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Disclosery

13F-HR/A filed by Palo Alto Investors LP

Palo Alto Investors LP filed this 13F-HR/A for the quarter ended 2023-12-31, filed 2024-02-15, with 34 holding rows worth $1,109,907,525.

Accession
0001306923-24-000007
Filer
CIK 1306923
Filed
2024-02-15
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2023

A holdings report, amendment of type restatement, 34 entries on the cover page, a total value of $1,109,907,525 stated on the cover page (in dollars after the unit check, H1), rows summing to $1,109,907,525 with VALUE read as dollars as filed, 13F file number 028-11013. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
INSMED INC COM PAR $.01457669307Stock5,511,721$170,808,234dollars as filed
AMICUS THERAPEUTICS INC03152W109COM10,373,715$147,203,016dollars as filed
BIOMARIN PHARMACEUTICAL INC09061G101COM1,500,749$144,702,219dollars as filed
BIOGEN INC COM09062X103Stock380,417$98,440,507dollars as filed
UNITED THERAPEUTICS CORP DEL COM91307C102Stock395,784$87,028,944dollars as filed
ACADIA PHARMACEUTICALS INC004225108COM2,409,556$75,443,198dollars as filed
PROTHENA CORP PLC SHSG72800108Stock1,660,057$60,326,471dollars as filed
REVANCE THERAPEUTICS INC761330109COM5,237,284$46,035,726dollars as filed
STAAR SURGICAL CO COM PAR $0.01852312305Stock1,376,950$42,974,610dollars as filed
ALNYLAM PHARMACEUTICALS INC COM02043Q107Stock154,437$29,560,786dollars as filed
EHEALTH INC28238P109COM2,739,379$23,887,385dollars as filed
SAGE THERAPEUTICS INC78667J108COM991,525$21,486,347dollars as filed
SAREPTA THERAPEUTICS INC803607100COM200,905$19,373,269dollars as filed
IOVANCE BIOTHERAPEUTICS INC462260100COM2,106,792$17,128,219dollars as filed
ALKERMES PLCG01767105SHS603,400$16,738,316dollars as filed
NEVRO CORP64157F103COM750,371$16,147,984dollars as filed
ALIGN TECHNOLOGY INC COM016255101Stock55,705$15,263,170dollars as filed
ANAPTYSBIO INC032724106COM686,882$14,713,012dollars as filed
SYNDAX PHARMACEUTICALS INC87164F105COM472,600$10,212,886dollars as filed
CYTOKINETICS INC23282W605COM NEW111,717$9,327,252dollars as filed
NOVOCURE LTDG6674U108ORD SHS561,908$8,389,286dollars as filed
VERVE THERAPEUTICS INC92539P101COM575,817$8,026,889dollars as filed
GOSSAMER BIO INC COM38341P102Stock5,958,888$6,530,288dollars as filed
BLUEBIRD BIO INC09609G100COM3,333,333$4,600,000dollars as filed
KARYOPHARM THERAPEUTICS INC48576U106COM5,102,193$4,413,397dollars as filed
RELMADA THERAPEUTICS INC75955J402COMMON STOCK732,400$3,032,136dollars as filed
MIRUM PHARMACEUTICALS INC604749101COM64,700$1,909,944dollars as filed
VANDA PHARMACEUTICALS INC921659108COM278,985$1,177,317dollars as filed
VYNE THERAPEUTICS INC92941V308COM445,434$1,037,861dollars as filed
TRAVERE THERAPEUTICS INC89422G107COM110,719$995,364dollars as filed
TAYSHA GENE THERAPIES INC877619106COMMON STOCK529,861$937,854dollars as filed
SIGHT SCIENCES INC82657M105COMMON STOCK173,790$896,756dollars as filed
ALDEYRA THERAPEUTICS INC01438T106COM225,465$791,382dollars as filed
UROGEN PHARMA LTDM96088105COMMON STOCK24,500$367,500dollars as filed

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001306923-24-000002 superseded2024-02-14acceptance time not in the bulk data set
13F-HR/A 0001306923-24-000007this filing2024-02-15acceptance time not in the bulk data set