13F-HR filed by SPHERA FUNDS MANAGEMENT LTD.
SPHERA FUNDS MANAGEMENT LTD. filed this 13F-HR for the quarter ended 2020-03-31, filed 2020-05-14, with 78 holding rows worth $799,546,000.
- Accession
- 0001178913-20-001462
- Filer
- CIK 1496201
- Filed
- 2020-05-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q1 2020
A holdings report, 78 entries on the cover page, a total value of $799,546,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $799,546,000 with VALUE read as thousands by filing date, 13F file number 028-15863. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerSphera Global Healthcare GP Ltd.028-15864
- included managerSphera Global Healthcare Management LP028-15865
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| iShares Russell 2000 ETF | 464287655 | SHS | 900,000 | $103,014,000 | thousands by filing date | put |
| Merck & Co.,Inc. | 58933Y105 | COM | 868,518 | $66,824,000 | thousands by filing date | |
| SPY | 78462F103 | SHS | 209,900 | $54,102,000 | thousands by filing date | put |
| Johnson & Johnson | 478160104 | COM | 348,653 | $45,719,000 | thousands by filing date | |
| Bristol-Myers Squibb Company | 110122108 | COM | 780,000 | $43,477,000 | thousands by filing date | |
| SANOFI SA SPONSORED ADR | 80105N105 | ADR | 970,000 | $42,408,000 | thousands by filing date | |
| SPDR SER TR | 78464A870 | S&P BIOTECH | 500,000 | $38,720,000 | thousands by filing date | put |
| NOVO-NORDISK A S ADR | 670100205 | ADR | 576,000 | $34,675,000 | thousands by filing date | |
| ASTRAZENECA PLC SPONSORED ADR | 046353108 | ADR | 570,000 | $25,456,000 | thousands by filing date | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 258,000 | $25,238,000 | thousands by filing date | |
| ALEXION PHARMACEUTICALS INC | 015351109 | COM | 249,396 | $22,393,000 | thousands by filing date | |
| AMICUS THERAPEUTICS INC | 03152W109 | COM | 2,017,624 | $18,643,000 | thousands by filing date | |
| Pfizer Inc. | 717081103 | COM | 550,000 | $17,952,000 | thousands by filing date | |
| Microsoft Corp | 594918104 | COM | 93,964 | $14,819,000 | thousands by filing date | |
| AbbVie,Inc. | 00287Y109 | COM | 165,000 | $12,571,000 | thousands by filing date | |
| NOVARTIS AG SPONSORED ADR | 66987V109 | ADR | 140,000 | $11,543,000 | thousands by filing date | |
| KARYOPHARM THERAPEUTICS INC | 48576U106 | COM | 550,000 | $10,566,000 | thousands by filing date | |
| Amazon.com, Inc | 023135106 | COM | 5,270 | $10,275,000 | thousands by filing date | |
| UNIQURE NV | N90064101 | SHS | 201,107 | $9,543,000 | thousands by filing date | |
| CONCERT PHARMACEUTICALS INC | 206022105 | COM | 1,013,039 | $8,955,000 | thousands by filing date | |
| X4 Pharmaceuticals, Inc. | 98420X103 | COM | 873,215 | $8,732,000 | thousands by filing date | |
| ALLOT LTD | M0854Q105 | SHS | 915,302 | $8,650,000 | thousands by filing date | |
| Y-mAbs Therapeutics Inc | 984241109 | Common Stock | 307,379 | $8,023,000 | thousands by filing date | |
| SELECT SECTOR SPDR TR | 81369Y308 | STATE STREET CON | 145,207 | $7,909,000 | thousands by filing date | |
| ZYMEWORKS INC | 98985W102 | COM | 206,830 | $7,336,000 | thousands by filing date | |
| AXOVANT SCIENCES LTD | G0750W203 | COM | 2,931,018 | $7,152,000 | thousands by filing date | |
| PASSAGE BIO INC | 702712100 | COM | 478,171 | $7,135,000 | thousands by filing date | |
| ACADIA PHARMACEUTICALS INC | 004225108 | COM | 157,000 | $6,633,000 | thousands by filing date | |
| BLUEPRINT MEDICINES CORP | 09627Y109 | COM | 109,500 | $6,404,000 | thousands by filing date | |
| ARVINAS INC | 04335A105 | COM | 145,781 | $5,875,000 | thousands by filing date | |
| ADMA BIOLOGICS INC | 000899104 | COM | 1,838,100 | $5,294,000 | thousands by filing date | |
| Salesforce.com, Inc | 79466L302 | COM | 35,529 | $5,115,000 | thousands by filing date | |
| TRILLIUM THERAPEUTICS INC COM NEW | 89620X506 | Stock | 1,260,694 | $5,093,000 | thousands by filing date | |
| AUDIOCODES LTD | M15342104 | ORD | 206,619 | $4,936,000 | thousands by filing date | |
| DECIPHERA PHARMACEUTICALS IN | 24344T101 | COM | 119,500 | $4,920,000 | thousands by filing date | |
| EXICURE INC | 30205M101 | COM | 3,284,795 | $4,861,000 | thousands by filing date | |
| BEAM THERAPEUTICS INC | 07373V105 | COM | 264,681 | $4,764,000 | thousands by filing date | |
| ROCKET PHARMACEUTICALS INC | 77313F106 | COM | 335,016 | $4,673,000 | thousands by filing date | |
| GALERA THERAPEUTICS EQUICLASS EQUITY | 36338D108 | COMMON STOCK | 475,677 | $4,519,000 | thousands by filing date | |
| NEOLEUKIN THERAPEUTICS INC | 64049K104 | COM | 397,000 | $4,518,000 | thousands by filing date | |
| ORGENESIS INC | 68619K204 | COM | 1,109,564 | $4,216,000 | thousands by filing date | |
| PROTAGONIST THERAPEUTICS | 74366E102 | COM | 526,075 | $3,714,000 | thousands by filing date | |
| ASCENDIS PHARMA A/S DKK 1.0 AD | 04351P101 | SPONSORED ADR | 32,573 | $3,668,000 | thousands by filing date | |
| TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS | 881624209 | ADR | 356,713 | $3,203,000 | thousands by filing date | |
| PROTEOSTASIS THERAPEUTICS IN | 74373B109 | COM | 2,536,600 | $2,892,000 | thousands by filing date | |
| VIKING THERAPEUTICS INC | 92686J106 | COM | 590,000 | $2,761,000 | thousands by filing date | |
| PALO ALTO NETWORKS INC | 697435105 | COM | 16,452 | $2,697,000 | thousands by filing date | |
| ALDEYRA THERAPEUTICS INC | 01438T106 | COM | 1,069,089 | $2,641,000 | thousands by filing date | |
| FIVERR INTL LTD ORD SHS | M4R82T106 | Stock | 104,839 | $2,639,000 | thousands by filing date | |
| FILANA THERAPEUTICS INC | 14817C107 | CMN | 615,000 | $2,528,000 | thousands by filing date | |
| ZAFGEN INC | 98885E103 | COM | 3,161,562 | $2,434,000 | thousands by filing date | |
| EVOLUS INC | 30052C107 | COM | 550,000 | $2,283,000 | thousands by filing date | |
| ARYA SCIENCES ACQUISITION CO | G3165V117 | UNIT 10/04/2023 | 200,000 | $2,258,000 | thousands by filing date | |
| Applied Therapeutics Inc | 03828A101 | Common Stock | 67,967 | $2,222,000 | thousands by filing date | |
| PROQR THERAPEUTICS NV | N71542109 | SHS EURO | 346,148 | $1,900,000 | thousands by filing date | |
| NEOS THERAPEUTICS INC | 64052L106 | COM | 2,509,468 | $1,882,000 | thousands by filing date | |
| KALVISTA PHARMACEUTICALS INC | 483497103 | COM | 240,140 | $1,837,000 | thousands by filing date | |
| Vertex Pharmaceuticals Incorporated | 92532F100 | COM | 7,000 | $1,666,000 | thousands by filing date | |
| IMMUNOVANT INC | 45258J201 | UNIT 12/18/2024 | 94,500 | $1,564,000 | thousands by filing date | |
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 10,265 | $1,352,000 | thousands by filing date | |
| GLOBAL BLOOD THERAPEUTICS USD | 37890U108 | COM | 24,752 | $1,265,000 | thousands by filing date | |
| MINERVA NEUROSCIENCES INC COM NEW | 603380106 | Stock | 168,357 | $1,014,000 | thousands by filing date | |
| LEAP THERAPEUTICS INC | 52187K101 | COM | 600,000 | $948,000 | thousands by filing date | |
| PRECISION BIOSCIENCES INC | 74019P108 | COM | 147,352 | $889,000 | thousands by filing date | |
| APTINYX INC | 03836N103 | COM | 411,666 | $889,000 | thousands by filing date | |
| SYNDAX PHARMACEUTICALS INC | 87164F105 | COM | 68,134 | $747,000 | thousands by filing date | |
| Allena Pharmaceuticals, Inc. | 018119107 | COM | 667,800 | $643,000 | thousands by filing date | |
| STOKE THERAPEUTICS INC | 86150R107 | COM | 27,254 | $624,000 | thousands by filing date | |
| NICE SYS INC | 65366HAB9 | BOND | 250,000 | $445,000 | thousands by filing date | |
| IVERIC BIO INC | 46583P102 | COM | 123,424 | $425,000 | thousands by filing date | |
| ZYNERBA PHARMACEUTICALS INC | 98986X109 | COM | 100,000 | $383,000 | thousands by filing date | |
| CYCLERION THERAPEUTICS INC | 23255M105 | COM | 124,976 | $331,000 | thousands by filing date | |
| SUNESIS PHARMACEUTICALS INC | 867328700 | COM | 721,800 | $299,000 | thousands by filing date | |
| IMMUNOVANT INC | 45258J102 | COM | 19,032 | $296,000 | thousands by filing date | |
| BRISTOL-MYERS SQUIBB CO | 110122157 | RIGHT 99/99/9999 | 50,000 | $190,000 | thousands by filing date | |
| OUTLOOK THERAPEUTICS INC | 69012T115 | *W EXP 02/18/202 | 129,500 | $130,000 | thousands by filing date | |
| Milestone Pharmaceuticals Inc | 59935V107 | COM | 67,992 | $125,000 | thousands by filing date | |
| CELLECTAR BIOSCIENCES INC | 15117F500 | COM PAR | 87,500 | $111,000 | thousands by filing date |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001178913-20-001462 | this filing | 2020-05-14 | acceptance time not in the bulk data set |