13F-HR filed by Ikarian Capital, LLC
Ikarian Capital, LLC filed this 13F-HR for the quarter ended 2023-12-31, filed 2024-02-14, with 136 holding rows worth $1,067,984,222.
- Accession
- 0001420506-24-000473
- Filer
- CIK 1778253
- Filed
- 2024-02-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2023
A holdings report, 136 entries on the cover page, a total value of $1,067,984,222 stated on the cover page (in dollars after the unit check, H1), rows summing to $1,067,984,222 with VALUE read as dollars as filed, 13F file number 028-19721. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| KRYSTAL BIOTECH INC COM | 501147102 | Stock | 412,000 | $51,112,720 | dollars as filed | put |
| CYTOKINETICS INC | 23282W605 | COM NEW | 603,500 | $50,386,215 | dollars as filed | call |
| SPDR SER TR | 78464A870 | S&P BIOTECH | 550,000 | $49,109,500 | dollars as filed | put |
| Eli Lilly and Company | 532457108 | COM | 70,000 | $40,804,400 | dollars as filed | put |
| CRISPR THERAPEUTICS AG NAMEN AKT | H17182108 | Stock | 649,400 | $40,652,440 | dollars as filed | put |
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 169,700 | $32,482,277 | dollars as filed | call |
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 78,100 | $29,711,583 | dollars as filed | put |
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 78,100 | $29,711,583 | dollars as filed | call |
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 70,000 | $26,538,467 | dollars as filed | |
| CRINETICS PHARMACEUTICALS INC COM | 22663K107 | Stock | 680,370 | $24,207,564 | dollars as filed | |
| SOLENO THERAPEUTICS INC | 834203309 | COM | 590,243 | $23,757,281 | dollars as filed | |
| PROTHENA CORP PLC SHS | G72800108 | Stock | 600,000 | $21,804,000 | dollars as filed | call |
| AbbVie,Inc. | 00287Y109 | COM | 132,500 | $20,533,525 | dollars as filed | call |
| SPDR S&P Homebuilders ETF | 78464A888 | SHS | 200,000 | $19,132,000 | dollars as filed | |
| AMYLYX PHARMACEUTICALS INC | 03237H101 | COM | 1,298,400 | $19,112,448 | dollars as filed | call |
| BRIDGEBIO PHARMA INC | 10806X102 | COM | 473,126 | $19,100,096 | dollars as filed | |
| NUVALENT INC COM | 670703107 | Stock | 258,142 | $18,996,671 | dollars as filed | |
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 98,600 | $18,873,026 | dollars as filed | put |
| KARUNA THERAPEUTICS INC | 48576A100 | COM | 58,600 | $18,547,486 | dollars as filed | call |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 182,600 | $17,608,118 | dollars as filed | call |
| LANTHEUS HLDGS INC | 516544103 | COM | 270,000 | $16,740,000 | dollars as filed | call |
| PROTHENA CORP PLC SHS | G72800108 | Stock | 418,400 | $15,204,656 | dollars as filed | put |
| ACELYRIN INC | 00445A100 | COM | 1,991,005 | $14,852,898 | dollars as filed | |
| IMMUNOGEN INC | 45253H101 | COMMON STOCK | 456,800 | $13,544,120 | dollars as filed | call |
| AMYLYX PHARMACEUTICALS INC | 03237H101 | COM | 877,500 | $12,916,799 | dollars as filed | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 132,640 | $12,790,475 | dollars as filed | |
| IMMUNOVANT INC | 45258J102 | COM | 300,700 | $12,668,491 | dollars as filed | call |
| KRYSTAL BIOTECH INC COM | 501147102 | Stock | 100,000 | $12,406,000 | dollars as filed | call |
| MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD | 61559X104 | Stock | 200,600 | $12,114,234 | dollars as filed | put |
| ANNEXON INC | 03589W102 | COM | 2,650,000 | $12,031,001 | dollars as filed | |
| BIOMEA FUSION INC | 09077A106 | CMN | 777,600 | $11,290,752 | dollars as filed | call |
| DISC MEDICINE INC COM | 254604101 | Stock | 194,982 | $11,262,160 | dollars as filed | |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 518,519 | $10,500,010 | dollars as filed | |
| Amgen Inc. | 031162100 | COM | 35,000 | $10,080,700 | dollars as filed | call |
| IMMUNOVANT INC | 45258J102 | COM | 233,394 | $9,832,889 | dollars as filed | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 101,800 | $9,816,574 | dollars as filed | put |
| ALEXANDRIA REAL ESTATE EQ INC COM | 015271109 | REIT | 73,300 | $9,292,241 | dollars as filed | put |
| ALPINE IMMUNE SCIENCES INC | 02083G100 | COM | 487,248 | $9,286,947 | dollars as filed | |
| EYEPOINT INC COM NEW | 30233G209 | Stock | 391,000 | $9,036,010 | dollars as filed | call |
| APELLIS PHARMACEUTICALS INC | 03753U106 | COM | 150,000 | $8,979,000 | dollars as filed | call |
| CORCEPT THERAPEUTICS INC | 218352102 | COM | 271,300 | $8,811,824 | dollars as filed | put |
| CORCEPT THERAPEUTICS INC | 218352102 | COM | 271,300 | $8,811,824 | dollars as filed | call |
| EYEPOINT INC COM NEW | 30233G209 | Stock | 368,130 | $8,507,483 | dollars as filed | |
| CATALYST PHARMACEUTICALS INC | 14888U101 | COM | 505,862 | $8,503,541 | dollars as filed | |
| MARINUS PHARMACEUTICALS INC | 56854Q200 | COM NEW | 746,069 | $8,109,771 | dollars as filed | |
| DYNE THERAPEUTICS INC COM | 26818M108 | Stock | 607,600 | $8,081,080 | dollars as filed | call |
| NUVALENT INC COM | 670703107 | Stock | 104,400 | $7,682,796 | dollars as filed | call |
| ARCUS BIOSCIENCES INC | 03969F109 | COM | 400,000 | $7,640,000 | dollars as filed | call |
| PROTAGONIST THERAPEUTICS | 74366E102 | COM | 319,000 | $7,314,669 | dollars as filed | |
| BIOMEA FUSION INC | 09077A106 | CMN | 500,000 | $7,260,000 | dollars as filed | put |
| ROCKET PHARMACEUTICALS INC | 77313F106 | COM | 239,726 | $7,184,588 | dollars as filed | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 154,089 | $7,097,340 | dollars as filed | put |
| IMMUNOVANT INC | 45258J102 | COM | 164,700 | $6,938,811 | dollars as filed | put |
| ICOSAVAX INC | 45114M109 | COM | 440,000 | $6,934,400 | dollars as filed | |
| LYRA THERAPEUTICS INC | 55234L105 | COM | 1,254,384 | $6,572,971 | dollars as filed | |
| EYEPOINT INC COM NEW | 30233G209 | Stock | 283,200 | $6,544,752 | dollars as filed | put |
| LONGBOARD PHARMACEUTICALS IN | 54300N103 | COM | 979,462 | $5,906,156 | dollars as filed | |
| JAZZ PHARMACEUTICALS PLC SHS USD | G50871105 | Stock | 41,800 | $5,141,400 | dollars as filed | call |
| CABALETTA BIO INC | 12674W109 | COMMON STOCK | 216,620 | $4,917,275 | dollars as filed | |
| FUSION PHARMACEUTICALS INC | 36118A100 | COM | 500,000 | $4,805,001 | dollars as filed | |
| CABALETTA BIO INC | 12674W109 | COMMON STOCK | 200,000 | $4,540,000 | dollars as filed | put |
| ROCKET PHARMACEUTICALS INC | 77313F106 | COM | 150,000 | $4,495,500 | dollars as filed | call |
| PRAXIS PRECISION MEDICINES I | 74006W207 | COM NEW | 200,000 | $4,456,000 | dollars as filed | |
| CRISPR THERAPEUTICS AG NAMEN AKT | H17182108 | Stock | 70,546 | $4,416,180 | dollars as filed | |
| MODERNA INC | 60770K107 | COM | 44,300 | $4,405,635 | dollars as filed | put |
| NOVAVAX INC | 670002401 | COM NEW | 913,200 | $4,383,360 | dollars as filed | put |
| MORPHOSYS AG | 617760202 | ADR | 400,000 | $3,960,000 | dollars as filed | call |
| DYNE THERAPEUTICS INC COM | 26818M108 | Stock | 285,900 | $3,802,470 | dollars as filed | |
| ITEOS THERAPEUTICS INC | 46565G104 | COM | 346,471 | $3,793,857 | dollars as filed | |
| NUVALENT INC COM | 670703107 | Stock | 48,400 | $3,561,756 | dollars as filed | put |
| CRINETICS PHARMACEUTICALS INC COM | 22663K107 | Stock | 100,000 | $3,558,000 | dollars as filed | call |
| NOVAVAX INC | 670002401 | COM NEW | 713,200 | $3,423,360 | dollars as filed | call |
| DYNE THERAPEUTICS INC COM | 26818M108 | Stock | 250,000 | $3,325,000 | dollars as filed | put |
| ABEONA THERAPEUTICS INC | 00289Y206 | COM NEW | 600,000 | $3,006,000 | dollars as filed | |
| EDGEWISE THERAPEUTICS INC | 28036F105 | COM | 270,000 | $2,953,800 | dollars as filed | |
| ASTRIA THERAPEUTICS INC COM | 04635X102 | Stock | 374,807 | $2,878,517 | dollars as filed | |
| LARIMAR THERAPEUTICS INC | 517125100 | COM | 602,868 | $2,743,050 | dollars as filed | |
| IMMUNOGEN INC | 45253H101 | COMMON STOCK | 90,162 | $2,673,303 | dollars as filed | |
| VOYAGER THERAPEUTICS INC | 92915B106 | COMMON STOCK | 305,857 | $2,581,433 | dollars as filed | |
| ACELYRIN INC | 00445A100 | COM | 336,900 | $2,513,274 | dollars as filed | call |
| CYTOKINETICS INC | 23282W605 | COM NEW | 30,000 | $2,504,699 | dollars as filed | |
| MODERNA INC | 60770K107 | COM | 24,546 | $2,441,100 | dollars as filed | |
| MIND MEDICINE MINDMED INC | 60255C885 | COM NEW | 600,000 | $2,195,999 | dollars as filed | |
| APELLIS PHARMACEUTICALS INC | 03753U106 | COM | 34,361 | $2,056,849 | dollars as filed | |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 100,000 | $2,025,000 | dollars as filed | call |
| AEON BIOPHARMA INC | 00791X100 | CL A | 257,977 | $1,857,434 | dollars as filed | |
| NUVATION BIO INC COM CL A | 67080N101 | Stock | 1,222,852 | $1,846,506 | dollars as filed | |
| RENEO PHARMACEUTICALS INC | 75974E103 | COM | 1,082,600 | $1,732,160 | dollars as filed | call |
| ROIVANT SCIENCES LTD | G76279101 | SHS | 151,821 | $1,704,950 | dollars as filed | |
| AUTOLUS THERAPEUTICS PLC SPON | 05280R100 | COM | 262,694 | $1,691,750 | dollars as filed | |
| BLACK DIAMOND THERAPEUTICS I | 09203E105 | COM | 555,572 | $1,561,157 | dollars as filed | |
| RAPT THERAPEUTICS INC | 75382E109 | COM | 58,800 | $1,461,180 | dollars as filed | put |
| KODIAK SCIENCES INC | 50015M109 | COM | 412,881 | $1,255,158 | dollars as filed | |
| ACUMEN PHARMACEUTICALS INC | 00509G209 | CMN | 315,265 | $1,210,617 | dollars as filed | |
| CORBUS PHARMACEUTICALS | 21833P301 | COM NEW | 195,899 | $1,183,230 | dollars as filed | |
| COHERUS ONCOLOGY INC | 19249H103 | COM | 340,787 | $1,134,821 | dollars as filed | |
| Inflarx Nv | N44821101 | COM | 688,604 | $1,122,425 | dollars as filed | |
| TERNS PHARMACEUTICALS INC COM | 880881107 | Stock | 165,480 | $1,073,966 | dollars as filed | |
| UNIQURE NV | N90064101 | SHS | 157,365 | $1,065,361 | dollars as filed | |
| ESPERION THERAPEUTICS INC NEW COM | 29664W105 | Stock | 337,636 | $1,009,532 | dollars as filed | |
| TECTONIC THERAPEUTIC INC COM | 05455M100 | Stock | 718,259 | $976,833 | dollars as filed | |
| PROQR THERAPEUTICS NV | N71542109 | SHS EURO | 472,625 | $935,797 | dollars as filed | |
| LANTHEUS HLDGS INC | 516544103 | COM | 15,000 | $930,000 | dollars as filed | |
| SOLENO THERAPEUTICS INC | 834203309 | COM | 21,200 | $853,300 | dollars as filed | call |
| KEZAR LIFE SCIENCES INC | 49372L100 | COM | 853,391 | $808,503 | dollars as filed | |
| Milestone Pharmaceuticals Inc | 59935V107 | COM | 462,828 | $772,922 | dollars as filed | |
| RENEO PHARMACEUTICALS INC | 75974E103 | COM | 432,600 | $692,160 | dollars as filed | put |
| IMMUNIC INC | 4525EP101 | COM | 450,000 | $675,001 | dollars as filed | call |
| RENEO PHARMACEUTICALS INC | 75974E103 | COM | 421,300 | $674,080 | dollars as filed | |
| TYRA BIOSCIENCES INC | 90240B106 | COMMON STOCK | 48,170 | $667,155 | dollars as filed | |
| ALLAKOS INC | 01671P100 | COM | 237,056 | $647,163 | dollars as filed | |
| ELEVATION ONCOLOGY INC COM | 28623U101 | Stock | 1,171,939 | $629,331 | dollars as filed | |
| STRUCTURE THERAPEUTICS INC COMP | 86366E106 | EQUITY | 14,524 | $591,998 | dollars as filed | |
| VERVE THERAPEUTICS INC | 92539P101 | COM | 41,300 | $575,722 | dollars as filed | put |
| IMMATICS N.V | N44445109 | SHS | 49,031 | $516,296 | dollars as filed | |
| TRACON PHARMACEUTICALS INC | 89237H209 | COM NEW | 2,765,530 | $484,244 | dollars as filed | |
| Tempest Therapeutics, Inc. | 87978U108 | Common Stock | 105,600 | $464,640 | dollars as filed | |
| HOOKIPA PHARMA INC | 43906K100 | COM | 530,776 | $429,929 | dollars as filed | |
| ANEBULO PHARMACEUTICALS INC | 034569103 | COM | 157,862 | $382,026 | dollars as filed | |
| PROTARA THERAPEUTICS INC | 74365U107 | COM STK | 188,664 | $352,802 | dollars as filed | |
| KARYOPHARM THERAPEUTICS INC | 48576U106 | COM | 400,000 | $346,000 | dollars as filed | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 3,500 | $292,215 | dollars as filed | put |
| VERONA PHARMA PLC | 925050106 | SPONSORED ADS | 367,468 | $257,302 | dollars as filed | |
| CRISPR THERAPEUTICS AG NAMEN AKT | H17182108 | Stock | 3,900 | $244,140 | dollars as filed | call |
| RELMADA THERAPEUTICS INC | 75955J402 | COMMON STOCK | 40,369 | $167,128 | dollars as filed | |
| CHEMOMAB THERAPEUTICS LTD | 16385C104 | SPONSORED ADS | 213,392 | $108,829 | dollars as filed | |
| SYNLOGIC INC | 87166L209 | COM | 20,448 | $78,726 | dollars as filed | |
| STOKE THERAPEUTICS INC | 86150R107 | COM | 12,116 | $63,731 | dollars as filed | |
| ANNOVIS BIO INC | 03615A108 | COM | 3,400 | $63,580 | dollars as filed | put |
| FINCH THERAPEUTICS GROUP INC | 31773D200 | COM NEW | 6,892 | $24,881 | dollars as filed | |
| BRAINSTORM CELL THERAPEUTICS | 10501E201 | COM | 90,242 | $24,636 | dollars as filed | |
| ACLARIS THERAPEUTICS INC COM | 00461U105 | Stock | 19,482 | $20,456 | dollars as filed | |
| Ventyx Biosciences Inc | 92332V107 | Common Stock | 5,914 | $14,607 | dollars as filed | |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 200 | $7,932 | dollars as filed | put |
| ASLAN PHARMACEUTICALS LTD | 04522R200 | SPON ADS NEW | 35,420 | $6,531 | dollars as filed | |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 200 | $6,198 | dollars as filed | call |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001420506-24-000473 | this filing | 2024-02-14 | acceptance time not in the bulk data set |