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13F-HR filed by Palo Alto Investors LP

Palo Alto Investors LP filed this 13F-HR for the quarter ended 2017-09-30, filed 2017-11-14, with 40 holding rows worth $2,374,127,000.

Accession
0001306923-17-000025
Filed
2017-11-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q3 2017

A holdings report, 40 entries on the cover page, a total value of $2,374,127,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $2,374,127,000 with VALUE read as thousands by filing date, 13F file number 028-11013. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
ABIOMED INC003654100COM1,935,300$326,292,000thousands by filing date
CLOVIS ONCOLOGY INC189464100COM3,329,581$274,357,000thousands by filing date
BIOMARIN PHARMACEUTICAL INC09061G101COM2,438,519$226,953,000thousands by filing date
UNITED THERAPEUTICS CORP DEL COM91307C102Stock1,762,650$206,565,000thousands by filing date
INSMED INC COM PAR $.01457669307Stock6,171,816$192,622,000thousands by filing date
ALEXION PHARMACEUTICALS INC015351109COM1,080,342$151,561,000thousands by filing date
EPIZYME INC29428V104COM6,398,296$121,888,000thousands by filing date
AMICUS THERAPEUTICS INC03152W109COM7,420,288$111,898,000thousands by filing date
VANDA PHARMACEUTICALS INC921659108COM4,155,670$74,386,000thousands by filing date
PROTHENA CORP PLC SHSG72800108Stock1,095,655$70,966,000thousands by filing date
WRIGHT MED GROUP N VN96617118ORD SHS2,676,393$69,238,000thousands by filing date
AMAG PHARMACEUTICALS INC00163U106COM3,441,233$63,491,000thousands by filing date
ACADIA PHARMACEUTICALS INC004225108COM1,641,030$61,818,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM787,251$49,046,000thousands by filing date
STAAR SURGICAL CO COM PAR $0.01852312305Stock3,507,052$43,663,000thousands by filing date
CELGENE CORP151020104COM295,240$43,052,000thousands by filing date
IMMUNOMEDICS INC452907108COM3,010,466$42,086,000thousands by filing date
ALIGN TECHNOLOGY INC COM016255101Stock223,107$41,558,000thousands by filing date
KARYOPHARM THERAPEUTICS INC48576U106COM3,498,585$38,414,000thousands by filing date
MOMENTA PHARMACEUTICALS INC60877T100COM1,794,998$33,207,000thousands by filing date
AIMMUNE THERAPEUTICS INC.00900T107Common Stock1,293,764$32,072,000thousands by filing date
EXACT SCIENCES CORP COM30063P105Stock433,076$20,407,000thousands by filing date
SHIRE PLC82481R106COMMON STOCK-FO130,200$19,939,000thousands by filing date
Gilead Sciences,Inc.375558103COM175,900$14,251,000thousands by filing date
BIOVERATIV INC09075E100COM211,300$12,059,000thousands by filing date
RIGEL PHARMACEUTICALS INC766559603COMMON STOCK3,855,024$9,792,000thousands by filing date
ACELRX PHARMACEUTICALS INC00444T100COM1,032,715$4,750,000thousands by filing date
ALIMERA SCIENCES INC016259103COM3,013,793$4,069,000thousands by filing date
DICERNA PHARMACEUTICALS INC253031108COM500,913$2,880,000thousands by filing date
SUNESIS PHARMACEUTICALS INC867328700COM1,162,473$2,255,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW123,686$1,793,000thousands by filing date
IDERA PHARMACEUTICALS INC45168K306COM616,355$1,374,000thousands by filing date
CEMPRA INC15130J109COM340,320$1,106,000thousands by filing date
ZOGENIX INC.98978L204Common Stock29,500$1,034,000thousands by filing date
TREVENA INC89532E109COM341,300$870,000thousands by filing date
ALDER BIOPHARMACEUTICALS INC014339105COM64,400$789,000thousands by filing date
Ocugen43358V109Common302,922$600,000thousands by filing date
SOPHIRIS BIO INC F83578Q209FOREIGN CANADIAN247,000$530,000thousands by filing date
Alcobra LtdM2239P109SHS272,788$276,000thousands by filing date
SOLENO THERAPEUTICS INC834203101COM84,748$220,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001306923-17-000025this filing2017-11-14acceptance time not in the bulk data set