13F-HR/A filed by Frazier Life Sciences Management, L.P.
Frazier Life Sciences Management, L.P. filed this 13F-HR/A for the quarter ended 2022-12-31, filed 2023-02-07, with 44 holding rows worth $1,608,432,541.
- Accession
- 0001420506-23-000277
- Filer
- CIK 1892134
- Filed
- 2023-02-07
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2022
A holdings report, amendment of type restatement, 44 entries on the cover page, a total value of $1,608,432,541 stated on the cover page (in dollars after the unit check, H1), rows summing to $1,608,432,541 with VALUE read as dollars as filed, 13F file number 028-22504. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| HILLEVAX INC | 43157M102 | COM | 9,758,359 | $163,257,346 | dollars as filed | |
| IMAGO BIOSCIENCES INC | 45250K107 | COM | 3,987,207 | $143,340,092 | dollars as filed | |
| ARCUTIS BIOTHERAPEUTICS INC | 03969K108 | COM | 8,684,232 | $128,526,634 | dollars as filed | |
| CHINOOK THERAPEUTICS INC | 16961L106 | COM | 4,345,559 | $113,853,646 | dollars as filed | |
| NEWAMSTERDAM PHARMA CO NV | N62509109 | COMMON STOCK | 9,341,551 | $101,822,906 | dollars as filed | |
| SYNDAX PHARMACEUTICALS INC | 87164F105 | COM | 3,708,838 | $94,389,927 | dollars as filed | |
| PHATHOM PHARMACEUTICALS INC | 71722W107 | COMMON STOCK | 8,407,152 | $94,328,245 | dollars as filed | |
| KRYSTAL BIOTECH INC COM | 501147102 | Stock | 999,737 | $79,199,165 | dollars as filed | |
| MIRUM PHARMACEUTICALS INC | 604749101 | COM | 3,860,107 | $75,272,087 | dollars as filed | |
| VERONA PHARMA PLC | 925050106 | SPONSORED ADS | 2,815,720 | $73,574,764 | dollars as filed | |
| VAXCYTE INC COM | 92243G108 | Stock | 1,397,405 | $67,005,570 | dollars as filed | |
| RHYTHM PHARMACEUTICALS INC | 76243J105 | COM | 1,894,000 | $55,153,280 | dollars as filed | |
| ALLAKOS INC | 01671P100 | COM | 4,792,000 | $40,348,640 | dollars as filed | |
| ANAPTYSBIO INC | 032724106 | COM | 899,700 | $27,881,703 | dollars as filed | |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 1,787,527 | $26,205,146 | dollars as filed | |
| CRINETICS PHARMACEUTICALS INC COM | 22663K107 | Stock | 1,414,823 | $25,891,261 | dollars as filed | |
| REPLIMUNE GROUP INC | 76029N106 | COMMON STOCK | 931,560 | $25,338,432 | dollars as filed | |
| COGENT BIOSCIENCES INC | 19240Q201 | COM | 2,109,154 | $24,381,820 | dollars as filed | |
| ALPINE IMMUNE SCIENCES INC | 02083G100 | COM | 2,985,757 | $21,945,314 | dollars as filed | |
| KALVISTA PHARMACEUTICALS INC | 483497103 | COM | 3,238,859 | $21,894,687 | dollars as filed | |
| GRITSTONE BIO INC | 39868T105 | COM | 5,162,348 | $17,810,101 | dollars as filed | |
| SUTRO BIOPHARMA INC | 869367102 | COM | 1,776,479 | $14,353,950 | dollars as filed | |
| ACADIA PHARMACEUTICALS INC | 004225108 | COM | 857,338 | $13,648,821 | dollars as filed | |
| SILENCE THERAPEUTICS PLC | 82686Q101 | ADS | 881,173 | $13,437,888 | dollars as filed | |
| TREVI THERAPEUTICS INC COM | 89532M101 | Stock | 6,663,590 | $12,860,729 | dollars as filed | |
| CEREVEL THERAPEUTICS HLDNG I | 15678U128 | COM | 393,000 | $12,395,220 | dollars as filed | |
| MERUS N V | N5749R100 | COM | 746,479 | $11,548,030 | dollars as filed | |
| VECTIVBIO HLDG AG | H9060V101 | COM | 1,333,400 | $11,480,574 | dollars as filed | |
| AVIDITY BIOSCIENCES INC COM | 05370A108 | Stock | 500,000 | $11,095,000 | dollars as filed | |
| IMMUNOVANT INC | 45258J102 | COM | 585,759 | $10,397,222 | dollars as filed | |
| TYRA BIOSCIENCES INC | 90240B106 | COMMON STOCK | 1,327,665 | $10,090,254 | dollars as filed | |
| BLUEBIRD BIO INC | 09609G100 | COM | 1,440,757 | $9,970,038 | dollars as filed | |
| ARVINAS INC | 04335A105 | COM | 285,331 | $9,761,174 | dollars as filed | |
| PROTHENA CORP PLC SHS | G72800108 | Stock | 127,900 | $7,705,975 | dollars as filed | |
| AUTOLUS THERAPEUTICS PLC SPON | 05280R100 | COM | 3,746,857 | $7,119,028 | dollars as filed | |
| INTELLIA THERAPEUTICS INC | 45826J105 | COM | 203,684 | $7,106,535 | dollars as filed | |
| THESEUS PHARMACEUTICALS INC | 88369M101 | COM | 1,398,194 | $6,963,006 | dollars as filed | |
| PASSAGE BIO INC | 702712100 | COM | 3,756,915 | $5,184,543 | dollars as filed | |
| ZYMEWORKS INC | 98985Y108 | COM | 610,000 | $4,794,600 | dollars as filed | |
| ACLARIS THERAPEUTICS INC COM | 00461U105 | Stock | 290,189 | $4,570,477 | dollars as filed | |
| ESSA PHARMA INC | 29668H708 | COM NEW | 605,141 | $1,524,955 | dollars as filed | |
| APTINYX INC | 03836N103 | COM | 1,883,244 | $537,290 | dollars as filed | |
| NEWAMSTERDAM PHARMA CO NV-27 | N62509117 | WTS | 500,333 | $434,289 | dollars as filed | |
| NABRIVA THERAPEUTICS PLC SHS NEW 2022 | G63637139 | Common Stock | 17,025 | $32,177 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001420506-23-000230 | superseded | 2023-02-03 | acceptance time not in the bulk data set | |
| 13F-HR/A 0001420506-23-000277 | this filing | 2023-02-07 | acceptance time not in the bulk data set |