13F-HR filed by SPHERA FUNDS MANAGEMENT LTD.
SPHERA FUNDS MANAGEMENT LTD. filed this 13F-HR for the quarter ended 2016-12-31, filed 2017-02-13, with 104 holding rows worth $395,050,000.
- Accession
- 0001178913-17-000411
- Filer
- CIK 1496201
- Filed
- 2017-02-13
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2016
A holdings report, 104 entries on the cover page, a total value of $395,050,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $395,050,000 with VALUE read as thousands by filing date, 13F file number 028-15863. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerSphera Global Healthcare GP Ltd.028-15864
- included managerSphera Global Healthcare Management LP028-15865
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| SPDR SERIES TRUST | 78464A950 | PUT | 550,000 | $32,555,000 | thousands by filing date | put |
| Merck & Co.,Inc. | 58933Y105 | COM | 450,000 | $26,492,000 | thousands by filing date | |
| CELGENE CORP | 151020104 | COM | 180,000 | $20,835,000 | thousands by filing date | |
| TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS | 881624209 | ADR | 522,000 | $18,923,000 | thousands by filing date | |
| ALEXION PHARMACEUTICALS INC | 015351109 | COM | 113,000 | $13,826,000 | thousands by filing date | |
| ISHARES TR | 464287955 | PUT | 100,000 | $13,485,000 | thousands by filing date | put |
| ISHARES TR | 464287903 | CALL | 100,000 | $13,485,000 | thousands by filing date | call |
| COLUCID PHARMACEUTICALS INC | 19716T101 | COM | 358,000 | $13,031,000 | thousands by filing date | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 398,047 | $10,918,000 | thousands by filing date | |
| ITURAN LOCATION AND CONTROL SHS | M6158M104 | Stock | 306,633 | $8,126,000 | thousands by filing date | |
| ARRAY BIOPHARMA INC COM | 04269X105 | Stock | 900,000 | $7,911,000 | thousands by filing date | |
| TEVA PHARMACEUTICAL INDS LTD | 881624909 | CALL | 215,000 | $7,794,000 | thousands by filing date | call |
| ACHAOGEN INC | 004449104 | COM | 514,342 | $6,697,000 | thousands by filing date | |
| ASCENDIS PHARMA A/S DKK 1.0 AD | 04351P101 | SPONSORED ADR | 326,622 | $6,611,000 | thousands by filing date | |
| SHIRE PLC | 82481R106 | COMMON STOCK-FO | 32,500 | $5,537,000 | thousands by filing date | |
| HORIZON PHARMA PLC | G4617B105 | SHS | 300,000 | $4,854,000 | thousands by filing date | |
| CHARTER COMMUNICATIONS INC N | 16119P108 | COM | 16,165 | $4,654,000 | thousands by filing date | |
| SELECTA BIOSCIENCES INC | 816212104 | COM | 268,534 | $4,605,000 | thousands by filing date | |
| SAGE THERAPEUTICS INC | 78667J108 | COM | 90,000 | $4,595,000 | thousands by filing date | |
| CORVUS PHARMACEUTICALS INC | 221015100 | COM | 320,229 | $4,579,000 | thousands by filing date | |
| ADAMAS PHARMACEUTICALS INC | 00548A106 | COM | 270,000 | $4,563,000 | thousands by filing date | |
| Alphabet Inc. Reg. Shares A | 02079K305 | COM | 5,748 | $4,555,000 | thousands by filing date | |
| GLYCOMIMETICS INC | 38000Q102 | COM | 745,796 | $4,549,000 | thousands by filing date | |
| EIGER BIOPHARMACEUTICALS INC | 28249U105 | COM | 385,301 | $4,489,000 | thousands by filing date | |
| TEVA PHARMACEUTICAL FIN LLC | 88163VAE9 | DBCV 0.250% 2/0 | 6,585 | $4,247,000 | thousands by filing date | |
| Visa Inc | 92826C839 | COM | 51,951 | $4,053,000 | thousands by filing date | |
| NEURODERM LTD | M74231107 | ORD SHS | 175,951 | $3,906,000 | thousands by filing date | |
| IMMUNOMEDICS INC | 452907108 | COM | 1,050,000 | $3,854,000 | thousands by filing date | |
| FOAMIX PHARMACEUTICALS LTD | M46135105 | SHS | 342,000 | $3,796,000 | thousands by filing date | |
| Union Pacific Corporation | 907818108 | COM | 36,076 | $3,740,000 | thousands by filing date | |
| BIOMARIN PHARMACEUTICAL INC | 09061G101 | COM | 45,000 | $3,728,000 | thousands by filing date | |
| VERSARTIS INC | 92529L102 | COM | 250,000 | $3,725,000 | thousands by filing date | |
| AMICUS THERAPEUTICS INC | 03152W109 | COM | 730,000 | $3,628,000 | thousands by filing date | |
| FIBROGEN INC | 31572Q808 | COM | 155,700 | $3,332,000 | thousands by filing date | |
| Vertex Pharmaceuticals Incorporated | 92532F100 | COM | 45,000 | $3,315,000 | thousands by filing date | |
| FIDELITY NATL INFORMATION SVCS COM | 31620M106 | Stock | 43,503 | $3,291,000 | thousands by filing date | |
| AIR PRODS & CHEMS INC | 009158106 | COM | 21,165 | $3,044,000 | thousands by filing date | |
| Schlumberger Limited | 806857108 | COM | 34,361 | $2,885,000 | thousands by filing date | |
| GENOCEA BIOSCIENCES INC | 372427104 | COM | 696,273 | $2,869,000 | thousands by filing date | |
| DBV TECHNOLOGIES S A | 23306J101 | ADR | 79,058 | $2,777,000 | thousands by filing date | |
| RETROPHIN INC | 761299106 | COM | 143,974 | $2,725,000 | thousands by filing date | |
| ADVANCE AUTO PARTS INC | 00751Y106 | COM | 16,059 | $2,716,000 | thousands by filing date | |
| TESARO INC | 881569107 | COM | 20,000 | $2,690,000 | thousands by filing date | |
| ISHARES TR | 464287958 | RUS 1000 VAL ETF | 12,000 | $2,682,000 | thousands by filing date | put |
| CLEARSIDE BIOMEDICAL INC | 185063104 | COM | 300,000 | $2,682,000 | thousands by filing date | |
| NICE LTD SPONSORED ADR | 653656108 | ADR | 38,323 | $2,635,000 | thousands by filing date | |
| ACCELERON PHARMA INC | 00434H108 | COM | 100,000 | $2,552,000 | thousands by filing date | |
| Starbucks Corporation | 855244109 | COM | 45,631 | $2,533,000 | thousands by filing date | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 328,029 | $2,526,000 | thousands by filing date | |
| Rocket Pharmaceuticals Inc | 45780V102 | SHS | 401,764 | $2,451,000 | thousands by filing date | |
| AEVI GENOMIC MEDICINE INC | 00835P105 | COM | 450,000 | $2,331,000 | thousands by filing date | |
| PORTOLA PHARMACEUTICALS INC COM | 737010108 | Stock | 100,000 | $2,244,000 | thousands by filing date | |
| KITE PHARMA INC | 49803L109 | COM | 50,000 | $2,242,000 | thousands by filing date | |
| ARDELYX INC | 039697107 | COM | 151,813 | $2,156,000 | thousands by filing date | |
| PARATEK PHARMACEUTICALS INC | 699374302 | Equity | 140,000 | $2,156,000 | thousands by filing date | |
| AVEXIS INC | 05366U100 | COM | 45,000 | $2,148,000 | thousands by filing date | |
| VISTAGEN THERAPEUTICS INC | 92840H202 | COM | 544,100 | $2,029,000 | thousands by filing date | |
| FIVE PRIME THERAPEUTICS INC. | 33830X104 | Common Stock | 40,000 | $2,004,000 | thousands by filing date | |
| ALDEYRA THERAPEUTICS INC | 01438T106 | COM | 368,500 | $1,971,000 | thousands by filing date | |
| SNAP ON INC COM | 833034101 | Stock | 10,972 | $1,879,000 | thousands by filing date | |
| EDGE THERAPEUTICS INC | 279870109 | COM | 150,000 | $1,875,000 | thousands by filing date | |
| FORWARD PHARMA A/S | 34986J105 | SPONSORED ADR | 121,500 | $1,824,000 | thousands by filing date | |
| GLOBAL BLOOD THERAPEUTICS USD | 37890U108 | COM | 125,000 | $1,806,000 | thousands by filing date | |
| MACROGENICS INC | 556099109 | COM | 81,200 | $1,660,000 | thousands by filing date | |
| PTC THERAPEUTICS INC | 69366J200 | COM | 150,000 | $1,637,000 | thousands by filing date | |
| PACIRA BIOSCIENCES INC COM | 695127100 | Stock | 50,000 | $1,615,000 | thousands by filing date | |
| TOWER SEMICONDUCTOR LTD SHS NEW | M87915274 | Stock | 83,940 | $1,597,000 | thousands by filing date | |
| SAPIENS INTERNATIONAL CORP | N7716A151 | SHS | 109,322 | $1,568,000 | thousands by filing date | |
| COGNIZANT TECHNOLOGY SOLUTIONS CL A | 192446102 | Stock | 27,875 | $1,562,000 | thousands by filing date | |
| ORBOTECH LTD | M75253100 | ORD | 45,221 | $1,511,000 | thousands by filing date | |
| META PLATFORMS INC CL A | 30303M102 | COM | 13,062 | $1,503,000 | thousands by filing date | |
| PALATIN TECHNOLOGIES INC | 696077403 | COM PAR $ .01 | 2,906,037 | $1,481,000 | thousands by filing date | |
| CATABASIS PHARMACEUTICALS IN | 14875P107 | COM | 387,943 | $1,400,000 | thousands by filing date | |
| ASTRAZENECA PLC SPONSORED ADR | 046353108 | ADR | 50,000 | $1,366,000 | thousands by filing date | |
| MARINUS PHARMACEUTICALS INC | 56854Q101 | COM | 1,340,588 | $1,354,000 | thousands by filing date | |
| Boeing Company | 097023105 | COM | 8,392 | $1,306,000 | thousands by filing date | |
| REPROS THERAPEUTICS INC | 76028H209 | COM | 978,800 | $1,292,000 | thousands by filing date | |
| SUMMIT THERAPEUTICS INC COM | 86627R102 | Stock | 147,450 | $1,262,000 | thousands by filing date | |
| AXOVANT SCIENCES LTD | G0750W104 | COM | 100,000 | $1,242,000 | thousands by filing date | |
| SYNDAX PHARMACEUTICALS INC | 87164F105 | COM | 166,310 | $1,192,000 | thousands by filing date | |
| PIERIS PHARMACEUTICALS INC | 720795103 | COM | 810,000 | $1,134,000 | thousands by filing date | |
| MasterCard, Inc | 57636Q104 | COM | 10,825 | $1,118,000 | thousands by filing date | |
| MYOKARDIA INC | 62857M105 | COM | 83,240 | $1,078,000 | thousands by filing date | |
| PROQR THERAPEUTICS NV | N71542109 | SHS EURO | 200,000 | $980,000 | thousands by filing date | |
| VTV THERAPEUTICS INC CL A | 918385105 | Stock | 200,000 | $966,000 | thousands by filing date | |
| RA PHARMACEUTICALS INC | 74933V108 | COM | 60,000 | $911,000 | thousands by filing date | |
| Thermo Fisher Scientific Inc. | 883556102 | COM | 6,363 | $898,000 | thousands by filing date | |
| LA JOLLA PHARMACEUTICAL CO | 503459604 | COM PAR $.0001 2 | 50,677 | $888,000 | thousands by filing date | |
| PALO ALTO NETWORKS INC | 697435105 | COM | 7,052 | $882,000 | thousands by filing date | |
| PROSHARES TR | 74347B201 | PSHS ULTSH 20YRS | 18,650 | $761,000 | thousands by filing date | |
| IMMUNE DESIGN CORP. | 45252L103 | Common Stock | 103,000 | $567,000 | thousands by filing date | |
| ONCOBIOLOGICS INC | 68235M105 | COM | 174,477 | $525,000 | thousands by filing date | |
| SUNESIS PHARMACEUTICALS INC | 867328700 | COM | 125,000 | $453,000 | thousands by filing date | |
| MIRATI THERAPEUTICS INC | 60468T105 | COM | 80,528 | $383,000 | thousands by filing date | |
| SOLAREDGE TECHNOLOGIES INC | 83417M104 | COM | 26,203 | $325,000 | thousands by filing date | |
| CABLE ONE INC | 12685J105 | COM | 500 | $311,000 | thousands by filing date | |
| SITEONE LANDSCAPE SUPPLY INC | 82982L103 | COM | 8,820 | $306,000 | thousands by filing date | |
| HORIZON PHARMA PLC | G4617B905 | CALL | 18,100 | $293,000 | thousands by filing date | call |
| UnitedHealth Group Inc | 91324P102 | COM | 1,700 | $272,000 | thousands by filing date | |
| MOHAWK INDS INC | 608190104 | COM | 1,100 | $220,000 | thousands by filing date | |
| Lowes Companies,Inc. | 548661107 | COM | 2,600 | $185,000 | thousands by filing date | |
| SEALED AIR CORP NEW | 81211K100 | COM | 3,500 | $159,000 | thousands by filing date | |
| IGNYTA INC | 451731103 | COM | 22,065 | $117,000 | thousands by filing date | |
| Arbutus Biopharma Corp | 03879J100 | Common Shares, without par value | 22,000 | $54,000 | thousands by filing date |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001178913-17-000411 | this filing | 2017-02-13 | acceptance time not in the bulk data set |