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13F-HR filed by Palo Alto Investors LP

Palo Alto Investors LP filed this 13F-HR for the quarter ended 2019-12-31, filed 2020-02-14, with 37 holding rows worth $1,816,265,000.

Accession
0001306923-20-000013
Filed
2020-02-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2019

A holdings report, 37 entries on the cover page, a total value of $1,816,265,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $1,816,265,000 with VALUE read as thousands by filing date, 13F file number 028-11013. A later restatement replaced it, so the quarter does not use it. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
BIOMARIN PHARMACEUTICAL INC09061G101COM2,021,136$170,887,000thousands by filing date
INSMED INC COM PAR $.01457669307Stock6,848,760$163,548,000thousands by filing date
EPIZYME INC29428V104COM6,145,945$151,190,000thousands by filing date
STAAR SURGICAL CO COM PAR $0.01852312305Stock3,778,938$132,905,000thousands by filing date
IMMUNOGEN INC45253H101COMMON STOCK5,923,195$125,335,000thousands by filing date
UNITED THERAPEUTICS CORP DEL COM91307C102Stock1,288,902$113,526,000thousands by filing date
AIMMUNE THERAPEUTICS INC.00900T107Common Stock3,380,441$113,143,000thousands by filing date
ABIOMED INC003654100COM564,168$96,241,000thousands by filing date
ALEXION PHARMACEUTICALS INC015351109COM878,100$94,967,000thousands by filing date
KARYOPHARM THERAPEUTICS INC48576U106COM4,595,001$88,086,000thousands by filing date
ACADIA PHARMACEUTICALS INC004225108COM1,905,374$81,512,000thousands by filing date
WRIGHT MED GROUP N VN96617118ORD SHS2,463,055$75,074,000thousands by filing date
VANDA PHARMACEUTICALS INC921659108COM4,525,476$74,263,000thousands by filing date
AMICUS THERAPEUTICS INC03152W109COM7,413,920$72,212,000thousands by filing date
CLOVIS ONCOLOGY INC189464100COM5,056,286$52,712,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM653,594$47,183,000thousands by filing date
AMAG PHARMACEUTICALS INC00163U106COM3,044,374$37,050,000thousands by filing date
ALIGN TECHNOLOGY INC COM016255101Stock127,505$35,579,000thousands by filing date
MOMENTA PHARMACEUTICALS INC60877T100COM1,685,372$33,252,000thousands by filing date
PROTHENA CORP PLC SHSG72800108Stock992,749$15,715,000thousands by filing date
PUMA BIOTECHNOLOGY INC74587V107COMMON STOCK1,349,180$11,805,000thousands by filing date
RIGEL PHARMACEUTICALS INC766559603COMMON STOCK3,542,551$7,581,000thousands by filing date
DICERNA PHARMACEUTICALS INC253031108COM331,813$7,310,000thousands by filing date
KALEIDO BIOSCIENCES INC483347100COM787,999$3,956,000thousands by filing date
Gilead Sciences,Inc.375558103COM39,300$2,554,000thousands by filing date
ZOGENIX INC.98978L204Common Stock29,500$1,538,000thousands by filing date
ALIMERA SCIENCES INC016259103COM200,919$1,523,000thousands by filing date
REVANCE THERAPEUTICS INC761330109COM88,590$1,438,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW123,686$1,312,000thousands by filing date
INTRA-CELLULAR THERAPIES INC46116X101COMMON STOCK37,400$1,283,000thousands by filing date
ALDEYRA THERAPEUTICS INC01438T106COM73,500$427,000thousands by filing date
SUNESIS PHARMACEUTICALS INC867328700COM1,162,473$393,000thousands by filing date
MARINUS PHARMACEUTICALS INC56854Q101COM125,321$271,000thousands by filing date
MINERVA NEUROSCIENCES INC COM NEW603380106Stock36,319$258,000thousands by filing date
IDERA PHARMACEUTICALS INC45168K405COM PAR77,044$140,000thousands by filing date
SOPHIRIS BIO INC F83578Q209FOREIGN CANADIAN247,000$91,000thousands by filing date
Melinta Therapeutics Inc58549G209Common / Ordinary Stock10,137$5,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001306923-20-000013this filing2020-02-14acceptance time not in the bulk data set
13F-HR/A 0001306923-20-000014 base2020-04-08acceptance time not in the bulk data set