13F-HR filed by SPHERA FUNDS MANAGEMENT LTD.
SPHERA FUNDS MANAGEMENT LTD. filed this 13F-HR for the quarter ended 2014-12-31, filed 2015-02-12, with 125 holding rows worth $589,980,000.
- Accession
- 0001178913-15-000425
- Filer
- CIK 1496201
- Filed
- 2015-02-12
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2014
A holdings report, 128 entries on the cover page, a total value of $589,980,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $586,983,000 with VALUE read as thousands by filing date, 13F file number 028-15863. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerSphera Global Healthcare GP Ltd.028-15864
- included managerSphera Global Healthcare Management LP028-15865
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| NOVARTIS AG SPONSORED ADR | 66987V109 | ADR | 439,621 | $40,846,000 | thousands by filing date | |
| ACTAVIS PLC | G0083B108 | SHS | 107,100 | $27,569,000 | thousands by filing date | |
| Pfizer Inc. | 717081103 | COM | 874,013 | $27,226,000 | thousands by filing date | |
| TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS | 881624209 | ADR | 396,269 | $22,790,000 | thousands by filing date | |
| SALIX PHARMACEUTICALS INC | 795435106 | COM | 158,500 | $18,218,000 | thousands by filing date | |
| Gilead Sciences,Inc. | 375558103 | COM | 190,000 | $17,909,000 | thousands by filing date | |
| SHIRE PLC | 82481R106 | COMMON STOCK-FO | 224,751 | $15,886,000 | thousands by filing date | |
| VALEANT PHARMACEUTICALS INTL | 91911K102 | COM | 98,550 | $14,103,000 | thousands by filing date | |
| BIOGEN INC COM | 09062X103 | Stock | 40,000 | $13,578,000 | thousands by filing date | |
| ISRAMCO INC | 465141406 | COM | 64,958,387 | $11,134,000 | thousands by filing date | Value about 1/1,000 of the price other filers imply, kept as filed and left out of ratios. |
| UNITED THERAPEUTICS CORP DEL COM | 91307C102 | Stock | 73,840 | $9,562,000 | thousands by filing date | |
| MERCK & CO INC | 058933Y10 | COM | 167,530 | $9,514,000 | thousands by filing date | |
| Mallinckrodt Plc | G5785G107 | SHS | 90,940 | $9,006,000 | thousands by filing date | |
| Bristol-Myers Squibb Company | 110122108 | COM | 150,000 | $8,855,000 | thousands by filing date | |
| ELBIT SYS LTD ORD | M3760D101 | Stock | 144,759 | $8,853,000 | thousands by filing date | |
| VERINT SYS INC | 92343X100 | COM | 146,108 | $8,515,000 | thousands by filing date | |
| ALLERGAN INC | 18490902 | CALL | 250,000 | $8,238,000 | thousands by filing date | callThe CUSIP as filed is malformed. |
| BIOMARIN PHARMACEUTICAL INC | 09061G101 | COM | 80,000 | $7,232,000 | thousands by filing date | |
| BELLICUM PHARMACEUTICALS INC | 79481107 | COM | 331,514 | $6,956,000 | thousands by filing date | The CUSIP as filed is malformed. |
| iShares Russell 2000 ETF | 464287655 | SHS | 54,300 | $6,495,000 | thousands by filing date | |
| KITE PHARMA INC | 49803L109 | COM | 110,970 | $6,400,000 | thousands by filing date | |
| SANOFI | 80105N113 | COMMON STOCK-FO | 67,960 | $6,222,000 | thousands by filing date | |
| ASTRAZENECA PLC | 46353108 | ADR | 86,637 | $6,098,000 | thousands by filing date | The CUSIP as filed is malformed. |
| Eli Lilly and Company | 532457108 | COM | 87,100 | $6,009,000 | thousands by filing date | |
| PHARMACYCLICS INC | 716933106 | COM | 48,840 | $5,971,000 | thousands by filing date | |
| APPLE INC | 37833100 | COM | 52,803 | $5,828,000 | thousands by filing date | The CUSIP as filed is malformed. |
| AUSPEX PHARMACE | 05211J102 | Common Stock | 110,074 | $5,777,000 | thousands by filing date | |
| PTC THERAPEUTICS INC | 69366J200 | COM | 110,000 | $5,695,000 | thousands by filing date | |
| MYLAN INC | 628530107 | COM | 97,100 | $5,474,000 | thousands by filing date | |
| AMGEN INC | 31162900 | COM | 120,200 | $5,457,000 | thousands by filing date | callThe CUSIP as filed is malformed. |
| AMAG PHARMACEUTICALS INC | 00163U106 | COM | 125,230 | $5,337,000 | thousands by filing date | |
| MEDIVATION INC | 58501N101 | COM | 53,115 | $5,291,000 | thousands by filing date | |
| VANDA PHARMACEUTICALS INC | 921659108 | COM | 368,390 | $5,275,000 | thousands by filing date | |
| Financial Select Sector SPDR Fund | 81369Y605 | SHS | 210,000 | $5,193,000 | thousands by filing date | |
| TOWERS WATSON & CO | 891894107 | CL A | 42,350 | $4,793,000 | thousands by filing date | |
| TJX Companies Inc | 872540109 | COM | 67,630 | $4,638,000 | thousands by filing date | |
| ARRAY BIOPHARMA INC COM | 04269X105 | Stock | 973,922 | $4,607,000 | thousands by filing date | |
| CLOVIS ONCOLOGY INC | 189464100 | COM | 81,955 | $4,589,000 | thousands by filing date | |
| AMICUS THERAPEUTICS INC | 03152W109 | COM | 550,000 | $4,576,000 | thousands by filing date | |
| DYAX CORP | 26746E103 | COM | 317,556 | $4,465,000 | thousands by filing date | |
| GLAXOSMITHKLINE PLC-ADR | 37733W105 | SPONSORED ADR | 98,200 | $4,197,000 | thousands by filing date | |
| FORWARD PHARMA A/S | 34986J105 | SPONSORED ADR | 200,000 | $4,166,000 | thousands by filing date | |
| ORBOTECH LTD | M75253100 | ORD | 280,872 | $4,157,000 | thousands by filing date | |
| GILEAD SCIENCES INC | 375558903 | COM | 394,200 | $3,954,000 | thousands by filing date | call |
| CYTOKINETICS INC | 23282W605 | COM NEW | 493,212 | $3,951,000 | thousands by filing date | |
| RELYPSA INC | 759531106 | Common Stock | 127,100 | $3,915,000 | thousands by filing date | |
| BROADCOM CORP | 111320107 | CL A | 88,800 | $3,848,000 | thousands by filing date | |
| PUMA BIOTECHNOLOGY INC | 74587V107 | COMMON STOCK | 20,296 | $3,841,000 | thousands by filing date | |
| CYMABAY THERAPEUTICS INC | 23257D103 | COM | 390,355 | $3,837,000 | thousands by filing date | |
| ITURAN LOCATION AND CONTROL SHS | M6158M104 | Stock | 168,203 | $3,714,000 | thousands by filing date | |
| RECEPTOS, INC. | 756207106 | COMMON STOCK | 30,000 | $3,675,000 | thousands by filing date | |
| Vertex Pharmaceuticals Incorporated | 92532F100 | COM | 30,000 | $3,564,000 | thousands by filing date | |
| CVS Health Corporation | 126650100 | COM | 36,610 | $3,526,000 | thousands by filing date | |
| APPLIED GENETIC TECHNOL CORP | 03820J100 | COM | 165,124 | $3,471,000 | thousands by filing date | |
| AEGERION PHARMACEUTICALS INC | 00767E102 | COM | 160,000 | $3,350,000 | thousands by filing date | |
| Health Care Select Sector SPDR Fund | 81369Y209 | SHS | 48,853 | $3,341,000 | thousands by filing date | |
| TREVENA INC | 89532E109 | COM | 549,811 | $3,288,000 | thousands by filing date | |
| ACORDA THERAPEUTICS INC | 00484M106 | COM | 79,105 | $3,233,000 | thousands by filing date | |
| CATALYST PHARMACEUTICALS INC | 14888U101 | COM | 1,060,000 | $3,148,000 | thousands by filing date | |
| MARINUS PHARMACEUTICALS INC | 56854Q101 | COM | 293,533 | $3,094,000 | thousands by filing date | |
| Union Pacific Corporation | 907818108 | COM | 25,689 | $3,060,000 | thousands by filing date | |
| SANGAMO THERAPEUTICS INC | 800677106 | COM | 200,000 | $3,042,000 | thousands by filing date | |
| MACROGENICS INC | 556099109 | COM | 84,198 | $2,953,000 | thousands by filing date | |
| Arrowhead Research Corp | 42797209 | COM NEW | 400,000 | $2,952,000 | thousands by filing date | The CUSIP as filed is malformed. |
| CELLADON CORP | 15117E107 | Cmn | 150,656 | $2,942,000 | thousands by filing date | |
| SAGE THERAPEUTICS INC | 78667J108 | COM | 79,724 | $2,918,000 | thousands by filing date | |
| DICERNA PHARMACEUTICALS INC | 253031108 | COM | 176,802 | $2,912,000 | thousands by filing date | |
| Alder Biopharmaceuticals Inc. | 14339105 | Com | 100,000 | $2,909,000 | thousands by filing date | The CUSIP as filed is malformed. |
| SNAP ON INC COM | 833034101 | Stock | 21,140 | $2,891,000 | thousands by filing date | |
| EXPRESS SCRIPTS HLDG CO | 30219G108 | COM | 33,966 | $2,876,000 | thousands by filing date | |
| NPS PHARMACEUTICALS INC | 62936P103 | COM | 80,000 | $2,862,000 | thousands by filing date | |
| KERYX BIOPHARMACEUTICALS | 492515101 | COMMON STOCK | 200,000 | $2,830,000 | thousands by filing date | |
| PROQR THERAPEUTICS NV | N71542109 | SHS EURO | 130,000 | $2,817,000 | thousands by filing date | |
| MEDICINES CO | 584688105 | COM | 100,000 | $2,767,000 | thousands by filing date | |
| OCERA THERAPEUTICS INC COM | 67552A108 | COM | 421,254 | $2,683,000 | thousands by filing date | |
| TEKMIRA PHARMACEUTICALS COR | 87911B209 | COM NEW | 175,000 | $2,651,000 | thousands by filing date | |
| AERIE PHARMACEUTICALS INC | 00771V108 | COM | 88,516 | $2,584,000 | thousands by filing date | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 175,000 | $2,532,000 | thousands by filing date | |
| UNIQURE NV | N90064101 | SHS | 168,415 | $2,494,000 | thousands by filing date | |
| B COMMUNICATIONS LTD | M15629104 | SHS | 134,174 | $2,418,000 | thousands by filing date | |
| CEMPRA INC | 15130J109 | COM | 100,000 | $2,351,000 | thousands by filing date | |
| TOKAI PHARMACEUTICALS INC COM | 88907J107 | Stock | 153,841 | $2,268,000 | thousands by filing date | |
| ZAFGEN INC | 98885E103 | COM | 72,100 | $2,224,000 | thousands by filing date | |
| CSX Corporation | 126408103 | COM | 59,648 | $2,161,000 | thousands by filing date | |
| ORMAT TECHNOLOGIES INC | 686688102 | COM | 309,000 | $2,132,000 | thousands by filing date | |
| VITAL THERAPIES INC | 92847R104 | COM | 81,900 | $2,042,000 | thousands by filing date | |
| ENANTA PHARMACEUTICALS INC | 29251M106 | COM | 40,000 | $2,034,000 | thousands by filing date | |
| NICE LTD SPONSORED ADR | 653656108 | ADR | 39,652 | $2,008,000 | thousands by filing date | |
| CONCERT PHARMACEUTICALS INC | 206022105 | COM | 150,000 | $1,998,000 | thousands by filing date | |
| PORTOLA PHARMACEUTICALS INC COM | 737010108 | Stock | 70,000 | $1,982,000 | thousands by filing date | |
| ELLOMAY CAPITAL LIMITED | M39927120 | SHS | 203,778 | $1,977,000 | thousands by filing date | |
| Starbucks Corporation | 855244109 | COM | 24,000 | $1,969,000 | thousands by filing date | |
| LA JOLLA PHARMACEUTICAL CO | 503459604 | COM PAR $.0001 2 | 100,230 | $1,849,000 | thousands by filing date | |
| TEVA PHARMACEUTICAL INDS LTD | 881624909 | CALL | 464,200 | $1,801,000 | thousands by filing date | call |
| CTI BIOPHARMA CORP COM NEW | 12648L106 | Stock | 750,000 | $1,770,000 | thousands by filing date | |
| INTERCEPT PHARMACEUTICALS IN | 45845P108 | COM | 10,000 | $1,560,000 | thousands by filing date | |
| Check Point Software Technologies Ltd | 162825103 | COM | 19,688 | $1,547,000 | thousands by filing date | |
| ACHILLION PHARMACEUTICALS IN | 00448Q201 | COM | 125,538 | $1,538,000 | thousands by filing date | |
| VALEANT PHARMACEUTICALS INTE | 91911K902 | COM | 97,200 | $1,395,000 | thousands by filing date | call |
| AMGEN INC. | 31162100 | COM | 8,550 | $1,362,000 | thousands by filing date | The CUSIP as filed is malformed. |
| PROTHENA CORP PLC SHS | G72800108 | Stock | 62,632 | $1,300,000 | thousands by filing date | |
| WIX COM LTD SHS | M98068105 | Stock | 59,108 | $1,241,000 | thousands by filing date | |
| IGNYTA INC | 451731103 | COM | 179,055 | $1,227,000 | thousands by filing date | |
| GENVEC INC NEW | 37246C307 | cs | 558,325 | $1,195,000 | thousands by filing date | |
| MANNKIND CORP COMMON STOCK | 56400P951 | Cmn | 300,000 | $1,155,000 | thousands by filing date | put |
| Medgenics Inc New | 58436Q203 | COM NEW | 225,000 | $1,139,000 | thousands by filing date | |
| NEUROCRINE BIOSCIENCES INC | 64125C109 | COM | 50,000 | $1,117,000 | thousands by filing date | |
| KAMADA LTD | M6240T109 | SHS | 293,727 | $1,089,000 | thousands by filing date | |
| SESEN BIO, INC. | 286221106 | COM | 87,110 | $1,035,000 | thousands by filing date | |
| REPROS THERAPEUTICS INC | 76028H209 | COM | 100,000 | $997,000 | thousands by filing date | |
| NEWLINK GENETICS CORP | 651511107 | COM | 25,000 | $994,000 | thousands by filing date | |
| ZS PHARMA INC | 98979G105 | Common Stock | 20,682 | $860,000 | thousands by filing date | |
| ONCOTHYREON INC | 682324108 | COM | 428,000 | $813,000 | thousands by filing date | |
| JUNO THERAPEUTICS INC | 48205A109 | COM | 15,000 | $783,000 | thousands by filing date | |
| MAST THERAPEUTICS INC | 576314108 | COM | 1,374,900 | $770,000 | thousands by filing date | |
| PALATIN TECHNOLOGIES INC | 696077403 | COM PAR $ .01 | 1,040,266 | $759,000 | thousands by filing date | |
| ACELRX PHARMACEUTICALS INC | 00444T100 | COM | 100,000 | $673,000 | thousands by filing date | |
| ARDELYX INC | 39697107 | COM | 32,700 | $618,000 | thousands by filing date | The CUSIP as filed is malformed. |
| KALOBIOS PHARMACEUTICALS INC | 48344T100 | COM | 349,560 | $605,000 | thousands by filing date | |
| MELLANOX TECHNOLOGIES LTD | M51363113 | COMMON STOCK | 12,517 | $535,000 | thousands by filing date | |
| ICL GROUP LTD ILS1 | M5920A109 | Common Stock | 40,116 | $291,000 | thousands by filing date | |
| Alcobra Ltd | M2239P109 | SHS | 38,500 | $144,000 | thousands by filing date | |
| SELECT SECTOR SPDR TR | 81369Y956 | Option | 50,000 | $116,000 | thousands by filing date | put |
| NOVAVAX INC | 670002104 | COMMON STOCK | 1,543 | $9,000 | thousands by filing date | |
| GLAXOSMITHKLINE PLC-SPON ADR | 37733W905 | COM | 291,300 | $7,000 | thousands by filing date | call |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001178913-15-000425 | this filing | 2015-02-12 | acceptance time not in the bulk data set |