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13F-HR filed by SIMPLEX TRADING, LLC

SIMPLEX TRADING, LLC filed this 13F-HR for the quarter ended 2022-03-31, filed 2022-05-02, with 10,642 holding rows worth $109,361,898,000.

Accession
0001488542-22-000006
Filed
2022-05-02
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q1 2022

A holdings report, 11,560 entries on the cover page, a total value of $109,361,898,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $109,356,144,000 with VALUE read as thousands by filing date, 13F file number 028-16834. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
VICINITY MOTOR CORP925654955PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
LEJU HLDGS LTD50187J108SPONSORED ADS432$0thousands by filing dateValue filed as zero, left out of ratios.
APPLIED DNA SCIENCES INC03815U300COMMON76$0thousands by filing dateValue filed as zero, left out of ratios.
TITAN PHARMACEUTICALS INC DE888314606COMMON354$0thousands by filing dateValue filed as zero, left out of ratios.
EVAXION BIOTECH A S29970R105ADR55$0thousands by filing dateValue filed as zero, left out of ratios.
ARC DOCUMENT SOLUTIONS INC00191G953COM200$0thousands by filing dateputValue filed as zero, left out of ratios.
ELOXX PHARMACEUTICALS INC29014R103COM764$0thousands by filing dateValue filed as zero, left out of ratios.
NEPTUNE WELLNESS SOLUTIONS I64079L105COM2,669$0thousands by filing dateValue filed as zero, left out of ratios.
IBIO INC451033203COM NEW100$0thousands by filing dateValue filed as zero, left out of ratios.
ONCOSEC MED INC68234L306COM6$0thousands by filing dateValue filed as zero, left out of ratios.
TREVENA INC89532E109COM200$0thousands by filing dateValue filed as zero, left out of ratios.
GLOBAL X FDS37954Y723EDUCATION ETF81$0thousands by filing dateValue filed as zero, left out of ratios.
SOLENO THERAPEUTIVS, INC.834203200COMM156$0thousands by filing dateValue filed as zero, left out of ratios.
Benitec Biopharma, Inc.08205P100common100$0thousands by filing dateValue filed as zero, left out of ratios.
FNCB BANCORP INC302578909CALL600$0thousands by filing datecallValue filed as zero, left out of ratios.
BURGERFI INTERNATIONAL INC12122L951PUT200$0thousands by filing dateputValue filed as zero, left out of ratios.
QUANTUM CORP747906951PUT400$0thousands by filing dateputValue filed as zero, left out of ratios.
AGILE THERAPEUTICS INC00847L100COM265$0thousands by filing dateValue filed as zero, left out of ratios.
ALPINE IMMUNE SCIENCES INC02083G950COM100$0thousands by filing dateputValue filed as zero, left out of ratios.
ACER THERAPEUTICS INC00444P108CMN242$0thousands by filing dateValue filed as zero, left out of ratios.
CIDARA THERAPEUTICS INC171757957PUT500$0thousands by filing dateputValue filed as zero, left out of ratios.
CSI COMPRESSCO LP12637A903CALL500$0thousands by filing datecallValue filed as zero, left out of ratios.
ALMADEN MINERALS LTD020283955PUT400$0thousands by filing dateputValue filed as zero, left out of ratios.
FLUENT INC34380C952PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
CASA SYS INC14713L902CALL100$0thousands by filing datecallValue filed as zero, left out of ratios.
CASA SYS INC14713L952PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
PERASO INC71360T901CALL400$0thousands by filing datecallValue filed as zero, left out of ratios.
PERASO INC71360T951PUT200$0thousands by filing dateputValue filed as zero, left out of ratios.
JASPER THERAPEUTICS INC471871953PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
BETTER THERAPEUTICS INC08773T904CALL100$0thousands by filing datecallValue filed as zero, left out of ratios.
TITAN PHARMACEUTICALS INC DE888314956PUT500$0thousands by filing dateputValue filed as zero, left out of ratios.
STARTEK INC85569C957PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
NEMAURA MED INC640442958PUT200$0thousands by filing dateputValue filed as zero, left out of ratios.
YATSEN HLDG LTD985194959PUT600$0thousands by filing dateputValue filed as zero, left out of ratios.
EFFECTOR THERAPEUTICS INC28202V908CALL100$0thousands by filing datecallValue filed as zero, left out of ratios.
LIVEVOX HOLDING INC53838L950PUT200$0thousands by filing dateputValue filed as zero, left out of ratios.
Sigma Additive Solutions, Inc.826598500common110$0thousands by filing dateValue filed as zero, left out of ratios.
MEDAVAIL HOLDINGS INC58406B103COM854$0thousands by filing dateValue filed as zero, left out of ratios.
SEELOS THERAPEUTICS INC81577F959COM300$0thousands by filing dateputValue filed as zero, left out of ratios.
SURGALIGN HOLDINGS INC86882C105COM1,470$0thousands by filing dateValue filed as zero, left out of ratios.
AURORA MOBILE LTD051857950PUT200$0thousands by filing dateputValue filed as zero, left out of ratios.
PARATEK PHARMACEUTICALS INC699374952PUT200$0thousands by filing dateputValue filed as zero, left out of ratios.
ORIENTAL CULTURE HOLDING LTDG6796W957PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
CATALYST BIOSCIENCES INC14888D958PUT800$0thousands by filing dateputValue filed as zero, left out of ratios.
FREQUENCY THERAPEUTICS INC35803L958PUT300$0thousands by filing dateputValue filed as zero, left out of ratios.
KUBIENT INC50116V957PUT200$0thousands by filing dateputValue filed as zero, left out of ratios.
A K A BRANDS HLDG CORP00152K951PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
MEDIWOUND LTDM68830104ORD SHS452$0thousands by filing dateValue filed as zero, left out of ratios.
TALIS BIOMEDICAL CORP87424L908CALL500$0thousands by filing datecallValue filed as zero, left out of ratios.
TALIS BIOMEDICAL CORP87424L958PUT700$0thousands by filing dateputValue filed as zero, left out of ratios.
DIVERSEY HLDGS LTDG28923903CALL100$0thousands by filing datecallValue filed as zero, left out of ratios.
DIVERSEY HLDGS LTDG28923953PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
BENITEC BIOPHARMA INC08205P950PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
LIQUID MEDIA GROUP LTD NEW53634Q954PUT1,200$0thousands by filing dateputValue filed as zero, left out of ratios.
ARIDIS PHARMACEUTICALS INC040334904CALL400$0thousands by filing datecallValue filed as zero, left out of ratios.
NOVAN INC66988N905CALL100$0thousands by filing datecallValue filed as zero, left out of ratios.
VACCINEX INC918640953PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
APTINYX INC03836N953PUT200$0thousands by filing dateputValue filed as zero, left out of ratios.
LISTED FD TR53656F342ROUNDHILL MEME11$0thousands by filing dateValue filed as zero, left out of ratios.
LEAP THERAPEUTICS INC52187K951PUT400$0thousands by filing dateputValue filed as zero, left out of ratios.
AGROFRESH SOLUTIONS00856G909CALL100$0thousands by filing datecallValue filed as zero, left out of ratios.
CALYXT INC13173L907CALL500$0thousands by filing datecallValue filed as zero, left out of ratios.
HEPION PHARMACEUTICALS INC426897954PUT400$0thousands by filing dateputValue filed as zero, left out of ratios.
VERASTEM INC92337C954PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
ASPIRA WOMENS HEALTH INC04537Y909CALL100$0thousands by filing datecallValue filed as zero, left out of ratios.
MUSTANG BIO INC62818Q904CALL300$0thousands by filing datecallValue filed as zero, left out of ratios.
SATSUMA PHARMACEUTICALS INC80405P957PUT200$0thousands by filing dateputValue filed as zero, left out of ratios.
ACUITYADS HLDGS INC00510L956PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
EASTSIDE DISTILLING INC277802902CALL400$0thousands by filing datecallValue filed as zero, left out of ratios.
IZEA WORLDWIDE INC46604H955PUT500$0thousands by filing dateputValue filed as zero, left out of ratios.
POLARITYTE INC731094108COM608$0thousands by filing dateValue filed as zero, left out of ratios.
ANPAC BIO MED SCIENCE CO LTD03635R107cs882$0thousands by filing dateValue filed as zero, left out of ratios.
BTRS HOLDINGS INC11778X954PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
REALNETWORKS INC75605L908CALL700$0thousands by filing datecallValue filed as zero, left out of ratios.
ZOVIO INC98979V952PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
SECOO HLDG LTD81367P101ADR1,561$0thousands by filing dateValue filed as zero, left out of ratios.
FORMA THERAPEUTICS HLDGS INC34633R904CALL100$0thousands by filing datecallValue filed as zero, left out of ratios.
NABRIVA THERAPEUTICS PLCG63637113SHS225$0thousands by filing dateValue filed as zero, left out of ratios.
ALTAMIRA THERAPEUTICS LTDG0360L100SHS852$0thousands by filing dateValue filed as zero, left out of ratios.
TEAM INC878155950PUT200$0thousands by filing dateputValue filed as zero, left out of ratios.
GEMINI THERAPEUTICS INC36870G905CALL600$0thousands by filing datecallValue filed as zero, left out of ratios.
GEMINI THERAPEUTICS INC36870G955PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
QUALIGEN THERAPEUTICS INC74754R953PUT300$0thousands by filing dateputValue filed as zero, left out of ratios.
GROM SOCIAL ENTERPRISES INC39878L958PUT300$0thousands by filing dateputValue filed as zero, left out of ratios.
QUOTIENT LTDG73268957PUT200$0thousands by filing dateputValue filed as zero, left out of ratios.
HALL OF FAME RESORT & ENTMT40619L952PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
TUESDAY MORNING CORP89904V901CALL100$0thousands by filing datecallValue filed as zero, left out of ratios.
SWEDISH EXPT CR CORP870297901CALL100$0thousands by filing datecallValue filed as zero, left out of ratios.
APPLIED GENETIC TECHNOL CORP03820J950PUT300$0thousands by filing dateputValue filed as zero, left out of ratios.
IMV INC44974L953PUT400$0thousands by filing dateputValue filed as zero, left out of ratios.
YUMANITY THERAPEUTICS INC98872L902CALL300$0thousands by filing datecallValue filed as zero, left out of ratios.
YUMANITY THERAPEUTICS INC98872L952PUT400$0thousands by filing dateputValue filed as zero, left out of ratios.
ONECONNECT FINL TECHNOLOGY C68248T905CALL500$0thousands by filing datecallValue filed as zero, left out of ratios.
ONECONNECT FINL TECHNOLOGY C68248T955PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
ONCOSEC MED INC68234L906CALL300$0thousands by filing datecallValue filed as zero, left out of ratios.
ONCOSEC MED INC68234L956PUT200$0thousands by filing dateputValue filed as zero, left out of ratios.
SECOO HLDG LTD81367P901CALL400$0thousands by filing datecallValue filed as zero, left out of ratios.
SECOO HLDG LTD81367P951PUT800$0thousands by filing dateputValue filed as zero, left out of ratios.
CREATD INC225265957PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
NEWAGE INC650194953PUT900$0thousands by filing dateputValue filed as zero, left out of ratios.
ENVERIC BIOSCIENCES INC29405E109COM NEW971$0thousands by filing dateValue filed as zero, left out of ratios.
NEUROBO PHARMACEUTICALS INC64132R107COM132$0thousands by filing dateValue filed as zero, left out of ratios.
RISE ED CAYMAN LTD76761L102SPONSORED ADR111$0thousands by filing dateValue filed as zero, left out of ratios.
AVALO THERAPEUTICS INC05338F908COM15,100$0thousands by filing datecallValue filed as zero, left out of ratios.
AVALO THERAPEUTICS INC05338F958COM200$0thousands by filing dateputValue filed as zero, left out of ratios.
ENVERIC BIOSCIENCES INC29405E909COM NEW1,100$0thousands by filing datecallValue filed as zero, left out of ratios.
SHIFTPIXY INC82452L953COM NEW1,200$0thousands by filing dateputValue filed as zero, left out of ratios.
SOLENO THERAPEUTICS INC834203900COM NEW500$0thousands by filing datecallValue filed as zero, left out of ratios.
CATCHMARK TIMBER TR INC14912Y952PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
ABEONA THERAPEUTICS INC00289Y957PUT2,000$0thousands by filing dateputValue filed as zero, left out of ratios.
NEUROBO PHARMACEUTICALS INC64132R907CALL300$0thousands by filing datecallValue filed as zero, left out of ratios.
NEUROBO PHARMACEUTICALS INC64132R957PUT200$0thousands by filing dateputValue filed as zero, left out of ratios.
SOLENO THERAPEUTICS INC834203950PUT200$0thousands by filing dateputValue filed as zero, left out of ratios.
NABRIVA THERAPEUTICS PLCG63637953PUT700$0thousands by filing dateputValue filed as zero, left out of ratios.
IT TECH PACKAGING INC46527C950PUT1,900$0thousands by filing dateputValue filed as zero, left out of ratios.
FIELD TRIP HEALTH LTD31656R952PUT500$0thousands by filing dateputValue filed as zero, left out of ratios.
ENVERIC BIOSCIENCES INC29405E959PUT900$0thousands by filing dateputValue filed as zero, left out of ratios.
SYROS PHARMACEUTICALS INC87184Q957PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
ELECTRIC LAST MILE SOLUTNS I28489L954PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
JUPAI HLDGS LTD48205B907CALL200$0thousands by filing datecallValue filed as zero, left out of ratios.
KALEIDO BIOSCIENCES INC483347900CALL600$0thousands by filing datecallValue filed as zero, left out of ratios.
SURGALIGN HOLDINGS INC86882C955COM1,800$0thousands by filing dateputValue filed as zero, left out of ratios.
SLR SENIOR INVESTMENT CORP83416M905COM600$0thousands by filing datecallValue filed as zero, left out of ratios.
BP MIDSTREAM PARTNERS LP0556EL909UNIT LTD PTNR3,600$0thousands by filing datecallValue filed as zero, left out of ratios.
UTSTARCOM HOLDINGS CORPG9310A904SHS NEW700$0thousands by filing datecallValue filed as zero, left out of ratios.
BEST INC08653C956SPONSORED ADS100$0thousands by filing dateputValue filed as zero, left out of ratios.
SPX FLOW INC78469X957COM2,400$0thousands by filing dateputValue filed as zero, left out of ratios.
INVESTORS BANCORP INC NEW46146L901COM300$0thousands by filing datecallValue filed as zero, left out of ratios.
INVESTORS BANCORP INC NEW46146L951COM100$0thousands by filing dateputValue filed as zero, left out of ratios.
POLARITYTE INC731094908COM100$0thousands by filing datecallValue filed as zero, left out of ratios.
AGILE THERAPEUTICS INC00847L950PUT200$0thousands by filing dateputValue filed as zero, left out of ratios.
POLARITYTE INC731094958PUT700$0thousands by filing dateputValue filed as zero, left out of ratios.
RISE ED CAYMAN LTD76761L952PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
PHOENIX NEW MEDIA LTD71910C953PUT300$0thousands by filing dateputValue filed as zero, left out of ratios.
BOQII HLDG LTD09950L904CALL2,000$0thousands by filing datecallValue filed as zero, left out of ratios.
SOLAR SR CAP LTD83416M955PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
EVOKE PHARMA INC30049G904CALL200$0thousands by filing datecallValue filed as zero, left out of ratios.
ODONATE THERAPEUTICS INC676079956PUT100$0thousands by filing dateputValue filed as zero, left out of ratios.
RESONANT INC76118L902CALL2,100$0thousands by filing datecallValue filed as zero, left out of ratios.
RESONANT INC76118L952PUT48,100$0thousands by filing dateputValue filed as zero, left out of ratios.
FORTERRA INC34960W906CALL500$0thousands by filing datecallValue filed as zero, left out of ratios.
FORTERRA INC34960W956PUT1,100$0thousands by filing dateputValue filed as zero, left out of ratios.

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001488542-22-000006this filing2022-05-02acceptance time not in the bulk data set