13F-HR filed by SPHERA FUNDS MANAGEMENT LTD.
SPHERA FUNDS MANAGEMENT LTD. filed this 13F-HR for the quarter ended 2016-03-31, filed 2016-05-16, with 90 holding rows worth $461,353,000.
- Accession
- 0001178913-16-005416
- Filer
- CIK 1496201
- Filed
- 2016-05-16
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q1 2016
A holdings report, 91 entries on the cover page, a total value of $461,353,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $461,358,000 with VALUE read as thousands by filing date, 13F file number 028-15863. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerSphera Global Healthcare GP Ltd.028-15864
- included managerSphera Global Healthcare Management LP028-15865
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| SELECT SECTOR SPDR TR | 81369Y959 | PUT | 750,000 | $50,835,000 | thousands by filing date | put |
| Pfizer Inc. | 717081103 | COM | 1,426,612 | $42,285,000 | thousands by filing date | |
| TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS | 881624209 | ADR | 725,200 | $38,805,000 | thousands by filing date | |
| BIOGEN INC COM | 09062X103 | Stock | 118,850 | $30,939,000 | thousands by filing date | |
| ISHARES TR | 464287955 | PUT | 250,000 | $27,658,000 | thousands by filing date | put |
| ALLERGAN PLC | G0177J108 | SHS | 100,000 | $26,803,000 | thousands by filing date | |
| SHIRE PLC | 82481R106 | COMMON STOCK-FO | 188,676 | $16,479,000 | thousands by filing date | |
| Gilead Sciences,Inc. | 375558103 | COM | 172,700 | $15,864,000 | thousands by filing date | |
| MYLAN NV | N59465109 | SHS EURO | 287,827 | $13,326,000 | thousands by filing date | |
| ORMAT TECHNOLOGIES INC | 686688102 | COM | 322,193 | $13,267,000 | thousands by filing date | |
| CELGENE CORP | 151020104 | COM | 100,000 | $10,009,000 | thousands by filing date | |
| ITURAN LOCATION AND CONTROL SHS | M6158M104 | Stock | 471,584 | $9,282,000 | thousands by filing date | |
| ALEXION PHARMACEUTICALS INC | 015351109 | COM | 40,000 | $5,569,000 | thousands by filing date | |
| Visa Inc | 92826C839 | COM | 67,369 | $5,152,000 | thousands by filing date | |
| XLF 260717P00050000 | 81369y955 | PUT | 200,000 | $4,500,000 | thousands by filing date | put |
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 70,000 | $4,394,000 | thousands by filing date | |
| Alphabet Inc. Reg. Shares A | 02079K305 | COM | 5,680 | $4,333,000 | thousands by filing date | |
| VANDA PHARMACEUTICALS INC | 921659108 | COM | 512,051 | $4,281,000 | thousands by filing date | |
| ACADIA PHARMACEUTICALS INC | 004225108 | COM | 150,000 | $4,194,000 | thousands by filing date | |
| SAGE THERAPEUTICS INC | 78667J108 | COM | 123,000 | $3,943,000 | thousands by filing date | |
| ADAMAS PHARMACEUTICALS INC | 00548A106 | COM | 270,000 | $3,904,000 | thousands by filing date | |
| FIVE PRIME THERAPEUTICS INC. | 33830X104 | Common Stock | 80,000 | $3,250,000 | thousands by filing date | |
| ELBIT SYS LTD ORD | M3760D101 | Stock | 34,456 | $3,242,000 | thousands by filing date | |
| ADVANCE AUTO PARTS INC | 00751Y106 | COM | 20,136 | $3,229,000 | thousands by filing date | |
| CHARTER COMMUNICATION - A | 16117M305 | COM | 15,930 | $3,225,000 | thousands by filing date | |
| MARINUS PHARMACEUTICALS INC | 56854Q101 | COM | 570,908 | $3,071,000 | thousands by filing date | |
| PARTNER COMMUNICATIONS CO LT | 70211M109 | ADR | 624,230 | $2,909,000 | thousands by filing date | |
| MACROGENICS INC | 556099109 | COM | 153,000 | $2,869,000 | thousands by filing date | |
| RADIUS HEALTH INC | 750469207 | COM NEW | 90,000 | $2,830,000 | thousands by filing date | |
| PALO ALTO NETWORKS INC | 697435105 | COM | 17,175 | $2,802,000 | thousands by filing date | |
| GENOCEA BIOSCIENCES INC | 372427104 | COM | 361,908 | $2,801,000 | thousands by filing date | |
| NEUROCRINE BIOSCIENCES INC | 64125C109 | COM | 70,000 | $2,769,000 | thousands by filing date | |
| KEMPHARM INC COM NEW | 488445107 | Stock | 183,954 | $2,667,000 | thousands by filing date | |
| AMICUS THERAPEUTICS INC | 03152W109 | COM | 300,000 | $2,535,000 | thousands by filing date | |
| AMICUS THERAPEUTIC | 03152W959 | PUT | 300,000 | $2,535,000 | thousands by filing date | put |
| DERMIRA INC | 24983L104 | COM | 120,000 | $2,482,000 | thousands by filing date | |
| EIGER BIOPHARMACEUTICALS INC | 28249U105 | COM | 147,514 | $2,474,000 | thousands by filing date | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 341,944 | $2,411,000 | thousands by filing date | |
| NEURODERM LTD | M74231107 | ORD SHS | 166,359 | $2,349,000 | thousands by filing date | |
| KITE PHARMA INC | 49803L109 | COM | 50,000 | $2,296,000 | thousands by filing date | |
| ACADIA PHARMACEUTICALS INC | 004225958 | COM | 80,000 | $2,237,000 | thousands by filing date | put |
| FOAMIX PHARMACEUTICALS LTD | M46135105 | SHS | 342,000 | $2,230,000 | thousands by filing date | |
| CHINOOK THERAPEUTICS INC. | 00739L101 | Common Stock | 170,000 | $2,178,000 | thousands by filing date | |
| AIR PRODS & CHEMS INC | 009158106 | COM | 14,672 | $2,114,000 | thousands by filing date | |
| CHIASMA INC | 16706W102 | COM | 230,649 | $2,113,000 | thousands by filing date | |
| FORWARD PHARMA A/S | 34986J105 | SPONSORED ADR | 121,500 | $2,066,000 | thousands by filing date | |
| AGIOS PHARMACEUTICALS INC | 00847X104 | COM | 50,000 | $2,030,000 | thousands by filing date | |
| GLYCOMIMETICS INC | 38000Q102 | COM | 337,911 | $2,014,000 | thousands by filing date | |
| EGALET CORP | 28226B104 | COM | 292,500 | $2,007,000 | thousands by filing date | |
| MELLANOX TECHNOLOGIES LTD | M51363113 | COMMON STOCK | 36,760 | $1,997,000 | thousands by filing date | |
| IMMUNE DESIGN CORP. | 45252L103 | Common Stock | 153,000 | $1,989,000 | thousands by filing date | |
| ACORDA THERAPEUTICS INC | 00484M106 | COM | 73,000 | $1,931,000 | thousands by filing date | |
| ICL GROUP LTD ILS1 | M5920A109 | Common Stock | 437,671 | $1,903,000 | thousands by filing date | |
| HERON THERAPEUTICS INC | 427746102 | COM | 100,000 | $1,899,000 | thousands by filing date | |
| Arbutus Biopharma Corp | 03879J100 | Common Shares, without par value | 454,500 | $1,877,000 | thousands by filing date | |
| Rocket Pharmaceuticals Inc | 45780V102 | SHS | 250,000 | $1,850,000 | thousands by filing date | |
| RAPTOR PHARMACEUTICAL CORP | 75382F106 | COM | 400,000 | $1,840,000 | thousands by filing date | |
| CLOVIS ONCOLOGY INC | 189464100 | COM | 94,500 | $1,814,000 | thousands by filing date | |
| VALEANT PHARMACEUTICALS INTL | 91911K102 | COM | 68,500 | $1,802,000 | thousands by filing date | |
| NICE LTD SPONSORED ADR | 653656108 | ADR | 27,300 | $1,769,000 | thousands by filing date | |
| COLUCID PHARMACEUTICALS INC | 19716T101 | COM | 278,337 | $1,726,000 | thousands by filing date | |
| WABTEC COM | 929740108 | Stock | 21,704 | $1,721,000 | thousands by filing date | |
| PORTOLA PHARMACEUTICALS INC | 737010908 | COM | 80,100 | $1,634,000 | thousands by filing date | call |
| IONIS PHARMACEUTICALS INC COM | 462222100 | Stock | 40,000 | $1,620,000 | thousands by filing date | |
| PTC THERAPEUTICS INC | 69366J200 | COM | 250,000 | $1,610,000 | thousands by filing date | |
| CORVUS PHARMACEUTICALS INC | 221015100 | COM | 110,921 | $1,608,000 | thousands by filing date | |
| CYNAPSUS THERAPEUTICS INC | 23257Y859 | COM PAR NO PAR | 134,037 | $1,595,000 | thousands by filing date | |
| ORBOTECH LTD | M75253100 | ORD | 65,710 | $1,563,000 | thousands by filing date | |
| PIERIS PHARMACEUTICALS INC | 720795103 | COM | 810,000 | $1,539,000 | thousands by filing date | |
| ALDER BIOPHARMACEUTICALS INC | 014339105 | COM | 62,500 | $1,531,000 | thousands by filing date | |
| SUMMIT THERAPEUTICS INC COM | 86627R102 | Stock | 198,863 | $1,392,000 | thousands by filing date | |
| EDGE THERAPEUTICS INC | 279870109 | COM | 150,000 | $1,373,000 | thousands by filing date | |
| BLUEBIRD BIO INC | 09609G100 | COM | 30,000 | $1,275,000 | thousands by filing date | |
| SCYNEXIS INC COM NEW | 811292101 | Common Stock | 304,600 | $1,228,000 | thousands by filing date | |
| TRILLIUM THERAPEUTICS INC COM NEW | 89620X506 | Stock | 132,300 | $1,224,000 | thousands by filing date | |
| PALATIN TECHNOLOGIES INC | 696077403 | COM PAR $ .01 | 2,264,426 | $1,223,000 | thousands by filing date | |
| ABEONA THERAPEUTICS INC | 00289Y107 | COM | 468,050 | $1,198,000 | thousands by filing date | |
| CATABASIS PHARMACEUTICALS IN | 14875P107 | COM | 230,041 | $1,159,000 | thousands by filing date | |
| CATALYST PHARMACEUTICALS INC | 14888U101 | COM | 905,000 | $1,059,000 | thousands by filing date | |
| PORTOLA PHARMACEUTICALS INC COM | 737010108 | Stock | 50,000 | $1,020,000 | thousands by filing date | |
| ALDEYRA THERAPEUTICS INC | 01438T106 | COM | 238,500 | $999,000 | thousands by filing date | |
| AXSOME THERAPEUTICS INC. COM | 05464T104 | Stock | 109,069 | $938,000 | thousands by filing date | |
| MANNKIND CORP | 56400P901 | Option | 463,600 | $746,000 | thousands by filing date | call |
| INTERNET GOLD-GOLDEN LINES | M56595107 | COM | 50,250 | $678,000 | thousands by filing date | |
| OCERA THERAPEUTICS INC COM | 67552A108 | COM | 186,800 | $549,000 | thousands by filing date | |
| NIVALIS THERAPEUTICS INC | 65481J109 | COM | 79,900 | $333,000 | thousands by filing date | |
| STRONGBRIDGE BIOPHARMA PLC | G85347105 | SHS USD | 60,718 | $277,000 | thousands by filing date | |
| TOBIRA THERAPEUTICS INC COM | 88883P101 | COM | 32,300 | $264,000 | thousands by filing date | |
| ELLOMAY CAPITAL LIMITED | M39927120 | SHS | 5,653 | $48,000 | thousands by filing date | |
| TOWER SEMICONDUCTOR LTD SHS NEW | M87915274 | Stock | 0 | $0 | thousands by filing date | Value filed as zero, left out of ratios.Amount filed as zero, left out of ratios. |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001178913-16-005416 | this filing | 2016-05-16 | acceptance time not in the bulk data set |