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13F-HR filed by Ikarian Capital, LLC

Ikarian Capital, LLC filed this 13F-HR for the quarter ended 2020-12-31, filed 2021-02-12, with 230 holding rows worth $2,268,048,000.

Accession
0001420506-21-000255
Filed
2021-02-12
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2020

A holdings report, 230 entries on the cover page, a total value of $2,268,048,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $2,268,048,000 with VALUE read as thousands by filing date, 13F file number 028-19721. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
MODERNA INC60770K107COM1,450,000$151,482,000thousands by filing dateput
SAREPTA THERAPEUTICS INC803607100COM870,900$148,481,000thousands by filing dateput
SPDR SER TR78464A870S&P BIOTECH908,100$127,843,000thousands by filing dateput
BIOGEN INC COM09062X103Stock470,400$115,181,000thousands by filing datecall
SPY78462F103SHS240,000$89,731,000thousands by filing dateput
BIOGEN INC COM09062X103Stock360,000$88,148,000thousands by filing dateput
SAREPTA THERAPEUTICS INC803607100COM501,000$85,416,000thousands by filing datecall
HORIZON THERAPEUTICS PLCG46188101SHS977,200$71,485,000thousands by filing datecall
ARGENX SE SPONSORED ADR04016X101ADR201,500$59,260,000thousands by filing dateput
ARK ETF TR00214Q302GENOMIC REV ETF440,100$41,044,000thousands by filing dateput
NOVAVAX INC670002401COM NEW323,700$36,097,000thousands by filing dateput
TRACON PHARMACEUTICALS INC89237H209COM NEW2,716,840$31,787,000thousands by filing date
CHEMOCENTRYX INC16383L106COM451,700$27,969,000thousands by filing dateput
ZYMEWORKS INC98985W102COM580,200$27,422,000thousands by filing dateput
BIONTECH SE SPONSORED ADS09075V102ADR319,900$26,080,000thousands by filing dateput
BEONE MEDICINES LTD SPONSORED ADS07725L102ADR97,300$25,141,000thousands by filing dateput
CELLDEX THERAPEUTICS INC NEW15117B202COM NEW1,364,990$23,915,000thousands by filing date
IGM BIOSCIENCES INC449585108COM250,000$22,073,000thousands by filing dateput
CUREVAC N VN2451R105COM261,200$21,175,000thousands by filing dateput
REATA PHARMACEUTICALS INC75615P103CL A166,600$20,596,000thousands by filing dateput
KALVISTA PHARMACEUTICALS INC483497103COM1,063,961$20,204,000thousands by filing date
ARVINAS INC04335A105COM232,700$19,763,000thousands by filing datecall
HORIZON THERAPEUTICS PLCG46188101SHS265,000$19,385,000thousands by filing dateput
BEAM THERAPEUTICS INC07373V105COM231,000$18,858,000thousands by filing dateput
Bristol-Myers Squibb Company110122108COM288,400$17,890,000thousands by filing date
ZYMEWORKS INC98985W102COM375,200$17,732,000thousands by filing datecall
CRISPR THERAPEUTICS AG NAMEN AKTH17182108Stock115,300$17,654,000thousands by filing dateput
ASTRAZENECA PLC SPONSORED ADR046353108ADR350,000$17,498,000thousands by filing datecall
Gilead Sciences,Inc.375558103COM300,000$17,478,000thousands by filing datecall
ZOGENIX INC.98978L204Common Stock867,400$17,342,000thousands by filing datecall
MORPHIC HLDG INC61775R105COM516,763$17,338,000thousands by filing date
Eli Lilly and Company532457108COM100,000$16,884,000thousands by filing datecall
IONIS PHARMACEUTICALS INC COM462222100Stock290,000$16,397,000thousands by filing datecall
PROTARA THERAPEUTICS INC74365U107COM STK649,542$15,725,000thousands by filing date
ARROWHEAD PHARMACEUTICALS IN04280A100COM200,000$15,346,000thousands by filing dateput
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR87,090$14,526,000thousands by filing date
PROTHENA CORP PLC SHSG72800108Stock1,186,700$14,252,000thousands by filing date
OCULAR THERAPEUTIX INC67576A100COM684,573$14,171,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM120,000$13,457,000thousands by filing dateput
SUTRO BIOPHARMA INC869367102COM615,360$13,360,000thousands by filing date
CURIS INC231269200COM1,575,000$12,899,000thousands by filing date
ACCELERON PHARMA INC00434H108COM100,000$12,793,000thousands by filing dateput
Milestone Pharmaceuticals Inc59935V107COM1,836,545$12,305,000thousands by filing date
KARUNA THERAPEUTICS INC48576A100COM120,000$12,192,000thousands by filing datecall
VINCERX PHARMA INC92731L106COM NEW538,684$11,265,000thousands by filing date
FIBROGEN INC31572Q808COM300,000$11,126,000thousands by filing datecall
MIRATI THERAPEUTICS INC60468T105COM50,000$10,981,000thousands by filing datecall
CRYOPORT INC COM PAR $0.001229050307Stock250,000$10,970,000thousands by filing datecall
IMMUNOVANT INC45258J102COM235,587$10,882,000thousands by filing date
UNITED THERAPEUTICS CORP DEL COM91307C102Stock69,300$10,520,000thousands by filing datecall
BIOHAVEN PHARMACEUTICAL HOLDING11196105COM119,100$10,208,000thousands by filing datecall
GOSSAMER BIO INC COM38341P102Stock1,048,383$10,138,000thousands by filing date
SPDR SER TR78464A870S&P BIOTECH70,000$9,855,000thousands by filing datecall
BLACK DIAMOND THERAPEUTICS I09203E105COM293,941$9,421,000thousands by filing date
MERUS N VN5749R100COM536,921$9,411,000thousands by filing date
FIBROGEN INC31572Q808COM251,900$9,343,000thousands by filing dateput
KURA ONCOLOGY INC COM50127T109Stock285,000$9,309,000thousands by filing datecall
LYRA THERAPEUTICS INC55234L105COM815,364$9,295,000thousands by filing date
COMPASS PATHWAYS PLC20451W101SPONSORED ADS187,800$8,947,000thousands by filing datecall
INTRA-CELLULAR THERAPIES INC46116X101COMMON STOCK280,989$8,934,000thousands by filing date
BIOHAVEN PHARMACEUTICAL HOLDING11196105COM104,100$8,923,000thousands by filing dateput
VISTAGEN THERAPEUTICS INC92840H202COM4,485,952$8,703,000thousands by filing date
GLOBAL BLOOD THERAPEUTICS USD37890U108COM200,000$8,663,000thousands by filing datecall
ARVINAS INC04335A105COM100,000$8,493,000thousands by filing dateput
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR50,700$8,456,000thousands by filing datecall
SERES THERAPEUTICS INC81750R102COM341,100$8,357,000thousands by filing datecall
ALLAKOS INC01671P100COM58,700$8,218,000thousands by filing datecall
DECIPHERA PHARMACEUTICALS IN24344T101COM140,000$7,989,000thousands by filing datecall
SCPHARMACEUTICALS INC810648105COM1,466,147$7,756,000thousands by filing date
CARDIFF ONCOLOGY INC14147L108COM417,900$7,517,000thousands by filing dateput
ARDELYX INC039697107COM1,155,436$7,476,000thousands by filing date
VAXCYTE INC COM92243G108Stock276,110$7,336,000thousands by filing date
VIR BIOTECHNOLOGY INC92764N102COM268,000$7,176,000thousands by filing dateput
NOVABRIDGE BIOSCIENCES44975P103CMN150,000$7,073,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM81,700$7,069,000thousands by filing datecall
CELLDEX THERAPEUTICS INC NEW15117B202COM NEW400,000$7,008,000thousands by filing datecall
BIOXCEL THERAPEUTICS INC09075P105COM150,000$6,930,000thousands by filing datecall
IMMATICS N.VN44445109SHS638,094$6,885,000thousands by filing date
ALNYLAM PHARMACEUTICALS INC COM02043Q107Stock50,000$6,499,000thousands by filing dateput
MODERNA INC60770K107COM62,059$6,483,000thousands by filing date
OCULAR THERAPEUTIX INC67576A100COM312,100$6,461,000thousands by filing datecall
TRICIDA INC89610F101COM858,908$6,055,000thousands by filing date
SOLID BIOSCIENCES INC COM NEW83422E105Stock788,008$5,973,000thousands by filing date
CHIMERIX INC COM16934W106Stock1,232,513$5,953,000thousands by filing date
STRONGBRIDGE BIOPHARMA PLCG85347105SHS USD2,440,028$5,929,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM66,151$5,723,000thousands by filing date
SCHOLAR ROCK HLDG CORP80706P103COM117,059$5,680,000thousands by filing date
AGIOS PHARMACEUTICALS INC00847X104COM125,000$5,416,000thousands by filing datecall
LIFESCI ACQUISITION II CORP53229E103COM505,000$5,363,000thousands by filing date
X4 Pharmaceuticals, Inc.98420X103COM826,424$5,314,000thousands by filing date
TG THERAPEUTICS INC COM88322Q108Stock100,000$5,202,000thousands by filing dateput
FULCRUM THERAPEUTICS INC359616109COMMON STOCK437,700$5,125,000thousands by filing date
SIERRA ONCOLOGY INC82640U404CMN318,890$5,111,000thousands by filing date
ONCTERNAL THERAPEUTICS INC68236P107COM1,030,323$5,048,000thousands by filing date
C4 THERAPEUTICS INC12529R107COM STK151,500$5,019,000thousands by filing date
VERASTEM INC92337C104COM2,254,591$4,802,000thousands by filing date
CORTEXYME INC22053A107COM170,000$4,722,000thousands by filing dateput
CYTOKINETICS INC23282W605COM NEW227,000$4,718,000thousands by filing date
BLUEBIRD BIO INC09609G100COM106,200$4,595,000thousands by filing datecall
CARA THERAPEUTICS INC140755109COM301,700$4,565,000thousands by filing datecall
QUIDEL CORP74838J101COM25,300$4,545,000thousands by filing datecall
Applied Therapeutics Inc03828A101Common Stock200,000$4,402,000thousands by filing dateput
ARCTURUS THERAPEUTICS HLDGS03969T109COM100,000$4,338,000thousands by filing dateput
CHARDAN HEALTHCR ACQSTN 2 CO15957T206UNIT 99/99/9999400,000$4,236,000thousands by filing date
DIAMEDICA THERAPEUTICS INC25253X207COMMON STOCK415,000$4,208,000thousands by filing date
CURIS INC231269200COM512,500$4,198,000thousands by filing datecall
CARA THERAPEUTICS INC140755109COM273,524$4,137,000thousands by filing date
ANAPTYSBIO INC032724106COM182,100$3,915,000thousands by filing datecall
KADMON HLDGS INC48283N106COM936,615$3,887,000thousands by filing date
FS DEV CORP303020101COM CL A350,000$3,850,000thousands by filing date
TCR2 THERAPEUTICS INC87808K106COM121,486$3,757,000thousands by filing date
INMUNE BIO INC45782T105COM217,568$3,747,000thousands by filing date
CASI PHARMACEUTICALS INC14757U109COM1,268,154$3,741,000thousands by filing date
GOSSAMER BIO INC COM38341P102Stock381,300$3,688,000thousands by filing datecall
FATE THERAPEUTICS INC31189P102COM38,800$3,529,000thousands by filing dateput
FATE THERAPEUTICS INC31189P102COM38,500$3,500,000thousands by filing datecall
PASSAGE BIO INC702712100COM136,697$3,495,000thousands by filing date
ZOGENIX INC.98978L204Common Stock174,091$3,480,000thousands by filing date
XENON PHARMACEUTICALS INC COM98420N105Stock223,173$3,432,000thousands by filing date
SHATTUCK LABS INC82024L103COMMON STOCK65,000$3,406,000thousands by filing date
PHATHOM PHARMACEUTICALS INC71722W107COMMON STOCK100,000$3,321,000thousands by filing date
ARENA PHARMACEUTICALS INC040047607COM NEW42,500$3,265,000thousands by filing datecall
INTRA-CELLULAR THERAPIES INC46116X101COMMON STOCK100,000$3,180,000thousands by filing dateput
CHIASMA INC16706W102COM730,299$3,177,000thousands by filing date
SYNDAX PHARMACEUTICALS INC87164F105COM140,913$3,134,000thousands by filing date
CLOVIS ONCOLOGY INC189464100COM650,000$3,121,000thousands by filing datecall
CYTOKINETICS INC23282W605COM NEW150,000$3,116,000thousands by filing datecall
CLOVIS ONCOLOGY INC189464100COM642,108$3,082,000thousands by filing date
CYCLACEL PHARMACE 6percent PFDCONV23254L603Stock391,450$3,057,000thousands by filing date
FREQUENCY THERAPEUTICS INC35803L108COM85,900$3,028,000thousands by filing dateput
AGENUS INC00847G705COM NEW950,000$3,020,000thousands by filing date
ACADIA PHARMACEUTICALS INC004225108COM56,008$2,995,000thousands by filing date
TRILLIUM THERAPEUTICS INC COM NEW89620X506Stock200,000$2,942,000thousands by filing datecall
Mersana Therapeutics Inc59045L106Common Stock106,000$2,820,000thousands by filing date
LIQUIDIA CORPORATION COM NEW53635D202Stock951,400$2,807,000thousands by filing date
Adverum Biotechnologies, Inc.00773U108Common Stock258,700$2,804,000thousands by filing datecall
KALVISTA PHARMACEUTICALS INC483497103COM145,500$2,761,000thousands by filing datecall
POSEIDA THERAPEUTICS INC73730P108COM250,837$2,752,000thousands by filing date
MADRIGAL PHARMACEUTICALS INC COM558868105Stock23,654$2,630,000thousands by filing date
ICAD INC44934S206COM NEW195,137$2,576,000thousands by filing date
NEKTAR THERAPEUTICS640268108COM150,000$2,550,000thousands by filing datecall
SOCIAL CAP HEDSPIA HLDG CO IG8251K107COM CL A150,000$2,516,000thousands by filing datecall
ADICET BIO INC007002108COM174,277$2,449,000thousands by filing date
PANACEA ACQUISITION CORP698102100CL A201,808$2,361,000thousands by filing date
ACHIEVE LIFE SCIENCES INC004468500COMMON STOCK284,151$2,302,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM23,700$2,272,000thousands by filing datecall
YUMANITY THERAPEUTICS INC98872L102COM132,514$2,253,000thousands by filing date
APPLIED GENETIC TECHNOL CORP03820J100COM545,884$2,232,000thousands by filing date
SYNDAX PHARMACEUTICALS INC87164F105COM100,000$2,224,000thousands by filing datecall
GW PHARMACEUTICALS PLC36197T103ADS19,100$2,204,000thousands by filing dateput
CRYOPORT INC COM PAR $0.001229050307Stock50,000$2,195,000thousands by filing dateput
NEXTCURE INC65343E108COM200,000$2,179,000thousands by filing date
ANAPTYSBIO INC032724106COM100,000$2,149,000thousands by filing date
HARROW INC415858109COM308,607$2,117,000thousands by filing date
DELCATH SYSTEMS INC24661P807COMMON STOCK112,712$2,019,000thousands by filing date
MUSTANG BIO INC62818Q104COM526,003$1,991,000thousands by filing date
ACLARIS THERAPEUTICS INC COM00461U105Stock300,000$1,941,000thousands by filing date
DBV TECHNOLOGIES S A23306J101ADR358,330$1,897,000thousands by filing date
INTRA-CELLULAR THERAPIES INC46116X101COMMON STOCK58,000$1,846,000thousands by filing datecall
KINIKSA PHARMACEUTICALS LTDG5269C101COM CL A101,273$1,789,000thousands by filing date
BELLICUM PHARMACEUTICALS INC COM NEW079481404Stock500,000$1,765,000thousands by filing date
BCTG ACQUISITION CORP05492W103COM149,512$1,711,000thousands by filing date
OTONOMY INC68906L105COM259,337$1,678,000thousands by filing date
SOCIAL CAP HEDSPIA HLDG CO IG8251K107COM CL A100,000$1,677,000thousands by filing date
ATYR PHARMA INC002120202COM NEW400,000$1,552,000thousands by filing date
ACLARIS THERAPEUTICS INC COM00461U105Stock235,800$1,527,000thousands by filing datecall
BIOGEN INC COM09062X103Stock5,700$1,396,000thousands by filing date
CATABASIS PHARMACEUTICALS IN14875P206COM NEW650,000$1,392,000thousands by filing date
AURINIA PHARMACEUTICALS INC COM05156V102Stock100,000$1,383,000thousands by filing datecall
GAMIDA CELL LTDM47364100SHS160,000$1,343,000thousands by filing date
LONGVIEW ACQUISITION CORP543195101COM CL A62,796$1,243,000thousands by filing date
RIGEL PHARMACEUTICALS INC766559603COMMON STOCK345,529$1,209,000thousands by filing date
TRANSPORTATION & LOGISTI438083107COM100,000$1,129,000thousands by filing dateput
COMPASS PATHWAYS PLC20451W101SPONSORED ADS23,648$1,127,000thousands by filing date
SYROS PHARMACEUTICALS INC87184Q107COM100,000$1,085,000thousands by filing date
CHEMBIO DIAGNOSTICS163572209COM219,109$1,041,000thousands by filing date
PUMA BIOTECHNOLOGY INC74587V107COMMON STOCK100,000$1,026,000thousands by filing datecall
CRYOPORT INC COM PAR $0.001229050307Stock22,900$1,004,000thousands by filing date
ALECTOR INC014442107COMMON STOCK57,500$870,000thousands by filing date
ALTIMMUNE INC02155H200COM NEW75,445$851,000thousands by filing date
89BIO INC282559103COM32,799$799,000thousands by filing date
MIRATI THERAPEUTICS INC60468T105COM3,557$781,000thousands by filing date
CORTEXYME INC22053A107COM28,000$776,000thousands by filing datecall
Inflarx NvN44821101COM149,750$754,000thousands by filing date
Applied Therapeutics Inc03828A101Common Stock33,002$726,000thousands by filing date
ALBIREO PHARMA INC01345P106COMMON STOCK16,883$633,000thousands by filing date
KALA BIO INC COM483119103Stock87,813$594,000thousands by filing date
PUMA BIOTECHNOLOGY INC74587V107COMMON STOCK54,901$563,000thousands by filing date
CERECOR INC15671L109COM202,865$536,000thousands by filing date
ARCUS BIOSCIENCES INC03969F109COM20,500$532,000thousands by filing dateput
Adverum Biotechnologies, Inc.00773U108Common Stock44,800$486,000thousands by filing dateput
COGENT BIOSCIENCES INC19240Q201COM41,762$469,000thousands by filing date
AERPIO PHARMACEUTICALS INC00810B105COM475,778$468,000thousands by filing date
BRISTOL-MYERS SQUIBB CO110122157RIGHT 99/99/9999644,021$444,000thousands by filing date
ASSEMBLY BIOSCIENCES INC045396108COM72,468$439,000thousands by filing date
MEREO BIOPHARMA GROUP PLC589492107CMN1,146,308$416,000thousands by filing date
Arbutus Biopharma Corp03879J100Common Shares, without par value115,000$408,000thousands by filing date
ASLAN PHARMACEUTICALS LTD04522R101ADR2,006,451$405,000thousands by filing date
SUNESIS PHARMACEUTICALS INC867328874COM NEW200,000$398,000thousands by filing date
KURA ONCOLOGY INC COM50127T109Stock11,203$366,000thousands by filing date
AVADEL PHARMACEUTICALS, PLC05337M104COMMON STOCK-FO54,694$366,000thousands by filing date
CORTEXYME INC22053A107COM13,000$361,000thousands by filing date
ARVINAS INC04335A105COM4,216$358,000thousands by filing date
RAPT THERAPEUTICS INC75382E109COM15,600$309,000thousands by filing dateput
BELLUS HEALTH INC NEW07987C204COM100,000$306,000thousands by filing date
NOVAVAX INC670002401COM NEW2,636$294,000thousands by filing date
MILLENDO THERAPEUTICS INC60040X103COM135,193$289,000thousands by filing date
PRAXIS PRECISION MEDICINES I74006W108COM5,000$275,000thousands by filing date
INHIBRX INC45720L107COM8,076$266,000thousands by filing date
SOLENO THERAPEUTIVS, INC.834203200COMM122,462$236,000thousands by filing date
INVENTIVA SA46124U107ADS15,000$214,000thousands by filing date
CORBUS PHARMACEUTICALS HLDGS21833P103COM139,100$174,000thousands by filing date
EYEPOINT INC COM NEW30233G209Stock17,900$119,000thousands by filing datecall
BAUDAX BIO INC07160F107COM100,000$101,000thousands by filing date
GLOBAL BLOOD THERAPEUTICS USD37890U108COM2,100$91,000thousands by filing dateput
KINNATE BIOPHARMA INC49705R105COM2,000$79,000thousands by filing date
ROCKET PHARMACEUTICALS INC77313F106COM1,400$75,000thousands by filing date
ZYMEWORKS INC98985W102COM1,556$73,000thousands by filing date
RAPT THERAPEUTICS INC75382E109COM3,500$69,000thousands by filing datecall
TRANSLATE BIO INC.89374L104Common Stock3,600$67,000thousands by filing dateput
ALPINE IMMUNE SCIENCES INC02083G100COM4,739$60,000thousands by filing date
STEALTH BIOTHERAPEUTICS CORP SPONSORED ADS85789A105Stock37,597$57,000thousands by filing date
IGM BIOSCIENCES INC449585108COM300$27,000thousands by filing date
APTOSE BIOSCIENCES INC COM03835T200Stock3,904$18,000thousands by filing date
BLUEBIRD BIO INC09609G100COM281$12,000thousands by filing date
KARYOPHARM THERAPEUTICS INC48576U106COM791$12,000thousands by filing date
COMPUGEN LTDM25722105ORD500$6,000thousands by filing dateput
CHEMOCENTRYX INC16383L106COM37$2,000thousands by filing date
BCLS ACQUISITION CORPG0904B105CMN100$1,000thousands by filing date
GW PHARMACEUTICALS PLC36197T103ADS8$0thousands by filing dateValue filed as zero, left out of ratios.

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001420506-21-000255this filing2021-02-12acceptance time not in the bulk data set