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13F-HR/A filed by Ikarian Capital, LLC

Ikarian Capital, LLC filed this 13F-HR/A for the quarter ended 2021-06-30, filed 2021-08-18, with 210 holding rows worth $1,237,007,000.

Accession
0001420506-21-001327
Filed
2021-08-18
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q2 2021

A holdings report, amendment of type restatement, 211 entries on the cover page, a total value of $1,237,007,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $1,237,007,000 with VALUE read as thousands by filing date, 13F file number 028-19721. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
BIOGEN INC COM09062X103Stock270,000$93,491,000thousands by filing datecall
ALNYLAM PHARMACEUTICALS INC COM02043Q107Stock300,000$50,856,000thousands by filing dateput
INTELLIA THERAPEUTICS INC45826J105COM294,400$47,667,000thousands by filing datecall
BIOGEN INC COM09062X103Stock125,962$43,618,000thousands by filing date
ALNYLAM PHARMACEUTICALS INC COM02043Q107Stock195,700$33,176,000thousands by filing datecall
CRISPR THERAPEUTICS AG NAMEN AKTH17182108Stock200,000$32,379,000thousands by filing dateput
FILANA THERAPEUTICS INC14817C107CMN365,000$31,187,000thousands by filing datecall
REATA PHARMACEUTICALS INC75615P103CL A174,900$24,755,000thousands by filing dateput
HORIZON THERAPEUTICS PLCG46188101SHS250,000$23,409,000thousands by filing datecall
CELLDEX THERAPEUTICS INC NEW15117B202COM NEW600,000$20,065,000thousands by filing datecall
CRISPR THERAPEUTICS AG NAMEN AKTH17182108Stock119,711$19,380,000thousands by filing date
APELLIS PHARMACEUTICALS INC03753U106COM300,000$18,960,000thousands by filing dateput
APELLIS PHARMACEUTICALS INC03753U106COM300,000$18,960,000thousands by filing datecall
X4 Pharmaceuticals, Inc.98420X103COM2,719,290$17,676,000thousands by filing date
TRACON PHARMACEUTICALS INC89237H209COM NEW2,716,840$17,631,000thousands by filing date
INCYTE CORP COM45337C102Stock200,000$16,825,000thousands by filing datecall
BAUSCH HEALTH COS INC COM071734107Stock550,000$16,126,000thousands by filing datecall
ZOGENIX INC.98978L204Common Stock850,000$14,688,000thousands by filing datecall
SAGE THERAPEUTICS INC78667J108COM254,300$14,445,000thousands by filing datecall
SAGE THERAPEUTICS INC78667J108COM250,000$14,202,000thousands by filing dateput
ALECTOR INC014442107COMMON STOCK674,723$14,054,000thousands by filing date
LAKEFRONT BIOTHERAPEUTICS NV36315X101SPON ADR200,000$13,867,000thousands by filing date
CHEMOCENTRYX INC16383L106COM967,600$12,956,000thousands by filing dateput
CHIMERIX INC COM16934W106Stock1,575,916$12,608,000thousands by filing date
MACROGENICS INC556099109COM459,602$12,345,000thousands by filing date
CELLDEX THERAPEUTICS INC NEW15117B202COM NEW365,544$12,224,000thousands by filing date
XENON PHARMACEUTICALS INC COM98420N105Stock640,606$11,927,000thousands by filing date
SERES THERAPEUTICS INC81750R102COM500,000$11,924,000thousands by filing datecall
RAPT THERAPEUTICS INC75382E109COM350,000$11,126,000thousands by filing dateput
ARK ETF TR00214Q302GENOMIC REV ETF119,900$11,091,000thousands by filing dateput
Milestone Pharmaceuticals Inc59935V107COM1,980,400$10,893,000thousands by filing date
SIERRA ONCOLOGY INC82640U404CMN545,002$10,628,000thousands by filing date
ARENA PHARMACEUTICALS INC040047607COM NEW150,000$10,230,000thousands by filing datecall
VAXCYTE INC COM92243G108Stock448,110$10,087,000thousands by filing date
OCULAR THERAPEUTIX INC67576A100COM700,000$9,928,000thousands by filing datecall
RELMADA THERAPEUTICS INC75955J402COMMON STOCK300,207$9,609,000thousands by filing date
INTRA-CELLULAR THERAPIES INC46116X101COMMON STOCK230,889$9,425,000thousands by filing date
AUTOLUS THERAPEUTICS PLC SPON05280R100COM1,356,048$9,004,000thousands by filing date
ANNOVIS BIO INC03615A108COM103,527$8,860,000thousands by filing date
FATE THERAPEUTICS INC31189P102COM100,000$8,680,000thousands by filing dateput
INTRA-CELLULAR THERAPIES INC46116X101COMMON STOCK210,000$8,572,000thousands by filing datecall
GOSSAMER BIO INC COM38341P102Stock1,048,383$8,513,000thousands by filing date
CABALETTA BIO INC12674W109COMMON STOCK947,128$8,145,000thousands by filing date
MACROGENICS INC556099109COM300,000$8,056,000thousands by filing datecall
CULLINAN THERAPEUTICS INC230031106COM295,596$7,613,000thousands by filing date
BAUSCH HEALTH COS INC COM071734107Stock250,000$7,329,000thousands by filing dateput
ADC THERAPEUTICS SAH0036K147COMMON STOCK300,000$7,305,000thousands by filing datecall
ALLAKOS INC01671P100COM81,500$6,957,000thousands by filing datecall
ODONATE THERAPEUTICS INC676079106COM1,986,412$6,933,000thousands by filing date
LAKEFRONT BIOTHERAPEUTICS NV36315X101SPON ADR100,000$6,890,000thousands by filing datecall
ARCUS BIOSCIENCES INC03969F109COM245,500$6,742,000thousands by filing dateput
KODIAK SCIENCES INC50015M109COM72,300$6,724,000thousands by filing datecall
SCPHARMACEUTICALS INC810648105COM1,095,024$6,690,000thousands by filing date
FIBROGEN INC31572Q808COM250,000$6,657,000thousands by filing datecall
CLOVIS ONCOLOGY INC189464100COM1,129,473$6,551,000thousands by filing date
RELMADA THERAPEUTICS INC75955J402COMMON STOCK203,400$6,511,000thousands by filing datecall
CHEMOCENTRYX INC16383L106COM471,376$6,312,000thousands by filing date
OCULAR THERAPEUTIX INC67576A100COM419,573$5,951,000thousands by filing date
PROTARA THERAPEUTICS INC74365U107COM STK584,804$5,696,000thousands by filing date
VERASTEM INC92337C104COM1,394,394$5,675,000thousands by filing date
VINCERX PHARMA INC92731L106COM NEW426,743$5,543,000thousands by filing date
CHEMOMAB THERAPEUTICS LTD16385C104SPONSORED ADS290,534$5,526,000thousands by filing date
SHATTUCK LABS INC82024L103COMMON STOCK190,330$5,518,000thousands by filing date
Gilead Sciences,Inc.375558103COM80,000$5,509,000thousands by filing datecall
IOVANCE BIOTHERAPEUTICS INC462260100COM200,000$5,204,000thousands by filing dateput
FIBROGEN INC31572Q808COM193,800$5,161,000thousands by filing dateput
HORIZON THERAPEUTICS PLCG46188101SHS54,815$5,133,000thousands by filing date
ACADIA PHARMACEUTICALS INC004225108COM209,866$5,119,000thousands by filing date
LYRA THERAPEUTICS INC55234L105COM624,684$5,017,000thousands by filing date
U.S. GLOBAL JETS ETF26922A842ETF200,000$4,836,000thousands by filing datecall
FINCH THERAPEUTICS GROUP INC31773D101COM325,000$4,573,000thousands by filing date
IOVANCE BIOTHERAPEUTICS INC462260100COM175,000$4,553,000thousands by filing date
SATSUMA PHARMACEUTICALS INC80405P107COM644,056$4,540,000thousands by filing date
OVID THERAPEUTICS INC690469101COMMON STOCK1,124,872$4,398,000thousands by filing date
CHARDAN HEALTHCR ACQSTN 2 CO15957T206UNIT 99/99/9999400,000$4,369,000thousands by filing date
IMMUNOVANT INC45258J102COM400,000$4,229,000thousands by filing datecall
NEXTCURE INC65343E108COM516,870$4,151,000thousands by filing date
SAREPTA THERAPEUTICS INC803607100COM50,000$3,887,000thousands by filing datecall
TG THERAPEUTICS INC COM88322Q108Stock100,000$3,878,000thousands by filing dateput
NOVABRIDGE BIOSCIENCES44975P103CMN46,066$3,867,000thousands by filing date
ARK ETF TR00214Q302GENOMIC REV ETF40,961$3,789,000thousands by filing date
RADNET INC750491102COM110,647$3,728,000thousands by filing date
KADMON HLDGS INC48283N106COM936,615$3,625,000thousands by filing date
DBV TECHNOLOGIES S A23306J101ADR322,730$3,552,000thousands by filing date
AILERON THERAPEUTICS INC COM NEW00887A105Stock2,800,000$3,500,000thousands by filing date
PHATHOM PHARMACEUTICALS INC71722W107COMMON STOCK100,000$3,386,000thousands by filing date
TRICIDA INC89610F101COM775,294$3,349,000thousands by filing date
XENON PHARMACEUTICALS INC COM98420N105Stock179,100$3,335,000thousands by filing datecall
SYNLOGIC INC87166L100COM848,354$3,301,000thousands by filing date
AMICUS THERAPEUTICS INC03152W109COM341,500$3,292,000thousands by filing date
COMPASS PATHWAYS PLC20451W101SPONSORED ADS85,063$3,245,000thousands by filing date
ALLAKOS INC01671P100COM37,700$3,218,000thousands by filing dateput
PLIANT THERAPEUTICS INC729139105COM108,700$3,165,000thousands by filing date
VIKING THERAPEUTICS INC92686J106COM524,754$3,144,000thousands by filing date
BELLUS HEALTH INC NEW07987C204COM1,010,545$3,142,000thousands by filing date
INCYTE CORP COM45337C102Stock36,533$3,073,000thousands by filing date
BIOATLA INC09077B104COM70,160$2,974,000thousands by filing date
CHEMOCENTRYX INC16383L106COM221,200$2,961,000thousands by filing datecall
SYNAPTOGENIX INC87167T201COM NEW300,000$2,955,000thousands by filing date
CERECOR INC15671L109COM897,330$2,934,000thousands by filing date
VISTAGEN THERAPEUTICS INC92840H202COM916,552$2,887,000thousands by filing date
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR21,825$2,871,000thousands by filing date
AERPIO PHARMACEUTICALS INC00810B105COM1,676,093$2,832,000thousands by filing date
CM LIFE SCIENCES INC18978W109COM CL A200,000$2,803,000thousands by filing date
ELEDON PHARMACEUTICALS INC28617k101COM350,000$2,769,000thousands by filing date
GEMINI THERAPEUTICS INC36870G105CMN426,455$2,759,000thousands by filing date
ALLAKOS INC01671P100COM31,700$2,707,000thousands by filing date
ALPINE IMMUNE SCIENCES INC02083G100COM300,454$2,704,000thousands by filing date
HEPION PHARMACEUTICALS INC426897104COM1,365,059$2,703,000thousands by filing date
SAVARA INC805111101COM1,586,737$2,697,000thousands by filing date
IMMATICS N.VN44445109SHS225,138$2,613,000thousands by filing date
ALLOGENE THERAPEUTICS INC019770106COM100,000$2,609,000thousands by filing datecall
CEL-SCI CORP150837607COM PAR NEW300,000$2,603,000thousands by filing datecall
INMUNE BIO INC45782T105COM146,883$2,580,000thousands by filing date
YUMANITY THERAPEUTICS INC98872L102COM219,470$2,558,000thousands by filing date
LIQUIDIA CORPORATION COM NEW53635D202Stock890,435$2,546,000thousands by filing date
CATALYST BIOSCIENCES INC14888D208COM581,200$2,518,000thousands by filing date
SUTRO BIOPHARMA INC869367102COM135,360$2,515,000thousands by filing date
SOLID BIOSCIENCES INC COM NEW83422E105Stock675,675$2,473,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW120,895$2,393,000thousands by filing date
KALVISTA PHARMACEUTICALS INC483497103COM96,965$2,323,000thousands by filing date
MADRIGAL PHARMACEUTICALS INC COM558868105Stock23,654$2,303,000thousands by filing date
ICAD INC44934S206COM NEW128,137$2,219,000thousands by filing date
ZOGENIX INC.98978L204Common Stock124,091$2,144,000thousands by filing date
ATRECA INC04965G109COM250,000$2,130,000thousands by filing date
HEALTH SCIENCES ACQ CORP 2G4411D109ORD SHS200,000$2,040,000thousands by filing date
CYCLERION THERAPEUTICS INC23255M105COM509,924$1,990,000thousands by filing date
Inflarx NvN44821101COM666,596$1,980,000thousands by filing date
CASI PHARMACEUTICALS INC14757U109COM1,268,154$1,966,000thousands by filing date
QUANTUM SI INC74765K105COM CL A160,000$1,962,000thousands by filing date
IMMUNOVANT INC45258J102COM185,500$1,961,000thousands by filing date
TRILLIUM THERAPEUTICS INC COM NEW89620X506Stock200,000$1,940,000thousands by filing datecall
PASSAGE BIO INC702712100COM145,858$1,932,000thousands by filing date
VASCULAR BIOGENICS LTDM96883109COM800,811$1,915,000thousands by filing date
BLACK DIAMOND THERAPEUTICS I09203E105COM153,941$1,876,000thousands by filing date
EYEPOINT INC COM NEW30233G209Stock208,500$1,875,000thousands by filing datecall
DIAMEDICA THERAPEUTICS INC25253X207COMMON STOCK415,000$1,847,000thousands by filing date
CORBUS PHARMACEUTICALS HLDGS21833P103COM964,100$1,764,000thousands by filing date
MUSTANG BIO INC62818Q104COM526,003$1,747,000thousands by filing date
FULCRUM THERAPEUTICS INC359616109COMMON STOCK162,700$1,705,000thousands by filing date
BELLICUM PHARMACEUTICALS INC COM NEW079481404Stock500,000$1,650,000thousands by filing date
APPLIED GENETIC TECHNOL CORP03820J100COM415,884$1,625,000thousands by filing date
ABCELLERA BIOLOGICS INC COM00288U106Stock73,700$1,621,000thousands by filing datecall
ACLARIS THERAPEUTICS INC COM00461U105Stock89,788$1,577,000thousands by filing date
HARPOON THERAPEUTICS INC41358P106COM113,600$1,576,000thousands by filing date
AC IMMUNE SAH00263105SHS196,208$1,556,000thousands by filing date
ATYR PHARMA INC002120202COM NEW300,000$1,465,000thousands by filing date
AURIS MEDICAL HOLDING LTDG07025201SHS404,588$1,445,000thousands by filing date
CLENE INC185634102COM118,533$1,333,000thousands by filing date
Eli Lilly and Company532457108COM5,677$1,304,000thousands by filing date
ADICET BIO INC007002108COM125,544$1,291,000thousands by filing date
ANEBULO PHARMACEUTICALS INC034569103COM174,811$1,204,000thousands by filing date
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR8,600$1,132,000thousands by filing datecall
CATABASIS PHARMACEUTICALS IN14875P206COM NEW532,298$1,124,000thousands by filing date
BRAINSTORM CELL THERAPEUTICS10501E201COM293,200$1,115,000thousands by filing date
CORTEXYME INC22053A107COM20,533$1,088,000thousands by filing date
EYEPOINT INC COM NEW30233G209Stock120,135$1,080,000thousands by filing date
MERUS N VN5749R100COM51,223$1,079,000thousands by filing date
REGULUS THERAPEUTICS INC75915K200COM NEW1,245,989$1,014,000thousands by filing date
Tempest Therapeutics, Inc.87978U108Common Stock89,865$1,005,000thousands by filing date
FREQUENCY THERAPEUTICS INC35803L108COM100,800$1,005,000thousands by filing dateput
PANBELA THERAPEUTICS INC69833Q100COM345,013$976,000thousands by filing date
ONCTERNAL THERAPEUTICS INC68236P107COM200,204$950,000thousands by filing date
ATHENEX INC04685N103COM200,000$923,000thousands by filing date
IMMUNOPRECISE ANTIBODIES LTDCOM NEW45257F200cs150,000$903,000thousands by filing date
POSEIDA THERAPEUTICS INC73730P108COM85,837$861,000thousands by filing date
AFFIMED N VN01045108COM93,100$792,000thousands by filing date
BCLS ACQUISITION CORPG0904B105CMN75,100$791,000thousands by filing date
VALLON PHARMACEUTICALS INC92023M101COM140,000$761,000thousands by filing date
STEALTH BIOTHERAPEUTICS CORP SPONSORED ADS85789A105Stock488,014$761,000thousands by filing date
FRAZIER LIFESCIENCES ACQU CORP UNIT EXP 120925G3710A121Stock75,000$756,000thousands by filing date
SEELOS THERAPEUTICS INC81577F109COM279,840$739,000thousands by filing date
INTERCEPT PHARMACEUTICALS IN45845P108COM35,000$700,000thousands by filing date
FREQUENCY THERAPEUTICS INC35803L108COM69,879$696,000thousands by filing date
C4 THERAPEUTICS INC12529R107COM STK17,600$666,000thousands by filing date
ORCHARD THERAPEUTICS PLC68570P101ADR150,000$659,000thousands by filing date
OPUS GENETICS INC67577R102COMMON STOCK119,551$632,000thousands by filing date
IMMUNOVANT INC45258J102COM57,700$610,000thousands by filing dateput
STOKE THERAPEUTICS INC86150R107COM18,000$606,000thousands by filing dateput
CYCLACEL PHARMACE 6percent PFDCONV23254L603Stock100,000$593,000thousands by filing date
AGENUS INC00847G705COM NEW103,843$570,000thousands by filing date
NOVAVAX INC670002401COM NEW2,636$559,000thousands by filing date
ANAPTYSBIO INC032724106COM21,553$558,000thousands by filing date
DELCATH SYSTEMS INC24661P807COMMON STOCK43,915$555,000thousands by filing date
CELLDEX THERAPEUTICS INC NEW15117B202COM NEW16,000$535,000thousands by filing dateput
LARIMAR THERAPEUTICS INC517125100COM52,968$520,000thousands by filing date
PUMA BIOTECHNOLOGY INC74587V107COMMON STOCK54,901$504,000thousands by filing date
OTONOMY INC68906L105COM211,471$472,000thousands by filing date
GENOCEA BIOSCIENCES INC372427401COMMON STOCK200,000$468,000thousands by filing date
ALECTOR INC014442107COMMON STOCK22,300$465,000thousands by filing dateput
ALECTOR INC014442107COMMON STOCK22,300$465,000thousands by filing datecall
FILANA THERAPEUTICS INC14817C107CMN5,362$458,000thousands by filing date
CHIASMA INC16706W102COM90,437$428,000thousands by filing date
CARA THERAPEUTICS INC140755109COM29,335$418,000thousands by filing date
VERICEL CORP92346J108COM7,900$416,000thousands by filing datecall
MEREO BIOPHARMA GROUP PLC589492107CMN944,308$346,000thousands by filing date
APTOSE BIOSCIENCES INC COM03835T200Stock103,904$346,000thousands by filing date
COGENT BIOSCIENCES INC19240Q201COM41,762$338,000thousands by filing date
FATE THERAPEUTICS INC31189P102COM3,600$313,000thousands by filing date
CHARDAN HEALTHCR ACQSTN 2 CO15957T107COM30,000$300,000thousands by filing date
ZAI LAB LTD ADR98887Q104ADR1,600$284,000thousands by filing datecall
ASSEMBLY BIOSCIENCES INC045396108COM72,468$281,000thousands by filing date
CORVUS PHARMACEUTICALS INC221015100COM100,000$267,000thousands by filing date
ASLAN PHARMACEUTICALS LTD04522R101ADR1,224,516$248,000thousands by filing date
INHIBRX INC45720L107COM8,076$222,000thousands by filing date
INVENTIVA SA46124U107ADS15,000$207,000thousands by filing date
GAMIDA CELL LTDM47364100SHS31,166$201,000thousands by filing date
TRAWS PHARMA INC COM NEW68232V801Stock23,226$161,000thousands by filing date
SOLENO THERAPEUTIVS, INC.834203200COMM122,462$140,000thousands by filing date
BAUDAX BIO INC07160F107COM100,000$76,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001420506-21-001161 superseded2021-08-16acceptance time not in the bulk data set
13F-HR/A 0001420506-21-001327this filing2021-08-18acceptance time not in the bulk data set