13F-HR filed by Palo Alto Investors LP
Palo Alto Investors LP filed this 13F-HR for the quarter ended 2021-12-31, filed 2022-02-14, with 37 holding rows worth $1,564,771,000.
- Accession
- 0001306923-22-000004
- Filer
- CIK 1306923
- Filed
- 2022-02-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2021
A holdings report, 37 entries on the cover page, a total value of $1,564,771,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $1,564,771,000 with VALUE read as thousands by filing date, 13F file number 028-11013. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| BIOMARIN PHARMACEUTICAL INC | 09061G101 | COM | 2,212,950 | $195,514,000 | thousands by filing date | |
| ABIOMED INC | 003654100 | COM | 519,033 | $186,421,000 | thousands by filing date | |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 6,025,706 | $164,140,000 | thousands by filing date | |
| UNITED THERAPEUTICS CORP DEL COM | 91307C102 | Stock | 687,206 | $148,491,000 | thousands by filing date | |
| AMICUS THERAPEUTICS INC | 03152W109 | COM | 10,114,043 | $116,817,000 | thousands by filing date | |
| STAAR SURGICAL CO COM PAR $0.01 | 852312305 | Stock | 1,140,511 | $104,129,000 | thousands by filing date | |
| BIOGEN INC COM | 09062X103 | Stock | 385,000 | $92,369,000 | thousands by filing date | |
| PROTHENA CORP PLC SHS | G72800108 | Stock | 1,685,282 | $83,253,000 | thousands by filing date | |
| REVANCE THERAPEUTICS INC | 761330109 | COM | 4,369,366 | $71,308,000 | thousands by filing date | |
| ACADIA PHARMACEUTICALS INC | 004225108 | COM | 2,337,877 | $54,566,000 | thousands by filing date | |
| VANDA PHARMACEUTICALS INC | 921659108 | COM | 2,834,244 | $44,469,000 | thousands by filing date | |
| EHEALTH INC | 28238P109 | COM | 1,615,570 | $41,197,000 | thousands by filing date | |
| ALIGN TECHNOLOGY INC COM | 016255101 | Stock | 55,405 | $36,411,000 | thousands by filing date | |
| KARYOPHARM THERAPEUTICS INC | 48576U106 | COM | 5,470,452 | $35,175,000 | thousands by filing date | |
| SAGE THERAPEUTICS INC | 78667J108 | COM | 781,730 | $33,255,000 | thousands by filing date | |
| GRITSTONE BIO INC | 39868T105 | COM | 2,356,282 | $30,302,000 | thousands by filing date | |
| GOSSAMER BIO INC COM | 38341P102 | Stock | 1,772,950 | $20,052,000 | thousands by filing date | |
| ALKERMES PLC | G01767105 | SHS | 754,200 | $17,543,000 | thousands by filing date | |
| ANAPTYSBIO INC | 032724106 | COM | 436,592 | $15,172,000 | thousands by filing date | |
| EPIZYME INC | 29428V104 | COM | 5,485,213 | $13,713,000 | thousands by filing date | |
| SYNDAX PHARMACEUTICALS INC | 87164F105 | COM | 598,900 | $13,110,000 | thousands by filing date | |
| KEZAR LIFE SCIENCES INC | 49372L100 | COM | 656,200 | $10,972,000 | thousands by filing date | |
| CLOVIS ONCOLOGY INC | 189464100 | COM | 3,997,826 | $10,834,000 | thousands by filing date | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 123,686 | $5,638,000 | thousands by filing date | |
| TRAVERE THERAPEUTICS INC | 89422G107 | COM | 166,069 | $5,155,000 | thousands by filing date | |
| ZOGENIX INC. | 98978L204 | Common Stock | 183,800 | $2,987,000 | thousands by filing date | |
| DIANTHUS THERAPEUTICS INC COM | 55910K108 | Stock | 432,300 | $1,915,000 | thousands by filing date | |
| NOVAVAX INC | 670002401 | COM NEW | 12,500 | $1,788,000 | thousands by filing date | |
| RIGEL PHARMACEUTICALS INC | 766559603 | COMMON STOCK | 652,395 | $1,729,000 | thousands by filing date | |
| ASTRAZENECA PLC SPONSORED ADR | 046353108 | ADR | 29,260 | $1,704,000 | thousands by filing date | |
| MIRUM PHARMACEUTICALS INC | 604749101 | COM | 64,700 | $1,032,000 | thousands by filing date | |
| ALIMERA SCIENCES INC | 016259202 | COM | 200,919 | $1,031,000 | thousands by filing date | |
| KALEIDO BIOSCIENCES INC | 483347100 | COM | 341,030 | $815,000 | thousands by filing date | |
| ALDEYRA THERAPEUTICS INC | 01438T106 | COM | 160,800 | $643,000 | thousands by filing date | |
| TACTILE SYSTEMS TECHNOLOGY I | 87357P100 | COMMON STOCK | 27,100 | $516,000 | thousands by filing date | |
| MARINUS PHARMACEUTICALS INC | 56854Q200 | COM NEW | 31,330 | $372,000 | thousands by filing date | |
| UROGEN PHARMA LTD | M96088105 | COMMON STOCK | 24,500 | $233,000 | thousands by filing date |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001306923-22-000004 | this filing | 2022-02-14 | acceptance time not in the bulk data set |