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13F-HR filed by SPHERA FUNDS MANAGEMENT LTD.

SPHERA FUNDS MANAGEMENT LTD. filed this 13F-HR for the quarter ended 2017-06-30, filed 2017-08-09, with 128 holding rows worth $588,587,000 by the sum of the rows.

Accession
0001178913-17-002344
Filed
2017-08-09
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q2 2017

A holdings report, 128 entries on the cover page, a total value of $558,578,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $588,587,000 with VALUE read as thousands by filing date, 13F file number 028-15863. The quarter's positions are built on this report. The resolved quarter.

The cover page states a total of $558,578,000, 5% less than the sum of the rows, $588,587,000. This page uses the sum of the rows.

Other managers

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
SPDR SERIES TRUST78464A950PUT5,566$43,509,000thousands by filing dateput
CELGENE CORP151020104COM250,000$32,468,000thousands by filing date
BIOGEN INC COM09062X103Stock90,000$24,422,000thousands by filing date
Merck & Co.,Inc.58933Y105COM320,000$20,509,000thousands by filing date
GLAXOSMITHKLINE PLC-ADR37733W105SPONSORED ADR450,000$19,404,000thousands by filing date
POWERSHARES QQQ NASDAQ 10073935A954COM1,200$17,188,000thousands by filing dateput
Gilead Sciences,Inc.375558103COM230,000$16,279,000thousands by filing date
NOVARTIS AG SPONSORED ADR66987V109ADR200,000$15,960,000thousands by filing date
BIOGEN INC09062X903CALL500$14,480,000thousands by filing datecall
Bristol-Myers Squibb Company110122108COM248,000$13,819,000thousands by filing date
Pfizer Inc.717081103COM390,000$13,100,000thousands by filing date
SAREPTA THERAPEUTICS INC803607100COM383,047$12,913,000thousands by filing date
ALEXION PHARMACEUTICALS INC015351109COM100,000$12,167,000thousands by filing date
SHIRE PLC82481R106COMMON STOCK-FO68,500$11,321,000thousands by filing date
ITURAN LOCATION AND CONTROL SHSM6158M104Stock304,421$9,528,000thousands by filing date
CLOVIS ONCOLOGY INC189464100COM93,000$8,708,000thousands by filing date
TEVA PHARMACEUTICAL FIN LLC88163VAE9DBCV 0.250% 2/014,535$8,641,000thousands by filing date
TESARO INC881569107COM55,000$7,692,000thousands by filing date
ORBOTECH LTDM75253100ORD213,740$6,972,000thousands by filing date
BIOMARIN PHARMACEUTICAL INC09061G101COM75,000$6,812,000thousands by filing date
CELGENE CORP151020904COM500$6,771,000thousands by filing datecall
NICE LTD SPONSORED ADR653656108ADR85,052$6,695,000thousands by filing date
VERSARTIS INC92529L102COM377,524$6,588,000thousands by filing date
ARRAY BIOPHARMA INC COM04269X105Stock700,000$5,859,000thousands by filing date
MYLAN N VN59465909CALL1,500$5,849,000thousands by filing datecall
PIERIS PHARMACEUTICALS INC720795103COM1,100,000$5,566,000thousands by filing date
FIBROGEN INC31572Q808COM165,700$5,352,000thousands by filing date
CELLECTIS ADS15117K103COM203,764$5,261,000thousands by filing date
Visa Inc92826C839COM52,951$4,966,000thousands by filing date
AVEO PHARMACEUTICALS INC053588109COM2,200,000$4,884,000thousands by filing date
META PLATFORMS INC CL A30303M102COM32,167$4,857,000thousands by filing date
IMMUNOMEDICS INC452907108COM550,000$4,857,000thousands by filing date
Union Pacific Corporation907818108COM42,400$4,618,000thousands by filing date
SELECTA BIOSCIENCES INC816212104COM228,534$4,539,000thousands by filing date
CHARTER COMMUNICATIONS INC N16119P108COM13,362$4,501,000thousands by filing date
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR161,617$4,486,000thousands by filing date
CAESARSTONE LTDM20598104ORD SHS122,797$4,304,000thousands by filing date
MINERVA NEUROSCIENCES INC COM NEW603380106Stock473,769$4,193,000thousands by filing date
IGNYTA INC451731103COM400,000$4,140,000thousands by filing date
SYNDAX PHARMACEUTICALS INC87164F105COM296,310$4,139,000thousands by filing date
ALDEYRA THERAPEUTICS INC01438T106COM875,931$4,117,000thousands by filing date
GLOBAL BLOOD THERAPEUTICS USD37890U108COM150,000$4,103,000thousands by filing date
RETROPHIN INC761299106COM209,131$4,055,000thousands by filing date
Alphabet Inc. Reg. Shares A02079K305COM4,346$4,040,000thousands by filing date
AMICUS THERAPEUTICS INC03152W109COM400,000$4,028,000thousands by filing date
ALNYLAM PHARMACEUTICALS INC COM02043Q107Stock50,000$3,988,000thousands by filing date
NOMAD FOODS LTD USD ORD SHSG6564A105Stock268,072$3,782,000thousands by filing date
LA JOLLA PHARMACEUTICAL CO503459604COM PAR $.0001 2125,000$3,721,000thousands by filing date
INTERCEPT PHARMACEUTICALS IN45845P108COM30,000$3,632,000thousands by filing date
TEVA PHARMACEUTICAL INDS LTD881624959PUT1,120$3,603,000thousands by filing dateput
GLYCOMIMETICS INC38000Q102COM320,796$3,580,000thousands by filing date
SOLAREDGE TECHNOLOGIES INC83417M104COM171,018$3,420,000thousands by filing date
ADAMAS PHARMACEUTICALS INC00548A106COM195,500$3,419,000thousands by filing date
DBV TECHNOLOGIES S A23306J101ADR90,167$3,220,000thousands by filing date
CORVUS PHARMACEUTICALS INC221015100COM257,665$3,118,000thousands by filing date
CYTOMX THERAPEUTICS INC23284F105COMMON STOCK200,000$3,100,000thousands by filing date
SAVARA INC805111101COM526,315$3,095,000thousands by filing date
THERAPEUTICSMD INC88338N107COM580,000$3,057,000thousands by filing date
EIGER BIOPHARMACEUTICALS INC28249U105COM385,301$3,044,000thousands by filing date
OVID THERAPEUTICS INC690469101COMMON STOCK305,674$3,042,000thousands by filing date
BELLICUM PHARMACEUTICALS INC079481107COM250,000$2,920,000thousands by filing date
AUDENTES THERAPEUTICS INC.05070R104Common Stock150,000$2,870,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM62,000$2,852,000thousands by filing date
ADVANCE AUTO PARTS INC00751Y906COM NEW250$2,800,000thousands by filing datecall
STEMLINE THERAPEUTICS INC85858C107COM300,000$2,760,000thousands by filing date
BRAINSTORM CELL THERAPEUTICS10501E201COM833,633$2,759,000thousands by filing date
AXSOME THERAPEUTICS INC. COM05464T104Stock501,000$2,756,000thousands by filing date
CLEARSIDE BIOMEDICAL INC185063104COM300,000$2,733,000thousands by filing date
ENDO INTL PLCG30401106SHS240,000$2,681,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW217,990$2,638,000thousands by filing date
GENOCEA BIOSCIENCES INC372427104COM490,000$2,558,000thousands by filing date
CASCADIAN THERAPEUTICS INC14740B606COM NEW681,210$2,531,000thousands by filing date
SNAP ON INC COM833034101Stock15,797$2,496,000thousands by filing date
LAM RESEARCH CORP512807108COM16,860$2,385,000thousands by filing date
SPRING BK PHARMACEUTICALS IN849431101COM175,000$2,370,000thousands by filing date
Oracle Corporation68389X105COM47,250$2,369,000thousands by filing date
PORTOLA PHARMACEUTICALS INC COM737010108Stock40,000$2,247,000thousands by filing date
NEURODERM LTDM74231107ORD SHS74,500$2,228,000thousands by filing date
PROTHENA CORP PLC SHSG72800108Stock40,000$2,165,000thousands by filing date
ALBIREO PHARMA INC01345P106COMMON STOCK103,526$2,133,000thousands by filing date
DOVA PHARMACEUTICALS INC25985T102COM95,000$2,118,000thousands by filing date
OREILLY AUTOMOTIVE INC67103H907CALL100$2,043,000thousands by filing datecall
Thermo Fisher Scientific Inc.883556102COM11,688$2,039,000thousands by filing date
ObsEva SAH5861P103COM231,497$1,979,000thousands by filing date
SEATTLE GENETICS INC812578102COM36,000$1,863,000thousands by filing date
MARINUS PHARMACEUTICALS INC56854Q101COM1,331,421$1,824,000thousands by filing date
TJX Companies Inc872540109COM24,700$1,783,000thousands by filing date
ARDELYX INC039697107COM345,000$1,760,000thousands by filing date
PROQR THERAPEUTICS NVN71542109SHS EURO330,000$1,716,000thousands by filing date
SAPIENS INTERNATIONAL CORPN7716A151SHS147,306$1,648,000thousands by filing date
ACHAOGEN INC004449104COM75,000$1,630,000thousands by filing date
TOWER SEMICONDUCTOR LTD SHS NEWM87915274Stock67,155$1,602,000thousands by filing date
SUMMIT THERAPEUTICS INC COM86627R102Stock142,018$1,561,000thousands by filing date
FLEX LTD ORDY2573F102Stock94,500$1,541,000thousands by filing date
EDGE THERAPEUTICS INC279870109COM150,000$1,539,000thousands by filing date
WABTEC COM929740108Stock16,600$1,519,000thousands by filing date
VTV THERAPEUTICS INC CL A918385105Stock300,000$1,491,000thousands by filing date
MACROGENICS INC556099109COM81,200$1,422,000thousands by filing date
ISHARES TR464287905CALL100$1,415,000thousands by filing datecall
MasterCard, Inc57636Q104COM11,525$1,400,000thousands by filing date
AILERON THERAPEUTICS INC COM NEW00887A105Stock125,000$1,394,000thousands by filing date
EVOKE PHARMA INC30049G104COM500,000$1,280,000thousands by filing date
KORNIT DIGITAL LTDM6372Q113SHS57,300$1,109,000thousands by filing date
ACCELERON PHARMA INC00434H108COM35,000$1,064,000thousands by filing date
VISTAGEN THERAPEUTICS INC92840H202COM544,100$1,017,000thousands by filing date
AQUINOX PHARMACEUTICALS INC03842B101COM62,085$874,000thousands by filing date
VERISK ANALYTICS INC COM92345Y106Stock9,400$793,000thousands by filing date
Rocket Pharmaceuticals Inc45780V102SHS401,764$763,000thousands by filing date
XENON PHARMACEUTICALS INC COM98420N105Stock228,029$718,000thousands by filing date
SUNESIS PHARMACEUTICALS INC867328700COM193,212$522,000thousands by filing date
CAMTEK LTD ORDM20791105Stock99,035$478,000thousands by filing date
CATABASIS PHARMACEUTICALS IN14875P107COM288,030$409,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM5,000$398,000thousands by filing date
UnitedHealth Group Inc91324P102COM2,000$371,000thousands by filing date
WATSCO INC COM942622200Stock2,100$324,000thousands by filing date
NOVA LTD COMM7516K103Stock13,844$306,000thousands by filing date
MOHAWK INDS INC608190104COM1,100$266,000thousands by filing date
PALATIN TECHNOLOGIES INC696077403COM PAR $ .01470,983$203,000thousands by filing date
Lowes Companies,Inc.548661107COM2,600$202,000thousands by filing date
SEALED AIR CORP NEW81211K100COM4,500$201,000thousands by filing date
SERVICEMASTER GLOBAL HOLDING81761R109COMMON STOCK5,000$196,000thousands by filing date
THE ULTIMATE SOFTWARE GROUP IN90385D107COM800$168,000thousands by filing date
CHIPOTLEMEXICANGRILLI169656105STOK400$166,000thousands by filing date
DENTSPLY SIRONA INC24906P109COM2,500$162,000thousands by filing date
LIBERTY INTERACTIVE CORP53071M856LBT VEN COM A NE3,000$157,000thousands by filing date
TRIPADVISOR INC896945201COM4,000$153,000thousands by filing date
VISTA OUTDOOR INC928377100COM6,000$135,000thousands by filing date
ECOLAB INC COM278865100Stock1,000$133,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001178913-17-002344this filing2017-08-09acceptance time not in the bulk data set