13F-HR filed by Ikarian Capital, LLC
Ikarian Capital, LLC filed this 13F-HR for the quarter ended 2024-09-30, filed 2024-11-14, with 145 holding rows worth $717,153,554.
- Accession
- 0001420506-24-002562
- Filer
- CIK 1778253
- Filed
- 2024-11-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q3 2024
A holdings report, 145 entries on the cover page, a total value of $717,153,554 stated on the cover page (in dollars after the unit check, H1), rows summing to $717,153,554 with VALUE read as dollars as filed, 13F file number 028-19721. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| SPDR SER TR | 78464A870 | S&P BIOTECH | 500,000 | $49,400,000 | dollars as filed | put |
| Amgen Inc. | 031162100 | COM | 146,000 | $47,042,660 | dollars as filed | call |
| Vertex Pharmaceuticals Incorporated | 92532F100 | COM | 100,000 | $46,508,000 | dollars as filed | put |
| Vertex Pharmaceuticals Incorporated | 92532F100 | COM | 100,000 | $46,508,000 | dollars as filed | call |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 1,030,277 | $33,885,812 | dollars as filed | |
| CRINETICS PHARMACEUTICALS INC COM | 22663K107 | Stock | 426,913 | $21,815,255 | dollars as filed | |
| JANUX THERAPEUTICS INC | 47103J105 | COM | 365,200 | $16,591,036 | dollars as filed | put |
| BIOHAVEN LTD | G1110E107 | COM | 325,600 | $16,270,232 | dollars as filed | put |
| IMMUNOVANT INC | 45258J102 | COM | 500,000 | $14,255,000 | dollars as filed | call |
| ANAPTYSBIO INC | 032724106 | COM | 404,300 | $13,544,050 | dollars as filed | put |
| ENLIVEN THERAPEUTICS INC COM | 29337E102 | Stock | 499,566 | $12,758,915 | dollars as filed | |
| ANAPTYSBIO INC | 032724106 | COM | 350,000 | $11,725,000 | dollars as filed | call |
| ARCUS BIOSCIENCES INC | 03969F109 | COM | 744,000 | $11,375,760 | dollars as filed | |
| VIRIDIAN THERAPEUTICS INC | 92790C104 | COM | 499,977 | $11,374,478 | dollars as filed | |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 154,835 | $11,302,955 | dollars as filed | |
| SOLENO THERAPEUTICS INC | 834203309 | COM | 221,437 | $11,180,355 | dollars as filed | |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 305,500 | $10,383,945 | dollars as filed | put |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 305,500 | $10,383,945 | dollars as filed | call |
| ULTRAGENYX PHARMACEUTICAL IN | 90400D108 | COM | 179,000 | $9,943,450 | dollars as filed | |
| AVALO THERAPEUTICS INC | 05338F306 | COMMON STOCK | 970,359 | $9,218,411 | dollars as filed | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 170,147 | $8,983,761 | dollars as filed | |
| SPYRE THERAPEUTICS INC | 00773J202 | COM NEW | 302,247 | $8,889,085 | dollars as filed | |
| CATALYST PHARMACEUTICALS INC | 14888U101 | COM | 417,850 | $8,306,858 | dollars as filed | |
| TECTONIC THERAPEUTIC INC | 878972108 | COMMON STOCK | 267,145 | $8,094,495 | dollars as filed | |
| BLUEPRINT MEDICINES CORP | 09627Y109 | COM | 85,000 | $7,862,501 | dollars as filed | |
| BRIDGEBIO PHARMA INC | 10806X102 | COM | 285,613 | $7,271,706 | dollars as filed | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 54,176 | $6,766,041 | dollars as filed | |
| BEONE MEDICINES LTD SPONSORED ADS | 07725L102 | ADR | 29,800 | $6,690,398 | dollars as filed | call |
| CORBUS PHARMACEUTICALS | 21833P301 | COM NEW | 284,715 | $5,873,670 | dollars as filed | |
| NURIX THERAPEUTICS INC | 67080M103 | COMMON STOCK | 260,000 | $5,842,200 | dollars as filed | |
| APELLIS PHARMACEUTICALS INC | 03753U106 | COM | 200,000 | $5,768,000 | dollars as filed | put |
| AKERO THERAPEUTICS INC | 00973Y108 | COM | 198,900 | $5,706,441 | dollars as filed | put |
| SOLENO THERAPEUTICS INC | 834203309 | COM | 110,000 | $5,553,900 | dollars as filed | call |
| NUVALENT INC COM | 670703107 | Stock | 52,238 | $5,343,947 | dollars as filed | |
| NEUMORA THERAPEUTICS INC. | 640979100 | COM | 400,000 | $5,284,000 | dollars as filed | put |
| NEUMORA THERAPEUTICS INC. | 640979100 | COM | 400,000 | $5,284,000 | dollars as filed | call |
| ALTO NEUROSCIENCE INC COM SHS | 02157Q109 | Stock | 450,000 | $5,148,000 | dollars as filed | put |
| STRUCTURE THERAPEUTICS INC COMP | 86366E106 | EQUITY | 115,200 | $5,056,129 | dollars as filed | |
| MADRIGAL PHARMACEUTICALS INC COM | 558868105 | Stock | 23,500 | $4,987,170 | dollars as filed | put |
| ALTO NEUROSCIENCE INC COM SHS | 02157Q109 | Stock | 431,000 | $4,930,640 | dollars as filed | call |
| RELAY THERAPEUTICS INC COM | 75943R102 | Stock | 693,350 | $4,908,918 | dollars as filed | |
| LENZ THERAPEUTICS INC | 52635N103 | COM | 204,513 | $4,855,139 | dollars as filed | |
| CORBUS PHARMACEUTICALS | 21833P301 | COM NEW | 233,100 | $4,808,853 | dollars as filed | put |
| DYNE THERAPEUTICS INC COM | 26818M108 | Stock | 133,000 | $4,777,360 | dollars as filed | put |
| CAPRICOR THERAPEUTICS INC | 14070B309 | COMMON STOCK | 300,000 | $4,563,000 | dollars as filed | |
| CAPRICOR THERAPEUTICS INC | 14070B309 | COMMON STOCK | 300,000 | $4,563,000 | dollars as filed | put |
| CAPRICOR THERAPEUTICS INC | 14070B309 | COMMON STOCK | 300,000 | $4,563,000 | dollars as filed | call |
| VIRIDIAN THERAPEUTICS INC | 92790C104 | COM | 200,000 | $4,550,000 | dollars as filed | call |
| WAVE LIFE SCIENCES LTD SHS | Y95308105 | Stock | 544,265 | $4,462,973 | dollars as filed | |
| APELLIS PHARMACEUTICALS INC | 03753U106 | COM | 150,000 | $4,326,000 | dollars as filed | call |
| REZOLUTE INC | 76200L309 | COMMON STOCK | 887,230 | $4,303,066 | dollars as filed | |
| Amgen Inc. | 031162100 | COM | 13,300 | $4,285,394 | dollars as filed | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 107,187 | $4,219,953 | dollars as filed | |
| EVOLUS INC | 30052C107 | COM | 258,279 | $4,184,120 | dollars as filed | |
| BLACK DIAMOND THERAPEUTICS I | 09203E105 | COM | 950,000 | $4,132,500 | dollars as filed | put |
| ABEONA THERAPEUTICS INC | 00289Y206 | COM NEW | 583,593 | $3,688,308 | dollars as filed | |
| ROCKET PHARMACEUTICALS INC | 77313F106 | COM | 197,096 | $3,640,363 | dollars as filed | |
| PYXIS ONCOLOGY INC COMMON STOCK | 747324101 | Stock | 957,408 | $3,513,688 | dollars as filed | |
| SILENCE THERAPEUTICS PLC | 82686Q101 | ADS | 587,343 | $3,374,286 | dollars as filed | |
| ACELYRIN INC | 00445A100 | COM | 677,074 | $3,337,975 | dollars as filed | |
| CYBIN INC | 23256X407 | COM NEW | 367,195 | $3,264,364 | dollars as filed | |
| BLACK DIAMOND THERAPEUTICS I | 09203E105 | COM | 700,000 | $3,045,000 | dollars as filed | call |
| CERVOMED INC | 15713L109 | COM | 202,345 | $2,954,237 | dollars as filed | |
| Tourmaline Bio Inc | 89157D105 | Common Stock | 108,483 | $2,789,099 | dollars as filed | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 52,300 | $2,761,440 | dollars as filed | call |
| SANA BIOTECHNOLOGY INC | 799566104 | COM | 650,000 | $2,704,000 | dollars as filed | put |
| SANA BIOTECHNOLOGY INC | 799566104 | COM | 650,000 | $2,704,000 | dollars as filed | call |
| TERNS PHARMACEUTICALS INC COM | 880881107 | Stock | 308,497 | $2,572,865 | dollars as filed | |
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 8,741 | $2,404,038 | dollars as filed | |
| LEXEO THERAPEUTICS INC | 52886X107 | COMMON STOCK | 257,216 | $2,325,233 | dollars as filed | |
| CORBUS PHARMACEUTICALS | 21833P301 | COM NEW | 107,800 | $2,223,914 | dollars as filed | call |
| MINERALYS THERAPEUTICS INC | 603170101 | COM | 180,000 | $2,179,800 | dollars as filed | |
| SOLID BIOSCIENCES INC | 83422E204 | COMMON STOCK | 300,000 | $2,091,000 | dollars as filed | call |
| RENEO PHARMACEUTICALS INC | 75974E103 | COM | 1,025,668 | $1,743,635 | dollars as filed | |
| ARCUS BIOSCIENCES INC | 03969F109 | COM | 113,700 | $1,738,473 | dollars as filed | call |
| NEKTAR THERAPEUTICS | 640268108 | COM | 1,312,405 | $1,706,126 | dollars as filed | |
| MONTE ROSA THERAPEUTICS INC | 61225M102 | COM | 311,593 | $1,651,443 | dollars as filed | |
| BEONE MEDICINES LTD SPONSORED ADS | 07725L102 | ADR | 88,167 | $1,641,345 | dollars as filed | |
| SCHOLAR ROCK HLDG CORP | 80706P103 | COM | 202,100 | $1,618,821 | dollars as filed | put |
| SCHOLAR ROCK HLDG CORP | 80706P103 | COM | 202,100 | $1,618,821 | dollars as filed | call |
| FULCRUM THERAPEUTICS INC | 359616109 | COMMON STOCK | 422,800 | $1,509,396 | dollars as filed | call |
| ACHILLES THERAPEUTICS PL-ADR | 00449L102 | COM | 1,443,181 | $1,472,045 | dollars as filed | |
| SPRINGWORKS THERAPEUTICS INC | 85205L107 | COM | 43,800 | $1,403,352 | dollars as filed | call |
| GALECTIN THERAPEUTICS INC | 363225202 | COMMON STOCK | 500,000 | $1,375,000 | dollars as filed | put |
| GALECTIN THERAPEUTICS INC | 363225202 | COMMON STOCK | 500,000 | $1,375,000 | dollars as filed | call |
| IBIO INC | 451033708 | CMN | 600,000 | $1,332,000 | dollars as filed | |
| PYXIS ONCOLOGY INC COMMON STOCK | 747324101 | Stock | 358,600 | $1,316,062 | dollars as filed | call |
| COMPASS PATHWAYS PLC | 20451W101 | SPONSORED ADS | 202,908 | $1,278,320 | dollars as filed | |
| KODIAK SCIENCES INC | 50015M109 | COM | 476,586 | $1,243,890 | dollars as filed | |
| MARINUS PHARMACEUTICALS INC | 56854Q200 | COM NEW | 706,154 | $1,242,831 | dollars as filed | |
| ROIVANT SCIENCES LTD | G76279101 | SHS | 100,609 | $1,161,028 | dollars as filed | |
| CORVUS PHARMACEUTICALS INC | 221015100 | COM | 218,300 | $1,152,624 | dollars as filed | call |
| OLEMA PHARMACEUTICALS INC | 68062P106 | COM | 92,000 | $1,098,479 | dollars as filed | |
| Inflarx Nv | N44821101 | COM | 704,987 | $1,078,630 | dollars as filed | |
| SAGIMET BIOSCIENCES INC A | 786700104 | COMMON STOCK | 387,565 | $1,073,555 | dollars as filed | |
| JASPER THERAPEUTICS INC | 471871202 | COM NEW | 55,175 | $1,037,842 | dollars as filed | |
| PERSPECTIVE THERAPEUTICS INC | 46489V302 | COMMON STOCK | 77,100 | $1,029,285 | dollars as filed | put |
| BIOMX INC | 09090D301 | COM | 893,000 | $910,860 | dollars as filed | |
| DELCATH SYSTEMS INC | 24661P807 | COMMON STOCK | 100,370 | $906,340 | dollars as filed | |
| CLIMB BIO INC | 28658R106 | COMMON STOCK | 175,100 | $891,258 | dollars as filed | |
| AMYLYX PHARMACEUTICALS INC | 03237H101 | COM | 274,551 | $889,546 | dollars as filed | |
| PROQR THERAPEUTICS NV | N71542109 | SHS EURO | 483,583 | $880,121 | dollars as filed | |
| CARTESIAN THERAPEUTICS INC | 816212302 | COMMON STOCK | 52,193 | $841,352 | dollars as filed | |
| KEZAR LIFE SCIENCES INC | 49372L100 | COM | 1,068,992 | $826,544 | dollars as filed | |
| VERVE THERAPEUTICS INC | 92539P101 | COM | 170,000 | $822,800 | dollars as filed | |
| IMMUNIC INC | 4525EP101 | COM | 493,496 | $814,268 | dollars as filed | |
| ITEOS THERAPEUTICS INC | 46565G104 | COM | 78,574 | $802,241 | dollars as filed | |
| AEROVATE THERAPEUTICS INC | 008064107 | COM | 367,965 | $769,046 | dollars as filed | |
| Veru Inc | 92536C103 | Common Stock | 946,382 | $727,767 | dollars as filed | |
| LYELL IMMUNOPHARMA INC | 55083R104 | COM | 526,066 | $725,971 | dollars as filed | |
| Milestone Pharmaceuticals Inc | 59935V107 | COM | 466,019 | $708,349 | dollars as filed | |
| ACUMEN PHARMACEUTICALS INC | 00509G209 | CMN | 266,435 | $660,759 | dollars as filed | |
| INHIBRX BIOSCIENCES INC | 45720N103 | COM | 42,123 | $659,646 | dollars as filed | |
| ALLAKOS INC | 01671P100 | COM | 972,675 | $635,352 | dollars as filed | |
| IMMATICS N.V | N44445109 | SHS | 49,415 | $563,825 | dollars as filed | |
| BIOMEA FUSION INC | 09077A106 | CMN | 53,000 | $535,300 | dollars as filed | put |
| NYXOAH S A | B6S7WD106 | SHS | 50,699 | $484,175 | dollars as filed | |
| NEWAMSTERDAM PHARMA CO NV | N62509109 | COMMON STOCK | 29,100 | $483,060 | dollars as filed | call |
| Ventyx Biosciences Inc | 92332V107 | Common Stock | 192,647 | $419,970 | dollars as filed | |
| ELEVATION ONCOLOGY INC COM | 28623U101 | Stock | 690,089 | $413,984 | dollars as filed | |
| SENSEI BIOTHERAPEUTICS INC | 81728A108 | COM | 650,000 | $388,700 | dollars as filed | |
| LARIMAR THERAPEUTICS INC | 517125100 | COM | 58,528 | $383,358 | dollars as filed | |
| MIND MEDICINE MINDMED INC | 60255C885 | COM NEW | 62,481 | $355,516 | dollars as filed | |
| KARYOPHARM THERAPEUTICS INC | 48576U106 | COM | 409,355 | $339,764 | dollars as filed | |
| CHEMOMAB THERAPEUTICS LTD | 16385C104 | SPONSORED ADS | 213,392 | $335,025 | dollars as filed | |
| VOYAGER THERAPEUTICS INC | 92915B106 | COMMON STOCK | 55,857 | $326,763 | dollars as filed | |
| RAPT THERAPEUTICS INC | 75382E109 | COM | 154,625 | $310,796 | dollars as filed | |
| ANEBULO PHARMACEUTICALS INC | 034569103 | COM | 157,862 | $304,675 | dollars as filed | |
| APOGEE THERAPEUTICS INC COM | 03770N101 | Stock | 5,000 | $293,700 | dollars as filed | call |
| PROTARA THERAPEUTICS INC | 74365U107 | COM STK | 155,712 | $284,953 | dollars as filed | |
| LYRA THERAPEUTICS INC | 55234L105 | COM | 1,056,829 | $271,606 | dollars as filed | |
| AEON BIOPHARMA INC | 00791X100 | CL A | 257,977 | $270,876 | dollars as filed | |
| FULCRUM THERAPEUTICS INC | 359616109 | COMMON STOCK | 75,000 | $267,750 | dollars as filed | |
| MACROGENICS INC | 556099109 | COM | 80,079 | $263,460 | dollars as filed | |
| HOOKIPA PHARMA INC | 43906K209 | COM NEW | 53,076 | $228,227 | dollars as filed | |
| PROTHENA CORP PLC SHS | G72800108 | Stock | 11,800 | $197,414 | dollars as filed | put |
| PROTHENA CORP PLC SHS | G72800108 | Stock | 11,800 | $197,414 | dollars as filed | call |
| NUVATION BIO INC COM CL A | 67080N101 | Stock | 83,282 | $190,716 | dollars as filed | |
| Tempest Therapeutics, Inc. | 87978U108 | Common Stock | 105,600 | $147,840 | dollars as filed | |
| RELMADA THERAPEUTICS INC | 75955J402 | COMMON STOCK | 40,369 | $130,795 | dollars as filed | |
| STOKE THERAPEUTICS INC | 86150R107 | COM | 6,816 | $83,768 | dollars as filed | |
| FULCRUM THERAPEUTICS INC | 359616109 | COMMON STOCK | 22,800 | $81,396 | dollars as filed | put |
| SYNLOGIC INC | 87166L209 | COM | 20,448 | $30,468 | dollars as filed | |
| CYTOMX THERAPEUTICS INC | 23284F105 | COMMON STOCK | 8,924 | $10,529 | dollars as filed | |
| 4D MOLECULAR THERAPEUTICS INC COM | 35104E100 | Stock | 39 | $421 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001420506-24-002562 | this filing | 2024-11-14 | acceptance time not in the bulk data set |