filing date
INTELLIA THERAPEUTICS INC45826J105COM251,000$33,672,000thousands by filing date
NOVABRIDGE BIOSCIENCES44975P103CMN454,000$32,910,000thousands by filing date
SEASPINE HLDGS CORP81255T108COM1,943,000$30,563,000thousands by filing date
BELLUS HEALTH INC NEW07987C204COM4,942,000$30,344,000thousands by filing date
KYMERA THERAPEUTICS INC501575104COM514,500$30,222,000thousands by filing date
CYTEIR THERAPEUTICS INC23284P103COMMON1,683,441$29,544,000thousands by filing date
ALTIMMUNE INC02155H200COM NEW2,167,900$24,519,000thousands by filing date
VIR BIOTECHNOLOGY INC92764N102COM515,000$22,413,000thousands by filing date
ALPINE IMMUNE SCIENCES INC02083G100COM1,932,000$20,614,000thousands by filing date
ESSA PHARMA INC29668H708COM NEW2,450,000$19,600,000thousands by filing date
ADICET BIO INC007002108COM2,419,600$18,970,000thousands by filing date
CENTURY THERAPEUTICS INC15673T100COM739,269$18,600,000thousands by filing date
SI BONE INC825704109COM831,200$17,804,000thousands by filing date
SANA BIOTECHNOLOGY INC799566104COM774,644$17,445,000thousands by filing date
UIPATH INC90364P105CL A319,000$16,783,000thousands by filing date
FIELD TRIP HEALTH LTD31656R102COM3,581,000$16,437,000thousands by filing date
LIFESTANCE HEALTH GROUP INC53228F101COM1,000,000$14,500,000thousands by filing date
PHASEBIO PHARMACEUTICALS INC717224109COM4,405,000$13,700,000thousands by filing date
SEMA4 HOLDINGS CORP81663L101COM1,660,000$12,599,000thousands by filing date
GH RESEARCH PLC ORDINARY SHARESG3855L106Stock560,000$12,354,000thousands by filing date
GRAPHITE BIO INC38870X104COM748,995$12,276,000thousands by filing date
AC IMMUNE SAH00263105SHS1,739,600$11,673,000thousands by filing date
SCYNEXIS INC811292200COM NEW2,060,000$10,918,000thousands by filing date
WEREWOLF THERAPEUTICS INC95075A107CMN625,120$10,727,000thousands by filing date
SENTINELONE INC81730H109CL A200,000$10,714,000thousands by filing date
HARPOON THERAPEUTICS INC41358P106COM1,190,600$9,406,000thousands by filing date
ENGAGESMART INC29283F103COMMON STOCK275,000$9,367,000thousands by filing date
ACADIA PHARMACEUTICALS INC004225108COM550,000$9,136,000thousands by filing date
ORCHARD THERAPEUTICS PLC68570P101ADR3,836,798$8,825,000thousands by filing date
CAREMAX INC14171W103COM827,402$7,993,000thousands by filing date
ZETA GLOBAL HOLDINGS CORP CL A98956A105Stock1,300,000$7,618,000thousands by filing date
Instil Bio, Inc.45783C101Common Stock408,140$7,296,000thousands by filing date
MONTE ROSA THERAPEUTICS INC61225M102COM300,000$6,684,000thousands by filing date
ONCOSEC MED INC68234L306COM2,945,000$6,273,000thousands by filing date
TALARIS THERAPEUTICS INC87410C104COM455,000$6,170,000thousands by filing date
ACCELERON PHARMA INC00434H108COM35,000$6,024,000thousands by filing date
KEROS THERAPEUTICS INC COM492327101Stock145,100$5,740,000thousands by filing date
ZIOPHARM ONCOLOGY INC98973P101COM3,000,000$5,460,000thousands by filing date
MEDICUS SCIENCES ACQUISITIONG5960S108CL A SHS520,000$5,070,000thousands by filing date
ARYA SCIENCES ACQU CORP IVG31659108COM500,000$5,025,000thousands by filing date
BCLS ACQUISITION CORPG0904B105CMN500,000$4,980,000thousands by filing date
DYNAMICS SPECIAL PURPOSE COR268010105CLASS A COM500,000$4,970,000thousands by filing date
HEALTHCOR CATALIO ACQU CORPG44125105CL A SHS500,000$4,950,000thousands by filing date
PANACEA ACQUISITION CORP IIG6882C106COM500,000$4,885,000thousands by filing date
SOMALOGIC INC83444K105COM330,000$4,089,000thousands by filing date
HEALTH SCIENCES ACQ CORP 2G4411D109ORD SHS400,000$3,956,000thousands by filing date
MOONLAKE IMMUNOTHERAPEUTICSG4444C102COM400,000$3,940,000thousands by filing date
LIFESCI ACQUISITION II CORP53229E103COM400,000$3,920,000thousands by filing date
TANGO THERAPEUTICS INC87583X109COM300,000$3,879,000thousands by filing date
ZAI LAB LTD ADR98887Q104ADR35,600$3,752,000thousands by filing date
NAUTILUS BIOTECHNOLOGY INC63909J108COM600,000$3,684,000thousands by filing date
SIGHT SCIENCES INC82657M105COMMON STOCK145,189$3,296,000thousands by filing date
ATAIBECKLEY INCN0731H103Equity218,730$3,235,000thousands by filing date
KEZAR LIFE SCIENCES INC49372L100COM260,000$2,246,000thousands by filing date
SOCIAL CAP SUVRETTA HLDS CRPG8253T106CLASS A ORD SHS200,000$1,990,000thousands by filing date
SOCIAL CAP SUVRETTA HLDS CRPG8253U103CMN200,000$1,976,000thousands by filing date
SOCIAL CAP SUVRETTA HLDS CPG8253Y105CLASS A ORD SHS200,000$1,962,000thousands by filing date
SOCIAL CAP SUVRETTA HLD CRPIG8253W109CMN200,000$1,960,000thousands by filing date
NUVATION BIO INC67080N119WARR99,999$253,000thousands by filing date
SOMALOGIC INC83444k113WT65,999$228,000thousands by filing date
MEDICUS SCIENCES ACQUISITIONG5960S124*W EXP 02/12/20257,770$41,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001791827-21-000006this filing2021-11-15acceptance time not in the bulk data set