13F-HR/A filed by SPHERA FUNDS MANAGEMENT LTD.
SPHERA FUNDS MANAGEMENT LTD. filed this 13F-HR/A for the quarter ended 2014-09-30, filed 2014-11-20, with 128 holding rows worth $809,455,000.
- Accession
- 0001178913-14-003634
- Filer
- CIK 1496201
- Filed
- 2014-11-20
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q3 2014
A holdings report, amendment of type restatement, 132 entries on the cover page, a total value of $809,455,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $809,459,000 with VALUE read as thousands by filing date, 13F file number 028-15863. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerSphera Global Healthcare GP Ltd.028-15864
- included managerSphera Global Healthcare Management LP028-15865
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| NOVARTIS AG SPONSORED ADR | 66987V109 | ADR | 478,921 | $45,179,000 | thousands by filing date | |
| SPDR SERIES TRUST | 78464A950 | PUT | 200,000 | $39,404,000 | thousands by filing date | put |
| Pfizer Inc. | 717081103 | COM | 1,274,013 | $37,673,000 | thousands by filing date | |
| TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS | 881624209 | ADR | 647,438 | $34,845,000 | thousands by filing date | |
| SELECT SECTOR SPDR TR | 81369Y959 | PUT | 485,500 | $31,028,000 | thousands by filing date | put |
| ACTAVIS PLC | G0083B108 | SHS | 122,100 | $29,460,000 | thousands by filing date | |
| Merck & Co.,Inc. | 58933Y105 | COM | 417,530 | $24,751,000 | thousands by filing date | |
| AbbVie,Inc. | 00287Y109 | COM | 403,550 | $23,309,000 | thousands by filing date | |
| ALLERGAN INC. | 18490102 | COM | 128,840 | $22,958,000 | thousands by filing date | The CUSIP as filed is malformed. |
| SHIRE PLC | 82481R106 | COMMON STOCK-FO | 259,085 | $22,429,000 | thousands by filing date | |
| ISRAMCO INC | 465141406 | COM | 103,111,944 | $22,136,000 | thousands by filing date | Value about 1/1,000 of the price other filers imply, kept as filed and left out of ratios. |
| Johnson & Johnson | 478160104 | COM | 207,406 | $22,107,000 | thousands by filing date | |
| GILEAD SCIENCES INC | 375558903 | COM | 194,200 | $20,673,000 | thousands by filing date | call |
| TEVA PHARMACEUTICAL INDS LTD | 881624909 | CALL | 375,200 | $20,167,000 | thousands by filing date | call |
| Vertex Pharmaceuticals Incorporated | 92532F100 | COM | 150,000 | $16,847,000 | thousands by filing date | |
| GLAXOSMITHKLINE PLC-SPON ADR | 37733W905 | COM | 291,300 | $13,391,000 | thousands by filing date | call |
| VALEANT PHARMACEUTICALS INTL | 91911K102 | COM | 98,550 | $12,930,000 | thousands by filing date | |
| VALEANT PHARMACEUTICALS INTE | 91911K902 | COM | 97,200 | $12,753,000 | thousands by filing date | call |
| Mallinckrodt Plc | G5785G107 | SHS | 135,940 | $12,255,000 | thousands by filing date | |
| UNITED THERAPEUTICS CORP DEL COM | 91307C102 | Stock | 88,840 | $11,429,000 | thousands by filing date | |
| ICL GROUP LTD ILS1 | M5920A109 | Common Stock | 1,380,000 | $9,977,000 | thousands by filing date | |
| ELBIT SYS LTD ORD | M3760D101 | Stock | 144,759 | $8,974,000 | thousands by filing date | |
| ORBOTECH LTD | M75253100 | ORD | 571,532 | $8,901,000 | thousands by filing date | |
| BIOMARIN PHARMACEUTICAL INC | 09061G101 | COM | 121,970 | $8,801,000 | thousands by filing date | |
| ASTRAZENECA PLC | 46353108 | ADR | 120,000 | $8,573,000 | thousands by filing date | The CUSIP as filed is malformed. |
| VERINT SYS INC | 92343X100 | COM | 151,468 | $8,423,000 | thousands by filing date | |
| SANOFI | 80105N113 | COMMON STOCK-FO | 67,960 | $7,689,000 | thousands by filing date | Value about 1,000 times the price other filers imply, kept as filed and left out of ratios. |
| SALIX PHARMACEUTICALS LTD | 795435906 | Cmn | 48,500 | $7,578,000 | thousands by filing date | call |
| PUMA BIOTECHNOLOGY INC | 74587V107 | COMMON STOCK | 30,296 | $7,228,000 | thousands by filing date | |
| ASTRAZENECA PLC | 46353908 | SPONSORED ADR | 97,100 | $6,937,000 | thousands by filing date | callThe CUSIP as filed is malformed. |
| AMGEN INC. | 31162100 | COM | 48,550 | $6,819,000 | thousands by filing date | The CUSIP as filed is malformed. |
| ACORDA THERAPEUTICS INC | 00484M106 | COM | 199,105 | $6,746,000 | thousands by filing date | |
| Eli Lilly and Company | 532457108 | COM | 97,100 | $6,297,000 | thousands by filing date | |
| MEDIVATION INC | 58501N101 | COM | 63,115 | $6,240,000 | thousands by filing date | |
| B COMMUNICATIONS LTD | M15629104 | SHS | 321,431 | $6,175,000 | thousands by filing date | |
| MEDASSETS INC | 584045108 | COM | 433,889 | $6,103,000 | thousands by filing date | |
| SEATTLE GENETICS INC | 812578102 | COM | 155,360 | $5,776,000 | thousands by filing date | |
| DYAX CORP | 26746E103 | COM | 517,556 | $5,238,000 | thousands by filing date | |
| APPLE INC | 37833100 | COM | 50,045 | $5,042,000 | thousands by filing date | The CUSIP as filed is malformed. |
| ITURAN LOCATION AND CONTROL SHS | M6158M104 | Stock | 231,115 | $4,861,000 | thousands by filing date | |
| AMAG PHARMACEUTICALS INC | 00163U106 | COM | 150,230 | $4,794,000 | thousands by filing date | |
| CLOVIS ONCOLOGY INC | 189464100 | COM | 101,955 | $4,625,000 | thousands by filing date | |
| PHARMACYCLICS INC | 716933106 | COM | 38,840 | $4,561,000 | thousands by filing date | |
| CSX Corporation | 126408103 | COM | 139,675 | $4,478,000 | thousands by filing date | |
| GLAXOSMITHKLINE PLC-ADR | 37733W105 | SPONSORED ADR | 97,100 | $4,464,000 | thousands by filing date | |
| MYLAN INC | 628530107 | COM | 97,100 | $4,417,000 | thousands by filing date | |
| AUSPEX PHARMACE | 05211J102 | Common Stock | 165,074 | $4,237,000 | thousands by filing date | |
| BROADCOM CORP | 111320107 | CL A | 99,360 | $4,016,000 | thousands by filing date | |
| APPLIED GENETIC TECHNOL CORP | 03820J100 | COM | 210,724 | $3,922,000 | thousands by filing date | |
| NPS PHARMACEUTICALS INC | 62936P103 | COM | 139,420 | $3,625,000 | thousands by filing date | |
| Union Pacific Corporation | 907818108 | COM | 32,312 | $3,503,000 | thousands by filing date | |
| TOKAI PHARMACEUTICALS INC COM | 88907J107 | Stock | 230,000 | $3,482,000 | thousands by filing date | |
| INTERCEPT PHARMACEUTICALS IN | 45845P108 | COM | 14,565 | $3,447,000 | thousands by filing date | |
| PROQR THERAPEUTICS NV | N71542109 | SHS EURO | 200,000 | $3,438,000 | thousands by filing date | |
| AERIE PHARMACEUTICALS INC | 00771V108 | COM | 163,516 | $3,383,000 | thousands by filing date | |
| CYMABAY THERAPEUTICS INC | 23257D103 | COM | 490,355 | $3,354,000 | thousands by filing date | |
| CVS Health Corporation | 126650100 | COM | 39,810 | $3,168,000 | thousands by filing date | |
| V F CORP COM | 918204108 | Stock | 47,900 | $3,163,000 | thousands by filing date | |
| RADIUS HEALTH INC | 750469207 | COM NEW | 150,000 | $3,150,000 | thousands by filing date | |
| SALIX PHARMACEUTICALS INC | 795435106 | COM | 20,000 | $3,125,000 | thousands by filing date | |
| Health Care Select Sector SPDR Fund | 81369Y209 | SHS | 48,853 | $3,122,000 | thousands by filing date | |
| ARRAY BIOPHARMA INC COM | 04269X105 | Stock | 873,922 | $3,120,000 | thousands by filing date | |
| ACCELERON PHARMA INC | 00434H108 | COM | 100,000 | $3,024,000 | thousands by filing date | |
| INCYTE CORP COM | 45337C102 | Stock | 61,173 | $3,001,000 | thousands by filing date | |
| AVANIR PHARMACEUTICALS INC | 05348P401 | CL A NEW | 250,000 | $2,980,000 | thousands by filing date | |
| TJX COS INC NEW | 872540909 | CALL | 50,000 | $2,959,000 | thousands by filing date | call |
| Schlumberger Limited | 806857108 | COM | 28,790 | $2,928,000 | thousands by filing date | |
| YUM BRANDS INC COM | 988498101 | Stock | 39,910 | $2,873,000 | thousands by filing date | |
| PTC THERAPEUTICS INC | 69366J200 | COM | 63,625 | $2,800,000 | thousands by filing date | |
| TOWERS WATSON & CO | 891894107 | CL A | 28,000 | $2,786,000 | thousands by filing date | |
| SAGE THERAPEUTICS INC | 78667J108 | COM | 87,924 | $2,770,000 | thousands by filing date | |
| OTONOMY INC | 68906L105 | COM | 111,085 | $2,666,000 | thousands by filing date | |
| NICE LTD SPONSORED ADR | 653656108 | ADR | 64,542 | $2,622,000 | thousands by filing date | |
| GOOGLE INC | 38259P706 | CL C | 4,540 | $2,621,000 | thousands by filing date | |
| COLGATE PALMOLIVE CO COM | 194162103 | Stock | 40,099 | $2,615,000 | thousands by filing date | |
| IRONWOOD PHARMACEUTICALS INC | 46333X108 | COMMON STOCK | 194,200 | $2,516,000 | thousands by filing date | |
| CATALYST PHARMACEUTICALS INC | 14888U101 | COM | 685,500 | $2,276,000 | thousands by filing date | |
| VANDA PHARMACEUTICALS INC | 921659108 | COM | 218,390 | $2,267,000 | thousands by filing date | |
| MACROGENICS INC | 556099109 | COM | 107,781 | $2,253,000 | thousands by filing date | |
| 38259p508 | COM | 3,784 | $2,227,000 | thousands by filing date | ||
| LA JOLLA PHARMACEUTICAL CO | 503459604 | COM PAR $.0001 2 | 223,330 | $2,146,000 | thousands by filing date | |
| TREVENA INC | 89532E109 | COM | 331,111 | $2,126,000 | thousands by filing date | |
| ARENA PHARMACEUTICALS INC. | 40047102 | COM | 500,000 | $2,095,000 | thousands by filing date | The CUSIP as filed is malformed. |
| RELYPSA INC | 759531106 | Common Stock | 97,100 | $2,048,000 | thousands by filing date | |
| AKEBIA THERAPEUTICS INC | 00972D105 | COMMON STOCK | 89,817 | $1,988,000 | thousands by filing date | |
| IMMUNOMEDICS INC | 452907108 | COM | 534,050 | $1,987,000 | thousands by filing date | |
| ACTINIUM PHARMACEUTICALS INC | 00507W107 | COM | 291,300 | $1,952,000 | thousands by filing date | |
| SNAP ON INC COM | 833034101 | Stock | 16,100 | $1,949,000 | thousands by filing date | |
| CELLADON CORP | 15117E107 | Cmn | 185,656 | $1,942,000 | thousands by filing date | |
| KITE PHARMA INC | 49803L109 | COM | 67,970 | $1,937,000 | thousands by filing date | |
| MasterCard, Inc | 57636Q104 | COM | 26,000 | $1,922,000 | thousands by filing date | |
| BLUEBIRD BIO INC | 09609G100 | COM | 53,405 | $1,916,000 | thousands by filing date | |
| ZAFGEN INC | 98885E103 | COM | 97,100 | $1,908,000 | thousands by filing date | |
| Alder Biopharmaceuticals Inc. | 14339105 | Com | 150,000 | $1,902,000 | thousands by filing date | The CUSIP as filed is malformed. |
| MARINUS PHARMACEUTICALS INC | 56854Q101 | COM | 293,533 | $1,899,000 | thousands by filing date | |
| ELLOMAY CAPITAL LIMITED | M39927120 | SHS | 191,202 | $1,891,000 | thousands by filing date | |
| ATRIUM THERAPEUTICS INC | N71546100 | COM | 219,345 | $1,849,000 | thousands by filing date | |
| ONCOMED PHARMACEUTICALS INC COM | 68234X102 | Stock | 97,100 | $1,838,000 | thousands by filing date | |
| MANNKIND CORP COMMON STOCK | 56400P951 | Cmn | 300,000 | $1,773,000 | thousands by filing date | put |
| TJX Companies Inc | 872540109 | COM | 27,600 | $1,633,000 | thousands by filing date | |
| IGNYTA INC | 451731103 | COM | 199,055 | $1,604,000 | thousands by filing date | |
| ACELRX PHARMACEUTICALS INC | 00444T100 | COM | 289,849 | $1,591,000 | thousands by filing date | |
| OCERA THERAPEUTICS INC COM | 67552A108 | COM | 321,254 | $1,574,000 | thousands by filing date | |
| RECEPTOS, INC. | 756207106 | COMMON STOCK | 25,000 | $1,553,000 | thousands by filing date | |
| EPIZYME INC | 29428V104 | COM | 50,000 | $1,356,000 | thousands by filing date | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 363,212 | $1,279,000 | thousands by filing date | |
| GENVEC INC NEW | 37246C307 | cs | 558,325 | $1,161,000 | thousands by filing date | |
| AURIS MED HLDG AG | H03579101 | COM | 191,300 | $1,111,000 | thousands by filing date | |
| BIOBLAST PHARMA LTD | M20156101 | SHS | 150,000 | $1,091,000 | thousands by filing date | |
| PALATIN TECHNOLOGIES INC | 696077403 | COM PAR $ .01 | 1,084,466 | $1,009,000 | thousands by filing date | |
| AFFIMED N V | N01045108 | COM | 150,000 | $945,000 | thousands by filing date | |
| DISCOVERY LABORATORIES INC N | 254668403 | COM NEW | 485,500 | $893,000 | thousands by filing date | |
| ALCOBRA LTD | M2239P909 | SHS | 56,100 | $866,000 | thousands by filing date | call |
| ONCOTHYREON INC | 682324108 | COM | 428,000 | $822,000 | thousands by filing date | |
| ZS PHARMA INC | 98979G105 | Common Stock | 20,682 | $811,000 | thousands by filing date | |
| TETRALOGIC PHARMACEUTICALS COR | 88165U109 | COMMON | 194,200 | $808,000 | thousands by filing date | |
| PROTHENA CORP PLC SHS | G72800108 | Stock | 29,907 | $663,000 | thousands by filing date | |
| STEMCELLS INC | 85857R204 | COM NEW | 485,500 | $612,000 | thousands by filing date | |
| KALOBIOS PHARMACEUTICALS INC | 48344T100 | COM | 349,560 | $542,000 | thousands by filing date | |
| ORMAT TECHNOLOGIES INC | 686688102 | COM | 19,889 | $522,000 | thousands by filing date | |
| BIOLINERX LTD-SPONS ADR | 09071M106 | SPON | 193,284 | $298,000 | thousands by filing date | |
| CONCERT PHARMACEUTICALS INC | 206022105 | COM | 22,700 | $286,000 | thousands by filing date | |
| BRAINSTORM CELL THERAPEUTICS | 10501E201 | COM | 63,331 | $265,000 | thousands by filing date | |
| SUMMIT FINL GROUP INC | 86606G101 | COM | 25,000 | $63,000 | thousands by filing date | |
| MACROCURE LTD | M67872107 | SHS | 7,100 | $51,000 | thousands by filing date | |
| TETRAPHASE PHARMACEUTICALS INC | 88165N105 | COMMON STOCK | 2,365 | $47,000 | thousands by filing date | |
| AUXILIUM PHARMACEUTICALS | 05334D107 | COMMON STOCK | 1,000 | $30,000 | thousands by filing date | |
| AGIOS PHARMACEUTICALS INC | 00847X104 | COM | 405 | $25,000 | thousands by filing date |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001178913-14-003523 | superseded | 2014-11-13 | acceptance time not in the bulk data set | |
| 13F-HR/A 0001178913-14-003634 | this filing | 2014-11-20 | acceptance time not in the bulk data set |