13F-HR filed by SPHERA FUNDS MANAGEMENT LTD.
SPHERA FUNDS MANAGEMENT LTD. filed this 13F-HR for the quarter ended 2022-09-30, filed 2022-11-14, with 74 holding rows worth $720,456,000.
- Accession
- 0001496201-22-000008
- Filer
- CIK 1496201
- Filed
- 2022-11-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q3 2022
A holdings report, 75 entries on the cover page, a total value of $720,456,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $720,456,000 with VALUE read as thousands by filing date, 13F file number 028-15863. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerSphera Global Healthcare Management LP028-15865
- included managerSphera Global Healthcare GP Ltd.028-15864
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| INVESCO QQQ TR | 46090E953 | PUT | 325,500 | $86,993,000 | thousands by filing date | put |
| ASTRAZENECA PLC SPONSORED ADR | 046353108 | ADR | 897,060 | $49,195,000 | thousands by filing date | |
| Eli Lilly and Company | 532457108 | COM | 143,550 | $46,417,000 | thousands by filing date | |
| SANOFI SA SPONSORED ADR | 80105N105 | ADR | 1,214,515 | $46,176,000 | thousands by filing date | |
| Johnson & Johnson | 478160104 | COM | 216,151 | $35,310,000 | thousands by filing date | |
| Merck & Co.,Inc. | 58933Y105 | COM | 367,000 | $31,606,000 | thousands by filing date | |
| NOVO-NORDISK A S ADR | 670100205 | ADR | 296,440 | $29,534,000 | thousands by filing date | |
| AbbVie,Inc. | 00287Y109 | COM | 162,285 | $21,780,000 | thousands by filing date | |
| NVIDIA CORPORATION | 67066G904 | CALL | 172,600 | $20,952,000 | thousands by filing date | call |
| SYNDAX PHARMACEUTICALS INC | 87164F105 | COM | 822,696 | $19,769,000 | thousands by filing date | |
| TEVA PHARMACEUTICAL INDS LTD | 881624909 | CALL | 2,210,000 | $17,835,000 | thousands by filing date | call |
| BIOGEN INC COM | 09062X103 | Stock | 55,500 | $14,819,000 | thousands by filing date | |
| CRINETICS PHARMACEUTICALS INC COM | 22663K107 | Stock | 626,552 | $12,305,000 | thousands by filing date | |
| UNITY SOFTWARE INC | 91332U901 | CALL | 367,500 | $11,709,000 | thousands by filing date | call |
| KURA ONCOLOGY INC COM | 50127T109 | Stock | 789,952 | $10,791,000 | thousands by filing date | |
| KEZAR LIFE SCIENCES INC | 49372L100 | COM | 1,245,806 | $10,726,000 | thousands by filing date | |
| CHINOOK THERAPEUTICS INC | 16961L106 | COM | 534,358 | $10,505,000 | thousands by filing date | |
| IVERIC BIO INC | 46583P102 | COM | 581,829 | $10,438,000 | thousands by filing date | |
| PALO ALTO NETWORKS INC | 697435105 | COM | 63,000 | $10,319,000 | thousands by filing date | |
| WIX COM LTD SHS | M98068105 | Stock | 129,000 | $10,092,000 | thousands by filing date | |
| SPRINGWORKS THERAPEUTICS INC | 85205L107 | COM | 301,625 | $8,605,000 | thousands by filing date | |
| KORNIT DIGITAL LTD | M6372Q113 | SHS | 322,926 | $8,593,000 | thousands by filing date | |
| GLOBAL-E ONLINE LTD NPV | M5216V106 | SHS | 311,460 | $8,335,000 | thousands by filing date | |
| POINT BIOPHARMA GLOBAL INC | 730541109 | COM | 1,052,842 | $8,138,000 | thousands by filing date | |
| Adobe Inc | 00724F101 | COM | 29,150 | $8,022,000 | thousands by filing date | |
| IMMATICS N.V | N44445109 | SHS | 795,406 | $7,954,000 | thousands by filing date | |
| Perion Network Ltd | M78673114 | COM | 405,184 | $7,816,000 | thousands by filing date | |
| KEROS THERAPEUTICS INC COM | 492327101 | Stock | 206,819 | $7,781,000 | thousands by filing date | |
| ALTIMMUNE INC | 02155H200 | COM NEW | 600,298 | $7,666,000 | thousands by filing date | |
| ULTRAGENYX PHARMACEUTICAL IN | 90400D108 | COM | 173,696 | $7,193,000 | thousands by filing date | |
| SENTINELONE INC | 81730H109 | CL A | 280,000 | $7,157,000 | thousands by filing date | |
| RELMADA THERAPEUTICS INC | 75955J402 | COMMON STOCK | 193,230 | $7,153,000 | thousands by filing date | |
| ALBIREO PHARMA INC | 01345P106 | COMMON STOCK | 359,000 | $6,950,000 | thousands by filing date | |
| SOLAREDGE TECHNOLOGIES INC | 83417M104 | COM | 29,426 | $6,811,000 | thousands by filing date | |
| Gilead Sciences,Inc. | 375558103 | COM | 105,090 | $6,483,000 | thousands by filing date | |
| CONCERT PHARMACEUTICALS INC | 206022105 | COM | 952,783 | $6,384,000 | thousands by filing date | |
| GENERAC HLDGS INC | 368736904 | CALL | 35,600 | $6,342,000 | thousands by filing date | call |
| MERUS N V | N5749R100 | COM | 313,326 | $6,276,000 | thousands by filing date | |
| ARCELLX INC COMMON STOCK | 03940C100 | Stock | 334,080 | $6,271,000 | thousands by filing date | |
| TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS | 881624209 | ADR | 776,346 | $6,265,000 | thousands by filing date | |
| BELLUS HEALTH INC NEW | 07987C204 | COM | 464,860 | $4,909,000 | thousands by filing date | |
| NVIDIA Corp | 67066G104 | COM | 40,000 | $4,856,000 | thousands by filing date | |
| SENTINELONE INC | 81730H909 | CALL | 164,800 | $4,212,000 | thousands by filing date | call |
| CINCOR PHARMA INC | 17240Y109 | COM | 118,950 | $3,904,000 | thousands by filing date | |
| FIVERR INTL LTD | 33835LAA3 | NOTE 11/0 | 4,951,000 | $3,900,000 | thousands by filing date | |
| 89BIO INC | 282559103 | COM | 658,784 | $3,814,000 | thousands by filing date | |
| RELMADA THERAPEUTICS INC | 75955J952 | COM | 93,000 | $3,443,000 | thousands by filing date | put |
| REZOLUTE INC | 76200L309 | COMMON STOCK | 1,155,897 | $3,167,000 | thousands by filing date | |
| INOZYME PHARMA INC | 45790W108 | COM | 1,175,058 | $3,149,000 | thousands by filing date | |
| DICE THERAPEUTICS INC | 23345J104 | COM | 152,913 | $3,101,000 | thousands by filing date | |
| DICE THERAPEUTICS INC | 23345J954 | COM | 150,000 | $3,042,000 | thousands by filing date | put |
| WEREWOLF THERAPEUTICS INC | 95075A107 | CMN | 626,810 | $2,827,000 | thousands by filing date | |
| RIGEL PHARMACEUTICALS INC | 766559603 | COMMON STOCK | 2,162,586 | $2,552,000 | thousands by filing date | |
| PMV PHARMACEUTICALS INC | 69353Y103 | COM | 187,800 | $2,235,000 | thousands by filing date | |
| STOKE THERAPEUTICS INC | 86150R107 | COM | 157,200 | $2,018,000 | thousands by filing date | |
| SUNRUN INC | 86771W105 | COM | 65,000 | $1,793,000 | thousands by filing date | |
| INFINITY PHARMACEUTICALS INC | 45665G303 | COM | 1,476,000 | $1,756,000 | thousands by filing date | |
| ALPINE IMMUNE SCIENCES INC | 02083G100 | COM | 200,000 | $1,440,000 | thousands by filing date | |
| ALTIMMUNE INC | 02155H950 | COM NEW | 100,000 | $1,277,000 | thousands by filing date | put |
| MAGIC SOFTWARE ENTERPRISES LTD ORD | 559166103 | Stock | 81,293 | $1,265,000 | thousands by filing date | |
| VERONA PHARMA PLC | 925050106 | SPONSORED ADS | 120,000 | $1,226,000 | thousands by filing date | |
| POSEIDA THERAPEUTICS INC | 73730P108 | COM | 300,000 | $1,059,000 | thousands by filing date | |
| MEDIWOUND LTD | M68830104 | ORD SHS | 688,716 | $958,000 | thousands by filing date | |
| ICL GROUP LTD SHS | M53213100 | Stock | 111,482 | $912,000 | thousands by filing date | |
| NICE LTD SPONSORED ADR | 653656108 | ADR | 3,145 | $592,000 | thousands by filing date | |
| WIX COM LTD | 92940WAD1 | NOTE 8/1 | 700,000 | $591,000 | thousands by filing date | |
| EDGEWISE THERAPEUTICS INC | 28036F105 | COM | 60,000 | $590,000 | thousands by filing date | |
| NICE SYS INC | 65366HAB9 | BOND | 250,000 | $571,000 | thousands by filing date | |
| ONCORUS INC | 68236R103 | COM | 540,258 | $459,000 | thousands by filing date | |
| UNITY SOFTWARE INC COM | 91332U101 | Stock | 11,500 | $366,000 | thousands by filing date | |
| CYCLACEL PHARMACE 6percent PFDCONV | 23254L603 | Stock | 250,000 | $365,000 | thousands by filing date | |
| IMMATICS N.V | N44445117 | *W EXP 07/01/202 | 100,000 | $271,000 | thousands by filing date | |
| ARBE ROBOTICS LTD ORDINARY SHARES | M1R95N100 | Stock | 43,165 | $259,000 | thousands by filing date | |
| OTONOMO TECHNOLOGIES LTD | M7571L103 | ORDINARY SHARES | 391,863 | $111,000 | thousands by filing date |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001496201-22-000008 | this filing | 2022-11-14 | acceptance time not in the bulk data set |