13F-HR/A filed by Ikarian Capital, LLC
Ikarian Capital, LLC filed this 13F-HR/A for the quarter ended 2021-03-31, filed 2021-08-18, with 291 holding rows worth $2,971,249,000.
- Accession
- 0001420506-21-001325
- Filer
- CIK 1778253
- Filed
- 2021-08-18
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q1 2021
A holdings report, amendment of type restatement, 292 entries on the cover page, a total value of $2,971,249,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $2,971,249,000 with VALUE read as thousands by filing date, 13F file number 028-19721. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| SPY | 78462F103 | SHS | 550,000 | $217,981,000 | thousands by filing date | put |
| ARK ETF TR | 00214Q104 | INNOVATION ETF | 1,100,000 | $131,945,000 | thousands by filing date | put |
| SPDR SER TR | 78464A870 | S&P BIOTECH | 950,000 | $128,866,000 | thousands by filing date | put |
| BIOGEN INC COM | 09062X103 | Stock | 394,900 | $110,475,000 | thousands by filing date | call |
| iShares Russell 2000 ETF | 464287655 | SHS | 450,000 | $99,422,000 | thousands by filing date | put |
| MODERNA INC | 60770K107 | COM | 600,000 | $78,568,000 | thousands by filing date | put |
| ARK ETF TR | 00214Q302 | GENOMIC REV ETF | 854,000 | $75,776,000 | thousands by filing date | put |
| INVESCO QQQ TR | 46090E103 | COM | 200,000 | $63,826,000 | thousands by filing date | put |
| HORIZON THERAPEUTICS PLC | G46188101 | SHS | 632,200 | $58,186,000 | thousands by filing date | call |
| BEONE MEDICINES LTD SPONSORED ADS | 07725L102 | ADR | 160,500 | $55,867,000 | thousands by filing date | put |
| ISHARES TR | 464287432 | 20 YR TR BD ETF | 400,000 | $54,180,000 | thousands by filing date | call |
| SELECT SECTOR SPDR TR | 81369Y704 | INDL | 500,000 | $49,226,000 | thousands by filing date | call |
| SPDR SER TR | 78464A870 | S&P BIOTECH | 350,000 | $47,477,000 | thousands by filing date | call |
| Vertex Pharmaceuticals Incorporated | 92532F100 | COM | 200,000 | $42,977,000 | thousands by filing date | put |
| ISHARES TR | 464287523 | COM | 100,000 | $42,398,000 | thousands by filing date | put |
| ISHARES TR | 464287432 | 20 YR TR BD ETF | 300,000 | $40,635,000 | thousands by filing date | put |
| Financial Select Sector SPDR Fund | 81369Y605 | SHS | 1,109,400 | $37,773,000 | thousands by filing date | call |
| ISHARES TR | 464287556 | ISHARES BIOTECH | 250,000 | $37,640,000 | thousands by filing date | call |
| NOVAVAX INC | 670002401 | COM NEW | 195,700 | $35,483,000 | thousands by filing date | put |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 455,900 | $33,978,000 | thousands by filing date | put |
| CUREVAC N V | N2451R105 | COM | 360,000 | $32,925,000 | thousands by filing date | put |
| BEAM THERAPEUTICS INC | 07373V105 | COM | 360,000 | $28,813,000 | thousands by filing date | put |
| Gilead Sciences,Inc. | 375558103 | COM | 443,600 | $28,668,000 | thousands by filing date | call |
| MIRATI THERAPEUTICS INC | 60468T105 | COM | 162,000 | $27,751,000 | thousands by filing date | put |
| EXACT SCIENCES CORP COM | 30063P105 | Stock | 205,000 | $27,015,000 | thousands by filing date | put |
| CHEMOCENTRYX INC | 16383L106 | COM | 512,000 | $26,235,000 | thousands by filing date | put |
| GW PHARMACEUTICALS PLC | 36197T103 | ADS | 119,100 | $25,833,000 | thousands by filing date | put |
| BAUSCH HEALTH COS INC COM | 071734107 | Stock | 800,000 | $25,392,000 | thousands by filing date | call |
| VANECK ETF TRUST | 92189F676 | COM | 100,000 | $24,354,000 | thousands by filing date | put |
| Eli Lilly and Company | 532457108 | COM | 125,000 | $23,352,000 | thousands by filing date | |
| X4 Pharmaceuticals, Inc. | 98420X103 | COM | 2,614,988 | $22,515,000 | thousands by filing date | |
| TRACON PHARMACEUTICALS INC | 89237H209 | COM NEW | 2,716,840 | $22,360,000 | thousands by filing date | |
| IGM BIOSCIENCES INC | 449585108 | COM | 250,000 | $19,172,000 | thousands by filing date | put |
| SAGE THERAPEUTICS INC | 78667J108 | COM | 250,000 | $18,713,000 | thousands by filing date | put |
| CARA THERAPEUTICS INC | 140755109 | COM | 846,600 | $18,379,000 | thousands by filing date | call |
| UNITED THERAPEUTICS CORP DEL COM | 91307C102 | Stock | 105,000 | $17,562,000 | thousands by filing date | call |
| ASTRAZENECA PLC SPONSORED ADR | 046353108 | ADR | 350,000 | $17,401,000 | thousands by filing date | call |
| ZOGENIX INC. | 98978L204 | Common Stock | 850,000 | $16,591,000 | thousands by filing date | call |
| JAZZ PHARMACEUTICALS PLC SHS USD | G50871105 | Stock | 100,000 | $16,437,000 | thousands by filing date | call |
| INCYTE CORP COM | 45337C102 | Stock | 200,000 | $16,254,000 | thousands by filing date | call |
| MIRATI THERAPEUTICS INC | 60468T105 | COM | 94,500 | $16,188,000 | thousands by filing date | call |
| SERES THERAPEUTICS INC | 81750R102 | COM | 780,000 | $16,061,000 | thousands by filing date | call |
| MACROGENICS INC | 556099109 | COM | 500,469 | $15,940,000 | thousands by filing date | |
| LAKEFRONT BIOTHERAPEUTICS NV | 36315X101 | SPON ADR | 200,000 | $15,513,000 | thousands by filing date | |
| CHIMERIX INC COM | 16934W106 | Stock | 1,597,514 | $15,399,000 | thousands by filing date | |
| Boeing Company | 097023105 | COM | 60,000 | $15,283,000 | thousands by filing date | call |
| ACADIA PHARMACEUTICALS INC | 004225108 | COM | 578,300 | $14,921,000 | thousands by filing date | put |
| TWIST BIOSCIENCE CORP | 90184D100 | COM | 120,000 | $14,864,000 | thousands by filing date | put |
| CURIS INC | 231269200 | COM | 1,220,356 | $13,815,000 | thousands by filing date | |
| MODERNA INC | 60770K107 | COM | 100,000 | $13,094,000 | thousands by filing date | call |
| VIR BIOTECHNOLOGY INC | 92764N102 | COM | 250,000 | $12,816,000 | thousands by filing date | put |
| Utilities Select Sector SPDR Fund | 81369Y886 | SHS | 200,000 | $12,809,000 | thousands by filing date | call |
| NOVAVAX INC | 670002401 | COM NEW | 70,000 | $12,693,000 | thousands by filing date | call |
| 10X GENOMICS INC CL A COM | 88025U109 | Stock | 70,000 | $12,669,000 | thousands by filing date | put |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 596,290 | $12,284,000 | thousands by filing date | |
| CARA THERAPEUTICS INC | 140755109 | COM | 558,524 | $12,125,000 | thousands by filing date | |
| NOVABRIDGE BIOSCIENCES | 44975P103 | CMN | 250,000 | $12,117,000 | thousands by filing date | |
| BLUEPRINT MEDICINES CORP | 09627Y109 | COM | 120,000 | $11,667,000 | thousands by filing date | put |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 640,576 | $11,467,000 | thousands by filing date | |
| INTRA-CELLULAR THERAPIES INC | 46116X101 | COMMON STOCK | 330,989 | $11,231,000 | thousands by filing date | |
| PROTHENA CORP PLC SHS | G72800108 | Stock | 437,430 | $10,989,000 | thousands by filing date | |
| Milestone Pharmaceuticals Inc | 59935V107 | COM | 1,836,545 | $10,633,000 | thousands by filing date | |
| REATA PHARMACEUTICALS INC | 75615P103 | CL A | 104,900 | $10,459,000 | thousands by filing date | put |
| FIBROGEN INC | 31572Q808 | COM | 300,000 | $10,412,000 | thousands by filing date | put |
| ARENA PHARMACEUTICALS INC | 040047607 | COM NEW | 150,000 | $10,408,000 | thousands by filing date | call |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 503,500 | $10,373,000 | thousands by filing date | call |
| CHEMOCENTRYX INC | 16383L106 | COM | 200,000 | $10,248,000 | thousands by filing date | call |
| PROTARA THERAPEUTICS INC | 74365U107 | COM STK | 649,542 | $10,223,000 | thousands by filing date | |
| RELMADA THERAPEUTICS INC | 75955J402 | COMMON STOCK | 290,207 | $10,218,000 | thousands by filing date | |
| VAXCYTE INC COM | 92243G108 | Stock | 501,110 | $9,897,000 | thousands by filing date | |
| GOSSAMER BIO INC COM | 38341P102 | Stock | 1,048,383 | $9,697,000 | thousands by filing date | |
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 34,500 | $9,500,000 | thousands by filing date | put |
| GEMINI THERAPEUTICS INC | 36870G105 | CMN | 684,379 | $9,273,000 | thousands by filing date | |
| CUREVAC N V | N2451R105 | COM | 100,000 | $9,145,000 | thousands by filing date | call |
| LYRA THERAPEUTICS INC | 55234L105 | COM | 780,728 | $9,048,000 | thousands by filing date | |
| FATE THERAPEUTICS INC | 31189P102 | COM | 108,900 | $8,978,000 | thousands by filing date | put |
| SCPHARMACEUTICALS INC | 810648105 | COM | 1,308,699 | $8,703,000 | thousands by filing date | |
| VINCERX PHARMA INC | 92731L106 | COM NEW | 438,684 | $8,467,000 | thousands by filing date | |
| COMPASS PATHWAYS PLC | 20451W101 | SPONSORED ADS | 225,926 | $8,318,000 | thousands by filing date | |
| ASCENDIS PHARMA A/S DKK 1.0 AD | 04351P101 | SPONSORED ADR | 62,090 | $8,001,000 | thousands by filing date | |
| SAGE THERAPEUTICS INC | 78667J108 | COM | 104,300 | $7,805,000 | thousands by filing date | call |
| LAKEFRONT BIOTHERAPEUTICS NV | 36315X101 | SPON ADR | 100,000 | $7,709,000 | thousands by filing date | call |
| ESSA PHARMA INC | 29668H708 | COM NEW | 264,868 | $7,694,000 | thousands by filing date | |
| SIERRA ONCOLOGY INC | 82640U404 | CMN | 445,188 | $7,671,000 | thousands by filing date | |
| INVITAE CORP | 46185L103 | COM | 200,000 | $7,642,000 | thousands by filing date | put |
| KALVISTA PHARMACEUTICALS INC | 483497103 | COM | 296,965 | $7,629,000 | thousands by filing date | |
| SCHRODINGER INC COM | 80810D103 | Stock | 100,000 | $7,628,000 | thousands by filing date | put |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 100,000 | $7,453,000 | thousands by filing date | call |
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 26,900 | $7,407,000 | thousands by filing date | call |
| ADC THERAPEUTICS SA | H0036K147 | COMMON STOCK | 300,000 | $7,323,000 | thousands by filing date | call |
| SERES THERAPEUTICS INC | 81750R102 | COM | 350,000 | $7,206,000 | thousands by filing date | |
| AUTOLUS THERAPEUTICS PLC SPON | 05280R100 | COM | 1,256,048 | $7,196,000 | thousands by filing date | |
| INTRA-CELLULAR THERAPIES INC | 46116X101 | COMMON STOCK | 210,000 | $7,125,000 | thousands by filing date | call |
| RELMADA THERAPEUTICS INC | 75955J402 | COMMON STOCK | 197,600 | $6,958,000 | thousands by filing date | call |
| ARCUS BIOSCIENCES INC | 03969F109 | COM | 245,500 | $6,894,000 | thousands by filing date | put |
| OCULAR THERAPEUTIX INC | 67576A100 | COM | 419,573 | $6,885,000 | thousands by filing date | |
| REVOLUTION MEDICINES INC COM | 76155X100 | Stock | 150,000 | $6,882,000 | thousands by filing date | call |
| SAGE THERAPEUTICS INC | 78667J108 | COM | 91,151 | $6,823,000 | thousands by filing date | |
| ARDELYX INC | 039697107 | COM | 1,030,436 | $6,821,000 | thousands by filing date | |
| VERASTEM INC | 92337C104 | COM | 2,694,394 | $6,655,000 | thousands by filing date | |
| ASCENDIS PHARMA A/S DKK 1.0 AD | 04351P101 | SPONSORED ADR | 50,700 | $6,534,000 | thousands by filing date | call |
| BIOXCEL THERAPEUTICS INC | 09075P105 | COM | 150,000 | $6,474,000 | thousands by filing date | call |
| AGIOS PHARMACEUTICALS INC | 00847X104 | COM | 125,000 | $6,456,000 | thousands by filing date | call |
| MACROGENICS INC | 556099109 | COM | 200,000 | $6,371,000 | thousands by filing date | call |
| ADVISORSHARES TR | 00768Y453 | PURE US CANNABIS | 150,000 | $6,360,000 | thousands by filing date | call |
| IOVANCE BIOTHERAPEUTICS INC | 462260100 | COM | 200,000 | $6,332,000 | thousands by filing date | put |
| LARIMAR THERAPEUTICS INC | 517125100 | COM | 425,384 | $6,215,000 | thousands by filing date | |
| VISTAGEN THERAPEUTICS INC | 92840H202 | COM | 2,885,952 | $6,147,000 | thousands by filing date | |
| IMMUNOVANT INC | 45258J102 | COM | 361,700 | $5,802,000 | thousands by filing date | call |
| HARPOON THERAPEUTICS INC | 41358P106 | COM | 268,600 | $5,619,000 | thousands by filing date | |
| SHATTUCK LABS INC | 82024L103 | COMMON STOCK | 190,330 | $5,566,000 | thousands by filing date | |
| RAPT THERAPEUTICS INC | 75382E109 | COM | 250,000 | $5,550,000 | thousands by filing date | call |
| ANNOVIS BIO INC | 03615A108 | COM | 193,368 | $5,395,000 | thousands by filing date | |
| SYNLOGIC INC | 87166L100 | COM | 1,492,614 | $5,343,000 | thousands by filing date | |
| LIFESCI ACQUISITION II CORP | 53229E103 | COM | 512,450 | $5,196,000 | thousands by filing date | |
| ALECTOR INC | 014442107 | COMMON STOCK | 257,500 | $5,185,000 | thousands by filing date | |
| CRISPR THERAPEUTICS AG NAMEN AKT | H17182108 | Stock | 41,900 | $5,105,000 | thousands by filing date | put |
| FULCRUM THERAPEUTICS INC | 359616109 | COMMON STOCK | 426,739 | $5,026,000 | thousands by filing date | |
| ALLAKOS INC | 01671P100 | COM | 43,000 | $4,935,000 | thousands by filing date | call |
| TG THERAPEUTICS INC COM | 88322Q108 | Stock | 100,000 | $4,820,000 | thousands by filing date | put |
| CLOVIS ONCOLOGY INC | 189464100 | COM | 679,473 | $4,771,000 | thousands by filing date | |
| ACLARIS THERAPEUTICS INC COM | 00461U105 | Stock | 188,200 | $4,742,000 | thousands by filing date | |
| ALLOVIR INC | 019818103 | COM | 200,000 | $4,680,000 | thousands by filing date | call |
| ICAD INC | 44934S206 | COM NEW | 217,637 | $4,618,000 | thousands by filing date | |
| VIKING THERAPEUTICS INC | 92686J106 | COM | 724,754 | $4,584,000 | thousands by filing date | |
| ODONATE THERAPEUTICS INC | 676079106 | COM | 1,336,412 | $4,571,000 | thousands by filing date | |
| SUTRO BIOPHARMA INC | 869367102 | COM | 200,000 | $4,553,000 | thousands by filing date | call |
| NEXTCURE INC | 65343E108 | COM | 453,952 | $4,544,000 | thousands by filing date | |
| OVID THERAPEUTICS INC | 690469101 | COMMON STOCK | 1,124,872 | $4,522,000 | thousands by filing date | |
| CHARDAN HEALTHCR ACQSTN 2 CO | 15957T206 | UNIT 99/99/9999 | 400,000 | $4,399,000 | thousands by filing date | |
| ALLAKOS INC | 01671P100 | COM | 37,700 | $4,327,000 | thousands by filing date | put |
| CABALETTA BIO INC | 12674W109 | COMMON STOCK | 389,384 | $4,323,000 | thousands by filing date | |
| OCULAR THERAPEUTIX INC | 67576A100 | COM | 262,100 | $4,301,000 | thousands by filing date | call |
| PLIANT THERAPEUTICS INC | 729139105 | COM | 108,700 | $4,275,000 | thousands by filing date | |
| C4 THERAPEUTICS INC | 12529R107 | COM STK | 111,500 | $4,124,000 | thousands by filing date | |
| TRANSLATE BIO INC. | 89374L104 | Common Stock | 250,000 | $4,122,000 | thousands by filing date | put |
| ALLOGENE THERAPEUTICS INC | 019770106 | COM | 116,600 | $4,115,000 | thousands by filing date | call |
| TRICIDA INC | 89610F101 | COM | 775,294 | $4,102,000 | thousands by filing date | |
| IONIS PHARMACEUTICALS INC COM | 462222100 | Stock | 90,000 | $4,047,000 | thousands by filing date | call |
| AILERON THERAPEUTICS INC COM NEW | 00887A105 | Stock | 2,800,000 | $4,004,000 | thousands by filing date | |
| SATSUMA PHARMACEUTICALS INC | 80405P107 | COM | 676,294 | $3,997,000 | thousands by filing date | |
| YUMANITY THERAPEUTICS INC | 98872L102 | COM | 219,470 | $3,972,000 | thousands by filing date | |
| STOKE THERAPEUTICS INC | 86150R107 | COM | 102,000 | $3,962,000 | thousands by filing date | put |
| KURA ONCOLOGY INC COM | 50127T109 | Stock | 140,000 | $3,957,000 | thousands by filing date | call |
| ANAPTYSBIO INC | 032724106 | COM | 182,100 | $3,925,000 | thousands by filing date | call |
| IMMUNOVANT INC | 45258J102 | COM | 242,800 | $3,895,000 | thousands by filing date | put |
| CARDIFF ONCOLOGY INC | 14147L108 | COM | 417,900 | $3,870,000 | thousands by filing date | put |
| ONCTERNAL THERAPEUTICS INC | 68236P107 | COM | 460,323 | $3,831,000 | thousands by filing date | |
| DIAMEDICA THERAPEUTICS INC | 25253X207 | COMMON STOCK | 415,000 | $3,797,000 | thousands by filing date | |
| PHATHOM PHARMACEUTICALS INC | 71722W107 | COMMON STOCK | 100,000 | $3,757,000 | thousands by filing date | |
| BLACK DIAMOND THERAPEUTICS I | 09203E105 | COM | 153,941 | $3,735,000 | thousands by filing date | |
| BEONE MEDICINES LTD SPONSORED ADS | 07725L102 | ADR | 10,500 | $3,655,000 | thousands by filing date | call |
| KADMON HLDGS INC | 48283N106 | COM | 936,615 | $3,644,000 | thousands by filing date | |
| ALLAKOS INC | 01671P100 | COM | 31,700 | $3,639,000 | thousands by filing date | |
| SEELOS THERAPEUTICS INC | 81577F109 | COM | 718,284 | $3,585,000 | thousands by filing date | |
| BIOATLA INC | 09077B104 | COM | 70,160 | $3,567,000 | thousands by filing date | |
| SAVARA INC | 805111101 | COM | 1,714,366 | $3,566,000 | thousands by filing date | |
| AERPIO PHARMACEUTICALS INC | 00810B105 | COM | 2,651,093 | $3,420,000 | thousands by filing date | |
| SCHOLAR ROCK HLDG CORP | 80706P103 | COM | 67,059 | $3,397,000 | thousands by filing date | |
| DBV TECHNOLOGIES S A | 23306J101 | ADR | 322,730 | $3,387,000 | thousands by filing date | |
| AMICUS THERAPEUTICS INC | 03152W109 | COM | 341,500 | $3,373,000 | thousands by filing date | |
| BCTG ACQUISITION CORP | 05492W103 | COM | 300,250 | $3,340,000 | thousands by filing date | |
| ACHIEVE LIFE SCIENCES INC | 004468500 | COMMON STOCK | 284,151 | $3,291,000 | thousands by filing date | |
| Mersana Therapeutics Inc | 59045L106 | Common Stock | 200,000 | $3,237,000 | thousands by filing date | call |
| ALPINE IMMUNE SCIENCES INC | 02083G100 | COM | 304,739 | $3,230,000 | thousands by filing date | |
| BLUEBIRD BIO INC | 09609G100 | COM | 106,200 | $3,203,000 | thousands by filing date | call |
| STRONGBRIDGE BIOPHARMA PLC | G85347105 | SHS USD | 1,160,450 | $3,203,000 | thousands by filing date | |
| MORPHIC HLDG INC | 61775R105 | COM | 49,925 | $3,160,000 | thousands by filing date | |
| HIGHCAPE CAP ACQUISITION COR | 42984L105 | COM CL A | 260,000 | $3,099,000 | thousands by filing date | |
| SUTRO BIOPHARMA INC | 869367102 | COM | 135,360 | $3,081,000 | thousands by filing date | |
| CASI PHARMACEUTICALS INC | 14757U109 | COM | 1,268,154 | $3,044,000 | thousands by filing date | |
| TCR2 THERAPEUTICS INC | 87808K106 | COM | 136,486 | $3,013,000 | thousands by filing date | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 127,000 | $2,954,000 | thousands by filing date | |
| CATALYST BIOSCIENCES INC | 14888D208 | COM | 581,200 | $2,929,000 | thousands by filing date | |
| IMMATICS N.V | N44445109 | SHS | 255,138 | $2,860,000 | thousands by filing date | |
| GOSSAMER BIO INC COM | 38341P102 | Stock | 300,000 | $2,775,000 | thousands by filing date | call |
| INMUNE BIO INC | 45782T105 | COM | 233,576 | $2,775,000 | thousands by filing date | |
| MADRIGAL PHARMACEUTICALS INC COM | 558868105 | Stock | 23,654 | $2,768,000 | thousands by filing date | |
| Inflarx Nv | N44821101 | COM | 699,750 | $2,729,000 | thousands by filing date | |
| CERECOR INC | 15671L109 | COM | 897,330 | $2,710,000 | thousands by filing date | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 150,100 | $2,687,000 | thousands by filing date | call |
| ELEDON PHARMACEUTICALS INC | 28617k101 | COM | 250,000 | $2,676,000 | thousands by filing date | |
| NUVATION BIO INC COM CL A | 67080N101 | Stock | 250,000 | $2,613,000 | thousands by filing date | |
| ALTIMMUNE INC | 02155H200 | COM NEW | 181,941 | $2,571,000 | thousands by filing date | |
| LIQUIDIA CORPORATION COM NEW | 53635D202 | Stock | 951,400 | $2,560,000 | thousands by filing date | |
| PASSAGE BIO INC | 702712100 | COM | 145,858 | $2,550,000 | thousands by filing date | |
| INTRA-CELLULAR THERAPIES INC | 46116X101 | COMMON STOCK | 75,000 | $2,545,000 | thousands by filing date | put |
| CATABASIS PHARMACEUTICALS IN | 14875P206 | COM NEW | 852,998 | $2,464,000 | thousands by filing date | |
| ZOGENIX INC. | 98978L204 | Common Stock | 124,091 | $2,422,000 | thousands by filing date | |
| FINCH THERAPEUTICS GROUP INC | 31773D101 | COM | 150,000 | $2,387,000 | thousands by filing date | |
| MERUS N V | N5749R100 | COM | 111,223 | $2,322,000 | thousands by filing date | |
| INTERCEPT PHARMACEUTICALS IN | 45845P108 | COM | 100,000 | $2,308,000 | thousands by filing date | call |
| ZAI LAB LTD ADR | 98887Q104 | ADR | 17,000 | $2,249,000 | thousands by filing date | |
| HEALTH SCIENCES ACQ CORP 2 | G4411D109 | ORD SHS | 200,000 | $2,246,000 | thousands by filing date | |
| TRILLIUM THERAPEUTICS INC COM NEW | 89620X506 | Stock | 200,000 | $2,148,000 | thousands by filing date | call |
| CYCLACEL PHARMACE 6percent PFDCONV | 23254L603 | Stock | 300,000 | $2,133,000 | thousands by filing date | |
| EYEPOINT INC COM NEW | 30233G209 | Stock | 208,500 | $2,116,000 | thousands by filing date | call |
| APPLIED GENETIC TECHNOL CORP | 03820J100 | COM | 415,884 | $2,108,000 | thousands by filing date | |
| ULTRAGENYX PHARMACEUTICAL IN | 90400D108 | COM | 18,400 | $2,094,000 | thousands by filing date | put |
| REGULUS THERAPEUTICS INC | 75915K200 | COM NEW | 1,245,989 | $1,943,000 | thousands by filing date | |
| CHIASMA INC | 16706W102 | COM | 610,299 | $1,909,000 | thousands by filing date | |
| FREQUENCY THERAPEUTICS INC | 35803L108 | COM | 200,000 | $1,900,000 | thousands by filing date | call |
| CORBUS PHARMACEUTICALS HLDGS | 21833P103 | COM | 964,100 | $1,899,000 | thousands by filing date | |
| CLOVER HEALTH INVESTMENTS CO | 18914F103 | COMMON STOCK | 250,000 | $1,890,000 | thousands by filing date | call |
| BELLICUM PHARMACEUTICALS INC COM NEW | 079481404 | Stock | 500,000 | $1,881,000 | thousands by filing date | |
| INCYTE CORP COM | 45337C102 | Stock | 23,012 | $1,870,000 | thousands by filing date | |
| AGENUS INC | 00847G705 | COM NEW | 678,843 | $1,847,000 | thousands by filing date | |
| CRISPR THERAPEUTICS AG NAMEN AKT | H17182108 | Stock | 15,084 | $1,838,000 | thousands by filing date | |
| ORCHARD THERAPEUTICS PLC | 68570P101 | ADR | 250,000 | $1,815,000 | thousands by filing date | |
| ADICET BIO INC | 007002108 | COM | 135,094 | $1,768,000 | thousands by filing date | |
| MUSTANG BIO INC | 62818Q104 | COM | 526,003 | $1,747,000 | thousands by filing date | |
| PDS BIOTECHNOLOGY CORP | 70465T107 | COM | 383,373 | $1,745,000 | thousands by filing date | |
| CEL-SCI CORP | 150837607 | COM PAR NEW | 106,900 | $1,627,000 | thousands by filing date | call |
| MILLENDO THERAPEUTICS INC | 60040X103 | COM | 1,348,021 | $1,617,000 | thousands by filing date | |
| AURIS MEDICAL HOLDING LTD | G07025201 | SHS | 461,522 | $1,605,000 | thousands by filing date | |
| VASCULAR BIOGENICS LTD | M96883109 | COM | 800,811 | $1,601,000 | thousands by filing date | |
| BIOGEN INC COM | 09062X103 | Stock | 5,700 | $1,594,000 | thousands by filing date | |
| BELLUS HEALTH INC NEW | 07987C204 | COM | 400,000 | $1,537,000 | thousands by filing date | |
| CLENE INC | 185634102 | COM | 118,533 | $1,516,000 | thousands by filing date | |
| IMMUNOPRECISE ANTIBODIES LTDCOM NEW | 45257F200 | cs | 150,000 | $1,472,000 | thousands by filing date | |
| CHIMERIX INC COM | 16934W106 | Stock | 150,000 | $1,446,000 | thousands by filing date | call |
| VIRACTA THERAPEUTICS INC | 92765F108 | COM | 155,599 | $1,439,000 | thousands by filing date | |
| SCHOLAR ROCK HLDG CORP | 80706P103 | COM | 28,300 | $1,433,000 | thousands by filing date | call |
| WAVE LIFE SCIENCES LTD SHS | Y95308105 | Stock | 250,000 | $1,403,000 | thousands by filing date | call |
| SORRENTO THERAPEUTICS INC | 83587F202 | COMMON STOCK | 165,900 | $1,372,000 | thousands by filing date | |
| PANBELA THERAPEUTICS INC | 69833Q100 | COM | 345,013 | $1,363,000 | thousands by filing date | |
| ATYR PHARMA INC | 002120202 | COM NEW | 300,000 | $1,336,000 | thousands by filing date | |
| RUBIUS THERAPEUTICS INC | 78116T103 | COM | 50,000 | $1,326,000 | thousands by filing date | |
| AURINIA PHARMACEUTICALS INC COM | 05156V102 | Stock | 100,000 | $1,298,000 | thousands by filing date | call |
| STEALTH BIOTHERAPEUTICS CORP SPONSORED ADS | 85789A105 | Stock | 788,014 | $1,237,000 | thousands by filing date | |
| EYEPOINT INC COM NEW | 30233G209 | Stock | 120,135 | $1,221,000 | thousands by filing date | |
| TELADOC HEALTH INC | 87918A105 | COM | 6,500 | $1,181,000 | thousands by filing date | put |
| ONCONOVA THERAPEUTIC | 68232V405 | Common Stock | 1,145,426 | $1,144,000 | thousands by filing date | |
| CURIS INC | 231269200 | COM | 100,000 | $1,132,000 | thousands by filing date | call |
| BRAINSTORM CELL THERAPEUTICS | 10501E201 | COM | 293,200 | $1,122,000 | thousands by filing date | |
| GAMIDA CELL LTD | M47364100 | SHS | 136,142 | $1,102,000 | thousands by filing date | |
| FREQUENCY THERAPEUTICS INC | 35803L108 | COM | 100,800 | $958,000 | thousands by filing date | put |
| KINIKSA PHARMACEUTICALS LTD | G5269C101 | COM CL A | 51,273 | $949,000 | thousands by filing date | |
| SYNDAX PHARMACEUTICALS INC | 87164F105 | COM | 40,913 | $914,000 | thousands by filing date | |
| AC IMMUNE SA | H00263105 | SHS | 119,803 | $911,000 | thousands by filing date | |
| CYCLERION THERAPEUTICS INC | 23255M105 | COM | 300,000 | $836,000 | thousands by filing date | |
| POSEIDA THERAPEUTICS INC | 73730P108 | COM | 85,837 | $820,000 | thousands by filing date | |
| INTERCEPT PHARMACEUTICALS IN | 45845P108 | COM | 35,000 | $808,000 | thousands by filing date | |
| BCLS ACQUISITION CORP | G0904B105 | CMN | 75,100 | $794,000 | thousands by filing date | |
| CHEMBIO DIAGNOSTICS | 163572209 | COM | 219,109 | $769,000 | thousands by filing date | |
| FRAZIER LIFESCIENCES ACQU CORP UNIT EXP 120925 | G3710A121 | Stock | 75,000 | $766,000 | thousands by filing date | |
| CLOVER HEALTH INVESTMENTS CO | 18914F103 | COMMON STOCK | 100,000 | $757,000 | thousands by filing date | |
| SYROS PHARMACEUTICALS INC | 87184Q107 | COM | 100,000 | $748,000 | thousands by filing date | |
| OPUS GENETICS INC | 67577R102 | COMMON STOCK | 119,551 | $693,000 | thousands by filing date | |
| VALLON PHARMACEUTICALS INC | 92023M101 | COM | 140,000 | $649,000 | thousands by filing date | |
| APTOSE BIOSCIENCES INC COM | 03835T200 | Stock | 103,904 | $622,000 | thousands by filing date | |
| ALBIREO PHARMA INC | 01345P106 | COMMON STOCK | 16,883 | $595,000 | thousands by filing date | |
| ARVINAS INC | 04335A105 | COM | 8,430 | $558,000 | thousands by filing date | |
| DELCATH SYSTEMS INC | 24661P807 | COMMON STOCK | 43,915 | $546,000 | thousands by filing date | |
| FREQUENCY THERAPEUTICS INC | 35803L108 | COM | 56,479 | $536,000 | thousands by filing date | |
| PUMA BIOTECHNOLOGY INC | 74587V107 | COMMON STOCK | 54,901 | $533,000 | thousands by filing date | |
| NOVAVAX INC | 670002401 | COM NEW | 2,636 | $478,000 | thousands by filing date | |
| KURA ONCOLOGY INC COM | 50127T109 | Stock | 15,603 | $441,000 | thousands by filing date | |
| VERICEL CORP | 92346J108 | COM | 7,900 | $439,000 | thousands by filing date | call |
| MEREO BIOPHARMA GROUP PLC | 589492107 | CMN | 1,146,308 | $419,000 | thousands by filing date | |
| SELLAS LIFE SCIENCES GROUP I | 81642T209 | COM NEW | 48,053 | $410,000 | thousands by filing date | |
| Arbutus Biopharma Corp | 03879J100 | Common Shares, without par value | 115,000 | $383,000 | thousands by filing date | |
| COGENT BIOSCIENCES INC | 19240Q201 | COM | 41,762 | $367,000 | thousands by filing date | |
| ASSEMBLY BIOSCIENCES INC | 045396108 | COM | 72,468 | $334,000 | thousands by filing date | |
| CORVUS PHARMACEUTICALS INC | 221015100 | COM | 100,000 | $307,000 | thousands by filing date | |
| CHARDAN HEALTHCR ACQSTN 2 CO | 15957T107 | COM | 30,000 | $301,000 | thousands by filing date | |
| FATE THERAPEUTICS INC | 31189P102 | COM | 3,600 | $297,000 | thousands by filing date | |
| ASLAN PHARMACEUTICALS LTD | 04522R101 | ADR | 1,224,516 | $243,000 | thousands by filing date | |
| BIOXCEL THERAPEUTICS INC | 09075P105 | COM | 5,232 | $226,000 | thousands by filing date | |
| INVENTIVA SA | 46124U107 | ADS | 15,000 | $215,000 | thousands by filing date | |
| GENOCEA BIOSCIENCES INC | 372427401 | COMMON STOCK | 78,767 | $213,000 | thousands by filing date | |
| ANAPTYSBIO INC | 032724106 | COM | 9,553 | $207,000 | thousands by filing date | |
| ARK ETF TR | 00214Q302 | GENOMIC REV ETF | 2,000 | $178,000 | thousands by filing date | |
| INHIBRX INC | 45720L107 | COM | 8,076 | $161,000 | thousands by filing date | |
| ACADIA PHARMACEUTICALS INC | 004225108 | COM | 6,008 | $155,000 | thousands by filing date | |
| SOLENO THERAPEUTIVS, INC. | 834203200 | COMM | 122,462 | $155,000 | thousands by filing date | |
| ARENA PHARMACEUTICALS INC | 040047607 | COM NEW | 2,200 | $153,000 | thousands by filing date | |
| CRYOPORT INC COM PAR $0.001 | 229050307 | Stock | 2,900 | $151,000 | thousands by filing date | |
| SOLID BIOSCIENCES INC COM NEW | 83422E105 | Stock | 23,617 | $131,000 | thousands by filing date | |
| BAUDAX BIO INC | 07160F107 | COM | 100,000 | $129,000 | thousands by filing date | |
| KINNATE BIOPHARMA INC | 49705R105 | COM | 2,000 | $62,000 | thousands by filing date | |
| ROCKET PHARMACEUTICALS INC | 77313F106 | COM | 1,400 | $61,000 | thousands by filing date | |
| REATA PHARMACEUTICALS INC | 75615P103 | CL A | 600 | $60,000 | thousands by filing date | |
| HORIZON THERAPEUTICS PLC | G46188101 | SHS | 603 | $56,000 | thousands by filing date | |
| LEGEND BIOTECH CORP | 52490G102 | SPONSORED ADS | 1,500 | $44,000 | thousands by filing date | put |
| CULLINAN THERAPEUTICS INC | 230031106 | COM | 1,000 | $42,000 | thousands by filing date | |
| IGM BIOSCIENCES INC | 449585108 | COM | 300 | $23,000 | thousands by filing date | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 134 | $10,000 | thousands by filing date | |
| KARYOPHARM THERAPEUTICS INC | 48576U106 | COM | 791 | $9,000 | thousands by filing date | |
| BLUEBIRD BIO INC | 09609G100 | COM | 281 | $8,000 | thousands by filing date | |
| COMPUGEN LTD | M25722105 | ORD | 500 | $4,000 | thousands by filing date | put |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001420506-21-000702 | superseded | 2021-05-17 | acceptance time not in the bulk data set | |
| 13F-HR/A 0001420506-21-001325 | this filing | 2021-08-18 | acceptance time not in the bulk data set |