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13F-HR filed by Palo Alto Investors LP

Palo Alto Investors LP filed this 13F-HR for the quarter ended 2015-06-30, filed 2015-08-14, with 45 holding rows worth $2,249,052,000.

Accession
0001306923-15-000019
Filed
2015-08-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q2 2015

A holdings report, 45 entries on the cover page, a total value of $2,249,052,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $2,249,052,000 with VALUE read as thousands by filing date, 13F file number 028-11013. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
UNITED THERAPEUTICS CORP DEL COM91307C102Stock1,439,928$250,475,000thousands by filing date
ANACOR PHARMACEUTICALS INC032420101COM3,103,027$240,267,000thousands by filing date
BIOMARIN PHARMACEUTICAL INC09061G101COM1,660,092$227,067,000thousands by filing date
CLOVIS ONCOLOGY INC189464100COM2,401,117$211,010,000thousands by filing date
ABIOMED INC003654100COM2,742,305$180,252,000thousands by filing date
AMAG PHARMACEUTICALS INC00163U106COM2,192,141$151,389,000thousands by filing date
INSMED INC COM PAR $.01457669307Stock4,733,601$115,595,000thousands by filing date
THORATEC CORP885175307COM2,560,303$114,113,000thousands by filing date
KYTHERA BIOPHARMACEUTICALS I501570105COM1,290,292$97,172,000thousands by filing date
ENDO INTL PLCG30401106SHS864,604$68,866,000thousands by filing date
WRIGHT MED GROUP INC98235T107COM2,056,251$53,997,000thousands by filing date
VANDA PHARMACEUTICALS INC921659108COM3,897,408$49,458,000thousands by filing date
KARYOPHARM THERAPEUTICS INC48576U106COM1,731,530$47,115,000thousands by filing date
PROTHENA CORP PLC SHSG72800108Stock695,918$36,654,000thousands by filing date
Gilead Sciences,Inc.375558103COM299,500$35,065,000thousands by filing date
MOMENTA PHARMACEUTICALS INC60877T100COM1,455,176$33,193,000thousands by filing date
SEQUENOM INC COM NEW817337405COM10,023,842$30,472,000thousands by filing date
CELGENE CORP151020104COM262,200$30,346,000thousands by filing date
AMICUS THERAPEUTICS INC03152W109COM1,974,376$27,937,000thousands by filing date
STAAR SURGICAL CO COM PAR $0.01852312305Stock2,642,922$25,531,000thousands by filing date
CYBERONICS23251P102COMMON STOCK412,000$24,498,000thousands by filing date
SHIRE PLC82481R106COMMON STOCK-FO98,300$23,738,000thousands by filing date
MEDIVATION INC58501N101COM180,300$20,590,000thousands by filing date
ARIAD PHARMACEUTICALS INC04033A100COM2,231,717$18,456,000thousands by filing date
HEARTWARE INTL INC422368100COM243,868$17,727,000thousands by filing date
ZELTIQ AESTHETICS INC98933Q108COM568,436$16,752,000thousands by filing date
RIGEL PHARMACEUTICALS INC766559603COMMON STOCK5,176,319$16,616,000thousands by filing date
Intuitive Surgical,Inc.46120E602COM32,350$15,674,000thousands by filing date
ALIMERA SCIENCES INC016259103COM3,013,793$13,894,000thousands by filing date
EXACT SCIENCES CORP COM30063P105Stock392,676$11,678,000thousands by filing date
OREXIGEN THERAPEUTICS INC686164104COMMON STOCK1,931,324$9,560,000thousands by filing date
ACELRX PHARMACEUTICALS INC00444T100COM2,135,739$9,056,000thousands by filing date
IDERA PHARMACEUTICALS INC45168K306COM1,226,748$4,551,000thousands by filing date
XOMA CORP DEL98419J107COM799,000$3,100,000thousands by filing date
Ocugen43358V109Common454,545$2,936,000thousands by filing date
SUNESIS PHARMACEUTICALS INC867328601COM NEW906,263$2,728,000thousands by filing date
BIOSPECIFICS TECHNOLOGIES090931106COM50,436$2,602,000thousands by filing date
INTREXON CORP46122T102COM47,100$2,298,000thousands by filing date
ALIGN TECHNOLOGY INC COM016255101Stock27,757$1,741,000thousands by filing date
EPIZYME INC29428V104COM61,265$1,470,000thousands by filing date
Alcobra LtdM2239P109SHS156,588$1,024,000thousands by filing date
DICERNA PHARMACEUTICALS INC253031108COM70,706$986,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW123,686$831,000thousands by filing date
Mallinckrodt PlcG5785G107SHS3,588$422,000thousands by filing date
SOPHIRIS BIO INC F83578Q209FOREIGN CANADIAN191,600$150,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001306923-15-000019this filing2015-08-14acceptance time not in the bulk data set