13F-HR/A filed by Ikarian Capital, LLC
Ikarian Capital, LLC filed this 13F-HR/A for the quarter ended 2024-03-31, filed 2024-05-17, with 137 holding rows worth $912,049,481.
- Accession
- 0001420506-24-001013
- Filer
- CIK 1778253
- Filed
- 2024-05-17
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q1 2024
A holdings report, amendment of type restatement, 137 entries on the cover page, a total value of $912,049,481 stated on the cover page (in dollars after the unit check, H1), rows summing to $912,049,481 with VALUE read as dollars as filed, 13F file number 028-19721. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| KRYSTAL BIOTECH INC COM | 501147102 | Stock | 375,000 | $66,723,750 | dollars as filed | put |
| SPDR SER TR | 78464A870 | S&P BIOTECH | 700,000 | $66,423,000 | dollars as filed | put |
| CRINETICS PHARMACEUTICALS INC COM | 22663K107 | Stock | 643,751 | $30,133,984 | dollars as filed | |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 710,277 | $25,818,568 | dollars as filed | |
| CORCEPT THERAPEUTICS INC | 218352102 | COM | 994,500 | $25,051,455 | dollars as filed | put |
| DISC MEDICINE INC COM | 254604101 | Stock | 396,600 | $24,692,316 | dollars as filed | put |
| SOLENO THERAPEUTICS INC | 834203309 | COM | 565,411 | $24,199,591 | dollars as filed | |
| CORBUS PHARMACEUTICALS | 21833P301 | COM NEW | 559,271 | $21,945,794 | dollars as filed | |
| ASTRAZENECA PLC SPONSORED ADR | 046353108 | ADR | 309,200 | $20,948,300 | dollars as filed | call |
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 136,700 | $20,429,815 | dollars as filed | put |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 152,278 | $19,713,910 | dollars as filed | |
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 120,800 | $18,053,560 | dollars as filed | call |
| KRYSTAL BIOTECH INC COM | 501147102 | Stock | 100,000 | $17,793,000 | dollars as filed | call |
| Amgen Inc. | 031162100 | COM | 60,000 | $17,059,200 | dollars as filed | call |
| VIKING THERAPEUTICS INC | 92686J106 | COM | 200,000 | $16,400,000 | dollars as filed | put |
| BIOMEA FUSION INC | 09077A106 | CMN | 1,077,600 | $16,110,120 | dollars as filed | call |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 116,100 | $15,030,306 | dollars as filed | call |
| CRINETICS PHARMACEUTICALS INC COM | 22663K107 | Stock | 300,400 | $14,061,724 | dollars as filed | put |
| MADRIGAL PHARMACEUTICALS INC COM | 558868105 | Stock | 51,400 | $13,725,856 | dollars as filed | put |
| EYEPOINT INC COM NEW | 30233G209 | Stock | 658,200 | $13,604,994 | dollars as filed | put |
| BIOHAVEN LTD | G1110E107 | COM | 223,700 | $12,234,153 | dollars as filed | call |
| BRIDGEBIO PHARMA INC | 10806X102 | COM | 389,400 | $12,040,248 | dollars as filed | call |
| AEROVATE THERAPEUTICS INC | 008064107 | COM | 367,965 | $10,880,725 | dollars as filed | |
| LANTHEUS HLDGS INC | 516544103 | COM | 170,000 | $10,580,800 | dollars as filed | call |
| ACELYRIN INC | 00445A100 | COM | 1,564,340 | $10,559,295 | dollars as filed | |
| ALPINE IMMUNE SCIENCES INC | 02083G100 | COM | 261,365 | $10,360,508 | dollars as filed | |
| PRAXIS PRECISION MEDICINES I | 74006W207 | COM NEW | 168,388 | $10,275,036 | dollars as filed | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 145,147 | $10,176,256 | dollars as filed | |
| ANNEXON INC | 03589W102 | COM | 1,405,000 | $10,073,850 | dollars as filed | |
| ALEXANDRIA REAL ESTATE EQ INC COM | 015271109 | REIT | 73,300 | $9,449,103 | dollars as filed | put |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 347,200 | $9,419,536 | dollars as filed | call |
| IMMUNOVANT INC | 45258J102 | COM | 276,925 | $8,947,446 | dollars as filed | |
| BRIDGEBIO PHARMA INC | 10806X102 | COM | 282,013 | $8,719,842 | dollars as filed | |
| CATALYST PHARMACEUTICALS INC | 14888U101 | COM | 518,386 | $8,263,073 | dollars as filed | |
| 4D MOLECULAR THERAPEUTICS INC COM | 35104E100 | Stock | 257,600 | $8,207,136 | dollars as filed | put |
| 4D MOLECULAR THERAPEUTICS INC COM | 35104E100 | Stock | 257,600 | $8,207,136 | dollars as filed | call |
| ROCKET PHARMACEUTICALS INC | 77313F106 | COM | 297,096 | $8,003,767 | dollars as filed | |
| MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD | 61559X104 | Stock | 158,000 | $7,936,340 | dollars as filed | put |
| MACROGENICS INC | 556099109 | COM | 523,500 | $7,705,920 | dollars as filed | call |
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 51,541 | $7,702,802 | dollars as filed | |
| NUVALENT INC COM | 670703107 | Stock | 101,601 | $7,629,219 | dollars as filed | |
| PYXIS ONCOLOGY INC COMMON STOCK | 747324101 | Stock | 1,662,408 | $7,081,858 | dollars as filed | |
| CORCEPT THERAPEUTICS INC | 218352102 | COM | 279,500 | $7,040,605 | dollars as filed | call |
| CYTOKINETICS INC | 23282W605 | COM NEW | 100,000 | $7,011,000 | dollars as filed | put |
| LYRA THERAPEUTICS INC | 55234L105 | COM | 1,056,829 | $6,573,477 | dollars as filed | |
| ABEONA THERAPEUTICS INC | 00289Y206 | COM NEW | 888,593 | $6,442,299 | dollars as filed | |
| SCHOLAR ROCK HLDG CORP | 80706P103 | COM | 362,300 | $6,434,448 | dollars as filed | call |
| VERONA PHARMA PLC | 925050106 | SPONSORED ADS | 375,310 | $6,038,738 | dollars as filed | |
| APELLIS PHARMACEUTICALS INC | 03753U106 | COM | 100,000 | $5,878,000 | dollars as filed | put |
| ARCUTIS BIOTHERAPEUTICS INC | 03969K108 | COM | 589,642 | $5,843,352 | dollars as filed | |
| CYBIN INC | 23256X100 | COM | 13,953,488 | $5,769,768 | dollars as filed | |
| ASTRIA THERAPEUTICS INC COM | 04635X102 | Stock | 400,000 | $5,630,000 | dollars as filed | call |
| CERVOMED INC | 15713L109 | COM | 237,345 | $5,530,138 | dollars as filed | |
| SCHOLAR ROCK HLDG CORP | 80706P103 | COM | 291,701 | $5,180,610 | dollars as filed | |
| STRUCTURE THERAPEUTICS INC COMP | 86366E106 | EQUITY | 120,400 | $5,160,344 | dollars as filed | put |
| MARINUS PHARMACEUTICALS INC | 56854Q200 | COM NEW | 537,925 | $4,862,842 | dollars as filed | |
| MACROGENICS INC | 556099109 | COM | 318,167 | $4,683,418 | dollars as filed | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 107,187 | $4,614,400 | dollars as filed | |
| NURIX THERAPEUTICS INC | 67080M103 | COMMON STOCK | 300,000 | $4,410,000 | dollars as filed | |
| EYEPOINT INC COM NEW | 30233G209 | Stock | 206,500 | $4,268,355 | dollars as filed | call |
| Tourmaline Bio Inc | 89157D105 | Common Stock | 179,200 | $4,103,680 | dollars as filed | call |
| ALPINE IMMUNE SCIENCES INC | 02083G100 | COM | 103,000 | $4,082,920 | dollars as filed | call |
| WAVE LIFE SCIENCES LTD SHS | Y95308105 | Stock | 590,088 | $3,640,843 | dollars as filed | |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 100,000 | $3,635,000 | dollars as filed | call |
| SOLENO THERAPEUTICS INC | 834203309 | COM | 81,100 | $3,471,080 | dollars as filed | call |
| CABALETTA BIO INC | 12674W109 | COMMON STOCK | 200,000 | $3,412,000 | dollars as filed | put |
| LARIMAR THERAPEUTICS INC | 517125100 | COM | 438,528 | $3,328,427 | dollars as filed | |
| VIRIDIAN THERAPEUTICS INC | 92790C104 | COM | 178,900 | $3,132,539 | dollars as filed | put |
| DISC MEDICINE INC COM | 254604101 | Stock | 49,600 | $3,088,096 | dollars as filed | call |
| JASPER THERAPEUTICS INC | 471871202 | COM NEW | 105,175 | $3,087,939 | dollars as filed | |
| AMYLYX PHARMACEUTICALS INC | 03237H101 | COM | 1,060,100 | $3,010,684 | dollars as filed | call |
| ANNOVIS BIO INC | 03615A108 | COM | 251,900 | $2,997,610 | dollars as filed | put |
| AEON BIOPHARMA INC | 00791X100 | CL A | 257,977 | $2,992,534 | dollars as filed | |
| ANNOVIS BIO INC | 03615A108 | COM | 250,000 | $2,975,000 | dollars as filed | call |
| MIND MEDICINE MINDMED INC | 60255C885 | COM NEW | 297,481 | $2,796,321 | dollars as filed | |
| Ventyx Biosciences Inc | 92332V107 | Common Stock | 507,647 | $2,792,059 | dollars as filed | |
| MARINUS PHARMACEUTICALS INC | 56854Q200 | COM NEW | 303,200 | $2,740,928 | dollars as filed | call |
| KODIAK SCIENCES INC | 50015M109 | COM | 476,586 | $2,506,842 | dollars as filed | |
| Tourmaline Bio Inc | 89157D105 | Common Stock | 108,483 | $2,484,260 | dollars as filed | |
| UNIQURE NV | N90064101 | SHS | 469,133 | $2,439,492 | dollars as filed | |
| IBIO INC | 451033708 | CMN | 600,000 | $2,436,000 | dollars as filed | |
| NUVATION BIO INC COM CL A | 67080N101 | Stock | 633,282 | $2,305,146 | dollars as filed | |
| SAGIMET BIOSCIENCES INC A | 786700104 | COMMON STOCK | 412,565 | $2,236,103 | dollars as filed | |
| RAPT THERAPEUTICS INC | 75382E109 | COM | 246,200 | $2,210,876 | dollars as filed | put |
| ASTRIA THERAPEUTICS INC COM | 04635X102 | Stock | 153,700 | $2,163,329 | dollars as filed | put |
| IMMUNIC INC | 4525EP101 | COM | 1,612,378 | $2,128,339 | dollars as filed | |
| APELLIS PHARMACEUTICALS INC | 03753U106 | COM | 35,092 | $2,062,708 | dollars as filed | |
| ASTRIA THERAPEUTICS INC COM | 04635X102 | Stock | 140,687 | $1,980,170 | dollars as filed | |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 70,900 | $1,923,517 | dollars as filed | put |
| MARINUS PHARMACEUTICALS INC | 56854Q200 | COM NEW | 212,200 | $1,918,288 | dollars as filed | put |
| LENZ THERAPEUTICS INC | 52635N103 | COM | 85,000 | $1,898,050 | dollars as filed | |
| ACHILLES THERAPEUTICS PL-ADR | 00449L102 | COM | 1,443,181 | $1,803,976 | dollars as filed | |
| VOYAGER THERAPEUTICS INC | 92915B106 | COMMON STOCK | 180,857 | $1,683,779 | dollars as filed | |
| DISC MEDICINE INC COM | 254604101 | Stock | 25,372 | $1,579,660 | dollars as filed | |
| BIOMEA FUSION INC | 09077A106 | CMN | 103,000 | $1,539,850 | dollars as filed | put |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 51,335 | $1,392,718 | dollars as filed | |
| RAPT THERAPEUTICS INC | 75382E109 | COM | 154,625 | $1,388,532 | dollars as filed | |
| ITEOS THERAPEUTICS INC | 46565G104 | COM | 101,325 | $1,382,073 | dollars as filed | |
| PRAXIS PRECISION MEDICINES I | 74006W207 | COM NEW | 21,800 | $1,330,236 | dollars as filed | call |
| ALLAKOS INC | 01671P100 | COM | 932,675 | $1,175,171 | dollars as filed | |
| PROQR THERAPEUTICS NV | N71542109 | SHS EURO | 483,583 | $1,097,734 | dollars as filed | |
| Inflarx Nv | N44821101 | COM | 704,987 | $1,085,680 | dollars as filed | |
| ACUMEN PHARMACEUTICALS INC | 00509G209 | CMN | 266,435 | $1,079,063 | dollars as filed | |
| ROIVANT SCIENCES LTD | G76279101 | SHS | 100,609 | $1,060,419 | dollars as filed | |
| AVALO THERAPEUTICS INC | 05338F306 | COMMON STOCK | 46,648 | $1,014,594 | dollars as filed | |
| TECTONIC THERAPEUTIC INC COM | 05455M100 | Stock | 754,061 | $965,198 | dollars as filed | |
| AMYLYX PHARMACEUTICALS INC | 03237H101 | COM | 331,451 | $941,321 | dollars as filed | |
| Milestone Pharmaceuticals Inc | 59935V107 | COM | 466,019 | $834,174 | dollars as filed | |
| PROTARA THERAPEUTICS INC | 74365U107 | COM STK | 202,701 | $812,830 | dollars as filed | |
| KEZAR LIFE SCIENCES INC | 49372L100 | COM | 868,992 | $783,484 | dollars as filed | |
| RAPT THERAPEUTICS INC | 75382E109 | COM | 87,200 | $783,056 | dollars as filed | call |
| ELEVATION ONCOLOGY INC COM | 28623U101 | Stock | 148,089 | $759,697 | dollars as filed | |
| NYXOAH S A | B6S7WD106 | SHS | 50,699 | $683,929 | dollars as filed | |
| Veru Inc | 92536C103 | Common Stock | 946,382 | $662,563 | dollars as filed | |
| KARYOPHARM THERAPEUTICS INC | 48576U106 | COM | 409,355 | $618,126 | dollars as filed | |
| TERNS PHARMACEUTICALS INC COM | 880881107 | Stock | 88,497 | $580,540 | dollars as filed | |
| AMYLYX PHARMACEUTICALS INC | 03237H101 | COM | 186,400 | $529,376 | dollars as filed | put |
| IMMATICS N.V | N44445109 | SHS | 49,415 | $519,351 | dollars as filed | |
| GLYCOMIMETICS INC | 38000Q102 | COM | 172,800 | $518,400 | dollars as filed | put |
| GLYCOMIMETICS INC | 38000Q102 | COM | 172,800 | $518,400 | dollars as filed | call |
| ABEONA THERAPEUTICS INC | 00289Y206 | COM NEW | 67,500 | $489,375 | dollars as filed | call |
| ANEBULO PHARMACEUTICALS INC | 034569103 | COM | 157,862 | $453,064 | dollars as filed | |
| Tempest Therapeutics, Inc. | 87978U108 | Common Stock | 105,600 | $412,895 | dollars as filed | |
| CRINETICS PHARMACEUTICALS INC COM | 22663K107 | Stock | 8,700 | $407,247 | dollars as filed | call |
| Q32 BIO INC | 746964105 | Common Stock | 22,335 | $380,588 | dollars as filed | |
| HOOKIPA PHARMA INC | 43906K100 | COM | 530,776 | $377,913 | dollars as filed | |
| RELMADA THERAPEUTICS INC | 75955J402 | COMMON STOCK | 40,369 | $187,717 | dollars as filed | |
| CHEMOMAB THERAPEUTICS LTD | 16385C104 | SPONSORED ADS | 213,392 | $166,232 | dollars as filed | |
| STOKE THERAPEUTICS INC | 86150R107 | COM | 6,816 | $92,017 | dollars as filed | |
| STRUCTURE THERAPEUTICS INC COMP | 86366E106 | EQUITY | 2,000 | $85,720 | dollars as filed | call |
| BRAINSTORM CELL THERAPEUTICS | 10501E201 | COM | 90,242 | $50,960 | dollars as filed | |
| SYNLOGIC INC | 87166L209 | COM | 20,448 | $36,602 | dollars as filed | |
| EYEPOINT INC COM NEW | 30233G209 | Stock | 1,047 | $21,642 | dollars as filed | |
| FINCH THERAPEUTICS GROUP INC | 31773D200 | COM NEW | 6,892 | $18,126 | dollars as filed | |
| TYRA BIOSCIENCES INC | 90240B106 | COMMON STOCK | 501 | $8,216 | dollars as filed | |
| ASLAN PHARMACEUTICALS LTD | 04522R200 | SPON ADS NEW | 35,420 | $6,273 | dollars as filed | |
| LONGBOARD PHARMACEUTICALS IN | 54300N103 | COM | 236 | $5,098 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001420506-24-001000 | superseded | 2024-05-15 | acceptance time not in the bulk data set | |
| 13F-HR/A 0001420506-24-001013 | this filing | 2024-05-17 | acceptance time not in the bulk data set |