13F-HR filed by SPHERA FUNDS MANAGEMENT LTD.
SPHERA FUNDS MANAGEMENT LTD. filed this 13F-HR for the quarter ended 2022-03-31, filed 2022-05-16, with 66 holding rows worth $707,568,000.
- Accession
- 0001496201-22-000004
- Filer
- CIK 1496201
- Filed
- 2022-05-16
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q1 2022
A holdings report, 66 entries on the cover page, a total value of $707,568,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $707,568,000 with VALUE read as thousands by filing date, 13F file number 028-15863. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerSphera Global Healthcare Management LP028-15865
- included managerSphera Global Healthcare GP Ltd.028-15864
- included managerSphera Healthcare US Inc.028-21415
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| ASTRAZENECA PLC SPONSORED ADR | 046353108 | ADR | 836,817 | $55,514,000 | thousands by filing date | |
| Johnson & Johnson | 478160104 | COM | 295,023 | $52,287,000 | thousands by filing date | |
| SANOFI SA SPONSORED ADR | 80105N105 | ADR | 972,415 | $49,924,000 | thousands by filing date | |
| INVESCO QQQ TR | 46090E103 | COM | 126,000 | $45,680,000 | thousands by filing date | put |
| AbbVie,Inc. | 00287Y109 | COM | 190,994 | $30,962,000 | thousands by filing date | |
| FIVE9 INC | 338307101 | COM | 248,900 | $27,479,000 | thousands by filing date | call |
| Pfizer Inc. | 717081103 | COM | 515,070 | $26,665,000 | thousands by filing date | |
| NOVO-NORDISK A S ADR | 670100205 | ADR | 237,400 | $26,363,000 | thousands by filing date | |
| SPRINGWORKS THERAPEUTICS INC | 85205L107 | COM | 460,025 | $25,964,000 | thousands by filing date | |
| Merck & Co.,Inc. | 58933Y105 | COM | 278,200 | $22,826,000 | thousands by filing date | |
| SYNDAX PHARMACEUTICALS INC | 87164F105 | COM | 1,277,413 | $22,201,000 | thousands by filing date | |
| Eli Lilly and Company | 532457108 | COM | 70,295 | $20,130,000 | thousands by filing date | |
| TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS | 881624209 | ADR | 1,890,000 | $17,747,000 | thousands by filing date | call |
| BIOMARIN PHARMACEUTICAL INC | 09061G101 | COM | 211,326 | $16,293,000 | thousands by filing date | |
| KYMERA THERAPEUTICS INC | 501575104 | COM | 368,061 | $15,576,000 | thousands by filing date | |
| IVERIC BIO INC | 46583P102 | COM | 774,130 | $13,029,000 | thousands by filing date | |
| GENERAC HLDGS INC | 368736104 | COM | 42,211 | $12,548,000 | thousands by filing date | |
| CRINETICS PHARMACEUTICALS INC COM | 22663K107 | Stock | 521,947 | $11,457,000 | thousands by filing date | |
| Advanced Micro Devices,Inc. | 007903107 | COM | 100,000 | $10,934,000 | thousands by filing date | |
| MERUS N V | N5749R100 | COM | 409,141 | $10,818,000 | thousands by filing date | |
| ZIM INTEGRATED SHIPPING SERV | M9T951109 | SHS | 148,000 | $10,761,000 | thousands by filing date | |
| KURA ONCOLOGY INC COM | 50127T109 | Stock | 618,244 | $9,941,000 | thousands by filing date | |
| C4 THERAPEUTICS INC | 12529R107 | COM STK | 362,528 | $8,795,000 | thousands by filing date | |
| CHINOOK THERAPEUTICS INC | 16961L106 | COM | 493,677 | $8,077,000 | thousands by filing date | |
| ALTIMMUNE INC | 02155H200 | COM NEW | 1,306,953 | $7,959,000 | thousands by filing date | |
| RELMADA THERAPEUTICS INC | 75955J402 | COMMON STOCK | 291,252 | $7,861,000 | thousands by filing date | |
| TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS | 881624209 | ADR | 832,878 | $7,821,000 | thousands by filing date | |
| KEROS THERAPEUTICS INC COM | 492327101 | Stock | 139,581 | $7,590,000 | thousands by filing date | |
| SPRINGWORKS THERAPEUTICS INC | 85205L107 | COM | 125,000 | $7,055,000 | thousands by filing date | call |
| SUNRUN INC | 86771W105 | COM | 228,000 | $6,924,000 | thousands by filing date | call |
| Perion Network Ltd | M78673114 | COM | 306,051 | $6,883,000 | thousands by filing date | |
| IMMUNIC INC | 4525EP101 | COM | 583,206 | $6,590,000 | thousands by filing date | |
| VISTAGEN THERAPEUTICS INC | 92840H202 | COM | 4,951,423 | $6,140,000 | thousands by filing date | |
| Visa Inc | 92826C839 | COM | 25,200 | $5,589,000 | thousands by filing date | |
| Airbnb, Inc. Class A | 009066101 | COM | 30,000 | $5,153,000 | thousands by filing date | |
| IMMATICS N.V | N44445109 | SHS | 621,925 | $4,969,000 | thousands by filing date | |
| SUNRUN INC | 86771W105 | COM | 150,000 | $4,556,000 | thousands by filing date | |
| CAESARSTONE LTD | M20598104 | ORD SHS | 428,046 | $4,503,000 | thousands by filing date | |
| MasterCard, Inc | 57636Q104 | COM | 12,100 | $4,324,000 | thousands by filing date | |
| FIVERR INTL LTD | 33835LAA3 | NOTE 11/0 | 4,951,000 | $4,227,000 | thousands by filing date | |
| AIRBNB INC | 009066901 | CALL | 24,300 | $4,174,000 | thousands by filing date | call |
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 24,768 | $4,044,000 | thousands by filing date | |
| NAUTILUS BIOTECHNOLOGY INC | 63909J108 | COM | 840,000 | $3,646,000 | thousands by filing date | |
| REPLIMUNE GROUP INC | 76029N106 | COMMON STOCK | 212,640 | $3,611,000 | thousands by filing date | |
| FATE THERAPEUTICS INC | 31189P102 | COM | 89,425 | $3,467,000 | thousands by filing date | |
| VERONA PHARMA PLC | 925050106 | SPONSORED ADS | 666,339 | $3,325,000 | thousands by filing date | |
| FIVE9 INC | 338307101 | COM | 29,699 | $3,279,000 | thousands by filing date | |
| KEZAR LIFE SCIENCES INC | 49372L100 | COM | 187,599 | $3,118,000 | thousands by filing date | |
| ASCENDIS PHARMA A/S DKK 1.0 AD | 04351P101 | SPONSORED ADR | 26,529 | $3,113,000 | thousands by filing date | |
| IRONSOURCE LTD NPV | M5R75Y101 | CL A ORD SHS | 620,000 | $2,976,000 | thousands by filing date | |
| VINCERX PHARMA INC | 92731L106 | COM NEW | 720,161 | $2,881,000 | thousands by filing date | |
| Caterpillar Inc. | 149123101 | COM | 12,000 | $2,674,000 | thousands by filing date | |
| WEREWOLF THERAPEUTICS INC | 95075A107 | CMN | 584,203 | $2,570,000 | thousands by filing date | |
| SENTINELONE INC | 81730H109 | CL A | 65,000 | $2,518,000 | thousands by filing date | |
| TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS | 881624209 | ADR | 210,000 | $1,972,000 | thousands by filing date | put |
| KRYSTAL BIOTECH INC COM | 501147102 | Stock | 25,310 | $1,684,000 | thousands by filing date | |
| CYCLACEL PHARMACE 6percent PFDCONV | 23254L603 | Stock | 508,322 | $1,550,000 | thousands by filing date | |
| MAGIC SOFTWARE ENTERPRISES LTD ORD | 559166103 | Stock | 81,293 | $1,401,000 | thousands by filing date | |
| LIANBIO ADR | 53000N108 | COM | 275,007 | $1,020,000 | thousands by filing date | |
| AYALA PHARMACEUTICALS INC | 05465V108 | COM | 250,000 | $995,000 | thousands by filing date | |
| ONCORUS INC | 68236R103 | COM | 540,258 | $962,000 | thousands by filing date | |
| OTONOMO TECHNOLOGIES LTD | M7571L103 | ORDINARY SHARES | 391,863 | $772,000 | thousands by filing date | |
| NICE SYS INC | 65366HAB9 | BOND | 250,000 | $662,000 | thousands by filing date | |
| TEADS HLDG CO | 69002R103 | COM | 52,531 | $564,000 | thousands by filing date | |
| ARBE ROBOTICS LTD ORDINARY SHARES | M1R95N100 | Stock | 43,165 | $300,000 | thousands by filing date | |
| IMMATICS N.V | N44445117 | *W EXP 07/01/202 | 100,000 | $175,000 | thousands by filing date |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001496201-22-000004 | this filing | 2022-05-16 | acceptance time not in the bulk data set |