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13F-HR filed by Rock Springs Capital Management LP

Rock Springs Capital Management LP filed this 13F-HR for the quarter ended 2021-03-31, filed 2021-05-17, with 151 holding rows worth $4,583,741,000.

Accession
0001172661-21-001265
Filed
2021-05-17
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q1 2021

A holdings report, 151 entries on the cover page, a total value of $4,583,741,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $4,583,741,000 with VALUE read as thousands by filing date, 13F file number 028-16048. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
AGIOS PHARMACEUTICALS INC00847X104COM2,543,600$131,352,000thousands by filing date
HUMANA INC COM444859102Stock301,000$126,194,000thousands by filing date
ZAI LAB LTD ADR98887Q104ADR933,500$124,557,000thousands by filing date
ATEA PHARMACEUTICALS INC04683R106COMMON STOCK1,694,903$104,660,000thousands by filing date
UnitedHealth Group Inc91324P102COM275,000$102,319,000thousands by filing date
FIVE PRIME THERAPEUTICS INC.33830X104Common Stock2,660,822$100,233,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM1,015,000$98,709,000thousands by filing date
IMMUNOCORE HLDGS PLC ADS45258D105ADR2,292,285$97,583,000thousands by filing date
INSULET CORP COM45784P101Stock371,000$96,801,000thousands by filing date
ALIGN TECHNOLOGY INC COM016255101Stock177,500$96,122,000thousands by filing date
ACLARIS THERAPEUTICS INC COM00461U105Stock3,569,192$89,944,000thousands by filing date
Intuitive Surgical,Inc.46120E602COM120,000$88,673,000thousands by filing date
IDEXX LABS INC COM45168D104Stock180,000$88,076,000thousands by filing date
HCA Healthcare Inc40412C101COM450,000$84,753,000thousands by filing date
INVITAE CORP46185L103COM2,213,977$84,596,000thousands by filing date
NOVAVAX INC670002401COM NEW461,000$83,584,000thousands by filing date
ARGENX SE SPONSORED ADR04016X101ADR300,000$82,617,000thousands by filing date
FRESHPET INC COM358039105Stock506,500$80,437,000thousands by filing date
EXACT SCIENCES CORP COM30063P105Stock570,000$75,115,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM746,732$72,605,000thousands by filing date
PACIRA BIOSCIENCES INC COM695127100Stock1,025,000$71,842,000thousands by filing date
BEONE MEDICINES LTD SPONSORED ADS07725L102ADR200,000$69,616,000thousands by filing date
NEVRO CORP64157F103COM485,000$67,658,000thousands by filing date
IRHYTHM HOLDINGS INC COM450056106Stock432,496$60,056,000thousands by filing date
HORIZON THERAPEUTICS PLCG46188101SHS625,000$57,525,000thousands by filing date
MIRATI THERAPEUTICS INC60468T105COM323,647$55,441,000thousands by filing date
TELEFLEX INCORPORATED879369106COM130,000$54,010,000thousands by filing date
BOLT BIOTHERAPEUTICS INC097702104COM1,559,248$51,315,000thousands by filing date
ULTRAGENYX PHARMACEUTICAL IN90400D108COM450,000$51,237,000thousands by filing date
EDWARDS LIFESCIENCES CORP COM28176E108Stock582,000$48,678,000thousands by filing date
Mersana Therapeutics Inc59045L106Common Stock2,775,127$44,902,000thousands by filing date
CULLINAN THERAPEUTICS INC230031106COM1,075,912$44,833,000thousands by filing date
KARUNA THERAPEUTICS INC48576A100COM368,764$44,336,000thousands by filing date
PHREESIA INC71944F106COM850,000$44,285,000thousands by filing date
EARGO INC270087109COM851,671$42,541,000thousands by filing date
ALNYLAM PHARMACEUTICALS INC COM02043Q107Stock300,000$42,357,000thousands by filing date
COVETRUS INC22304C100COM1,400,000$41,958,000thousands by filing date
ARVINAS INC04335A105COM621,800$41,101,000thousands by filing date
ENCOMPASS HEALTH CORP COM29261A100Stock500,000$40,950,000thousands by filing date
ACADIA HEALTHCARE COMPANY INC COM00404A109Stock700,000$39,998,000thousands by filing date
PENUMBRA INC COM70975L107Stock147,500$39,911,000thousands by filing date
TRAVERE THERAPEUTICS INC89422G107COM1,475,564$36,845,000thousands by filing date
HEALTH CATALYST INC42225T107COM785,000$36,714,000thousands by filing date
ALLAKOS INC01671P100COM305,706$35,089,000thousands by filing date
SEAGEN INC81181C104COM250,000$34,715,000thousands by filing date
ARDELYX INC039697107COM5,176,561$34,269,000thousands by filing date
ASTRAZENECA PLC SPONSORED ADR046353108ADR650,000$32,318,000thousands by filing date
BIOGEN INC COM09062X103Stock113,500$31,752,000thousands by filing date
Boston Scientific Corporation101137107COM800,000$30,920,000thousands by filing date
GUARDANT HEALTH INC COM40131M109Stock200,000$30,530,000thousands by filing date
MADRIGAL PHARMACEUTICALS INC COM558868105Stock258,500$30,237,000thousands by filing date
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR233,500$30,093,000thousands by filing date
MIRUM PHARMACEUTICALS INC604749101COM1,502,800$29,785,000thousands by filing date
EVOLENT HEALTH INC CL A30050B101Stock1,445,000$29,189,000thousands by filing date
PROTHENA CORP PLC SHSG72800108Stock1,156,900$29,061,000thousands by filing date
SHOCKWAVE MED INC82489T104COM220,000$28,657,000thousands by filing date
ACCOLADE INC00437E102COM625,000$28,356,000thousands by filing date
ACADIA PHARMACEUTICALS INC004225108COM1,076,200$27,766,000thousands by filing date
PULMONX CORP745848101COM592,500$27,101,000thousands by filing date
SPRUCE BIOSCIENCES INC85209E109COM1,579,301$26,216,000thousands by filing date
ADAPTIVE BIOTECHNOLOGIES CORP COM00650F109Stock650,000$26,169,000thousands by filing date
AMARIN CORP PLC023111206SPONS ADR NEW4,195,000$26,051,000thousands by filing date
PPD INC69355F102COM675,000$25,542,000thousands by filing date
SAREPTA THERAPEUTICS INC803607100COM328,750$24,502,000thousands by filing date
EPIZYME INC29428V104COM2,802,954$24,414,000thousands by filing date
KYMERA THERAPEUTICS INC501575104COM621,777$24,162,000thousands by filing date
NOVOCURE LTDG6674U108ORD SHS175,000$23,132,000thousands by filing date
INTERSECT ENT INC46071F103COM1,080,200$22,555,000thousands by filing date
COLLEGIUM PHARMACEUTICAL INC19459J104COM920,000$21,804,000thousands by filing date
INSPIRE MED SYS INC COM457730109Stock100,000$20,699,000thousands by filing date
ABCAM PLC000380204ADR USD1,069,236$20,551,000thousands by filing date
OAK STR HEALTH INC67181A107COM375,000$20,351,000thousands by filing date
KURA ONCOLOGY INC COM50127T109Stock710,035$20,073,000thousands by filing date
BIOMARIN PHARMACEUTICAL INC09061G101COM253,500$19,142,000thousands by filing date
CYTOKINETICS INC23282WAA8NOTE 4.000%11/18,000,000$19,094,000thousands by filing dateprincipal
ROCKET PHARMACEUTICALS INC77313F106COM403,070$17,884,000thousands by filing date
SIERRA ONCOLOGY INC82640U404CMN1,017,358$17,529,000thousands by filing date
GAMIDA CELL LTDM47364100SHS2,100,300$16,991,000thousands by filing date
INOZYME PHARMA INC45790W108COM827,900$16,392,000thousands by filing date
PRELUDE THERAPEUTICS INC74065P101CMN378,195$16,387,000thousands by filing date
DYNAVAX TECHNOLOGIES CORP268158201COM NEW1,658,520$16,303,000thousands by filing date
RIGEL PHARMACEUTICALS INC766559603COMMON STOCK4,742,000$16,218,000thousands by filing date
NKARTA INC65487U108COMMON STOCK491,848$16,182,000thousands by filing date
MEREO BIOPHARMA GROUP PLC589492107CMN4,494,869$15,148,000thousands by filing date
AKERO THERAPEUTICS INC00973Y108COM521,171$15,119,000thousands by filing date
ESSA PHARMA INC29668H708COM NEW503,035$14,613,000thousands by filing date
ATHIRA PHARMA INC04746L104COM788,202$14,503,000thousands by filing date
OLINK HLDG AB680710100ADR400,000$14,400,000thousands by filing date
SPERO THERAPEUTICS INC84833T103COM965,928$14,218,000thousands by filing date
GOSSAMER BIO INC38341PAA0NOTE 5.000% 6/015,573,000$13,977,000thousands by filing dateprincipal
THERAVANCE BIOPHARMA INCG8807B106COM682,600$13,932,000thousands by filing date
CEREVEL THERAPEUTICS HLDNG I15678U128COM1,005,100$13,800,000thousands by filing date
Applied Therapeutics Inc03828A101Common Stock701,680$13,160,000thousands by filing date
TG THERAPEUTICS INC COM88322Q108Stock266,520$12,846,000thousands by filing date
RHYTHM PHARMACEUTICALS INC76243J105COM599,280$12,747,000thousands by filing date
LAKEFRONT BIOTHERAPEUTICS NV36315X101SPON ADR165,000$12,720,000thousands by filing date
MACROGENICS INC556099109COM393,479$12,532,000thousands by filing date
AEGLEA BIOTHERAPEUTICS INC00773J103COM1,577,296$12,492,000thousands by filing date
INNOVAGE HLDG CORP45784A104COM475,000$12,250,000thousands by filing date
PARATEK PHARMACEUTICALS INC699374302Equity1,684,714$11,894,000thousands by filing date
BAXTER INTL INC071813109COM140,000$11,808,000thousands by filing date
ANAPTYSBIO INC032724106COM535,232$11,534,000thousands by filing date
SHATTUCK LABS INC82024L103COMMON STOCK388,499$11,360,000thousands by filing date
CONMED CORP COM207410101Stock85,085$11,111,000thousands by filing date
PROTARA THERAPEUTICS INC74365U107COM STK689,942$10,860,000thousands by filing date
FIBROGEN INC31572Q808COM312,687$10,853,000thousands by filing date
TRANSLATE BIO INC.89374L104Common Stock649,900$10,717,000thousands by filing date
NGM BIOPHARMACEUTICALS INC62921N105COM364,800$10,605,000thousands by filing date
PROMETHEUS BIOSCIENCES INC74349U108COM574,858$10,497,000thousands by filing date
COMPUGEN LTDM25722105ORD1,219,488$10,475,000thousands by filing date
CHINOOK THERAPEUTICS INC16961L106COM673,049$10,459,000thousands by filing date
XENON PHARMACEUTICALS INC COM98420N105Stock572,500$10,248,000thousands by filing date
KINNATE BIOPHARMA INC49705R105COM326,386$10,170,000thousands by filing date
FUSION PHARMACEUTICALS INC36118A100COM948,327$10,166,000thousands by filing date
AURINIA PHARMACEUTICALS INC COM05156V102Stock781,569$10,149,000thousands by filing date
AMICUS THERAPEUTICS INC03152W109COM1,012,506$10,004,000thousands by filing date
ORION ACQUISITION CORP68626A207UNIT 02/19/20261,000,000$10,000,000thousands by filing date
DESIGN THERAPEUTICS INC25056L103COM327,250$9,785,000thousands by filing date
NURIX THERAPEUTICS INC67080M103COMMON STOCK310,950$9,667,000thousands by filing date
LEGEND BIOTECH CORP52490G102SPONSORED ADS312,618$9,072,000thousands by filing date
RELAY THERAPEUTICS INC COM75943R102Stock252,127$8,716,000thousands by filing date
ADAPTIMMUNE THERAPEUTICS PLC00653A107SPONDS ADR1,545,000$8,204,000thousands by filing date
WEST PHARMACEUTICAL SVSC INC COM955306105Stock28,500$8,031,000thousands by filing date
ATRECA INC04965G109COM453,930$6,959,000thousands by filing date
CHIASMA INC16706W102COM2,174,583$6,806,000thousands by filing date
TRILLIUM THERAPEUTICS INC COM NEW89620X506Stock620,800$6,667,000thousands by filing date
ACELRX PHARMACEUTICALS INC00444T100COM3,785,457$6,435,000thousands by filing date
FATE THERAPEUTICS INC31189P102COM70,000$5,772,000thousands by filing date
CONSTELLATION PHARMACEUTICALS INC.210373106Common Stock232,000$5,426,000thousands by filing date
DEXCOM INC COM252131107Stock15,000$5,391,000thousands by filing date
PHASEBIO PHARMACEUTICALS INC717224109COM1,553,974$5,377,000thousands by filing date
GALERA THERAPEUTICS EQUICLASS EQUITY36338D108COMMON STOCK568,252$5,012,000thousands by filing date
NUVATION BIO INC COM CL A67080N101Stock402,088$4,202,000thousands by filing date
ROYALTY PHARMA PLCG7709Q104SHS CLASS A80,000$3,490,000thousands by filing date
TRAVERE THERAPEUTICS INC761299AB2NOTE 2.500% 9/13,250,000$3,360,000thousands by filing dateprincipal
BCLS ACQUISITION CORPG0904B105CMN309,000$3,266,000thousands by filing date
POSEIDA THERAPEUTICS INC73730P108COM289,754$2,767,000thousands by filing date
CONNECT BIOPHARMA HLDGS LTD207523101SHS119,114$2,204,000thousands by filing date
LIFESCI ACQUISITION II CORP53229E103COM206,200$2,091,000thousands by filing date
PARDES BIOSCIENCES INC COM30318F100Stock209,332$2,085,000thousands by filing date
EUCRATES BIOMEDICAL ACQU CORG3141W114UNIT 10/23/2027206,000$2,063,000thousands by filing date
TURMERIC ACQUISITION CORPG9127T116UNT206,000$2,060,000thousands by filing date
JIYA ACQUISITION CORP47760M102CMN206,200$2,029,000thousands by filing date
POPULATION HEALTH INVS CO ING71716123UNIT 99/99/9999201,044$2,020,000thousands by filing date
MOONLAKE IMMUNOTHERAPEUTICSG4444C102COM154,500$1,576,000thousands by filing date
THERAVANCE BIOPHARMA88339KAA0NOTE 3.250%11/01,500,000$1,526,000thousands by filing dateprincipal
RADIUS HEALTH INC750469AA6NOTE1,500,000$1,401,000thousands by filing dateprincipal
NEUROCRINE BIOSCIENCES INC64125CAD1NOTE 2.250% 5/11,000,000$1,354,000thousands by filing dateprincipal
PACIRA BIOSCIENCES695127AD2NOTE 2.375% 4/01,000,000$1,211,000thousands by filing dateprincipal
NEVRO CORP64157FAC7NOTE 2.750% 4/0500,000$771,000thousands by filing dateprincipal
NUVATION BIO INC67080N119WARR134,028$358,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001172661-21-001265this filing2021-05-17acceptance time not in the bulk data set