13F-HR filed by SPHERA FUNDS MANAGEMENT LTD.
SPHERA FUNDS MANAGEMENT LTD. filed this 13F-HR for the quarter ended 2015-06-30, filed 2015-08-06, with 131 holding rows worth $1,020,895,000.
- Accession
- 0001178913-15-002526
- Filer
- CIK 1496201
- Filed
- 2015-08-06
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q2 2015
A holdings report, 133 entries on the cover page, a total value of $1,020,895,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $1,020,903,000 with VALUE read as thousands by filing date, 13F file number 028-15863. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerSphera Global Healthcare GP Ltd.028-15864
- included managerSphera Global Healthcare Management LP028-15865
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| ISHARES TR | 464287955 | PUT | 13,865 | $173,118,000 | thousands by filing date | put |
| ALLERGAN PLC | G0177J108 | SHS | 177,100 | $53,743,000 | thousands by filing date | |
| SPDR SERIES TRUST | 78464A950 | PUT | 2,000 | $50,448,000 | thousands by filing date | put |
| TEVA PHARMACEUTICAL INDS LTD | 881624909 | CALL | 6,500 | $38,415,000 | thousands by filing date | call |
| Gilead Sciences,Inc. | 375558103 | COM | 320,000 | $37,466,000 | thousands by filing date | |
| Pfizer Inc. | 717081103 | COM | 874,013 | $29,306,000 | thousands by filing date | |
| ISHARES TR | 464287956 | ISHARES BIOTECH | 750 | $27,673,000 | thousands by filing date | put |
| AbbVie,Inc. | 00287Y109 | COM | 407,000 | $27,346,000 | thousands by filing date | |
| BIOGEN INC COM | 09062X103 | Stock | 60,730 | $24,531,000 | thousands by filing date | |
| Merck & Co.,Inc. | 58933Y105 | COM | 400,000 | $22,772,000 | thousands by filing date | |
| SELECT SECTOR SPDR TR | 81369Y959 | PUT | 3,000 | $22,317,000 | thousands by filing date | put |
| CELGENE CORP | 151020104 | COM | 160,000 | $18,518,000 | thousands by filing date | |
| PERRIGO CO PLC | G97822903 | SHS | 1,000 | $18,483,000 | thousands by filing date | call |
| BIOMARIN PHARMACEUTICAL INC | 09061G901 | COM | 1,000 | $13,678,000 | thousands by filing date | call |
| MYLAN NV | N59465109 | SHS EURO | 175,000 | $11,876,000 | thousands by filing date | |
| ORMAT TECHNOLOGIES INC | 686688102 | COM | 80,092 | $11,309,000 | thousands by filing date | |
| CLOVIS ONCOLOGY INC | 189464100 | COM | 120,000 | $10,546,000 | thousands by filing date | |
| TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS | 881624209 | ADR | 177,300 | $10,478,000 | thousands by filing date | |
| VALEANT PHARMACEUTICALS INTL | 91911K102 | COM | 45,750 | $10,163,000 | thousands by filing date | |
| NOVARTIS AG SPONSORED ADR | 66987V109 | ADR | 100,000 | $9,834,000 | thousands by filing date | |
| Amgen Inc. | 031162100 | COM | 60,200 | $9,242,000 | thousands by filing date | |
| CONCORDIA HEALTHCARE CORP | 206519100 | COM | 100,000 | $9,025,000 | thousands by filing date | |
| VERINT SYS INC | 92343X100 | COM | 139,434 | $8,470,000 | thousands by filing date | |
| BIOMARIN PHARMACEUTICAL INC | 09061G101 | COM | 60,000 | $8,207,000 | thousands by filing date | |
| CHECK POINT SOFTWARE TECH LTD ORD | M22465104 | Stock | 91,087 | $7,246,000 | thousands by filing date | |
| SHIRE PLC | 82481R106 | COMMON STOCK-FO | 134,751 | $6,866,000 | thousands by filing date | |
| SEATTLE GENETICS INC | 812578102 | COM | 140,000 | $6,776,000 | thousands by filing date | |
| Bristol-Myers Squibb Company | 110122108 | COM | 100,000 | $6,654,000 | thousands by filing date | |
| ALDER BIOPHARMACEUTICALS INC | 014339105 | COM | 125,000 | $6,621,000 | thousands by filing date | |
| VANDA PHARMACEUTICALS INC | 921659108 | COM | 513,390 | $6,515,000 | thousands by filing date | |
| B COMMUNICATIONS LTD | M15629104 | SHS | 5,977,000 | $6,448,000 | thousands by filing date | |
| AMICUS THERAPEUTICS INC | 03152W109 | COM | 450,000 | $6,368,000 | thousands by filing date | |
| AMAG PHARMACEUTICALS INC | 00163U106 | COM | 90,230 | $6,231,000 | thousands by filing date | |
| PROTHENA CORP PLC SHS | G72800108 | Stock | 115,133 | $6,064,000 | thousands by filing date | |
| ARRAY BIOPHARMA INC COM | 04269X105 | Stock | 800,000 | $5,768,000 | thousands by filing date | |
| FORWARD PHARMA A/S | 34986J105 | SPONSORED ADR | 150,000 | $5,708,000 | thousands by filing date | |
| ISHARES INC MSCI GERMANY ETF | 464286806 | MSCI GERMANY ETF | 192,630 | $5,371,000 | thousands by filing date | |
| GW PHARMACEUTICALS PLC | 36197T103 | ADS | 43,500 | $5,344,000 | thousands by filing date | |
| CYNAPSUS THERAPEUTICS INC | 23257Y859 | COM PAR NO PAR | 316,448 | $5,324,000 | thousands by filing date | |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 215,000 | $5,250,000 | thousands by filing date | |
| MEDICINES CO | 584688105 | COM | 180,000 | $5,150,000 | thousands by filing date | |
| TESARO INC | 881569107 | COM | 87,500 | $5,144,000 | thousands by filing date | |
| CATABASIS PHARMACEUTICALS IN | 14875P107 | COM | 446,036 | $5,060,000 | thousands by filing date | |
| UNITED THERAPEUTICS CORP DEL COM | 91307C102 | Stock | 28,840 | $5,017,000 | thousands by filing date | |
| ACORDA THERAPEUTICS INC | 00484M106 | COM | 150,000 | $5,000,000 | thousands by filing date | |
| CATALYST PHARMACEUTICALS INC | 14888U101 | COM | 1,200,000 | $4,956,000 | thousands by filing date | |
| BELLICUM PHARMACEUTICALS INC | 079481107 | COM | 231,514 | $4,924,000 | thousands by filing date | |
| ULTRAGENYX PHARMACEUTICAL IN | 90400D108 | COM | 47,700 | $4,884,000 | thousands by filing date | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 150,000 | $4,565,000 | thousands by filing date | |
| DELPHI AUTOMOTIVE PLC | G27823106 | COMMON STOCK-FO | 53,070 | $4,516,000 | thousands by filing date | |
| ORBOTECH LTD | M75253100 | ORD | 214,922 | $4,470,000 | thousands by filing date | |
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 37,000 | $4,435,000 | thousands by filing date | |
| RELYPSA INC | 759531106 | Common Stock | 132,000 | $4,368,000 | thousands by filing date | |
| KEMPHARM INC COM NEW | 488445107 | Stock | 237,500 | $4,363,000 | thousands by filing date | |
| INTERCEPT PHARMACEUTICALS IN | 45845P108 | COM | 17,500 | $4,224,000 | thousands by filing date | |
| GENOCEA BIOSCIENCES INC | 372427104 | COM | 302,200 | $4,149,000 | thousands by filing date | |
| INTRA-CELLULAR THERAPIES INC | 46116X101 | COMMON STOCK | 128,000 | $4,090,000 | thousands by filing date | |
| BIOTIE THERAPIES OYJ | 09074D103 | SPONSORED ADR | 196,800 | $3,930,000 | thousands by filing date | |
| SPDR INDEX SHS FDS | 78463X202 | EURO STOXX 50 | 104,920 | $3,927,000 | thousands by filing date | |
| PORTOLA PHARMACEUTICALS INC COM | 737010108 | Stock | 86,000 | $3,917,000 | thousands by filing date | |
| MEDIVATION INC | 58501N101 | COM | 34,115 | $3,896,000 | thousands by filing date | |
| FOAMIX PHARMACEUTICALS LTD | M46135105 | SHS | 380,000 | $3,895,000 | thousands by filing date | |
| DEPOMED INC | 249908104 | COM | 180,000 | $3,863,000 | thousands by filing date | |
| NIVALIS THERAPEUTICS INC | 65481J109 | COM | 255,000 | $3,863,000 | thousands by filing date | |
| RECEPTOS, INC. | 756207106 | COMMON STOCK | 20,000 | $3,801,000 | thousands by filing date | |
| SUNESIS PHARMACEUTICALS INC | 867328601 | COM NEW | 1,235,000 | $3,717,000 | thousands by filing date | |
| ATYR PHARMA INC | 002120103 | COM | 209,027 | $3,696,000 | thousands by filing date | |
| SMITH A O CORP COM | 831865209 | Stock | 50,620 | $3,644,000 | thousands by filing date | |
| SPDR SERIES TRUST | 78464A698 | ST STR SP REGBNK | 80,080 | $3,536,000 | thousands by filing date | |
| DYNAVAX TECHNOLOGIES CORP | 268158201 | COM NEW | 150,000 | $3,514,000 | thousands by filing date | |
| SAGE THERAPEUTICS INC | 78667J108 | COM | 48,000 | $3,504,000 | thousands by filing date | |
| KITE PHARMA INC | 49803L109 | COM | 56,970 | $3,473,000 | thousands by filing date | |
| MARINUS PHARMACEUTICALS INC | 56854Q101 | COM | 298,533 | $3,463,000 | thousands by filing date | |
| ARROWHEAD RESEARCH CORP | 042797209 | COM | 475,000 | $3,396,000 | thousands by filing date | |
| HALOZYME THERAPEUTICS INC COM | 40637H109 | Stock | 150,000 | $3,387,000 | thousands by filing date | |
| OCULAR THERAPEUTIX INC | 67576A100 | COM | 160,000 | $3,365,000 | thousands by filing date | |
| PIERIS PHARMACEUTICALS INC | 720795103 | COM | 1,200,000 | $3,300,000 | thousands by filing date | |
| RAPTOR PHARMACEUTICAL CORP | 75382F106 | COM | 206,500 | $3,261,000 | thousands by filing date | |
| THERAPEUTICSMD INC | 88338N107 | COM | 412,500 | $3,242,000 | thousands by filing date | |
| MACROGENICS INC | 556099109 | COM | 85,000 | $3,227,000 | thousands by filing date | |
| TRILLIUM THERAPEUTICS INC COM NEW | 89620X506 | Stock | 147,000 | $3,208,000 | thousands by filing date | |
| PTC THERAPEUTICS INC | 69366J200 | COM | 66,500 | $3,201,000 | thousands by filing date | |
| ACCELERON PHARMA INC | 00434H108 | COM | 100,000 | $3,164,000 | thousands by filing date | |
| VERIFONE SYS INC | 92342Y109 | COM | 93,055 | $3,160,000 | thousands by filing date | |
| UNIQURE NV | N90064101 | SHS | 115,000 | $3,105,000 | thousands by filing date | |
| FIVE PRIME THERAPEUTICS INC. | 33830X104 | Common Stock | 125,000 | $3,105,000 | thousands by filing date | |
| APPLIED GENETIC TECHNOL CORP | 03820J100 | COM | 200,124 | $3,070,000 | thousands by filing date | |
| MELLANOX TECHNOLOGIES LTD | M51363113 | COMMON STOCK | 62,850 | $3,054,000 | thousands by filing date | |
| TEKMIRA PHARMACEUTICALS COR | 87911B209 | COM NEW | 255,000 | $3,024,000 | thousands by filing date | |
| MIRATI THERAPEUTICS INC | 60468T105 | COM | 95,000 | $2,990,000 | thousands by filing date | |
| Apple Inc | 037833100 | COM | 23,223 | $2,913,000 | thousands by filing date | |
| IMMUNE DESIGN CORP. | 45252L103 | Common Stock | 140,000 | $2,891,000 | thousands by filing date | |
| PTC THERAPEUTICS INC | 69366J900 | COM | 600 | $2,888,000 | thousands by filing date | call |
| Starbucks Corporation | 855244109 | COM | 53,583 | $2,873,000 | thousands by filing date | |
| MEDICINES COMPANY | 584688905 | COM | 1,000 | $2,861,000 | thousands by filing date | call |
| Carbylan Therapeutics Inc. | 141384107 | COM | 400,000 | $2,860,000 | thousands by filing date | |
| WIX COM LTD SHS | M98068105 | Stock | 120,305 | $2,842,000 | thousands by filing date | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 422,250 | $2,838,000 | thousands by filing date | |
| COLUCID PHARMACEUTICALS INC | 19716T101 | COM | 317,250 | $2,824,000 | thousands by filing date | |
| ISIS PHARMACEUTICALS INC | 464330109 | COM | 48,000 | $2,762,000 | thousands by filing date | |
| SCYNEXIS INC COM NEW | 811292101 | Common Stock | 313,000 | $2,751,000 | thousands by filing date | |
| OTONOMY INC | 68906L105 | COM | 113,000 | $2,598,000 | thousands by filing date | |
| TREVENA INC | 89532E109 | COM | 410,000 | $2,567,000 | thousands by filing date | |
| ELLOMAY CAPITAL LIMITED | M39927120 | SHS | 246,697 | $2,518,000 | thousands by filing date | |
| SNAP ON INC COM | 833034101 | Stock | 15,340 | $2,443,000 | thousands by filing date | |
| TOBIRA THERAPEUTICS INC COM | 88883P101 | COM | 137,622 | $2,374,000 | thousands by filing date | |
| TETRAPHASE PHARMACEUTICALS INC | 88165N105 | COMMON STOCK | 49,500 | $2,348,000 | thousands by filing date | |
| SUMMIT THERAPEUTICS INC COM | 86627R102 | Stock | 205,200 | $2,280,000 | thousands by filing date | |
| PALATIN TECHNOLOGIES INC | 696077403 | COM PAR $ .01 | 2,540,266 | $2,261,000 | thousands by filing date | |
| WABTEC COM | 929740108 | Stock | 22,365 | $2,108,000 | thousands by filing date | |
| ALDEYRA THERAPEUTICS INC | 01438T106 | COM | 265,000 | $2,056,000 | thousands by filing date | |
| Rocket Pharmaceuticals Inc | 45780V102 | SHS | 380,000 | $1,862,000 | thousands by filing date | |
| CHARTER COMMUNICATION - A | 16117M305 | COM | 10,065 | $1,724,000 | thousands by filing date | |
| TOWERS WATSON & CO | 891894107 | CL A | 12,807 | $1,611,000 | thousands by filing date | |
| EXELIXIS INC COM | 30161Q104 | Stock | 400,000 | $1,504,000 | thousands by filing date | |
| APTOSE BIOSCIENCES INC COM | 03835T200 | Stock | 221,096 | $1,415,000 | thousands by filing date | |
| BROADCOM CORP | 111320107 | CL A | 24,894 | $1,282,000 | thousands by filing date | |
| V F CORP COM | 918204108 | Stock | 17,600 | $1,227,000 | thousands by filing date | |
| NICE LTD SPONSORED ADR | 653656108 | ADR | 18,250 | $1,161,000 | thousands by filing date | |
| IMMUNOMEDICS INC | 452907108 | COM | 245,000 | $995,000 | thousands by filing date | |
| GENVEC INC NEW | 37246C307 | cs | 360,325 | $735,000 | thousands by filing date | |
| IMPAX LABORATORIES INC | 45256B101 | COM | 15,000 | $689,000 | thousands by filing date | |
| SAPIENS INTERNATIONAL CORP | N7716A151 | SHS | 56,420 | $586,000 | thousands by filing date | |
| CARA THERAPEUTICS INC | 140755109 | COM | 46,700 | $567,000 | thousands by filing date | |
| GALECTIN THERAPEUTICS INC | 363225202 | COMMON STOCK | 205,000 | $560,000 | thousands by filing date | |
| Adobe Systems Inc | 98979H103 | COM | 62,300 | $452,000 | thousands by filing date | |
| AURIS MED HLDG AG | H03579101 | COM | 63,967 | $316,000 | thousands by filing date | |
| PERRIGO CO PLC SHS | G97822103 | Stock | 273 | $246,000 | thousands by filing date | |
| CONCERT PHARMACEUTICALS INC | 206022105 | COM | 15,858 | $236,000 | thousands by filing date | |
| Transition Therapeutics, Inc. | 893716209 | COM | 70,273 | $148,000 | thousands by filing date | |
| LUMENIS LTD | M6778Q121 | SHS CL B | 245 | $0 | thousands by filing date | Value filed as zero, left out of ratios. |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001178913-15-002526 | this filing | 2015-08-06 | acceptance time not in the bulk data set |