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13F-HR filed by DAFNA Capital Management LLC

DAFNA Capital Management LLC filed this 13F-HR for the quarter ended 2022-09-30, filed 2022-11-14, with 87 holding rows worth $371,806,000.

Accession
0001389933-22-000010
Filed
2022-11-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q3 2022

A holdings report, 87 entries on the cover page, a total value of $371,806,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $371,806,000 with VALUE read as thousands by filing date, 13F file number 028-12327. The quarter's positions are built on this report. The resolved quarter.

Other managers

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
SPDR SER TR78464A870S&P BIOTECH566,000$44,895,000thousands by filing date
STEREOTAXIS INC85916J409COMMON STOCK13,680,554$24,625,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM261,235$17,213,000thousands by filing date
BIOHAVEN PHARMACEUTICAL HOLDING11196105COM110,100$16,644,000thousands by filing date
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR135,712$14,014,000thousands by filing date
XENON PHARMACEUTICALS INC COM98420N105Stock375,223$13,546,000thousands by filing date
ADICET BIO INC007002108COM935,766$13,307,000thousands by filing date
FATE THERAPEUTICS INC31189P102COM539,940$12,100,000thousands by filing date
ISHARES TR464287556ISHARES BIOTECH102,500$11,988,000thousands by filing date
REVOLUTION MEDICINES INC COM76155X100Stock479,785$9,461,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW183,995$8,915,000thousands by filing date
SYNDAX PHARMACEUTICALS INC87164F105COM355,487$8,542,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM80,155$8,513,000thousands by filing date
IDEAYA BIOSCIENCES INC COM45166A102Stock538,561$8,035,000thousands by filing date
EDGEWISE THERAPEUTICS INC28036F105COM781,112$7,686,000thousands by filing date
NURIX THERAPEUTICS INC67080M103COMMON STOCK566,695$7,384,000thousands by filing date
IVERIC BIO INC46583P102COM401,476$7,202,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM180,306$7,061,000thousands by filing date
KARUNA THERAPEUTICS INC48576A100COM28,886$6,497,000thousands by filing date
CYMABAY THERAPEUTICS INC23257D103COM1,703,235$5,961,000thousands by filing date
DEXCOM INC COM252131107Stock72,552$5,843,000thousands by filing date
MERUS N VN5749R100COM276,893$5,546,000thousands by filing date
MORPHIC HLDG INC61775R105COM195,467$5,532,000thousands by filing date
ALECTOR INC014442107COMMON STOCK532,438$5,037,000thousands by filing date
MIRATI THERAPEUTICS INC60468T105COM71,600$5,001,000thousands by filing date
CENTURY THERAPEUTICS INC15673T100COM475,367$4,701,000thousands by filing date
ARCUS BIOSCIENCES INC03969F109COM178,717$4,675,000thousands by filing date
AERIE PHARMACEUTICALS INC00771V108COM307,232$4,648,000thousands by filing date
APELLIS PHARMACEUTICALS INC03753U106COM65,946$4,504,000thousands by filing date
CARDIOVASCULAR SYSTEMS INC141619106COMMON STOCK286,988$3,978,000thousands by filing date
AXOGEN INC05463X106COM332,103$3,959,000thousands by filing date
89BIO INC282559103COM654,862$3,792,000thousands by filing date
KALVISTA PHARMACEUTICALS INC483497103COM255,313$3,705,000thousands by filing date
F-STAR THERAPEUTICS INC30315R107COM576,881$2,954,000thousands by filing date
BICYCLE THERAPEUTICS PLC-ADR088786108SPONSORED ADS122,200$2,842,000thousands by filing date
KURA ONCOLOGY INC COM50127T109Stock206,329$2,818,000thousands by filing date
ATRICURE INC04963C209COM72,029$2,816,000thousands by filing date
Mersana Therapeutics Inc59045L106Common Stock377,763$2,554,000thousands by filing date
MEDIWOUND LTDM68830104ORD SHS1,428,571$1,986,000thousands by filing date
VIGIL NEUROSCIENCE INC92673K108COM216,395$1,969,000thousands by filing date
ACCURAY INC DEL004397105COM941,800$1,959,000thousands by filing date
ITEOS THERAPEUTICS INC46565G104COM97,560$1,859,000thousands by filing date
LARIMAR THERAPEUTICS INC517125100COM574,996$1,840,000thousands by filing date
LAKEFRONT BIOTHERAPEUTICS NV36315X101SPON ADR42,675$1,820,000thousands by filing date
SYROS PHARMACEUTICALS INC87184Q206COM NEW265,878$1,712,000thousands by filing date
DICE THERAPEUTICS INC23345J104COM78,500$1,592,000thousands by filing date
VIKING THERAPEUTICS INC92686J106COM552,400$1,503,000thousands by filing date
AERIE PHARMACEUTICALS INC00771VAB4NOTE 1.500%10/01,500,000$1,476,000thousands by filing dateprincipal
KEROS THERAPEUTICS INC COM492327101Stock39,000$1,467,000thousands by filing date
AFFIMED N VN01045108COM686,282$1,414,000thousands by filing date
ORIC PHARMACEUTICALS INC68622P109COM413,526$1,323,000thousands by filing date
SURFACE ONCOLOGY INC86877M209COM1,100,000$1,144,000thousands by filing date
AUTOLUS THERAPEUTICS PLC SPON05280R100COM496,150$1,062,000thousands by filing date
NEURONETICS INC64131A105COM313,717$998,000thousands by filing date
NGM BIOPHARMACEUTICALS INC62921N105COM74,953$980,000thousands by filing date
GAMIDA CELL LTDM47364100SHS614,896$978,000thousands by filing date
BIOHAVEN LTDG1110E107COM153,564$967,000thousands by filing date
SCYNEXIS INC811292200COM NEW399,064$958,000thousands by filing date
MEREO BIOPHARMA GROUP PLC589492107CMN1,096,513$944,000thousands by filing date
REGULUS THERAPEUTICS INC75915K309COM555,555$944,000thousands by filing date
KINNATE BIOPHARMA INC49705R105COM78,074$933,000thousands by filing date
PARDES BIOSCIENCES INC69945Q105COM479,386$887,000thousands by filing date
BRAINSWAY LTD10501L106CMN220,000$794,000thousands by filing date
GENFIT S A372279109ADS187,940$686,000thousands by filing date
MEI PHARMA INC55279B202COM NEW1,767,146$683,000thousands by filing date
GH RESEARCH PLC ORDINARY SHARESG3855L106Stock52,631$612,000thousands by filing date
MEDICENNA THERAPEUTICS F58490H107FOREIGN CANADIAN660,000$548,000thousands by filing date
BLACK DIAMOND THERAPEUTICS I09203E105COM313,600$530,000thousands by filing date
NEXTCURE INC65343E108COM187,696$516,000thousands by filing date
COMPASS PATHWAYS PLC20451W101SPONSORED ADS47,390$508,000thousands by filing date
PROQR THERAPEUTICS NVN71542109SHS EURO649,383$483,000thousands by filing date
THESEUS PHARMACEUTICALS INC88369M101COM81,899$475,000thousands by filing date
SUTRO BIOPHARMA INC869367102COM81,200$451,000thousands by filing date
IKENA ONCOLOGY INC45175G108COM122,517$435,000thousands by filing date
OTONOMY INC68906L105COM1,470,199$434,000thousands by filing date
COMPASS THERAPEUTICS INC20454B104COM188,094$429,000thousands by filing date
VENUS CONCEPT INC92332W105COM968,187$426,000thousands by filing date
MASIMO CORP COM574795100Stock3,000$423,000thousands by filing date
ADAPTIMMUNE THERAPEUTICS PLC00653A107SPONDS ADR351,064$377,000thousands by filing date
INOGEN INC45780L104COM15,000$364,000thousands by filing date
MACROGENICS INC556099109COM100,000$346,000thousands by filing date
BIOMEA FUSION INC09077A106CMN34,625$339,000thousands by filing date
SPERO THERAPEUTICS INC84833T103COM125,000$250,000thousands by filing date
LINEAGE CELL THERAPEUTICS IN53566P109COMMON STOCK140,000$158,000thousands by filing date
REUNION NEUROSCIENCE INC76134G103COM96,585$138,000thousands by filing date
COMPUGEN LTDM25722105ORD205,202$135,000thousands by filing date
PHASEBIO PHARMACEUTICALS INC717224109COM321,856$57,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001389933-22-000010this filing2022-11-14acceptance time not in the bulk data set