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13F-HR filed by DAFNA Capital Management LLC

DAFNA Capital Management LLC filed this 13F-HR for the quarter ended 2017-12-31, filed 2018-02-14, with 72 holding rows worth $185,688,000.

Accession
0001389933-18-000002
Filed
2018-02-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2017

A holdings report, 72 entries on the cover page, a total value of $185,688,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $185,688,000 with VALUE read as thousands by filing date, 13F file number 028-12327. The quarter's positions are built on this report. The resolved quarter.

Other managers

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
LOXO ONCOLOGY INC548862101COM296,000$24,917,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM100,691$7,593,000thousands by filing date
ATRICURE INC04963C209COM389,145$7,098,000thousands by filing date
AERIE PHARMACEUTICALS INC00771V108COM116,770$6,977,000thousands by filing date
ARGENX SE SPONSORED ADR04016X101ADR95,396$6,023,000thousands by filing date
BEONE MEDICINES LTD SPONSORED ADS07725L102ADR61,349$5,995,000thousands by filing date
BIOCRYST PHARMACEUTICALS INC COM09058V103Stock1,193,228$5,859,000thousands by filing date
ZOGENIX INC.98978L204Common Stock134,147$5,373,000thousands by filing date
NXSTAGE MEDICAL INC67072V103COMMON STOCK216,119$5,237,000thousands by filing date
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR124,639$4,993,000thousands by filing date
IMMUNOMEDICS INC452907108COM304,000$4,913,000thousands by filing date
DEXCOM INC COM252131107Stock83,000$4,763,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM28,800$4,744,000thousands by filing date
VBI VACCINES INC91822J103COM NEW998,000$4,261,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM54,508$4,229,000thousands by filing date
ALDER BIOPHARMACEUTICALS INC014339105COM346,013$3,962,000thousands by filing date
RIGEL PHARMACEUTICALS INC766559603COMMON STOCK983,478$3,816,000thousands by filing date
RADIUS HEALTH INC750469AA6NOTE4,000,000$3,758,000thousands by filing dateprincipal
LAKEFRONT BIOTHERAPEUTICS NV36315X101SPON ADR39,609$3,714,000thousands by filing date
CYMABAY THERAPEUTICS INC23257D103COM361,164$3,323,000thousands by filing date
MACROGENICS INC556099109COM154,200$2,930,000thousands by filing date
SUNESIS PHARMACEUTICALS INC867328700COM783,000$2,889,000thousands by filing date
ISHARES TR464287556ISHARES BIOTECH26,100$2,787,000thousands by filing date
ACHILLION PHARMACEUTICALS IN00448Q201COM948,272$2,731,000thousands by filing date
BIOTELEMETRY INC090672106COM88,100$2,634,000thousands by filing date
VOYAGER THERAPEUTICS INC92915B106COMMON STOCK157,000$2,606,000thousands by filing date
DERMIRA INC24983L104COM86,000$2,392,000thousands by filing date
INSULET CORP COM45784P101Stock32,484$2,241,000thousands by filing date
PROTALIX BIOTHERAPEUTICS INC74365AAB7NOTE 4.500% 9/12,500,000$2,125,000thousands by filing dateprincipal
FOAMIX PHARMACEUTICALS LTDM46135105SHS352,741$2,120,000thousands by filing date
AKEBIA THERAPEUTICS INC00972D105COMMON STOCK135,738$2,018,000thousands by filing date
AEGLEA BIOTHERAPEUTICS INC00773J103COM349,592$1,891,000thousands by filing date
ARDELYX INC039697107COM275,059$1,815,000thousands by filing date
KURA ONCOLOGY INC COM50127T109Stock117,281$1,794,000thousands by filing date
RADIUS HEALTH INC750469207COM NEW53,309$1,694,000thousands by filing date
DERMIRA INC24983LAA2NOTE 3.000% 5/11,500,000$1,646,000thousands by filing dateprincipal
APPLIED GENETIC TECHNOL CORP03820J100COM421,000$1,516,000thousands by filing date
INSULET CORP45784PAG6NOTE 1.375%1,500,000$1,515,000thousands by filing dateprincipal
CIDARA THERAPEUTICS INC COM NEW171757107Stock216,403$1,472,000thousands by filing date
AQUINOX PHARMACEUTICALS INC03842B101COM118,928$1,399,000thousands by filing date
EXACTECH INC30064E109COM27,532$1,361,000thousands by filing date
Johnson & Johnson478160104COM9,400$1,313,000thousands by filing date
IMMUNE DESIGN CORP.45252L103Common Stock328,500$1,281,000thousands by filing date
SCPHARMACEUTICALS INC810648105COM98,100$1,186,000thousands by filing date
SCYNEXIS INC COM NEW811292101Common Stock506,900$1,176,000thousands by filing date
ARQULE INC04269E107COM697,192$1,150,000thousands by filing date
CARA THERAPEUTICS INC140755109COM93,800$1,148,000thousands by filing date
CLEMENTIA PHARMACEUTICALS IN185575107COM60,000$1,139,000thousands by filing date
STEREOTAXIS INC85916J409COMMON STOCK1,372,862$1,098,000thousands by filing date
XENON PHARMACEUTICALS INC COM98420N105Stock377,695$1,067,000thousands by filing date
MINERVA NEUROSCIENCES INC COM NEW603380106Stock171,094$1,035,000thousands by filing date
COGENTIX MED INC COM19243A104Stock323,482$1,019,000thousands by filing date
PROQR THERAPEUTICS NVN71542109SHS EURO230,770$744,000thousands by filing date
ADVAXIS INC007624208COM NEW247,000$701,000thousands by filing date
PROTEOSTASIS THERAPEUTICS IN74373B109COM117,500$685,000thousands by filing date
LEAP THERAPEUTICS INC52187K101COM108,330$676,000thousands by filing date
IRONWOOD PHARMACEUTICALS INC46333XAD0DBCV 2.250% 6/1573,000$670,000thousands by filing dateprincipal
Bowater Inc09066L105COMMON STOCKS275,000$591,000thousands by filing date
LUMINEX CORP55027E102COMMON STOCK25,000$493,000thousands by filing date
INOTEK PHARMACEUTICALS CORP45780VAB8NOTE 5.750% 8/0600,000$452,000thousands by filing dateprincipal
MASIMO CORP COM574795100Stock5,000$424,000thousands by filing date
CASCADIAN THERAPEUTICS INC14740B606COM NEW106,810$395,000thousands by filing date
BLUEBIRD BIO INC09609G100COM2,000$356,000thousands by filing date
NATUS MEDICAL INC639050103COM7,900$302,000thousands by filing date
NEOS THERAPEUTICS INC64052L106COM27,500$281,000thousands by filing date
DEXCOM INC252131AE7DBCV 0.750% 5/1250,000$236,000thousands by filing dateprincipal
DECIPHERA PHARMACEUTICALS IN24344T101COM9,619$218,000thousands by filing date
EDGE THERAPEUTICS INC279870109COM19,400$182,000thousands by filing date
REDHILL BIOPHARMA LTD757468103ADR35,000$180,000thousands by filing date
BELLICUM PHARMACEUTICALS INC079481107COM20,000$168,000thousands by filing date
ObsEva SAH5861P103COM14,225$139,000thousands by filing date
SPERO THERAPEUTICS INC84833T103COM5,000$59,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001389933-18-000002this filing2018-02-14acceptance time not in the bulk data set