13F-HR filed by SPHERA FUNDS MANAGEMENT LTD.
SPHERA FUNDS MANAGEMENT LTD. filed this 13F-HR for the quarter ended 2020-09-30, filed 2020-11-12, with 96 holding rows worth $1,017,694,000.
- Accession
- 0001178913-20-003104
- Filer
- CIK 1496201
- Filed
- 2020-11-12
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q3 2020
A holdings report, 97 entries on the cover page, a total value of $1,017,694,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $1,017,696,000 with VALUE read as thousands by filing date, 13F file number 028-15863. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerSphera Global Healthcare GP Ltd.028-15864
- included managerSphera Global Healthcare Management LP028-15865
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| Merck & Co.,Inc. | 58933Y105 | COM | 883,808 | $73,312,000 | thousands by filing date | |
| AbbVie,Inc. | 00287Y109 | COM | 790,000 | $69,196,000 | thousands by filing date | |
| INVESCO QQQ TR | 46090E103 | COM | 210,000 | $58,346,000 | thousands by filing date | put |
| Johnson & Johnson | 478160104 | COM | 380,000 | $56,574,000 | thousands by filing date | |
| SANOFI SA SPONSORED ADR | 80105N105 | ADR | 1,120,000 | $56,190,000 | thousands by filing date | |
| ASTRAZENECA PLC SPONSORED ADR | 046353108 | ADR | 820,000 | $44,936,000 | thousands by filing date | |
| Eli Lilly and Company | 532457108 | COM | 200,000 | $29,604,000 | thousands by filing date | call |
| Amgen Inc. | 031162100 | COM | 110,000 | $27,958,000 | thousands by filing date | |
| NOVARTIS AG SPONSORED ADR | 66987V109 | ADR | 285,000 | $24,784,000 | thousands by filing date | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 171,500 | $24,084,000 | thousands by filing date | |
| Eli Lilly and Company | 532457108 | COM | 156,000 | $23,091,000 | thousands by filing date | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 150,000 | $21,064,000 | thousands by filing date | put |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 150,000 | $21,064,000 | thousands by filing date | call |
| DECIPHERA PHARMACEUTICALS IN | 24344T101 | COM | 343,965 | $17,645,000 | thousands by filing date | |
| AMICUS THERAPEUTICS INC | 03152W109 | COM | 1,243,550 | $17,559,000 | thousands by filing date | |
| Y-mAbs Therapeutics Inc | 984241109 | Common Stock | 396,521 | $15,222,000 | thousands by filing date | |
| TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS | 881624209 | ADR | 1,582,878 | $14,262,000 | thousands by filing date | |
| NICE LTD SPONSORED ADR | 653656108 | ADR | 62,481 | $14,185,000 | thousands by filing date | |
| GENERAC HLDGS INC | 368736104 | COM | 67,000 | $12,974,000 | thousands by filing date | |
| ISHARES RUSSELL MID-CAP GROWTH ETF | 464287481 | ETF | 73,500 | $12,706,000 | thousands by filing date | put |
| Amazon.com, Inc | 023135106 | COM | 3,820 | $12,028,000 | thousands by filing date | |
| BIOXCEL THERAPEUTICS INC | 09075P105 | COM | 269,300 | $11,677,000 | thousands by filing date | |
| MYOKARDIA INC | 62857M105 | COM | 81,000 | $11,043,000 | thousands by filing date | |
| KURA ONCOLOGY INC COM | 50127T109 | Stock | 359,494 | $11,015,000 | thousands by filing date | |
| AbbVie,Inc. | 00287Y109 | COM | 125,000 | $10,949,000 | thousands by filing date | call |
| Microsoft Corp | 594918104 | COM | 51,278 | $10,785,000 | thousands by filing date | |
| ALLOT LTD | M0854Q105 | SHS | 1,045,337 | $9,513,000 | thousands by filing date | |
| KORNIT DIGITAL LTD | M6372Q113 | SHS | 143,381 | $9,301,000 | thousands by filing date | |
| TRILLIUM THERAPEUTICS INC COM NEW | 89620X506 | Stock | 645,435 | $9,172,000 | thousands by filing date | |
| META PLATFORMS INC CL A | 30303M102 | COM | 35,000 | $9,167,000 | thousands by filing date | |
| NOVABRIDGE BIOSCIENCES | 44975P103 | CMN | 181,820 | $8,551,000 | thousands by filing date | |
| IMMATICS N.V | N44445109 | SHS | 800,000 | $8,488,000 | thousands by filing date | |
| IOVANCE BIOTHERAPEUTICS INC | 462260100 | COM | 253,000 | $8,329,000 | thousands by filing date | |
| JFROG LTD ORD SHS | M6191J100 | Stock | 95,415 | $8,077,000 | thousands by filing date | |
| FIVERR INTL LTD ORD SHS | M4R82T106 | Stock | 57,301 | $7,964,000 | thousands by filing date | |
| KRYSTAL BIOTECH INC COM | 501147102 | Stock | 184,573 | $7,946,000 | thousands by filing date | |
| WAVE LIFE SCIENCES LTD SHS | Y95308105 | Stock | 931,200 | $7,906,000 | thousands by filing date | |
| REPARE THERAPEUTICS INC | 760273102 | COM | 245,000 | $7,539,000 | thousands by filing date | |
| SYNDAX PHARMACEUTICALS INC | 87164F105 | COM | 510,000 | $7,528,000 | thousands by filing date | |
| FATE THERAPEUTICS INC | 31189P102 | COM | 188,000 | $7,514,000 | thousands by filing date | |
| FISERV INC | 337738108 | COM | 70,246 | $7,239,000 | thousands by filing date | |
| BURLINGTON STORES INC COM | 122017106 | Stock | 35,000 | $7,213,000 | thousands by filing date | |
| VARONIS SYS INC | 922280102 | COM | 60,225 | $6,951,000 | thousands by filing date | |
| DOMINOS PIZZA INC COM | 25754A201 | Stock | 16,221 | $6,898,000 | thousands by filing date | |
| ALX ONCOLOGY HOLDINGS INC | 00166B105 | COMMON STOCK | 182,070 | $6,871,000 | thousands by filing date | |
| ZENTALIS PHARMACEUTICALS INC | 98943L107 | COMMON STOCK | 194,996 | $6,374,000 | thousands by filing date | |
| VERONA PHARMA PLC | 925050106 | SPONSORED ADS | 1,000,000 | $6,240,000 | thousands by filing date | |
| ITEOS THERAPEUTICS INC | 46565G104 | COM | 250,000 | $6,168,000 | thousands by filing date | |
| IMMUNOVANT INC | 45258J102 | COM | 170,000 | $5,982,000 | thousands by filing date | |
| ALBIREO PHARMA INC | 01345P106 | COMMON STOCK | 173,600 | $5,793,000 | thousands by filing date | |
| REATA PHARMACEUTICALS INC | 75615P103 | CL A | 59,139 | $5,761,000 | thousands by filing date | |
| ARENA PHARMACEUTICALS INC | 040047607 | COM NEW | 75,000 | $5,609,000 | thousands by filing date | |
| ARYA SCIENCES ACQUISTION CO | G31655114 | UNIT 06/09/2027 | 499,000 | $5,489,000 | thousands by filing date | |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 370,000 | $5,487,000 | thousands by filing date | |
| MIRATI THERAPEUTICS INC | 60468T105 | COM | 33,000 | $5,480,000 | thousands by filing date | |
| AXOVANT SCIENCES LTD | G0750W203 | COM | 1,152,998 | $5,327,000 | thousands by filing date | |
| ROCKET PHARMACEUTICALS INC | 77313F106 | COM | 228,016 | $5,212,000 | thousands by filing date | |
| LARIMAR THERAPEUTICS INC | 517125100 | COM | 342,064 | $5,189,000 | thousands by filing date | |
| KYMERA THERAPEUTICS INC | 501575104 | COM | 160,000 | $5,170,000 | thousands by filing date | |
| INOZYME PHARMA INC | 45790W108 | COM | 196,411 | $5,164,000 | thousands by filing date | |
| ASCENDIS PHARMA A/S DKK 1.0 AD | 04351P101 | SPONSORED ADR | 32,599 | $5,031,000 | thousands by filing date | |
| UNIQURE NV | N90064101 | SHS | 126,000 | $4,641,000 | thousands by filing date | |
| ARYA SCIENCES ACQUISITION CO | G3166W106 | COM CL A | 400,000 | $4,288,000 | thousands by filing date | |
| GALERA THERAPEUTICS EQUICLASS EQUITY | 36338D108 | COMMON STOCK | 469,245 | $4,242,000 | thousands by filing date | |
| TECTONIC THERAPEUTIC INC COM | 05455M100 | Stock | 325,500 | $4,238,000 | thousands by filing date | |
| KINIKSA PHARMACEUTICALS LTD | G5269C101 | COM CL A | 259,990 | $3,983,000 | thousands by filing date | |
| ZYMEWORKS INC | 98985W102 | COM | 80,000 | $3,726,000 | thousands by filing date | |
| DICERNA PHARMACEUTICALS INC | 253031108 | COM | 199,980 | $3,598,000 | thousands by filing date | |
| PASSAGE BIO INC | 702712100 | COM | 266,037 | $3,488,000 | thousands by filing date | |
| PERRIGO CO PLC SHS | G97822103 | Stock | 71,559 | $3,285,000 | thousands by filing date | |
| ALTIMMUNE INC | 02155H200 | COM NEW | 243,000 | $3,208,000 | thousands by filing date | |
| ARVINAS INC | 04335A105 | COM | 135,000 | $3,187,000 | thousands by filing date | |
| CONCERT PHARMACEUTICALS INC | 206022105 | COM | 310,000 | $3,044,000 | thousands by filing date | |
| KALVISTA PHARMACEUTICALS INC | 483497103 | COM | 240,140 | $3,023,000 | thousands by filing date | |
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 10,265 | $2,695,000 | thousands by filing date | |
| ADMA BIOLOGICS INC | 000899104 | COM | 1,081,292 | $2,584,000 | thousands by filing date | |
| ATHIRA PHARMA INC | 04746L104 | COM | 112,000 | $2,068,000 | thousands by filing date | |
| ORGENESIS INC | 68619K204 | COM | 398,803 | $2,010,000 | thousands by filing date | |
| ALPINE IMMUNE SCIENCES INC | 02083G100 | COM | 198,260 | $1,743,000 | thousands by filing date | |
| ESSA PHARMA INC | 29668H708 | COM NEW | 250,000 | $1,725,000 | thousands by filing date | |
| LEAP THERAPEUTICS INC | 52187K101 | COM | 800,000 | $1,584,000 | thousands by filing date | |
| 89BIO INC | 282559103 | COM | 58,939 | $1,512,000 | thousands by filing date | |
| DYNE THERAPEUTICS INC COM | 26818M108 | Stock | 70,000 | $1,413,000 | thousands by filing date | |
| EXICURE INC | 30205M101 | COM | 737,557 | $1,291,000 | thousands by filing date | |
| Ohr Pharmaceutical Inc | 64132K102 | COM | 150,000 | $1,139,000 | thousands by filing date | |
| HEALTH SCIENCES ACQ CORP 2 | G4411D109 | ORD SHS | 100,000 | $1,100,000 | thousands by filing date | |
| PANDION THERAPEUTICS INC | 698340106 | COM | 95,000 | $1,089,000 | thousands by filing date | |
| SOLAREDGE TECHNOLOGIES INC | 83417M104 | COM | 4,017 | $957,000 | thousands by filing date | |
| NURIX THERAPEUTICS INC | 67080M103 | COMMON STOCK | 22,480 | $785,000 | thousands by filing date | |
| NICE SYS INC | 65366HAB9 | BOND | 250,000 | $681,000 | thousands by filing date | |
| CARDIFF ONCOLOGY INC | 14147L108 | COM | 40,000 | $568,000 | thousands by filing date | |
| IMMATICS N.V | N44445117 | *W EXP 07/01/202 | 100,000 | $350,000 | thousands by filing date | |
| THERAPEUTICS ACQUISITION COR | 88339T103 | COM CL A | 20,000 | $288,000 | thousands by filing date | |
| CORBUS PHARMACEUTICALS HLDGS | 21833P103 | COM | 78,500 | $141,000 | thousands by filing date | call |
| CELLECTAR BIOSCIENCES INC | 15117F500 | COM PAR | 87,500 | $109,000 | thousands by filing date | |
| OUTLOOK THERAPEUTICS INC | 69012T115 | *W EXP 02/18/202 | 129,500 | $17,000 | thousands by filing date |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001178913-20-003104 | this filing | 2020-11-12 | acceptance time not in the bulk data set |