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13F-HR filed by SPHERA FUNDS MANAGEMENT LTD.

SPHERA FUNDS MANAGEMENT LTD. filed this 13F-HR for the quarter ended 2014-03-31, filed 2014-05-14, with 111 holding rows worth $438,056,000.

Accession
0001178913-14-001658
Filed
2014-05-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q1 2014

A holdings report, 114 entries on the cover page, a total value of $438,056,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $438,058,000 with VALUE read as thousands by filing date, 13F file number 028-15863. The quarter's positions are built on this report. The resolved quarter.

Other managers

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
NOVARTIS AG SPONSORED ADR66987V109ADR535,100$45,435,000thousands by filing date
GLAXOSMITHKLINE PLC-ADR37733W105SPONSORED ADR650,000$34,730,000thousands by filing date
SANOFI SA SPONSORED ADR80105N105ADR320,000$33,378,000thousands by filing date
Merck & Co.,Inc.58933Y105COM530,000$30,088,000thousands by filing date
Pfizer Inc.717081103COM854,596$27,450,000thousands by filing date
Johnson & Johnson478160104COM223,600$21,964,000thousands by filing date
Eli Lilly and Company532457108COM300,000$17,658,000thousands by filing date
Financial Select Sector SPDR Fund81369Y605SHS680,659$15,206,000thousands by filing date
Health Care Select Sector SPDR Fund81369Y209SHS159,353$9,321,000thousands by filing date
AMGEN INC.31162100 COM70,000$8,634,000thousands by filing dateThe CUSIP as filed is malformed.
Gilead Sciences,Inc.375558103COM94,000$6,661,000thousands by filing date
SEATTLE GENETICS INC812578102COM127,800$5,823,000thousands by filing date
PERRIGO CO PLC SHSG97822103Stock36,106$5,584,000thousands by filing date
BIOGEN INC COM09062X103Stock17,000$5,200,000thousands by filing date
UNITED THERAPEUTICS CORP DEL COM91307C102Stock50,000$4,702,000thousands by filing date
TJX Companies Inc872540109COM74,916$4,544,000thousands by filing date
INCYTE CORP COM45337C102Stock83,000$4,442,000thousands by filing date
COLGATE PALMOLIVE CO COM194162103Stock62,799$4,074,000thousands by filing date
NIKE,Inc. Class B654106103COM49,544$3,659,000thousands by filing date
SPDR SERIES TRUST78464A950PUT2,800$3,620,000thousands by filing dateput
Energy Select Sector SPDR Fund81369Y506SHS40,000$3,562,000thousands by filing date
BROADCOM CORP111320107CL A112,500$3,542,000thousands by filing date
SPDR INDEX SHS FDS78463X202EURO STOXX 5083,000$3,541,000thousands by filing date
ORBOTECH LTDM75253100ORD223,174$3,435,000thousands by filing date
WALGREEN CO931422109COM51,453$3,397,000thousands by filing date
CSX Corporation126408103COM116,825$3,384,000thousands by filing date
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS881624209ADR61,600$3,255,000thousands by filing date
Google38259p508COM2,864$3,192,000thousands by filing date
PRECISION CASTPARTS CORP740189105COM12,520$3,165,000thousands by filing date
SELECT SECTOR SPDR TR81369Y704INDL54,623$2,858,000thousands by filing date
CLOVIS ONCOLOGY INC189464100COM40,000$2,771,000thousands by filing date
CVS Health Corporation126650100COM35,795$2,680,000thousands by filing date
PRICELINE GRP INC741503403COM NEW2,242$2,672,000thousands by filing date
TEVA PHARMACEUTICAL INDS LTD881624909CALL3,000$2,531,000thousands by filing datecall
REGADO BIOSCIENCE INC75874Q107COM200,000$2,504,000thousands by filing date
REDHILL BIOPHARMA LTD757468103ADR1,714,880$2,428,000thousands by filing date
AQUINOX PHARMACEUTICALS INC03842B101COM190,000$2,419,000thousands by filing date
BIOMARIN PHARMACEUTICAL INC09061GAD3CNV35,000$2,387,000thousands by filing date
AERIE PHARMACEUTICALS INC00771V108COM112,500$2,384,000thousands by filing date
NPS PHARMACEUTICALS INC62936P103COM78,000$2,335,000thousands by filing date
LAS VEGAS SANDS CORP COM517834107Stock27,847$2,249,000thousands by filing date
ONCOTHYREON INC682324108COM738,336$2,208,000thousands by filing date
REXAHN PHARMACEUTICALS INC761640101COM2,006,200$2,167,000thousands by filing date
PROTHENA CORP PLC SHSG72800108Stock55,000$2,107,000thousands by filing date
NOVA LTD COMM7516K103Stock181,184$2,029,000thousands by filing date
SILICOM LTDM84116108ORD32,088$1,991,000thousands by filing date
TREVENA INC89532E109COM250,000$1,965,000thousands by filing date
GALMED PHARMACEUTICALS LTDM47238106SHS170,000$1,950,000thousands by filing date
Charles Schwab Corp808513105COM69,200$1,891,000thousands by filing date
INTRA-CELLULAR THERAPIES INC46116X101COMMON STOCK100,000$1,818,000thousands by filing date
CHECK POINT SOFTWARE TECH LTD ORDM22465104Stock26,513$1,793,000thousands by filing date
FIVE PRIME THERAPEUTICS INC.33830X104Common Stock90,000$1,769,000thousands by filing date
SUMMIT FINL GROUP INC86606G101COM10,921,656$1,753,000thousands by filing date
NCR VOYIX CORPORATION62886E108COM47,840$1,749,000thousands by filing date
GLYCOMIMETICS INC38000Q102COM106,000$1,731,000thousands by filing date
Costco Wholesale Corporation22160K105COM15,409$1,721,000thousands by filing date
FLEXION THERAPEUTICS INC33938J106COM103,955$1,710,000thousands by filing date
IGNYTA INC451731103COM205,000$1,702,000thousands by filing date
MEDIVATION INC58501NAA9NOTE25,000$1,609,000thousands by filing date
UNIQURE NVN90064101SHS100,000$1,555,000thousands by filing date
GENVEC INC NEW37246C307cs575,000$1,524,000thousands by filing date
Ampio Pharmaceuticals03209T109COM225,000$1,429,000thousands by filing date
Vertex Pharmaceuticals Incorporated92532F100COM20,000$1,414,000thousands by filing date
CYTRX CORP232828509COM PAR $.001405,000$1,413,000thousands by filing date
RELYPSA INC759531106Common Stock47,300$1,410,000thousands by filing date
IRONWOOD PHARMACEUTICALS INC46333X108COMMON STOCK112,484$1,386,000thousands by filing date
TG THERAPEUTICS INC COM88322Q108Stock200,000$1,380,000thousands by filing date
CELL THERAPEUTICS INC150934883COM NPV NEW 2012400,000$1,360,000thousands by filing date
AMBIT BIOSCIENCES CORP02318X100COM148,468$1,354,000thousands by filing date
BIOLINERX LTD-SPONS ADR09071M106SPON600,000$1,338,000thousands by filing date
INSMED INC COM PAR $.01457669307Stock70,000$1,333,000thousands by filing date
BLUEBIRD BIO INC09609G100COM57,435$1,306,000thousands by filing date
OCERA THERAPEUTICS INC COM67552A108COM121,148$1,278,000thousands by filing date
TETRALOGIC PHARMACEUTICALS COR88165U109COMMON200,000$1,276,000thousands by filing date
IMMUNOMEDICS INC452907108COM300,000$1,263,000thousands by filing date
DIPEXIUM PHARMACEUTICALS INC25456J104COM125,000$1,255,000thousands by filing date
BREAD FINANCIAL HOLDINGS INC018581108COM4,596$1,252,000thousands by filing date
CURIS INC231269101COM438,800$1,237,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW130,000$1,235,000thousands by filing date
GALECTIN THERAPEUTICS INC363225111W EXP 03/28/20180,000$1,225,000thousands by filing date
PEREGRINE PHARMACEUTICALS IN713661304COM NEW640,000$1,216,000thousands by filing date
NEKTAR THERAPEUTICS640268108COM100,000$1,212,000thousands by filing date
OMEROS CORP682143102COM100,000$1,207,000thousands by filing date
XENCOR INC98401F105COMMON STOCK100,000$1,173,000thousands by filing date
MACROGENICS INC556099109COM41,000$1,141,000thousands by filing date
GILEAD SCIENCES INC375558903COM2,000$1,140,000thousands by filing datecall
QLT INC746927102COMMON STOCK200,000$1,112,000thousands by filing date
DISCOVERY LABORATORIES INC N254668403COM NEW500,000$1,075,000thousands by filing date
STERICYCLE INC858912108COM9,439$1,072,000thousands by filing date
VANDA PHARMACEUTICALS INC921659108COM65,000$1,056,000thousands by filing date
TONIX PHARMACEUTICALS HOLDING890260201COM NEW100,000$1,041,000thousands by filing date
ELLOMAY CAPITAL LIMITEDM39927120SHS100,853$995,000thousands by filing date
KALOBIOS PHARMACEUTICALS INC48344T100COM360,000$976,000thousands by filing date
GLAXOSMITHKLINE PLC-SPON ADR37733W905COM3,000$878,000thousands by filing datecall
BIODEL INC09064M204COM283,900$775,000thousands by filing date
COMPUGEN LTD2620859 ORD69,109$726,000thousands by filing dateThe CUSIP as filed is malformed.
ORMAT TECHNOLOGIES INC686688102COM23,472$704,000thousands by filing date
ACCELERON PHARMA INC00434H108COM20,000$690,000thousands by filing date
ISHARES TR464287955PUT3,000$690,000thousands by filing dateput
F5 INC COM315616102Stock6,222$663,000thousands by filing date
CONATUS PHARMACEUTICALS INC20600T108COM80,000$651,000thousands by filing date
VERTEX PHARMACEUTICALS INC92532F900CALL500$543,000thousands by filing datecall
IMMUNOGEN INC45253H101COMMON STOCK34,500$515,000thousands by filing date
CAESARSTONE LTDM20598104ORD SHS7,830$426,000thousands by filing date
VICAL INC925602104COM300,000$387,000thousands by filing date
INSMED INC457669907CALL1,000$355,000thousands by filing datecall
IMPAX LABORATORIES INC CMN STOCK45256B901Cmn1,000$335,000thousands by filing datecall
AUXILIUM PHARMACEUTICALS INC05334D907COM935$332,000thousands by filing datecall
CORCEPT THERAPEUTICS INC218352902COM1,206$124,000thousands by filing datecall
PFIZER INC717081903CALL2,000$82,000thousands by filing datecall
CYTOKINETICS INC23282W905COM NEW131$16,000thousands by filing datecall

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001178913-14-001658this filing2014-05-14acceptance time not in the bulk data set