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13F-HR filed by DAFNA Capital Management LLC

DAFNA Capital Management LLC filed this 13F-HR for the quarter ended 2021-12-31, filed 2022-02-14, with 87 holding rows worth $397,677,000.

Accession
0001389933-22-000002
Filed
2022-02-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2021

A holdings report, 87 entries on the cover page, a total value of $397,677,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $397,677,000 with VALUE read as thousands by filing date, 13F file number 028-12327. The quarter's positions are built on this report. The resolved quarter.

Other managers

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
STEREOTAXIS INC85916J409COMMON STOCK13,680,554$84,819,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM206,911$22,162,000thousands by filing date
FATE THERAPEUTICS INC31189P102COM372,160$21,775,000thousands by filing date
ADICET BIO INC007002108COM733,172$12,823,000thousands by filing date
XENON PHARMACEUTICALS INC COM98420N105Stock402,667$12,579,000thousands by filing date
ARENA PHARMACEUTICALS INC040047607COM NEW119,615$11,117,000thousands by filing date
IDEAYA BIOSCIENCES INC COM45166A102Stock460,061$10,876,000thousands by filing date
DEXCOM INC COM252131107Stock18,138$9,739,000thousands by filing date
KARUNA THERAPEUTICS INC48576A100COM72,423$9,487,000thousands by filing date
NURIX THERAPEUTICS INC67080M103COMMON STOCK306,320$8,868,000thousands by filing date
MORPHIC HLDG INC61775R105COM181,467$8,598,000thousands by filing date
BIOHAVEN PHARMACEUTICAL HOLDING11196105COM58,100$8,007,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM180,306$7,670,000thousands by filing date
MERUS N VN5749R100COM226,089$7,190,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM83,655$7,125,000thousands by filing date
SYNDAX PHARMACEUTICALS INC87164F105COM296,535$6,491,000thousands by filing date
ISHARES TR464287556ISHARES BIOTECH40,900$6,242,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW134,094$6,112,000thousands by filing date
CYMABAY THERAPEUTICS INC23257D103COM1,787,569$6,042,000thousands by filing date
CARDIOVASCULAR SYSTEMS INC141619106COMMON STOCK286,988$5,390,000thousands by filing date
REVOLUTION MEDICINES INC COM76155X100Stock212,231$5,342,000thousands by filing date
ATRICURE INC04963C209COM72,029$5,008,000thousands by filing date
ARCUS BIOSCIENCES INC03969F109COM117,200$4,743,000thousands by filing date
MEI PHARMA INC55279B202COM NEW1,764,846$4,712,000thousands by filing date
IVERIC BIO INC46583P102COM275,976$4,614,000thousands by filing date
OTONOMY INC68906L105COM2,200,297$4,577,000thousands by filing date
NATUS MEDICAL INC639050103COM190,635$4,524,000thousands by filing date
ACCURAY INC DEL004397105COM941,800$4,492,000thousands by filing date
RADIUS HEALTH INC750469AA6NOTE4,000,000$3,860,000thousands by filing dateprincipal
PARDES BIOSCIENCES INC69945Q105COM233,500$3,822,000thousands by filing date
F-STAR THERAPEUTICS INC30315R107COM693,785$3,483,000thousands by filing date
ALECTOR INC014442107COMMON STOCK155,247$3,206,000thousands by filing date
AFFIMED N VN01045108COM571,282$3,153,000thousands by filing date
AXOGEN INC05463X106COM332,103$3,112,000thousands by filing date
KALVISTA PHARMACEUTICALS INC483497103COM190,663$2,522,000thousands by filing date
ITEOS THERAPEUTICS INC46565G104COM54,090$2,518,000thousands by filing date
LAKEFRONT BIOTHERAPEUTICS NV36315X101SPON ADR42,675$2,353,000thousands by filing date
BIOMEA FUSION INC09077A106CMN313,923$2,339,000thousands by filing date
RIGEL PHARMACEUTICALS INC766559603COMMON STOCK879,000$2,329,000thousands by filing date
TURNING PT THERAPEUTICS90041T108COM46,452$2,216,000thousands by filing date
ATHIRA PHARMA INC04746L104COM160,983$2,098,000thousands by filing date
VIKING THERAPEUTICS INC92686J106COM447,400$2,058,000thousands by filing date
AERIE PHARMACEUTICALS INC00771V108COM289,040$2,029,000thousands by filing date
COGENT BIOSCIENCES INC19240Q201COM223,554$1,918,000thousands by filing date
89BIO INC282559103COM144,653$1,891,000thousands by filing date
KINNATE BIOPHARMA INC49705R105COM106,453$1,886,000thousands by filing date
MEREO BIOPHARMA GROUP PLC589492107CMN1,126,613$1,803,000thousands by filing date
REGULUS THERAPEUTICS INC75915K200COM NEW5,555,555$1,750,000thousands by filing date
VENUS CONCEPT INC92332W105COM975,687$1,659,000thousands by filing date
CENTURY THERAPEUTICS INC15673T100COM100,135$1,588,000thousands by filing date
KURA ONCOLOGY INC COM50127T109Stock110,829$1,552,000thousands by filing date
BRAINSWAY LTD10501L106CMN200,000$1,540,000thousands by filing date
SURFACE ONCOLOGY INC86877M209COM315,000$1,506,000thousands by filing date
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR11,000$1,480,000thousands by filing date
MACROGENICS INC556099109COM90,000$1,445,000thousands by filing date
NGM BIOPHARMACEUTICALS INC62921N105COM80,485$1,425,000thousands by filing date
NEURONETICS INC64131A105COM313,717$1,399,000thousands by filing date
RADIUS HEALTH INC750469207COM NEW191,978$1,328,000thousands by filing date
AERIE PHARMACEUTICALS INC00771VAB4NOTE 1.500%10/01,500,000$1,243,000thousands by filing dateprincipal
THESEUS PHARMACEUTICALS INC88369M101COM97,500$1,236,000thousands by filing date
WAVE LIFE SCIENCES LTD SHSY95308105Stock390,161$1,225,000thousands by filing date
NEXTCURE INC65343E108COM187,696$1,126,000thousands by filing date
BLACK DIAMOND THERAPEUTICS I09203E105COM206,100$1,099,000thousands by filing date
PHASEBIO PHARMACEUTICALS INC717224109COM378,611$988,000thousands by filing date
MASIMO CORP COM574795100Stock3,000$878,000thousands by filing date
Mersana Therapeutics Inc59045L106Common Stock140,263$872,000thousands by filing date
COMPUGEN LTDM25722105ORD201,502$866,000thousands by filing date
FIELD TRIP HEALTH LTD31656R102COM340,900$839,000thousands by filing date
ASLAN PHARMACEUTICALS LTD04522R101ADR732,500$820,000thousands by filing date
HARPOON THERAPEUTICS INC41358P106COM105,163$794,000thousands by filing date
LAVA THERAPEUTICS NVN51517105SHS139,332$766,000thousands by filing date
LARIMAR THERAPEUTICS INC517125100COM70,177$757,000thousands by filing date
HOOKIPA PHARMA INC43906K100COM320,444$747,000thousands by filing date
SCYNEXIS INC811292200COM NEW121,242$740,000thousands by filing date
PROQR THERAPEUTICS NVN71542109SHS EURO85,476$685,000thousands by filing date
SUTRO BIOPHARMA INC869367102COM45,000$670,000thousands by filing date
COMPASS THERAPEUTICS INC20454B104COM196,091$622,000thousands by filing date
INFINITY PHARMACEUTICALS INC45665G303COM236,160$531,000thousands by filing date
PHARVARIS NVN69605108COMMON STOCK36,720$528,000thousands by filing date
ADAPTIMMUNE THERAPEUTICS PLC00653A107SPONDS ADR136,266$511,000thousands by filing date
INOGEN INC45780L104COM15,000$510,000thousands by filing date
BOLT BIOTHERAPEUTICS INC097702104COM100,000$490,000thousands by filing date
MADRIGAL PHARMACEUTICALS INC COM558868105Stock5,600$475,000thousands by filing date
SURGALIGN HOLDINGS INC86882C105COM579,710$415,000thousands by filing date
ANNEXON INC03589W102COM30,796$354,000thousands by filing date
GENFIT S A372279109ADS60,448$302,000thousands by filing date
LINEAGE CELL THERAPEUTICS IN53566P109COMMON STOCK80,000$196,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001389933-22-000002this filing2022-02-14acceptance time not in the bulk data set