13F-HR filed by RTW INVESTMENTS, LP
RTW INVESTMENTS, LP filed this 13F-HR for the quarter ended 2022-03-31, filed 2022-05-16, with 106 holding rows worth $4,831,643,000.
- Accession
- 0001493152-22-013567
- Filer
- CIK 1493215
- Filed
- 2022-05-16
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q1 2022
A holdings report, 106 entries on the cover page, a total value of $4,831,643,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $4,831,643,000 with VALUE read as thousands by filing date, 13F file number 028-16670. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerRTW MASTER FUND, LTD.028-16671
- included managerRTW Innovation Master Fund Ltd.028-19525
- included managerRTW Venture Fund Ltd028-19571
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 1,683,362 | $274,876,000 | thousands by filing date | |
| ROCKET PHARMACEUTICALS INC | 77313F106 | COM | 15,802,802 | $250,632,000 | thousands by filing date | |
| Thermo Fisher Scientific Inc. | 883556102 | COM | 373,000 | $220,312,000 | thousands by filing date | |
| PTC THERAPEUTICS INC | 69366J200 | COM | 5,221,228 | $194,804,000 | thousands by filing date | |
| ILLUMINA INC | 452327109 | COM | 509,375 | $177,976,000 | thousands by filing date | |
| MASIMO CORP COM | 574795100 | Stock | 1,127,593 | $164,110,000 | thousands by filing date | |
| ESTABLISHMENT LABS HOLDINGS | G31249108 | COMMON STOCK | 2,319,138 | $156,287,000 | thousands by filing date | |
| VERICEL CORP | 92346J108 | COM | 4,017,570 | $153,552,000 | thousands by filing date | |
| PENUMBRA INC COM | 70975L107 | Stock | 665,871 | $147,910,000 | thousands by filing date | |
| MIRATI THERAPEUTICS INC | 60468T105 | COM | 1,561,497 | $128,386,000 | thousands by filing date | |
| GLOBUS MED INC CL A | 379577208 | Stock | 1,682,291 | $124,119,000 | thousands by filing date | |
| TANDEM DIABETES CARE INC | 875372203 | COM NEW | 1,004,936 | $116,864,000 | thousands by filing date | |
| PROTAGONIST THERAPEUTICS | 74366E102 | COM | 4,794,499 | $113,534,000 | thousands by filing date | |
| C4 THERAPEUTICS INC | 12529R107 | COM STK | 4,531,982 | $109,946,000 | thousands by filing date | |
| AXONICS INC | 05465P101 | COM | 1,743,864 | $109,166,000 | thousands by filing date | |
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 336,978 | $106,253,000 | thousands by filing date | |
| CUTERA INC | 232109108 | COM | 1,526,263 | $105,312,000 | thousands by filing date | |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 3,084,215 | $105,048,000 | thousands by filing date | |
| PROMETHEUS BIOSCIENCES INC | 74349U108 | COM | 2,757,947 | $104,140,000 | thousands by filing date | |
| ULTRAGENYX PHARMACEUTICAL IN | 90400D108 | COM | 1,373,284 | $99,728,000 | thousands by filing date | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 2,561,182 | $94,277,000 | thousands by filing date | |
| AVIDITY BIOSCIENCES INC COM | 05370A108 | Stock | 4,795,000 | $88,564,000 | thousands by filing date | |
| FULCRUM THERAPEUTICS INC | 359616109 | COMMON STOCK | 3,611,194 | $85,405,000 | thousands by filing date | |
| PMV PHARMACEUTICALS INC | 69353Y103 | COM | 3,872,154 | $80,618,000 | thousands by filing date | |
| NATERA INC COM | 632307104 | Stock | 1,917,283 | $77,995,000 | thousands by filing date | |
| STOKE THERAPEUTICS INC | 86150R107 | COM | 3,644,248 | $76,711,000 | thousands by filing date | |
| RELMADA THERAPEUTICS INC | 75955J402 | COMMON STOCK | 2,540,074 | $68,557,000 | thousands by filing date | |
| AXSOME THERAPEUTICS INC. COM | 05464T104 | Stock | 1,618,819 | $67,003,000 | thousands by filing date | |
| REGENXBIO INC | 75901B107 | COM | 1,845,366 | $61,248,000 | thousands by filing date | |
| ADICET BIO INC | 007002108 | COM | 2,989,482 | $59,700,000 | thousands by filing date | |
| BICYCLE THERAPEUTICS PLC-ADR | 088786108 | SPONSORED ADS | 1,276,276 | $56,003,000 | thousands by filing date | |
| 10X GENOMICS INC CL A COM | 88025U109 | Stock | 734,481 | $55,872,000 | thousands by filing date | |
| IMMUNOCORE HLDGS PLC ADS | 45258D105 | ADR | 1,859,471 | $55,598,000 | thousands by filing date | |
| DERMTECH INC | 24984K105 | COM | 3,118,666 | $45,782,000 | thousands by filing date | |
| GUARDANT HEALTH INC COM | 40131M109 | Stock | 689,887 | $45,698,000 | thousands by filing date | |
| OUTSET MEDICAL INC | 690145107 | COM | 899,652 | $40,844,000 | thousands by filing date | |
| GH RESEARCH PLC ORDINARY SHARES | G3855L106 | Stock | 2,168,957 | $39,670,000 | thousands by filing date | |
| AVADEL PHARMACEUTICALS, PLC | 05337M104 | COMMON STOCK-FO | 5,741,939 | $39,217,000 | thousands by filing date | |
| QUANTERIX CORP | 74766Q101 | COMMON STOCK | 1,248,517 | $36,444,000 | thousands by filing date | |
| MACROGENICS INC | 556099109 | COM | 3,975,554 | $35,025,000 | thousands by filing date | |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 2,013,601 | $33,869,000 | thousands by filing date | |
| JOUNCE THERAPEUTICS INC | 481116101 | COM | 4,680,412 | $31,780,000 | thousands by filing date | |
| IMMUNIC INC | 4525EP101 | COM | 2,705,513 | $30,572,000 | thousands by filing date | |
| TENAYA THERAPEUTICS INC | 87990A106 | COM | 2,458,750 | $28,964,000 | thousands by filing date | |
| Milestone Pharmaceuticals Inc | 59935V107 | COM | 4,315,102 | $27,703,000 | thousands by filing date | |
| ATHIRA PHARMA INC | 04746L104 | COM | 1,906,557 | $25,739,000 | thousands by filing date | |
| CINCOR PHARMA INC | 17240Y109 | COM | 1,389,705 | $24,375,000 | thousands by filing date | |
| OYSTER POINT PHARMA INC | 69242L106 | COMMON STOCK | 2,058,504 | $23,961,000 | thousands by filing date | |
| CASTLE BIOSCIENCES INC | 14843C105 | COMMON STOCK | 496,675 | $22,281,000 | thousands by filing date | |
| APYX MEDICAL CORPORATION | 03837C106 | COM | 3,398,279 | $22,191,000 | thousands by filing date | |
| SCIENCE 37 HOLDINGS INC | 808644108 | COM | 4,039,341 | $21,610,000 | thousands by filing date | |
| Ventyx Biosciences Inc | 92332V107 | Common Stock | 1,551,778 | $21,058,000 | thousands by filing date | |
| 2SEVENTY BIO INC COMMON STOCK | 901384107 | Stock | 1,229,508 | $20,975,000 | thousands by filing date | |
| PULMONX CORP | 745848101 | COM | 798,255 | $19,805,000 | thousands by filing date | |
| OLINK HLDG AB | 680710100 | ADR | 1,018,188 | $17,981,000 | thousands by filing date | |
| MONTE ROSA THERAPEUTICS INC | 61225M102 | COM | 1,214,572 | $17,028,000 | thousands by filing date | |
| ESSA PHARMA INC | 29668H708 | COM NEW | 2,637,192 | $16,298,000 | thousands by filing date | |
| ITEOS THERAPEUTICS INC | 46565G104 | COM | 489,014 | $15,736,000 | thousands by filing date | |
| CYTOMX THERAPEUTICS INC | 23284F105 | COMMON STOCK | 5,779,700 | $15,432,000 | thousands by filing date | |
| NANOSTRING TECHNOLOGIES INC | 63009R109 | COM | 404,029 | $14,040,000 | thousands by filing date | |
| BRAINSWAY LTD | 10501L106 | CMN | 1,602,381 | $13,989,000 | thousands by filing date | |
| WHITEHAWK THERAPEUTICS INC | 00032Q104 | CMN | 764,701 | $12,977,000 | thousands by filing date | |
| RENOVACOR INC | 75989E106 | COM | 3,000,803 | $12,723,000 | thousands by filing date | |
| TELA BIO INC | 872381108 | COM | 1,017,546 | $11,834,000 | thousands by filing date | |
| SIGHT SCIENCES INC | 82657M105 | COMMON STOCK | 997,099 | $11,526,000 | thousands by filing date | |
| LA JOLLA PHARMACEUTICAL CO | 503459604 | COM PAR $.0001 2 | 2,327,403 | $9,938,000 | thousands by filing date | |
| AGENUS INC | 00847G705 | COM NEW | 3,582,481 | $8,813,000 | thousands by filing date | |
| PYXIS ONCOLOGY INC COMMON STOCK | 747324101 | Stock | 2,120,760 | $8,568,000 | thousands by filing date | |
| EXAGEN INC | 30068X103 | COM | 990,143 | $7,951,000 | thousands by filing date | |
| UROGEN PHARMA LTD | M96088105 | COMMON STOCK | 857,464 | $7,469,000 | thousands by filing date | |
| NYXOAH S A | B6S7WD106 | SHS | 344,911 | $6,602,000 | thousands by filing date | |
| PROQR THERAPEUTICS NV | N71542109 | SHS EURO | 7,019,610 | $6,354,000 | thousands by filing date | |
| LANDOS BIOPHARMA INC | 515069102 | CMN | 4,275,722 | $6,307,000 | thousands by filing date | |
| RESEARCH ALLIANCE CORP II | 760873109 | CMN | 637,000 | $6,217,000 | thousands by filing date | |
| BCLS ACQUISITION CORP | G0904B105 | CMN | 612,500 | $6,045,000 | thousands by filing date | |
| PROCEPT BIOROBOTICS CORP COM | 74276L105 | Stock | 161,138 | $5,638,000 | thousands by filing date | |
| ARYA SCIENCES ACQU CORP IV | G31659108 | COM | 500,000 | $4,900,000 | thousands by filing date | |
| SUMMIT HEALTHCRE ACQUISTN CO | G8566R128 | UNIT 06/03/2026 | 500,000 | $4,889,000 | thousands by filing date | |
| ARYA SCIENCES ACQUISITN CORP | G31658100 | CLASS A ORD SHS | 500,000 | $4,855,000 | thousands by filing date | |
| NAUTILUS BIOTECHNOLOGY INC | 63909J108 | COM | 1,100,000 | $4,774,000 | thousands by filing date | |
| ROIVANT SCIENCES LTD | G76279101 | SHS | 802,717 | $3,965,000 | thousands by filing date | |
| POINT BIOPHARMA GLOBAL INC | 730541109 | COM | 490,000 | $3,905,000 | thousands by filing date | |
| 5 01 ACQUISITION CORP | 33836P105 | CMN | 392,000 | $3,861,000 | thousands by filing date | |
| Johnson & Johnson | 478160104 | COM | 18,127 | $3,213,000 | thousands by filing date | |
| MEDICUS SCIENCES ACQUISITION | G5960S108 | CL A SHS | 300,000 | $2,934,000 | thousands by filing date | |
| ASLAN PHARMACEUTICALS LTD | 04522R101 | ADR | 3,250,000 | $2,924,000 | thousands by filing date | |
| IMMATICS N.V | N44445109 | SHS | 350,000 | $2,797,000 | thousands by filing date | |
| GENETRON HLDGS LTD | 37186H100 | ADS | 1,198,961 | $2,626,000 | thousands by filing date | |
| APELLIS PHARMACEUTICALS INC | 03753U106 | COM | 51,194 | $2,601,000 | thousands by filing date | |
| RXSIGHT INC | 78349D107 | COM | 150,000 | $1,857,000 | thousands by filing date | |
| SOPHIA GENETICS SA | H82027105 | ORDINARY SHARES | 226,589 | $1,752,000 | thousands by filing date | |
| APOLLO ENDOSURGERY INC | 03767D108 | COM | 258,064 | $1,561,000 | thousands by filing date | |
| MAXCYTE INC | 57777K106 | COM | 199,567 | $1,395,000 | thousands by filing date | |
| CONNECT BIOPHARMA HLDGS LTD | 207523101 | SHS | 446,564 | $1,349,000 | thousands by filing date | |
| ISOPLEXIS CORP | 465005106 | COM | 365,000 | $1,252,000 | thousands by filing date | |
| MIROMATRIX MED INC | 60471P108 | COM | 280,000 | $1,109,000 | thousands by filing date | |
| CODEX DNA INC | 192003101 | COM | 200,000 | $1,074,000 | thousands by filing date | |
| AVITA THERAPEUTICS, INC. | 05380C102 | COM | 106,667 | $905,000 | thousands by filing date | |
| AKOYA BIOSCIENCES INC COM | 00974H104 | Stock | 77,676 | $854,000 | thousands by filing date | |
| 908 DEVICES INC COM | 65443P102 | Stock | 40,000 | $760,000 | thousands by filing date | |
| MINERVA SURGICAL INC | 60343F106 | COM | 166,000 | $747,000 | thousands by filing date | |
| SINGULAR GENOMICS SYSTEMS IN | 82933R100 | COM | 100,000 | $631,000 | thousands by filing date | |
| Adverum Biotechnologies, Inc. | 00773U108 | Common Stock | 223,725 | $293,000 | thousands by filing date | |
| ZYMERGEN INC | 98985X100 | COM | 70,000 | $202,000 | thousands by filing date | |
| Renovacor Inc | 75989E114 | Warrant | 350,000 | $109,000 | thousands by filing date | |
| MEDICUS SCIENCES ACQUISITION | G5960S124 | *W EXP 02/12/202 | 33,331 | $14,000 | thousands by filing date |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001493152-22-013567 | this filing | 2022-05-16 | acceptance time not in the bulk data set |