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13F-HR filed by RTW INVESTMENTS, LP

RTW INVESTMENTS, LP filed this 13F-HR for the quarter ended 2020-12-31, filed 2021-02-16, with 102 holding rows worth $5,960,261,000.

Accession
0001493152-21-003922
Filed
2021-02-16
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2020

A holdings report, 102 entries on the cover page, a total value of $5,960,261,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $5,960,264,000 with VALUE read as thousands by filing date, 13F file number 028-16670. The quarter's positions are built on this report. The resolved quarter.

Other managers

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
ROCKET PHARMACEUTICALS INC77313F106COM17,060,211$935,582,000thousands by filing date
IMMUNOVANT INC45258J102COM7,592,253$350,686,000thousands by filing date
PTC THERAPEUTICS INC69366J200COM4,221,836$257,659,000thousands by filing date
MIRATI THERAPEUTICS INC60468T105COM1,054,364$231,581,000thousands by filing date
STOKE THERAPEUTICS INC86150R107COM3,544,248$219,495,000thousands by filing date
ALNYLAM PHARMACEUTICALS INC COM02043Q107Stock1,681,645$218,563,000thousands by filing date
NATERA INC COM632307104Stock1,712,234$170,402,000thousands by filing date
DICERNA PHARMACEUTICALS INC253031108COM7,253,857$159,802,000thousands by filing date
ARVINAS INC04335A105COM1,790,996$152,109,000thousands by filing date
VERICEL CORP92346J108COM4,517,570$139,503,000thousands by filing date
AXSOME THERAPEUTICS INC. COM05464T104Stock1,672,416$136,252,000thousands by filing date
ILLUMINA INC452327109COM361,778$133,858,000thousands by filing date
CERNER CORP156782104COM1,701,680$133,548,000thousands by filing date
MASIMO CORP COM574795100Stock469,416$125,982,000thousands by filing date
GLOBUS MED INC CL A379577208Stock1,640,859$107,017,000thousands by filing date
AVIDITY BIOSCIENCES INC COM05370A108Stock3,995,000$101,952,000thousands by filing date
TARSUS PHARMACEUTICALS INC87650L103COMMON STOCK2,463,601$98,987,000thousands by filing date
AXONICS INC05465P101COM1,883,864$94,042,000thousands by filing date
DERMTECH INC24984K105COM2,887,215$93,661,000thousands by filing date
10X GENOMICS INC CL A COM88025U109Stock660,933$93,588,000thousands by filing date
ATHIRA PHARMA INC04746L104COM2,685,779$88,899,000thousands by filing date
ESTABLISHMENT LABS HOLDINGSG31249108COMMON STOCK2,319,138$87,292,000thousands by filing date
FREQUENCY THERAPEUTICS INC35803L108COM2,461,486$86,792,000thousands by filing date
Adverum Biotechnologies, Inc.00773U108Common Stock7,227,364$78,345,000thousands by filing date
GUARDANT HEALTH INC COM40131M109Stock581,970$75,004,000thousands by filing date
PULMONX CORP745848101COM1,129,600$74,839,000thousands by filing date
PROTAGONIST THERAPEUTICS74366E102COM3,650,069$73,585,000thousands by filing date
C4 THERAPEUTICS INC12529R107COM STK2,149,228$68,679,000thousands by filing date
TANDEM DIABETES CARE INC875372203COM NEW660,982$63,243,000thousands by filing date
CELLDEX THERAPEUTICS INC NEW15117B202COM NEW3,422,855$59,968,000thousands by filing date
KURA ONCOLOGY INC COM50127T109Stock1,701,781$55,580,000thousands by filing date
TRANSLATE BIO INC.89374L104Common Stock2,978,427$54,892,000thousands by filing date
NANOSTRING TECHNOLOGIES INC63009R109COM804,029$53,773,000thousands by filing date
CASTLE BIOSCIENCES INC14843C105COMMON STOCK799,009$53,653,000thousands by filing date
RELMADA THERAPEUTICS INC75955J402COMMON STOCK1,512,673$48,511,000thousands by filing date
IVERIC BIO INC46583P102COM6,722,624$46,453,000thousands by filing date
FIVE PRIME THERAPEUTICS INC.33830X104Common Stock2,515,788$42,794,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW2,000,000$41,311,000thousands by filing date
AGENUS INC00847G705COM NEW12,864,677$40,910,000thousands by filing date
OYSTER POINT PHARMA INC69242L106COMMON STOCK1,925,594$36,240,000thousands by filing date
AVADEL PHARMACEUTICALS, PLC05337M104COMMON STOCK-FO5,387,513$35,989,000thousands by filing date
ITEOS THERAPEUTICS INC46565G104COM1,074,166$35,975,000thousands by filing date
OUTSET MEDICAL INC690145107COM585,074$33,256,000thousands by filing date
TRILLIUM THERAPEUTICS INC COM NEW89620X506Stock2,165,197$31,850,000thousands by filing date
PMV PHARMACEUTICALS INC69353Y103COM500,882$30,809,000thousands by filing date
CURIS INC231269200COM3,727,360$30,527,000thousands by filing date
BERKELEY LTS INC084310101COM324,734$29,034,000thousands by filing date
Milestone Pharmaceuticals Inc59935V107COM4,315,102$28,911,000thousands by filing date
MACROGENICS INC556099109COM1,256,409$28,722,000thousands by filing date
IDEAYA BIOSCIENCES INC COM45166A102Stock1,846,843$25,856,000thousands by filing date
MIMEDX GROUP INC602496101COM2,700,320$24,519,000thousands by filing date
APYX MEDICAL CORPORATION03837C106COM3,391,279$24,417,000thousands by filing date
FULCRUM THERAPEUTICS INC359616109COMMON STOCK2,071,409$24,256,000thousands by filing date
Johnson & Johnson478160104COM149,761$23,569,000thousands by filing date
Arbutus Biopharma Corp03879J100Common Shares, without par value5,978,355$21,223,000thousands by filing date
PROQR THERAPEUTICS NVN71542109SHS EURO5,009,768$21,041,000thousands by filing date
TELA BIO INC872381108COM1,383,816$20,813,000thousands by filing date
PENUMBRA INC COM70975L107Stock118,273$20,698,000thousands by filing date
ODONATE THERAPEUTICS INC676079106COM1,000,139$19,203,000thousands by filing date
EXAGEN INC30068X103COM1,250,131$16,502,000thousands by filing date
BELLUS HEALTH INC NEW07987C204COM5,189,862$15,778,000thousands by filing date
IMMUNIC INC4525EP101COM920,814$14,079,000thousands by filing date
ACUTUS MED INC005111109COM451,834$13,017,000thousands by filing date
REGENXBIO INC75901B107COM282,260$12,803,000thousands by filing date
GENMARK DIAGNOSTICS INC372309104COM762,994$11,140,000thousands by filing date
CLEARSIDE BIOMEDICAL INC185063104COM3,958,130$10,845,000thousands by filing date
APTEVO THERAPEUTICS INC03835L207COMMON288,236$10,564,000thousands by filing date
VINCERX PHARMA INC92731L106COM NEW500,000$10,455,000thousands by filing date
CYTOMX THERAPEUTICS INC23284F105COMMON STOCK1,527,352$10,004,000thousands by filing date
ARGENX SE SPONSORED ADR04016X101ADR31,752$9,338,000thousands by filing date
LA JOLLA PHARMACEUTICAL CO503459604COM PAR $.0001 22,397,378$9,302,000thousands by filing date
MOONLAKE IMMUNOTHERAPEUTICSG4444C102COM750,000$8,528,000thousands by filing date
BRAINSWAY LTD10501L106CMN1,103,474$8,320,000thousands by filing date
CEREVEL THERAPEUTICS HLDNG I15678U128COM500,000$8,290,000thousands by filing date
SCHOLAR ROCK HLDG CORP80706P103COM166,183$8,065,000thousands by filing date
LIFESCI ACQUISITION II CORP53229E103COM650,000$6,936,000thousands by filing date
BCTG ACQUISITION CORP05492W103COM600,000$6,864,000thousands by filing date
BCLS ACQUISITION CORPG0904B105CMN612,500$6,823,000thousands by filing date
THERAPEUTICS ACQUISITION COR88339T103COM CL A490,000$6,821,000thousands by filing date
INMODE LTD SHSM5425M103Stock124,999$5,935,000thousands by filing date
ARYA SCIENCES ACQUISITION COG3166W106COM CL A500,000$5,425,000thousands by filing date
PERSONALIS INC71535D106COMMON STOCK127,501$4,668,000thousands by filing date
ITAMAR MED LTD SPONSORED ADS465437101ADR228,609$4,540,000thousands by filing date
5 01 ACQUISITION CORP33836P105CMN392,000$3,987,000thousands by filing date
BIOMX INC09090D103COM600,000$3,828,000thousands by filing date
PANACEA ACQUISITION CORP698102209UNIT 99/99/9999300,000$3,828,000thousands by filing date
IMMATICS N.VN44445109SHS350,000$3,777,000thousands by filing date
CHARDAN HEALTHCR ACQSTN 2 CO15957T206UNIT 99/99/9999350,000$3,707,000thousands by filing date
TWIST BIOSCIENCE CORP90184D100COM18,473$2,610,000thousands by filing date
BIODESIX INC09075X108COM125,000$2,520,000thousands by filing date
PROFOUND MED CORP74319B502COM NEW122,098$2,510,000thousands by filing date
908 DEVICES INC COM65443P102Stock40,000$2,278,000thousands by filing date
MARAVAI LIFESCIENCES HLDGS A56600D107COMMON STOCK70,000$1,964,000thousands by filing date
ORASURE TECHNOLOGIES INC68554V108COM184,000$1,948,000thousands by filing date
ELUTIA INC05479K106CL A COM125,000$1,704,000thousands by filing date
VINCERX PHARMA INC92731L114*W EXP 12/24/202500,000$1,650,000thousands by filing date
CEREVEL THERAPEUTICS HLDNG I15678U102*W EXP 06/09/202166,666$942,000thousands by filing date
BURNING ROCK BIOTECH LTD12233L107SPONSORED ADS30,000$693,000thousands by filing date
BIORA THERAPEUTICS INC74319F107COM100,000$531,000thousands by filing date
BIOMX INC09090D111*W EXP 10/28/202600,000$480,000thousands by filing date
BIOATLA INC09077B104COM10,000$340,000thousands by filing date
SEER INC81578P106COM CL A4,000$225,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001493152-21-003922this filing2021-02-16acceptance time not in the bulk data set