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13F-HR filed by EcoR1 Capital, LLC

EcoR1 Capital, LLC filed this 13F-HR for the quarter ended 2022-03-31, filed 2022-05-16, with 87 holding rows worth $3,196,837,000.

Accession
0001567619-22-010677
Filed
2022-05-16
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q1 2022

A holdings report, 87 entries on the cover page, a total value of $3,196,837,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $3,196,837,000 with VALUE read as thousands by filing date, 13F file number 028-16764. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
PROTHENA CORP PLC SHSG72800108Stock11,584,280$423,637,000thousands by filing date
APELLIS PHARMACEUTICALS INC03753U106COM5,183,431$263,370,000thousands by filing date
LAKEFRONT BIOTHERAPEUTICS NV36315X101SPON ADR3,195,624$198,193,000thousands by filing date
ANAPTYSBIO INC032724106COM7,521,024$186,070,000thousands by filing date
SAREPTA THERAPEUTICS INC803607100COM2,069,634$161,680,000thousands by filing date
MORPHIC HLDG INC61775R105COM3,951,566$158,655,000thousands by filing date
ACADIA PHARMACEUTICALS INC004225108COM5,991,479$145,114,000thousands by filing date
XENCOR INC98401F105COMMON STOCK4,968,756$132,566,000thousands by filing date
KURA ONCOLOGY INC COM50127T109Stock6,638,371$106,745,000thousands by filing date
ARCUS BIOSCIENCES INC03969F109COM3,265,101$103,047,000thousands by filing date
ARVINAS INC04335A105COM1,503,929$101,214,000thousands by filing date
ZAI LAB LTD ADR98887Q104ADR2,223,212$97,777,000thousands by filing date
ALECTOR INC014442107COMMON STOCK5,738,448$81,773,000thousands by filing date
NUVATION BIO INC COM CL A67080N101Stock13,896,543$73,096,000thousands by filing date
RELAY THERAPEUTICS INC COM75943R102Stock2,291,441$68,583,000thousands by filing date
REATA PHARMACEUTICALS INC75615P103CL A1,975,611$64,721,000thousands by filing date
2SEVENTY BIO INC COMMON STOCK901384107Stock3,495,943$59,641,000thousands by filing date
CEREVEL THERAPEUTICS HLDNG I15678U128COM1,646,260$57,636,000thousands by filing date
AVIDITY BIOSCIENCES INC COM05370A108Stock2,759,505$50,968,000thousands by filing date
ATEA PHARMACEUTICALS INC04683R106COMMON STOCK6,340,639$45,779,000thousands by filing date
MIRATI THERAPEUTICS INC60468T105COM500,622$41,161,000thousands by filing date
ARGENX SE SPONSORED ADR04016X101ADR125,000$39,414,000thousands by filing date
DESIGN THERAPEUTICS INC25056L103COM2,371,445$38,299,000thousands by filing date
REVOLUTION MEDICINES INC COM76155X100Stock1,274,097$32,502,000thousands by filing date
VAXCYTE INC COM92243G108Stock1,304,741$31,509,000thousands by filing date
VOYAGER THERAPEUTICS INC92915B106COMMON STOCK3,557,507$27,108,000thousands by filing date
BICYCLE THERAPEUTICS PLC-ADR088786108SPONSORED ADS547,453$24,022,000thousands by filing date
EDGEWISE THERAPEUTICS INC28036F105COM2,359,808$22,890,000thousands by filing date
EXELIXIS INC COM30161Q104Stock951,333$21,567,000thousands by filing date
JANUX THERAPEUTICS INC47103J105COM1,421,319$20,382,000thousands by filing date
GERON CORP374163103COM14,285,714$19,429,000thousands by filing date
OVID THERAPEUTICS INC690469101COMMON STOCK6,117,400$19,209,000thousands by filing date
SPRINGWORKS THERAPEUTICS INC85205L107COM325,881$18,393,000thousands by filing date
ORIC PHARMACEUTICALS INC68622P109COM3,418,068$18,252,000thousands by filing date
Ventyx Biosciences Inc92332V107Common Stock1,300,000$17,641,000thousands by filing date
CRINETICS PHARMACEUTICALS INC COM22663K107Stock790,209$17,345,000thousands by filing date
ARCUTIS BIOTHERAPEUTICS INC03969K108COM895,503$17,247,000thousands by filing date
SURFACE ONCOLOGY INC86877M209COM4,653,000$13,680,000thousands by filing date
PMV PHARMACEUTICALS INC69353Y103COM649,786$13,529,000thousands by filing date
HOOKIPA PHARMA INC43906K100COM5,000,000$11,400,000thousands by filing date
CHINOOK THERAPEUTICS INC16961L106COM690,000$11,288,000thousands by filing date
AKOUOS INC00973J101COM1,975,984$9,386,000thousands by filing date
PROTAGONIST THERAPEUTICS74366E102COM381,711$9,039,000thousands by filing date
ALIGOS THERAPEUTICS INC COM NEW01626L105Stock3,948,360$8,489,000thousands by filing date
NGM BIOPHARMACEUTICALS INC62921N105COM541,108$8,252,000thousands by filing date
IGM BIOSCIENCES INC449585108COM298,597$7,981,000thousands by filing date
ERASCA INC COM29479A108Stock678,441$5,835,000thousands by filing date
TANGO THERAPEUTICS INC87583X109COM761,971$5,776,000thousands by filing date
FRAZIER LIFESCIENCES ACQU COG3710A105CMN587,615$5,776,000thousands by filing date
ZENTALIS PHARMACEUTICALS INC98943L107COMMON STOCK115,236$5,317,000thousands by filing date
GRAPHITE BIO INC38870X104COM1,024,279$5,224,000thousands by filing date
NUVATION BIO INC67080N119WARR963,333$5,067,000thousands by filing date
JIYA ACQUISITION CORP47760M102CMN500,000$4,915,000thousands by filing date
C4 THERAPEUTICS INC12529R107COM STK200,000$4,852,000thousands by filing date
CENTESSA PHARMACEUTICALS PLC152309100SPONSORED ADS454,545$4,077,000thousands by filing date
HEALTH SCIENCES ACQ CORP 2G4411D109ORD SHS400,000$3,964,000thousands by filing date
GRACELL BIOTECHNOLOGIES INC38406L103ADR1,559,710$3,634,000thousands by filing date
NURIX THERAPEUTICS INC67080M103COMMON STOCK254,473$3,565,000thousands by filing date
SOLID BIOSCIENCES INC COM NEW83422E105Stock2,565,102$3,078,000thousands by filing date
KRONOS BIO INC50107A104COM326,780$2,363,000thousands by filing date
ITEOS THERAPEUTICS INC46565G104COM72,821$2,343,000thousands by filing date
VERVE THERAPEUTICS INC92539P101COM98,593$2,250,000thousands by filing date
MOONLAKE IMMUNOTHERAPEUTICSG4444C102COM200,000$2,220,000thousands by filing date
DYNE THERAPEUTICS INC COM26818M108Stock215,000$2,073,000thousands by filing date
BCLS ACQUISITION CORPG0904B105CMN200,000$1,974,000thousands by filing date
KINNATE BIOPHARMA INC49705R105COM175,000$1,971,000thousands by filing date
5 01 ACQUISITION CORP33836P105CMN200,000$1,970,000thousands by filing date
EUCRATES BIOMEDICAL ACQU CORG3141W106CMN200,000$1,968,000thousands by filing date
AC IMMUNE SAH00263105SHS485,005$1,940,000thousands by filing date
ARYA SCIENCES ACQU CORP IVG31659108COM150,000$1,470,000thousands by filing date
PARDES BIOSCIENCES INC69945Q105COM200,000$1,394,000thousands by filing date
Adverum Biotechnologies, Inc.00773U108Common Stock1,046,700$1,371,000thousands by filing date
Mersana Therapeutics Inc59045L106Common Stock326,578$1,303,000thousands by filing date
ARS PHARMACEUTICALS INC82835W108COM329,537$1,157,000thousands by filing date
ATRECA INC04965G109COM358,780$1,137,000thousands by filing date
APPLIED MOLECULAR TRANS INC03824M109COM131,693$990,000thousands by filing date
TURMERIC ACQUISITION CORPG9127T108CMN100,000$985,000thousands by filing date
CAREMAX INC14171W111*W EXP 06/08/202100,000$747,000thousands by filing date
REPARE THERAPEUTICS INC760273102COM50,000$712,000thousands by filing date
CARIBOU BIOSCIENCES INC COM142038108Stock75,000$689,000thousands by filing date
EUCRATES BIOMEDICAL ACQU CORG3141W122*W EXP 10/23/20266,666$656,000thousands by filing datecall
FRAZIER LIFESCIENCES ACQU COG3710A113WTS66,665$655,000thousands by filing date
OMEGA ALPHA SPACG6749V107CL A50,000$491,000thousands by filing date
BOLT BIOTHERAPEUTICS INC097702104COM150,000$411,000thousands by filing date
TURMERIC ACQUISITION CORPG9127T124WTS33,333$328,000thousands by filing date
RADIUS HEALTH INC750469207COM NEW35,000$309,000thousands by filing date
SURROZEN INC86889P117*W EXP 08/01/20366,665$201,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001567619-22-010677this filing2022-05-16acceptance time not in the bulk data set