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13F-HR filed by Avidity Partners Management LP

Avidity Partners Management LP filed this 13F-HR for the quarter ended 2021-06-30, filed 2021-08-16, with 112 holding rows worth $3,699,847,000.

Accession
0001791827-21-000005
Filed
2021-08-16
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q2 2021

A holdings report, 112 entries on the cover page, a total value of $3,699,847,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $3,699,847,000 with VALUE read as thousands by filing date, 13F file number 028-20028. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
Vertex Pharmaceuticals Incorporated92532F100COM950,000$191,549,000thousands by filing date
AbbVie,Inc.00287Y109COM1,484,400$167,203,000thousands by filing date
ARVINAS INC04335A105COM1,854,000$142,758,000thousands by filing date
Eli Lilly and Company532457108COM565,500$129,794,000thousands by filing date
MARAVAI LIFESCIENCES HLDGS A56600D107COMMON STOCK2,963,545$123,669,000thousands by filing date
MIRATI THERAPEUTICS INC60468T105COM753,000$121,632,000thousands by filing date
ZENTALIS PHARMACEUTICALS INC98943L107COMMON STOCK2,160,000$114,912,000thousands by filing date
AVANTOR INC COM05352A100Stock3,180,000$112,922,000thousands by filing date
SEAGEN INC81181C104COM640,000$101,043,000thousands by filing date
BIOHAVEN PHARMACEUTICAL HOLDING11196105COM882,500$85,673,000thousands by filing date
HOLOGIC INC436440101COM1,208,800$80,651,000thousands by filing date
SYNDAX PHARMACEUTICALS INC87164F105COM4,615,000$79,240,000thousands by filing date
ESSA PHARMA INC29668H708COM NEW2,750,000$78,568,000thousands by filing date
EXACT SCIENCES CORP COM30063P105Stock590,000$73,343,000thousands by filing date
Medtronic PlcG5960L103COM535,000$66,410,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM681,000$66,275,000thousands by filing date
NUVATION BIO INC COM CL A67080N101Stock6,966,376$64,857,000thousands by filing date
ARENA PHARMACEUTICALS INC040047607COM NEW943,000$64,313,000thousands by filing date
BIOGEN INC COM09062X103Stock183,900$63,679,000thousands by filing date
NEOGENOMICS INC64049M209COM NEW1,367,000$61,747,000thousands by filing date
INTELLIA THERAPEUTICS INC45826J105COM380,000$61,526,000thousands by filing date
NOVABRIDGE BIOSCIENCES44975P103CMN729,000$61,200,000thousands by filing date
CATALENT INC USD 0.01148806102COM540,000$58,385,000thousands by filing date
SHATTUCK LABS INC82024L103COMMON STOCK1,940,200$56,246,000thousands by filing date
CENTENE CORP DEL COM15135B101Stock751,200$54,785,000thousands by filing date
HORIZON THERAPEUTICS PLCG46188101SHS568,000$53,188,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM563,200$49,539,000thousands by filing date
NATERA INC COM632307104Stock436,000$49,499,000thousands by filing date
SOTERA HEALTH CO83601L102COM1,910,000$46,279,000thousands by filing date
ACCELERON PHARMA INC00434H108COM358,500$44,988,000thousands by filing date
IDEAYA BIOSCIENCES INC COM45166A102Stock2,070,000$43,449,000thousands by filing date
UNITED THERAPEUTICS CORP DEL COM91307C102Stock236,400$42,413,000thousands by filing date
BRIDGEBIO PHARMA INC10806X102COM673,400$41,050,000thousands by filing date
ALPHATEC HLDGS INC02081G201COM NEW2,621,000$40,154,000thousands by filing date
TRILLIUM THERAPEUTICS INC COM NEW89620X506Stock4,105,000$39,819,000thousands by filing date
CYTEIR THERAPEUTICS INC23284P103COMMON1,808,394$38,700,000thousands by filing date
COMPASS PATHWAYS PLC20451W101SPONSORED ADS1,000,000$38,150,000thousands by filing date
CARDINAL HEALTH INC14149Y108COM654,200$37,348,000thousands by filing date
KADMON HLDGS INC48283N106COM9,294,600$35,970,000thousands by filing date
DYNAVAX TECHNOLOGIES CORP268158201COM NEW3,400,000$33,490,000thousands by filing date
ALNYLAM PHARMACEUTICALS INC COM02043Q107Stock195,000$33,056,000thousands by filing date
INSMED INC COM PAR $.01457669307Stock1,150,050$32,730,000thousands by filing date
SEASPINE HLDGS CORP81255T108COM1,524,998$31,278,000thousands by filing date
LIFESTANCE HEALTH GROUP INC53228F101COM1,100,000$30,646,000thousands by filing date
CENTURY THERAPEUTICS INC15673T100COM1,003,522$29,443,000thousands by filing date
LEGEND BIOTECH CORP52490G102SPONSORED ADS625,000$25,656,000thousands by filing date
IMMUNOCORE HLDGS PLC ADS45258D105ADR601,000$23,469,000thousands by filing date
ADICET BIO INC007002108COM2,250,500$23,158,000thousands by filing date
ACADIA PHARMACEUTICALS INC004225108COM940,000$22,927,000thousands by filing date
GRAPHITE BIO INC38870X104COM735,500$22,602,000thousands by filing date
HARPOON THERAPEUTICS INC41358P106COM1,500,000$20,805,000thousands by filing date
UIPATH INC90364P105CL A300,000$20,379,000thousands by filing date
GRITSTONE BIO INC39868T105COM2,122,064$19,374,000thousands by filing date
SI BONE INC825704109COM575,000$18,095,000thousands by filing date
ZAI LAB LTD ADR98887Q104ADR100,000$17,699,000thousands by filing date
ORCHARD THERAPEUTICS PLC68570P101ADR3,781,798$16,602,000thousands by filing date
ALDEYRA THERAPEUTICS INC01438T106COM1,450,000$16,429,000thousands by filing date
PHASEBIO PHARMACEUTICALS INC717224109COM4,315,000$16,052,000thousands by filing date
SYNEOS HEALTH INC87166B102CL A175,000$15,661,000thousands by filing date
SANA BIOTECHNOLOGY INC799566104COM778,597$15,307,000thousands by filing date
SCYNEXIS INC811292200COM NEW2,060,000$15,162,000thousands by filing date
ALPINE IMMUNE SCIENCES INC02083G100COM1,495,000$13,455,000thousands by filing date
BELLUS HEALTH INC NEW07987C204COM4,250,000$13,218,000thousands by filing date
AC IMMUNE SAH00263105SHS1,584,000$12,561,000thousands by filing date
GH RESEARCH PLC ORDINARY SHARESG3855L106Stock560,000$12,169,000thousands by filing date
NAUTILUS BIOTECHNOLOGY INC63909J108COM1,125,000$11,363,000thousands by filing date
WEREWOLF THERAPEUTICS INC95075A107CMN650,265$11,341,000thousands by filing date
ZETA GLOBAL HOLDINGS CORP CL A98956A105Stock1,300,000$10,920,000thousands by filing date
CAREMAX INC14171W103COM817,402$10,544,000thousands by filing date
PROTHENA CORP PLC SHSG72800108Stock182,000$9,357,000thousands by filing date
CARDIFF ONCOLOGY INC14147L108COM1,395,000$9,277,000thousands by filing date
MONDAY COM LTD SHSM7S64H106Stock40,000$8,944,000thousands by filing date
IVERIC BIO INC46583P102COM1,400,010$8,834,000thousands by filing date
DOXIMITY INC CL A26622P107Stock150,000$8,730,000thousands by filing date
ARROWHEAD PHARMACEUTICALS IN04280A100COM104,000$8,613,000thousands by filing date
SENTINELONE INC81730H109CL A200,000$8,500,000thousands by filing date
ESPERION THERAPEUTICS INC NEW COM29664W105Stock400,000$8,460,000thousands by filing date
ONCOSEC MED INC68234L306COM2,800,000$7,868,000thousands by filing date
Instil Bio, Inc.45783C101Common Stock400,000$7,728,000thousands by filing date
VIR BIOTECHNOLOGY INC92764N102COM162,000$7,659,000thousands by filing date
PHARVARIS NVN69605108COMMON STOCK400,000$7,452,000thousands by filing date
CM LIFE SCIENCES INC18978W109COM CL A525,000$7,355,000thousands by filing date
MONTE ROSA THERAPEUTICS INC61225M102COM300,000$6,810,000thousands by filing date
DENALI THERAPEUTICS INC COM24823R105Stock86,100$6,754,000thousands by filing date
ATAIBECKLEY INCN0731H103Equity350,987$6,493,000thousands by filing date
TALARIS THERAPEUTICS INC87410C104COM436,363$6,410,000thousands by filing date
ARYA SCIENCES ACQU CORP IVG31659108COM500,000$5,360,000thousands by filing date
BCLS ACQUISITION CORPG0904B105CMN500,000$5,265,000thousands by filing date
MEDICUS SCIENCES ACQUISITIONG5960S108CL A SHS520,000$5,018,000thousands by filing date
FIGS INC CLASS A30260D103COMMON STOCK100,000$5,010,000thousands by filing date
PANACEA ACQUISITION CORP IIG6882C106COM500,000$5,008,000thousands by filing date
DYNAMICS SPECIAL PURPOSE COR268010105CLASS A COM500,000$4,970,000thousands by filing date
HEALTHCOR CATALIO ACQU CORPG44125105CL A SHS500,000$4,925,000thousands by filing date
CELCUITY INC15102K100COM200,000$4,800,000thousands by filing date
CONFLUENT INC20717M103CLASS A COM100,000$4,750,000thousands by filing date
CM LIFE SCIENCES II INC125842203UNIT 02/25/2028330,000$4,439,000thousands by filing date
WALKME LTD ORD SHSM97628107Stock150,000$4,389,000thousands by filing date
MOONLAKE IMMUNOTHERAPEUTICSG4444C102COM400,000$4,140,000thousands by filing date
HEALTH SCIENCES ACQ CORP 2G4411D109ORD SHS400,000$4,080,000thousands by filing date
LIFESCI ACQUISITION II CORP53229E103COM400,000$4,000,000thousands by filing date
BCTG ACQUISITION CORP05492W103COM300,000$3,414,000thousands by filing date
ALPHA TEKNOVA INC02080L102COMMON STOCK100,000$2,373,000thousands by filing date
SOCIAL CAP SUVRETTA HLDS CRPG8253U103CMN200,000$2,024,000thousands by filing date
SOCIAL CAP SUVRETTA HLD CRPIG8253W109CMN200,000$2,022,000thousands by filing date
SOCIAL CAP SUVRETTA HLDS CRPG8253T106CLASS A ORD SHS200,000$2,022,000thousands by filing date
SOCIAL CAP SUVRETTA HLDS CPG8253Y105CLASS A ORD SHS200,000$2,020,000thousands by filing date
FLYWIRE CORPORATION302492103COM VTG50,000$1,837,000thousands by filing date
CLOVIS ONCOLOGY INC189464100COM271,726$1,576,000thousands by filing date
SINGULAR GENOMICS SYSTEMS IN82933R100COM50,000$1,374,000thousands by filing date
NEUROPACE INC641288105COMMON STOCK40,000$952,000thousands by filing date
NUVATION BIO INC67080N119WARR99,999$260,000thousands by filing date
MEDICUS SCIENCES ACQUISITIONG5960S124*W EXP 02/12/20257,770$58,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001791827-21-000005this filing2021-08-16acceptance time not in the bulk data set