13F-HR filed by Rock Springs Capital Management LP
Rock Springs Capital Management LP filed this 13F-HR for the quarter ended 2022-12-31, filed 2023-02-14, with 120 holding rows worth $4,155,902,223.
- Accession
- 0001172661-23-000999
- Filer
- CIK 1595725
- Filed
- 2023-02-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2022
A holdings report, 120 entries on the cover page, a total value of $4,155,902,223 stated on the cover page (in dollars after the unit check, H1), rows summing to $4,155,902,223 with VALUE read as dollars as filed, 13F file number 028-16048. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| HUMANA INC COM | 444859102 | Stock | 426,500 | $218,449,035 | dollars as filed | |
| IMMUNOCORE HLDGS PLC ADS | 45258D105 | ADR | 3,321,066 | $189,533,237 | dollars as filed | |
| INSULET CORP COM | 45784P101 | Stock | 524,250 | $154,333,958 | dollars as filed | |
| UnitedHealth Group Inc | 91324P102 | COM | 270,000 | $143,148,600 | dollars as filed | |
| NEUROCRINE BIOSCIENCES INC | 64125C109 | COM | 1,122,500 | $134,071,400 | dollars as filed | |
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 350,000 | $132,590,500 | dollars as filed | |
| AGILON HEALTH INC | 00857U107 | COM | 7,872,500 | $127,062,150 | dollars as filed | |
| PROMETHEUS BIOSCIENCES INC | 74349U108 | COM | 1,031,550 | $113,470,500 | dollars as filed | |
| PENUMBRA INC COM | 70975L107 | Stock | 508,250 | $113,065,295 | dollars as filed | |
| EVOLENT HEALTH INC CL A | 30050B101 | Stock | 3,803,500 | $106,802,280 | dollars as filed | |
| MADRIGAL PHARMACEUTICALS INC COM | 558868105 | Stock | 348,121 | $101,042,120 | dollars as filed | |
| IDEXX LABS INC COM | 45168D104 | Stock | 207,500 | $84,651,700 | dollars as filed | |
| HORIZON THERAPEUTICS PLC | G46188101 | SHS | 739,700 | $84,177,860 | dollars as filed | |
| AGIOS PHARMACEUTICALS INC | 00847X104 | COM | 2,996,592 | $84,144,303 | dollars as filed | |
| BLUEPRINT MEDICINES CORP | 09627Y109 | COM | 1,891,510 | $82,867,053 | dollars as filed | |
| KARUNA THERAPEUTICS INC | 48576A100 | COM | 413,762 | $81,304,233 | dollars as filed | |
| Intuitive Surgical,Inc. | 46120E602 | COM | 298,500 | $79,206,975 | dollars as filed | |
| CEREVEL THERAPEUTICS HLDNG I | 15678U128 | COM | 2,506,464 | $79,053,875 | dollars as filed | |
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 332,500 | $79,018,625 | dollars as filed | |
| AKERO THERAPEUTICS INC | 00973Y108 | COM | 1,400,654 | $76,755,839 | dollars as filed | |
| ACADIA HEALTHCARE COMPANY INC COM | 00404A109 | Stock | 845,500 | $69,601,560 | dollars as filed | |
| ALIGN TECHNOLOGY INC COM | 016255101 | Stock | 302,350 | $63,765,615 | dollars as filed | |
| ACLARIS THERAPEUTICS INC COM | 00461U105 | Stock | 3,961,249 | $62,389,672 | dollars as filed | |
| ULTRAGENYX PHARMACEUTICAL IN | 90400D108 | COM | 1,290,279 | $59,778,626 | dollars as filed | |
| BAXTER INTL INC | 071813109 | COM | 1,150,000 | $58,615,500 | dollars as filed | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 436,000 | $56,496,880 | dollars as filed | |
| DEXCOM INC COM | 252131107 | Stock | 490,500 | $55,544,220 | dollars as filed | |
| ASCENDIS PHARMA A/S DKK 1.0 AD | 04351P101 | SPONSORED ADR | 425,500 | $51,966,315 | dollars as filed | |
| SEAGEN INC | 81181C104 | COM | 400,200 | $51,429,702 | dollars as filed | |
| RHYTHM PHARMACEUTICALS INC | 76243J105 | COM | 1,760,865 | $51,276,389 | dollars as filed | |
| EDWARDS LIFESCIENCES CORP COM | 28176E108 | Stock | 645,900 | $48,190,599 | dollars as filed | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 1,175,672 | $46,356,747 | dollars as filed | |
| AMYLYX PHARMACEUTICALS INC | 03237H101 | COM | 1,229,637 | $45,435,087 | dollars as filed | |
| PROTHENA CORP PLC SHS | G72800108 | Stock | 753,462 | $45,396,086 | dollars as filed | |
| EXACT SCIENCES CORP COM | 30063P105 | Stock | 887,500 | $43,940,125 | dollars as filed | |
| WEST PHARMACEUTICAL SVSC INC COM | 955306105 | Stock | 185,500 | $43,657,425 | dollars as filed | |
| NEVRO CORP | 64157F103 | COM | 1,077,900 | $42,684,840 | dollars as filed | |
| PHREESIA INC | 71944F106 | COM | 1,302,500 | $42,148,900 | dollars as filed | |
| PACIRA BIOSCIENCES INC COM | 695127100 | Stock | 1,032,600 | $39,868,686 | dollars as filed | |
| OLINK HLDG AB | 680710100 | ADR | 1,445,000 | $36,674,100 | dollars as filed | |
| MIRATI THERAPEUTICS INC | 60468T105 | COM | 805,024 | $36,475,637 | dollars as filed | |
| MIRUM PHARMACEUTICALS INC | 604749101 | COM | 1,795,733 | $35,016,794 | dollars as filed | |
| FRESHPET INC COM | 358039105 | Stock | 657,000 | $34,669,890 | dollars as filed | |
| ABCAM PLC | 000380204 | ADR USD | 2,180,000 | $33,920,800 | dollars as filed | |
| ZAI LAB LTD ADR | 98887Q104 | ADR | 1,059,700 | $32,532,790 | dollars as filed | |
| KYMERA THERAPEUTICS INC | 501575104 | COM | 1,227,779 | $30,645,364 | dollars as filed | |
| IRHYTHM HOLDINGS INC COM | 450056106 | Stock | 309,450 | $28,986,182 | dollars as filed | |
| BIOMARIN PHARMACEUTICAL INC | 09061G101 | COM | 264,500 | $27,373,105 | dollars as filed | |
| Health Care Select Sector SPDR Fund | 81369Y209 | SHS | 200,000 | $27,170,000 | dollars as filed | |
| COMPASS THERAPEUTICS INC | 20454B104 | COM | 5,333,188 | $26,825,936 | dollars as filed | |
| Mersana Therapeutics Inc | 59045L106 | Common Stock | 4,103,803 | $24,048,286 | dollars as filed | |
| SHOCKWAVE MED INC | 82489T104 | COM | 115,100 | $23,665,711 | dollars as filed | |
| LEGEND BIOTECH CORP | 52490G102 | SPONSORED ADS | 450,466 | $22,487,263 | dollars as filed | |
| BIOCRYST PHARMACEUTICALS INC COM | 09058V103 | Stock | 1,890,737 | $21,705,661 | dollars as filed | |
| AZENTA INC | 114340102 | COM | 351,500 | $20,464,330 | dollars as filed | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 443,000 | $20,298,260 | dollars as filed | |
| TRAVERE THERAPEUTICS INC | 89422G107 | COM | 951,650 | $20,013,200 | dollars as filed | |
| IMMATICS N.V | N44445109 | SHS | 2,274,784 | $19,813,369 | dollars as filed | |
| DYNAVAX TECHNOLOGIES CORP | 268158201 | COM NEW | 1,813,758 | $19,298,385 | dollars as filed | |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 421,504 | $18,786,433 | dollars as filed | |
| CONMED CORP COM | 207410101 | Stock | 205,000 | $18,171,200 | dollars as filed | |
| ANAPTYSBIO INC | 032724106 | COM | 576,600 | $17,868,834 | dollars as filed | |
| COLLEGIUM PHARMACEUTICAL INC | 19459J104 | COM | 725,000 | $16,820,000 | dollars as filed | |
| WARBY PARKER INC | 93403J106 | CL A COM | 1,218,975 | $16,443,973 | dollars as filed | |
| ACCOLADE INC | 00437E102 | COM | 1,938,000 | $15,097,020 | dollars as filed | |
| CINCOR PHARMA INC | 17240Y109 | COM | 1,116,578 | $13,722,744 | dollars as filed | |
| LIFESTANCE HEALTH GROUP INC | 53228F101 | COM | 2,700,000 | $13,338,000 | dollars as filed | |
| CHINOOK THERAPEUTICS INC | 16961L106 | COM | 507,512 | $13,296,814 | dollars as filed | |
| AMICUS THERAPEUTICS INC | 03152W109 | COM | 1,063,806 | $12,989,071 | dollars as filed | |
| VERVE THERAPEUTICS INC | 92539P101 | COM | 558,837 | $10,813,496 | dollars as filed | |
| AURA BIOSCIENCES INC | 05153U107 | COMMON STOCK | 1,019,757 | $10,707,449 | dollars as filed | |
| RELAY THERAPEUTICS INC COM | 75943R102 | Stock | 673,966 | $10,069,052 | dollars as filed | |
| HEALTH CATALYST INC | 42225T107 | COM | 929,900 | $9,884,837 | dollars as filed | |
| EDAP TMS S A | 268311107 | SPONSORED ADR | 910,000 | $9,700,600 | dollars as filed | |
| AMRYT PHARMA LTD - SPNR ADR | 03217L106 | COMMON EQUITY | 1,325,625 | $9,677,063 | dollars as filed | |
| BIOHAVEN LTD | G1110E107 | COM | 668,913 | $9,284,512 | dollars as filed | |
| NOVOCURE LTD | G6674U108 | ORD SHS | 125,000 | $9,168,750 | dollars as filed | |
| MACROGENICS INC | 556099109 | COM | 1,123,096 | $7,535,974 | dollars as filed | |
| DISC MEDICINE INC COM | 254604101 | Stock | 339,497 | $6,752,595 | dollars as filed | |
| ICOSAVAX INC | 45114M109 | COM | 781,000 | $6,201,140 | dollars as filed | |
| BIOMEA FUSION INC | 09077A106 | CMN | 730,846 | $6,161,032 | dollars as filed | |
| VIGIL NEUROSCIENCE INC | 92673K108 | COM | 471,958 | $5,899,475 | dollars as filed | |
| INVITAE CORP | 46185L103 | COM | 3,097,525 | $5,761,397 | dollars as filed | |
| PULMONX CORP | 745848101 | COM | 652,400 | $5,499,732 | dollars as filed | |
| NOVAVAX INC | 670002401 | COM NEW | 532,600 | $5,475,128 | dollars as filed | |
| GUARDANT HEALTH INC COM | 40131M109 | Stock | 200,000 | $5,440,000 | dollars as filed | |
| GAMIDA CELL LTD | M47364100 | SHS | 4,119,883 | $5,314,649 | dollars as filed | |
| F-STAR THERAPEUTICS INC | 30315R107 | COM | 751,889 | $4,751,938 | dollars as filed | |
| DESIGN THERAPEUTICS INC | 25056L103 | COM | 460,391 | $4,723,612 | dollars as filed | |
| MEREO BIOPHARMA GROUP PLC | 589492107 | CMN | 6,244,897 | $4,683,673 | dollars as filed | |
| KINNATE BIOPHARMA INC | 49705R105 | COM | 746,973 | $4,556,535 | dollars as filed | |
| BEAM THERAPEUTICS INC | 07373V105 | COM | 111,430 | $4,358,027 | dollars as filed | |
| ADAPTIMMUNE THERAPEUTICS PLC | 00653A107 | SPONDS ADR | 2,676,536 | $3,907,743 | dollars as filed | |
| ALTIMMUNE INC | 02155H200 | COM NEW | 223,255 | $3,672,545 | dollars as filed | |
| Xilio Therapeutics Inc. | 98422T100 | COM | 1,362,878 | $3,666,142 | dollars as filed | |
| PARATEK PHARMACEUTICALS INC | 699374302 | Equity | 1,734,037 | $3,242,649 | dollars as filed | |
| INOZYME PHARMA INC | 45790W108 | COM | 3,086,027 | $3,240,328 | dollars as filed | |
| GOSSAMER BIO INC | 38341PAA0 | NOTE 5.000% 6/0 | 9,573,000 | $3,096,866 | dollars as filed | principal |
| TRAVERE THERAPEUTICS INC | 761299AB2 | NOTE 2.500% 9/1 | 3,250,000 | $3,000,075 | dollars as filed | principal |
| FULCRUM THERAPEUTICS INC | 359616109 | COMMON STOCK | 384,590 | $2,799,815 | dollars as filed | |
| RENEO PHARMACEUTICALS INC | 75974E103 | COM | 1,143,185 | $2,663,621 | dollars as filed | |
| NKARTA INC | 65487U108 | COMMON STOCK | 393,389 | $2,356,400 | dollars as filed | |
| THESEUS PHARMACEUTICALS INC | 88369M101 | COM | 437,329 | $2,177,898 | dollars as filed | |
| AURINIA PHARMACEUTICALS INC COM | 05156V102 | Stock | 479,540 | $2,071,613 | dollars as filed | |
| SPRUCE BIOSCIENCES INC | 85209E109 | COM | 1,622,689 | $1,780,739 | dollars as filed | |
| LEAP THERAPEUTICS INC | 52187K101 | COM | 3,659,847 | $1,646,931 | dollars as filed | |
| NEUROCRINE BIOSCIENCES INC | 64125CAD1 | NOTE 2.250% 5/1 | 1,000,000 | $1,586,500 | dollars as filed | principal |
| AEGLEA BIOTHERAPEUTICS INC | 00773J103 | COM | 3,413,906 | $1,535,916 | dollars as filed | |
| ESSA PHARMA INC | 29668H708 | COM NEW | 524,944 | $1,322,859 | dollars as filed | |
| SPERO THERAPEUTICS INC | 84833T103 | COM | 669,533 | $1,158,292 | dollars as filed | |
| FATE THERAPEUTICS INC | 31189P102 | COM | 110,000 | $1,109,900 | dollars as filed | |
| Tempest Therapeutics, Inc. | 87978U108 | Common Stock | 823,654 | $947,202 | dollars as filed | |
| COMPUGEN LTD | M25722105 | ORD | 1,289,990 | $923,246 | dollars as filed | |
| VINCERX PHARMA INC | 92731L106 | COM NEW | 891,719 | $909,553 | dollars as filed | |
| GOSSAMER BIO INC COM | 38341P102 | Stock | 376,048 | $816,024 | dollars as filed | |
| TALPHERA INC | 00444T209 | COM NEW | 316,460 | $715,200 | dollars as filed | |
| NEVRO CORP | 64157FAC7 | NOTE 2.750% 4/0 | 500,000 | $458,750 | dollars as filed | principal |
| Applied Therapeutics Inc | 03828A101 | Common Stock | 596,680 | $453,477 | dollars as filed | |
| ATRECA INC | 04965G109 | COM | 362,530 | $290,242 | dollars as filed | |
| NUVATION BIO INC | 67080N119 | WARR | 134,028 | $19,367 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001172661-23-000999 | this filing | 2023-02-14 | acceptance time not in the bulk data set |