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13F-HR filed by DAFNA Capital Management LLC

DAFNA Capital Management LLC filed this 13F-HR for the quarter ended 2018-12-31, filed 2019-02-14, with 83 holding rows worth $201,092,000.

Accession
0001389933-19-000002
Filed
2019-02-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2018

A holdings report, 83 entries on the cover page, a total value of $201,092,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $201,092,000 with VALUE read as thousands by filing date, 13F file number 028-12327. The quarter's positions are built on this report. The resolved quarter.

Other managers

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
LOXO ONCOLOGY INC548862101COM181,675$25,447,000thousands by filing date
STEREOTAXIS INC85916J409COMMON STOCK13,680,554$14,789,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM104,306$9,991,000thousands by filing date
ATRICURE INC04963C209COM318,729$9,753,000thousands by filing date
NXSTAGE MEDICAL INC67072V103COMMON STOCK312,119$8,933,000thousands by filing date
ISHARES TR464287556ISHARES BIOTECH64,900$6,258,000thousands by filing date
ARGENX SE SPONSORED ADR04016X101ADR58,300$5,601,000thousands by filing date
ZOGENIX INC.98978L204Common Stock143,764$5,242,000thousands by filing date
AERIE PHARMACEUTICALS INC00771V108COM141,770$5,118,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM92,691$4,997,000thousands by filing date
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR77,242$4,839,000thousands by filing date
PROQR THERAPEUTICS NVN71542109SHS EURO272,474$4,300,000thousands by filing date
DEXCOM INC COM252131107Stock34,000$4,073,000thousands by filing date
ALDER BIOPHARMACEUTICALS INC014339105COM396,013$4,059,000thousands by filing date
AKEBIA THERAPEUTICS INC00972D105COMMON STOCK715,538$3,957,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM55,008$3,928,000thousands by filing date
LAKEFRONT BIOTHERAPEUTICS NV36315X101SPON ADR41,609$3,817,000thousands by filing date
BIOCRYST PHARMACEUTICALS INC COM09058V103Stock464,415$3,748,000thousands by filing date
ARENA PHARMACEUTICALS INC040047607COM NEW93,942$3,659,000thousands by filing date
INTEC PHARMA LTD JERUSALEMM53644106SHS463,228$3,493,000thousands by filing date
LUMINEX CORP55027E102COMMON STOCK138,391$3,198,000thousands by filing date
RADIUS HEALTH INC750469AA6NOTE4,000,000$3,064,000thousands by filing dateprincipal
BIOHAVEN PHARMACEUTICAL HOLDING11196105COM80,000$2,958,000thousands by filing date
FOAMIX PHARMACEUTICALS LTDM46135105SHS808,000$2,901,000thousands by filing date
BLUEBIRD BIO INC09609G100COM27,000$2,678,000thousands by filing date
CYMABAY THERAPEUTICS INC23257D103COM332,511$2,617,000thousands by filing date
BIOTELEMETRY INC090672106COM42,800$2,556,000thousands by filing date
MENLO THERAPEUTICS INC586858102COM540,637$2,227,000thousands by filing date
KURA ONCOLOGY INC COM50127T109Stock148,617$2,087,000thousands by filing date
WAVE LIFE SCIENCES LTD SHSY95308105Stock47,900$2,014,000thousands by filing date
CARDIOVASCULAR SYSTEMS INC141619106COMMON STOCK66,200$1,886,000thousands by filing date
CARA THERAPEUTICS INC140755109COM143,611$1,867,000thousands by filing date
TRANSLATE BIO INC.89374L104Common Stock228,939$1,717,000thousands by filing date
INSULET CORP45784PAG6NOTE 1.375%1,500,000$1,590,000thousands by filing dateprincipal
XENON PHARMACEUTICALS INC COM98420N105Stock237,683$1,500,000thousands by filing date
VIKING THERAPEUTICS INC92686J106COM179,200$1,371,000thousands by filing date
INCYTE CORP COM45337C102Stock21,500$1,367,000thousands by filing date
VBI VACCINES INC91822J103COM NEW850,000$1,360,000thousands by filing date
CONCERT PHARMACEUTICALS INC206022105COM105,656$1,326,000thousands by filing date
NATUS MEDICAL INC639050103COM37,900$1,290,000thousands by filing date
ARQULE INC04269E107COM457,664$1,268,000thousands by filing date
DICERNA PHARMACEUTICALS INC253031108COM118,500$1,267,000thousands by filing date
NEVRO CORP64157F103COM31,210$1,214,000thousands by filing date
Johnson & Johnson478160104COM9,400$1,213,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW185,826$1,174,000thousands by filing date
IMMUNOMEDICS INC452907108COM82,254$1,174,000thousands by filing date
ASSEMBLY BIOSCIENCES INC045396108COM50,573$1,144,000thousands by filing date
ACHILLION PHARMACEUTICALS IN00448Q201COM630,182$1,002,000thousands by filing date
MACROGENICS INC556099109COM78,305$994,000thousands by filing date
Arbutus Biopharma Corp03879J100Common Shares, without par value246,900$946,000thousands by filing date
CORBUS PHARMACEUTICALS HLDGS21833P103COM155,000$905,000thousands by filing date
APPLIED GENETIC TECHNOL CORP03820J100COM359,190$894,000thousands by filing date
ARDELYX INC039697107COM472,859$846,000thousands by filing date
MADRIGAL PHARMACEUTICALS INC COM558868105Stock6,600$744,000thousands by filing date
UROGEN PHARMA LTDM96088105COMMON STOCK15,000$646,000thousands by filing date
SCYNEXIS INC COM NEW811292101Common Stock1,272,927$613,000thousands by filing date
ObsEva SAH5861P103COM44,338$561,000thousands by filing date
CIDARA THERAPEUTICS INC COM NEW171757107Stock212,766$500,000thousands by filing date
SPERO THERAPEUTICS INC84833T103COM70,000$431,000thousands by filing date
VALERITAS HLDGS INC91914N202COM NEW1,325,000$431,000thousands by filing date
ALDEYRA THERAPEUTICS INC01438T106COM50,000$415,000thousands by filing date
KALVISTA PHARMACEUTICALS INC483497103COM20,225$399,000thousands by filing date
ZAFGEN INC98885E103COM72,279$358,000thousands by filing date
LEAP THERAPEUTICS INC52187K101COM170,000$340,000thousands by filing date
RADIUS HEALTH INC750469207COM NEW20,500$338,000thousands by filing date
DEXCOM INC252131AF4NOTE 0.750% 5/1250,000$336,000thousands by filing dateprincipal
ARCTURUS THERAPEUTICS LTDM1492T105SHS72,805$330,000thousands by filing date
MASIMO CORP COM574795100Stock3,000$322,000thousands by filing date
ADVAXIS INC007624208COM NEW1,666,666$317,000thousands by filing date
RIGEL PHARMACEUTICALS INC766559603COMMON STOCK137,600$316,000thousands by filing date
PHASEBIO PHARMACEUTICALS INC717224109COM100,000$309,000thousands by filing date
SUTRO BIOPHARMA INC869367102COM31,494$284,000thousands by filing date
APTINYX INC03836N103COM14,500$240,000thousands by filing date
SOL GEL TECHNOLOGIESM8694L103SHS35,000$211,000thousands by filing date
ALDER BIOPHARMACEUTICALS INC014339AA3NOTE 2.500% 2/0250,000$201,000thousands by filing dateprincipal
PROTEOSTASIS THERAPEUTICS IN74373B109COM54,569$177,000thousands by filing date
MINERVA NEUROSCIENCES INC COM NEW603380106Stock26,084$176,000thousands by filing date
KADMON HLDGS INC48283N106COM65,500$136,000thousands by filing date
Bowater Inc09066L105COMMON STOCKS100,000$91,000thousands by filing date
BELLICUM PHARMACEUTICALS INC079481107COM30,000$88,000thousands by filing date
DERMIRA INC24983L104COM10,000$72,000thousands by filing date
ORAMED PHARMACEUTICALS INC68403P203COM NEW16,000$48,000thousands by filing date
NEOS THERAPEUTICS INC64052L106COM27,500$45,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001389933-19-000002this filing2019-02-14acceptance time not in the bulk data set